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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 61, Issue 4, pp. 427 - 436
Objectives The aim of this study was to test the hypothesis that elevated nonfasting remnant cholesterol is a causal risk factor for ischemic heart disease... 
Cardiovascular | Internal Medicine | atherosclerosis | cardiovascular disease | lipoproteins | myocardial infarction | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | PREDICTIVE-VALUE | MENDELIAN RANDOMIZATION | PARTICLE CHOLESTEROL | DIABETES-MELLITUS | DENSITY-LIPOPROTEIN CHOLESTEROL | NONFASTING TRIGLYCERIDES | CARDIOVASCULAR-DISEASE | HDL CHOLESTEROL | CORONARY-ARTERY-DISEASE | Myocardial Ischemia - genetics | Myocardial Ischemia - metabolism | Lipoproteins, HDL - genetics | Humans | Middle Aged | Risk Factors | Lipoproteins, HDL - metabolism | Genotype | Male | Data Collection | Cholesterol - metabolism | Cholesterol - genetics | Genetic Variation - physiology | Triglycerides - metabolism | Time Factors | Denmark - epidemiology | Female | Aged | Triglycerides - genetics | Causality | Odds Ratio | Myocardial Ischemia - epidemiology | Analysis and chemistry | Blood cholesterol | Low density lipoproteins | Atherosclerosis | Myocardial ischemia | Universities and colleges | Heart attack | Risk factors | Blood | Cholesterol | Heart | Lipoproteins (low density) | Cardiovascular disease | Density | Confidence intervals | Variables | Randomization | Ischemia | Population | Blood pressure | Heart diseases | Lipoproteins (high density) | Age | Deoxyribonucleic acid--DNA | Hypertension | Enzymes | Health risks | Triglycerides | Risk analysis | Apolipoproteins | Low density lipoprotein | Coronary artery disease | Studies | Genetic variance | Lipoproteins | Diabetes | Cardiovascular diseases
Journal Article
by Traylor, Matthew, MSc and Farrall, Martin, FRCPath and Holliday, Elizabeth G, PhD and Sudlow, Cathie, FRCP and Hopewell, Jemma C, PhD and Cheng, Yu-Ching, PhD and Fornage, Myriam, PhD and Ikram, M Arfan, MD and Malik, Rainer, PhD and Bevan, Steve, PhD and Thorsteinsdottir, Unnur, PhD and Nalls, Mike A, PhD and Longstreth, WT, MD and Wiggins, Kerri L, MS and Yadav, Sunaina, MSc and Parati, Eugenio A, MD and DeStefano, Anita L, PhD and Worrall, Bradford B, MD and Kittner, Steven J, MD and Khan, Muhammad Saleem, MSc and Reiner, Alex P, MD and Helgadottir, Anna, MD and Achterberg, Sefanja, PhD and Fernandez-Cadenas, Israel, PhD and Abboud, Sherine, MD and Schmidt, Reinhold, MD and Walters, Matthew, MD and Chen, Wei-Min, PhD and Ringelstein, E Bernd, MD and O'Donnell, Martin, MD and Ho, Weang Kee, PhD and Pera, Joanna, MD and Lemmens, Robin, MD and Norrving, Bo, MD and Higgins, Peter, MRCP and Benn, Marianne, MD and Sale, Michele, PhD and Kuhlenbäumer, Gregor, MD and Doney, Alexander S F, PhD and Vicente, Astrid M, PhD and Delavaran, Hossein, MD and Algra, Ale, MD and Davies, Gail, PhD and Oliveira, Sofia A, PhD and Palmer, Colin N A, PhD and Deary, Ian, PhD and Schmidt, Helena, MD and Pandolfo, Massimo, MD and Montaner, Joan, MD and Carty, Cara, PhD and de Bakker, Paul I W, PhD and Kostulas, Konstantinos, MD and Ferro, Jose M, MD and van Zuydam, Natalie R, MSc and Valdimarsson, Einar, MD and Nordestgaard, Børge G, MD and Lindgren, Arne, MD and Thijs, Vincent, MD and Slowik, Agnieszka, MD and Saleheen, Danish, MD and Paré, Guillaume, MD and Berger, Klaus, MD and Thorleifsson, Gudmar, PhD and Hofman, Albert, MD and Mosley, Thomas H, PhD and Mitchell, Braxton D, PhD and Furie, Karen, MD and Clarke, Robert, FRCP and Levi, Christopher, MD and Seshadri, Sudha, MD and Gschwendtner, Andreas, MD and Boncoraglio, Giorgio B, MD and Sharma, Pankaj, PhD and Bis, Joshua C, PhD and Gretarsdottir, Solveig, PhD and Psaty, Bruce M and Rothwell, Peter M, FMedSci and Rosand, Jonathan, MD and Meschia, James F, MD and Stefansson, Kari, MD and Dichgans, Martin, MD and Markus, Hugh S, Dr and WTCCC 2 and Australian Stroke Genetics Collabo and Int Stroke Genetics Consortium and International Stroke Genetics Consortium and Australian Stroke Genetics Collaborative, Wellcome Trust Case Control Consortium 2 (WTCCC2) and EpiHealth: Epidemiology for Health and Lund University and Neurologi, Lund and Lunds universitet and Neurology, Lund
The Lancet Neurology, ISSN 1474-4422, 2012, Volume 11, Issue 11, pp. 951 - 962
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 62, Issue 20, pp. 1908 - 1909
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2017, Volume 140, Issue 6, pp. 1616 - 1621.e3
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2010, Volume 55, Issue 25, pp. 2833 - 2842
Objectives The aim of this study was to examine the effect of PCSK9 R46L on low-density lipoprotein cholesterol (LDL-C), risk of ischemic heart disease (IHD),... 
Cardiovascular | Internal Medicine
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2010, Volume 56, Issue 10, pp. 789 - 795
Objectives The purpose of this study was to test whether the association of C-reactive protein (CRP) with increased risk of atrial fibrillation is a robust and... 
Cardiovascular | Internal Medicine | atrial fibrillation | C-reactive protein | genetics | Mendelian randomization | inflammation | Analysis and chemistry | Low density lipoproteins | Atrial fibrillation | Genetics | Universities and colleges | Blood
Journal Article
by Walter, Klaudia and Min, Josine L and Huang, Jie and Crooks, Lucy and Memari, Yasin and McCarthy, Shane and Perry, John and Xu, Changjiang and Futema, Marta and Lawson, Daniel and Iotchkova, Valentina and Schiffels, Stephan and Henicks, Auey E and Danecek, Petr and Li, Rui and Floyd, James and Wain, Louise and Barroso, Inês and Humphries, Steve and Hurles, Matthew and Zeggini, Eleftheria and Barrett, Jeffrey C and Plagnol, Vincent and Richards, Brent and Greenwood, Celia and Timpson, Nicholas and Durbin, Richard and Bala, Senduran and Clapham, Peter and Coates, Guy and Cox, Tony and Daly, Allan and Du, Yuanping and Edkins, Ted and Ellis, Peter and Flicek, Paul and Guo, Xiaosen and Guo, Xueqin and Huang, Liren and Jackson, David K and Joyce, Chris and Keane, Thomas and Kolb-Kokocinski, Anja and Langford, Cordelia and Li, Yingrui and Liang, Jieqin and Lin, Hong and Liu, Ryan and Maslen, John and Muddyman, Dawn and Quail, Michael A and Stalker, Jim and Sun, Jianping and Tian, Jing and Wang, Guangbiao and Wang, Jun and Wang, Yu and Wong, Kim and Zhang, Pingbo and Birney, Ewan and Boustred, Chris and Chen, Lu and Clement, Gail and Cocca, Massimiliano and Smith, G.D and Day, Ian N.M and Day-Williams, Aaron and Down, Thomas and Dunham, David and Evans, David M and Gaunt, Tom and Geihs, Matthias and Hart, Deborah and Howie, Bryan and Hubbard, Tim and Hysi, Pirro and Jamshidi, Yalda and Karczewski, Konrad and Kemp, John and Lachance, Genevieve and Lek, Monkol and Lopes, Margarida and MacArthur, Daniel G and Marchini, Jonathan and Mangino, Massimo and Mathieson, Iain and Metrustry, Sarah and Moayyeri, Alireza and Northstone, Kate and Panoutsopoulou, Kalliope and Paternoster, Lavinia and Quaye, Lydia and Ring, Susan and Ritchie, Graham R.S and Shihab, Hashem A and Shin, So-Youn and Small, Kerrin and Artigas, M.S and Soranzo, Nicole and Southam, Lorraine and ... and UCLEB Consortium and UK10K Consortium and The UK10K Consortium
Nature: international weekly journal of science, ISSN 0028-0836, 10/2015, Volume 526, Issue 7571, pp. 82 - 89
Journal Article
by Tachmazidou, Ioanna and Süveges, Dániel and Min, Josine L and Ritchie, Graham R.S and Steinberg, Julia and Walter, Klaudia and Iotchkova, Valentina and Schwartzentruber, Jeremy and Huang, Jie and Memari, Yasin and McCarthy, Mark I and McCarthy, Shane and Crawford, Andrew A and Bombieri, Cristina and Cocca, Massimiliano and Farmaki, Aliki-Eleni and Gaunt, Tom R and Jousilahti, Pekka and Kooijman, Marjolein N and Lehne, Benjamin and Malerba, Giovanni and Männistö, Satu and Matchan, Angela and Medina-Gomez, Carolina and Metrustry, Sarah J and Nag, Abhishek and Ntalla, Ioanna and Paternoster, Lavinia and Rayner, Nigel W and Sala, Cinzia and Scott, William R and Scott, Robert A and Shihab, Hashem A and Southam, Lorraine and St Pourcain, Beate and Traglia, Michela and Trajanoska, Katerina and Zaza, Gialuigi and Zhang, Weihua and Artigas, María S and Bansal, Narinder and Benn, Marianne and Chen, Zhongsheng and Danecek, Petr and Lin, Wei-Yu and Locke, Adam and Luan, Jian’an and Manning, Alisa K and Mulas, Antonella and Sidore, Carlo and Tybjaerg-Hansen, Anne and Varbo, Anette and Zoledziewska, Magdalena and Finan, Chris and Hatzikotoulas, Konstantinos and Hendricks, Audrey E and Kemp, John P and Moayyeri, Alireza and Panoutsopoulou, Kalliope and Szpak, Michal and Wilson, Scott G and Boehnke, Michael and Cucca, Francesco and Di Angelantonio, Emanuele and Langenberg, Claudia and Lindgren, Cecilia and Morris, Andrew P and Nordestgaard, Børge G and Tobin, Martin D and Wareham, Nicholas J and Burton, Paul and Chambers, John C and Smith, George Davey and Dedoussis, George and Felix, Janine F and Franco, Oscar H and Gambaro, Giovanni and Gasparini, Paolo and Hammond, Christopher J and Hofman, Albert and Jaddoe, Vincent W.V and Kleber, Marcus and Kooner, Jaspal S and Perola, Markus and Relton, Caroline and Ring, Susan M and Rivadeneira, Fernando and Salomaa, Veikko and Spector, Timothy D and Stegle, Oliver and Toniolo, Daniela and Uitterlinden, André G and Barroso, Inês and Greenwood, Celia M.T and Perry, John R.B and Walker, Brian R and Butterworth, Adam S and Xue, Yali and Durbin, Richard and Small, Kerrin S and ... and SpiroMeta Consortium and UK10KConsortium and GoT2D Consortium and ArcOGEN Consortium and Understanding Soc Sci Grp and Understanding Society Scientific Group and UK10K Consortium and arcOGEN Consortium
The American Journal of Human Genetics, ISSN 0002-9297, 06/2017, Volume 100, Issue 6, pp. 865 - 884
Journal Article
by Tachmazidou, I and Süveges, D and Min, JL and Ritchie, GRS and Steinberg, J and Walter, K and Iotchkova, V and Schwartzentruber, J and Huang, J and Memari, Y and McCarthy, Shane Alan and Crawford, AA and Bombieri, C and Cocca, M and Farmaki, A-E and Gaunt, TR and Jousilahti, P and Kooijman, MN and Lehne, B and Malerba, G and Männistö, S and Matchan, A and Medina-Gomez, C and Metrustry, SJ and Nag, A and Ntalla, I and Paternoster, L and Rayner, NW and Sala, C and Scott, WR and Shihab, HA and Southam, L and St Pourcain, B and Traglia, M and Trajanoska, K and Zaza, G and Zhang, W and Artigas, MS and Bansal, Narinder and Benn, M and Chen, Z and Danecek, P and Lin, W-Y and Locke, A and Luan, Jian'an and Manning, AK and Mulas, A and Sidore, C and Tybjaerg-Hansen, A and Varbo, A and Zoledziewska, M and Finan, C and Hatzikotoulas, K and Hendricks, AE and Kemp, JP and Moayyeri, A and Panoutsopoulou, K and Szpak, M and Wilson, SG and Boehnke, M and Cucca, F and Di Angelantonio, Emanuele and Langenberg, Claudia and Lindgren, C and McCarthy, MI and Morris, AP and Nordestgaard, BG and Scott, RA and Tobin, MD and Wareham, Nicholas John and SpiroMeta Consortium and GoT2D Consortium and Burton, P and Chambers, JC and Smith, GD and Dedoussis, G and Felix, JF and Franco, OH and Gambaro, G and Gasparini, P and Hammond, CJ and Hofman, A and Jaddoe, VWV and Kleber, M and Kooner, JS and Perola, M and Relton, C and Ring, SM and Rivadeneira, F and Salomaa, V and Spector, TD and Stegle, O and Toniolo, D and Uitterlinden, AG and arcOGEN Consortium and Understanding Society Scientific Group and UK10K Consortium and Barroso, Ines and Greenwood, CMT and Perry, John Richard and ...
ISSN 0002-9297, 2017
Deep sequence-based imputation can enhance the discovery power of genome-wide association studies by assessing previously unexplored variation across the... 
imputation | UK10K | anthropometry | next-generation whole-genome sequencing | DXA traits | UK Biobank | genetic association study
Journal Article
by Guo, Shengwen and Lai, Chunren and Wu, Congling and Cen, Guiyin and Hariharan, A and Vijayakumari, Anupa A and Aarabi, Mohammad Hadi and Aballi, John and Nour, Abd Elazeim Abd Alla Mohamed and Abdelaziz, Mohammed and Abdolalizadeh, AmirHussein and Abdollahi, Mahsa and Abdul Aziz, Siti Aishah and Salam, Amritha Abdul and Abdulaziz, Nidhal and Abdulkadir, Ahmed and Abdullah, Sachal and Abdullah, Osama and Abrigo, Jill and Adachi, Noriaki and Adamson, Christopher and Adduru, Viraj and Adel, Tameem and Aderghal, Karim and Ades-Aron, Benjamin and Adeyosoye, Michael and Adlard, Paul and Srinivasa, Ag and Aganj, Iman and Agarwal, Ayush and Agarwal, Anupam and Agarwal, Anchit and Aguero, Cinthya and Aguiar, Pablo and Ahdidan, Jamila and Ahmad, Fayyaz and Ahmad, Rziwan and Ahmadi, Hessam and Ahmed, Nisar and Sid, Farid Ahmed and Ai, Edward and Ai, Qing and Aicha, Benyahia and Aitharaju, Sai and Aiyer, Aditya and Akkus, Zeynettin and Akodad, Sanae and Akramifard, Hamid and Aksman, Leon and Aktas, Said and Al-Janabi, Omar and Al-Nuaimi, Ali and AlAila, BahaaEddin and Alakwaa, Fadhl and Alam, Saruar and Alam, Fakhre and Alam Zaidi, Syed Farhan and Alan, Wiener and Alansari, Mukhtar and Alareqi, Ebrahim and Alberdi, Ane and Albsoul, Mohammad and Alderson, Thomas and Aleem, Hassan and Alex, Aishwarya and Alexander, Jacob and Alexopoulos, Panagiotis and Alfoldi, Jessica and Ali, Ayesha and Ali, Imdad and Alimoradian, Shirin and Aljabar, Paul and Aljabbouli, Hasan and Aljovic, Almir and Allen, Genevera and Alliende, Luz Maria and Almaguel, Frankis and Almgren, Hannes and Montes, Carmen Alonso and Alowaisheq, Tasneem and Alryalat, Saif Aldeen and Alsado, Majd and Alsaedi, Abdalrahman and Alshehri, Haifa and Altaf, Tooba and Altendahl, Marie and Altmann, Ane and Alvand, Ashkan and Filho, Manoel Alves and Alzubi, Raid and Amaral, Robert and Ambatipudi, Mythri and Amernath, Remya and Amlien, Inge and Amoroso, Nicola and Amri, Hakima and Anastasiou, Athanasios and Anbarasi, Jani and Anbarjafari, Gholamreza and Anderson, Wes and ... and Alzheimer's Dis Neuroimaging and Alzheimer's Disease Neuroimaging Initiative and The Alzheimer's Disease Neur