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1. Full Text In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs
by Tefferi, Ayalew, MD and Kantarjian, Hagop, MD and Rajkumar, S. Vincent, MD and Baker, Lawrence H., DO and Adamson, John W., MD and Advani, Ranjana Hira, MD and Allison, James, MD and Antman, Karen H., MD and Bast, Robert C., MD and Bennett, John M., MD and Benz, Edward J., MD and Berliner, Nancy, MD and Bhatia, Ravi, MD and Bhatia, Smita, MD and Bhojwani, Deepa, MD and Blanke, Charles D., MD and Bloomfield, Clara D., MD and Bosserman, Linda, MD and Byrd, John C., MD and Cabanillas, Fernando, MD and Canellos, George Peter, MD and Chabner, Bruce A., MD and Chanan-Khan, Asher, MD and Cheson, Bruce, MD and Cohn, Susan L., MD and Colon-Otero, Gerardo, MD and Cortes, Jorge, MD and Coutre, Steven, MD and Cristofanilli, Massimo, MD and Curran, Walter J., MD and Daley, George Q., MD, PhD and DeAngelo, Daniel J., MD, PhD and Deeg, H. Joachim, MD and Einhorn, Lawrence H., MD and Erba, Harry P., MD, PhD and Esteva, Francisco J., MD, PhD and Estey, Elihu, MD and Fidler, Isaiah J., DVM, PhD and Foran, James, MD and Forman, Stephen, MD and Freireich, Emil, MD and Fuchs, Charles, MD, MPH and George, James N., MD and Gertz, Morie A., MD and Golomb, Harvey, MD and Greenberg, Peter, MD and Gutterman, Jordan, MD and Handin, Robert I., MD and Hoff, Paulo Marcelo, MD and Hoffman, Ronald, MD and Horowitz, Mary, MD, MS and Hortobagyi, Gabriel N., MD and Hudis, Clifford, MD and Issa, Jean Pierre, MD and Kantoff, Philip W., MD and Kaushansky, Kenneth, MD and Khayat, David, MD, PhD and Kipps, Thomas J., MD, PhD and Kripke, Margaret, PhD and Kyle, Robert A., MD and Larson, Richard A., MD and Lawrence, Theodore S., MD, PhD and Link, Michael P., MD and Lippman, Scott M., MD and Lonial, Sagar, MD and Lyman, Gary H., MD, MPH and Markman, Maurie, MD and Messinger, Yoav, MD and Mulvey, Therese M., MD and Perez-Soler, Roman, MD and Pollock, Raphael, MD, PhD and Prchal, Josef, MD and Press, Oliver, MD, PhD and Radich, Jerald, MD and Rai, Kanti, MD and Rosenberg, Saul A., MD and Rugo, Hope, MD and Runowicz, Carolyn D., MD and Sandmaier, Brenda M., MD and Saven, Alan, MD and Schafer, Andrew I., MD and Schiffer, Charles, MD and Sekeres, Mikkael A., MD, MS and Silver, Richard T., MD and Siu, Lillian L., MD and Steensma, David P., MD and Stewart, F. Marc, MD and Stock, Wendy, MD, MA and Stone, Richard, MD and Storb, Rainer, MD and Strong, Louise C., MD and Tallman, Martin S., MD and Thompson, Michael, MD, PhD and Ueno, Naoto T., MD, PhD and Van Etten, Richard A., MD, PhD and Vose, Julie M., MD, MBA and Wiernik, Peter H., MD and Younes, Anas, MD and Zelenetz, Andrew D., MD, PhD and LeMaistre, Charles A., MD
Mayo Clinic proceedings, ISSN 0025-6196, 2015, Volume 90, Issue 8, pp. 996 - 1000
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Drug Costs | United States - epidemiology | Neoplasms - economics | Humans | Patient Participation | Patient Advocacy | Antineoplastic Agents - economics | Neoplasms - epidemiology | Prescription Fees | Neoplasms - drug therapy | Antimitotic agents | Cancer patients | Patient outcomes | Economic aspects | Dosage and administration | Drug therapy | Antineoplastic agents | Index Medicus | Abridged Index Medicus
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2. Full Text Lymphatic and Other Vascular Malformative/Overgrowth Disorders Are Caused by Somatic Mutations in PIK3CA
by Luks, Valerie L., BS and Kamitaki, Nolan and Vivero, Matthew P., BA and Uller, Wibke, MD and Rab, Rashed, BA and Bovée, Judith V.M.G., MD, PhD and Rialon, Kristy L., MD and Guevara, Carlos J., MD and Alomari, Ahmad I., MD and Greene, Arin K., MD, MMSc and Fishman, Steven J., MD and Kozakewich, Harry P.W., MD and Maclellan, Reid A., MD, MMSc and Mulliken, John B., MD and Rahbar, Reza, MD and Spencer, Samantha A., MD and Trenor, Cameron C., MD and Upton, Joseph, MD and Zurakowski, David, PhD and Perkins, Jonathan A., DO and Kirsh, Andrew, PhD and Bennett, James T., MD, PhD and Dobyns, William B., MD and Kurek, Kyle C., MD, MMSc and Warman, Matthew L., MD and McCarroll, Steven A., PhD and Murillo, Rudy, MD
The Journal of pediatrics, ISSN 0022-3476, 2015, Volume 166, Issue 4, pp. 1048 - 1054.e5
Pediatrics | Life Sciences & Biomedicine | Science & Technology | Klippel-Trenaunay-Weber Syndrome - genetics | Vascular Malformations - metabolism | Lymphatic Abnormalities - genetics | Humans | Klippel-Trenaunay-Weber Syndrome - diagnosis | Abnormalities, Multiple | Child, Preschool | Lymphatic Abnormalities - metabolism | Infant | Male | Phosphatidylinositol 3-Kinases - metabolism | DNA - genetics | Phosphatidylinositol 3-Kinases - genetics | Class I Phosphatidylinositol 3-Kinases | Polymerase Chain Reaction | Vascular Malformations - diagnosis | Female | High-Throughput Nucleotide Sequencing | Klippel-Trenaunay-Weber Syndrome - metabolism | Lymphatic Abnormalities - diagnosis | Mutation | Vascular Malformations - genetics | Child | Index Medicus | Abridged Index Medicus | Klippel-Trenaunay syndrome | PIK3CA | somatic mutation | lymphatic malformation
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3. Full Text Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
by Fenaux, Pierre, Prof and Mufti, Ghulam J, Prof and Hellstrom-Lindberg, Eva, Prof and Santini, Valeria, MD and Finelli, Carlo, MD and Giagounidis, Aristoteles, MD and Schoch, Robert, MD and Gattermann, Norbert, MD and Sanz, Guillermo, MD and List, Alan, Prof and Gore, Steven D, Prof and Seymour, John F, MBBS and Bennett, John M, Prof and Byrd, John, Prof and Backstrom, Jay, MD and Zimmerman, Linda, BSN and McKenzie, David, MS and Beach, CL, PharmD and Silverman, Lewis R, MD and for the International Vidaza High-Risk MDS Survival Study Group and Int Vidaza High-Risk MDS Survival and International Vidaza High-Risk MDS Survival Study Group
The lancet oncology, ISSN 1470-2045, 2009, Volume 10, Issue 3, pp. 223 - 232
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Azacitidine - adverse effects | Humans | Middle Aged | Proportional Hazards Models | Male | Antimetabolites, Antineoplastic - therapeutic use | Myelodysplastic Syndromes - mortality | Aged, 80 and over | Adult | Female | Aged | Myelodysplastic Syndromes - drug therapy | Azacitidine - therapeutic use | Antimitotic agents | Medical colleges | Care and treatment | Oncology, Experimental | Clinical trials | Research | Comparative analysis | Antineoplastic agents | Myelodysplastic syndromes | Cancer | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study
by Finkel, Richard S, Dr and Chiriboga, Claudia A, MD and Vajsar, Jiri, MD and Day, John W, MD and Montes, Jacqueline, EdD and De Vivo, Darryl C, MD and Yamashita, Mason, MD and Rigo, Frank, PhD and Hung, Gene, MD and Schneider, Eugene, MD and Norris, Daniel A, PhD and Xia, Shuting, MS and Bennett, C Frank, PhD and Bishop, Kathie M, PhD
The Lancet (British edition), ISSN 0140-6736, 2016, Volume 388, Issue 10063, pp. 3017 - 3026
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Injections, Spinal | Humans | RNA, Messenger - genetics | Patient Safety | Spinal Muscular Atrophies of Childhood - drug therapy | Female | Male | Oligonucleotides - adverse effects | Mutation | Oligonucleotides - administration & dosage | Oligonucleotides - pharmacokinetics | Care and treatment | RNA | Children's hospitals | Spinal muscular atrophy | Clinical trials | Analysis | Proteins | Spinal cord | Genetic disorders | Drug therapy | Drug dosages | Index Medicus | Abridged Index Medicus
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5. Full Text Expert Consensus on the Prescribing Practice and Management of Adverse Events Associated With the Treatment of Patients Taking Macitentan for PAH: A Delphi Consensus Study
by Rahaghi, Franck, MD and Alnuaimat, Hassan, MD and Awdish, Rana, MD and Balasubramanian, Vijay, MD and Bourge, Robert, MD and Burger, Charles, MD and Butler, John, MD and Cauthen, C. Gregory, MD and Chakinala, Murali, MD and deBoisblanc, Bennett, MD and Eggert, Michael, MD and Engel, Peter, MD and Feldman, Jeremy, MD and McConnell, J. Wesley, MD and Park, Myung, MD and Sager, Jeffrey, MD and Sood, Namita, MD and Palevsky, Harold, MD
Chest, ISSN 0012-3692, 2016, Volume 150, Issue 4, pp. 1148A - 1148A
Pulmonary/Respiratory
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6. Full Text Reducing Health Inequities in the U.S
by Sampson, Uchechukwu K.A and Kaplan, Robert M and Cooper, Richard S and Diez Roux, Ana V and Marks, James S and Engelgau, Michael M and Peprah, Emmanuel and Mishoe, Helena and Boulware, L. Ebony and Felix, Kaytura L and Califf, Robert M and Flack, John M and Cooper, Lisa A and Gracia, J. Nadine and Henderson, Jeffrey A and Davidson, Karina W and Krishnan, Jerry A and Lewis, Tené T and Sanchez, Eduardo and Luban, Naomi L and Vaccarino, Viola and Wong, Winston F and Wright, Jackson T and Meyers, David and Ogedegbe, Olugbenga G and Presley-Cantrell, Letitia and Chambers, David A and Belis, Deshirée and Bennett, Glen C and Boyington, Josephine E and Creazzo, Tony L and de Jesus, Janet M and Krishnamurti, Chitra and Lowden, Mia R and Punturieri, Antonello and Shero, Susan T and Young, Neal S and Zou, Shimian and Mensah, George A
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2016, Volume 68, Issue 5, pp. 517 - 524
health information exchange | social determinants of health | T4 research | health services accessibility | health policy | translation research
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7. Full Text A Randomized Clinical Trial of Therapeutic Hypothermia Mode during Transport for Neonatal Encephalopathy
by Akula, Vishnu Priya, MD and Joe, Priscilla, MD and Thusu, Kajori, MD and Davis, Alexis S., MD, MS, Epi and Tamaresis, John S., PhD, MS and Kim, Sunhwa, MD and Shimotake, Thomas K., MD and Butler, Stephen, MD and Honold, Jose, MD and Kuzniewicz, Michael, MD and DeSandre, Glenn, MD and Bennett, Mihoko, PhD and Gould, Jeffrey, MD, MPH and Wallenstein, Matthew B., MD and Van Meurs, Krisa, MD
The Journal of pediatrics, ISSN 0022-3476, 2015, Volume 166, Issue 4, pp. 856 - 861.e2
Pediatrics | Life Sciences & Biomedicine | Science & Technology | Asphyxia Neonatorum - therapy | Prognosis | Follow-Up Studies | Humans | Male | Infant, Newborn, Diseases - therapy | Body Temperature - physiology | Intensive Care Units, Neonatal | Brain Diseases - therapy | Hypothermia, Induced - methods | Asphyxia Neonatorum - complications | Female | Brain Diseases - etiology | Transportation of Patients - methods | Infant, Newborn | Infants (Newborn) | Health maintenance organizations | Clinical trials | Medical colleges | Health aspects | Hypothermia | Index Medicus | Abridged Index Medicus
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8. Full Text Safety and tolerability of eltrombopag versus placebo for treatment of thrombocytopenia in patients with advanced myelodysplastic syndromes or acute myeloid leukaemia: a multicentre, randomised, placebo-controlled, double-blind, phase 1/2 trial
by Platzbecker, Uwe, Prof and Wong, Raymond S M, MD and Verma, Amit, Prof and Abboud, Camille, Prof and Araujo, Sergio, MD and Chiou, Tzeon-Jye, MD and Feigert, John, MD and Yeh, Su-Peng, MD and Götze, Katharina, MD and Gorin, Norbert-Claude, Prof and Greenberg, Peter, Prof and Kambhampati, Suman, MD and Kim, Yoo-Jin, Prof and Lee, Je-Hwan, Prof and Lyons, Roger, MD and Ruggeri, Marco, MD and Santini, Valeria, MD and Cheng, Gregory, Prof and Jang, Jun Ho, MD and Chen, Chien-Yuan, MD and Johnson, Brendan, PhD and Bennett, John, Prof and Mannino, Frank, PhD and Kamel, Yasser Mostafa, MD and Stone, Nicole, PhD and Dougherty, Souria, BS and Chan, Geoffrey, MD and Giagounidis, Aristoteles, MD
The Lancet. Haematology, ISSN 2352-3026, 2015, Volume 2, Issue 10, pp. e417 - e426
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Hematology | Science & Technology | Hydrazines - therapeutic use | Pyrazoles - therapeutic use | Benzoates - therapeutic use | Double-Blind Method | Humans | Middle Aged | Male | Treatment Outcome | Leukemia, Myeloid, Acute - complications | Myelodysplastic Syndromes - complications | Thrombocytopenia - complications | Receptors, Thrombopoietin - agonists | Thrombocytopenia - drug therapy | Aged, 80 and over | Leukemia, Myeloid, Acute - drug therapy | Adult | Female | Aged | Myelodysplastic Syndromes - drug therapy | Index Medicus
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9. Full Text Serrated lesions of the appendix frequently harbor KRAS mutations and not BRAF mutations indicating a distinctly different serrated neoplastic pathway in the appendix
by Pai, Rish K., MD, PhD and Hartman, Douglas J., MD and Gonzalo, David H., MD and Lai, Keith K., MD and Downs-Kelly, Erinn, MD and Goldblum, John R., MD and Liu, Xiuli, MD and Patil, Deepa T., MD and Bennett, Ana E., MD and Plesec, Thomas P., MD and Kuan, Shih-Fan, MD, PhD and Nikiforova, Marina N., MD and Shadrach, Bonnie and Pai, Reetesh K., MD
Human pathology, ISSN 0046-8177, 2014, Volume 45, Issue 2, pp. 227 - 235
Pathology | Sessile serrated adenoma | Hyperplastic polyp | Serrated polyp | KRAS | BRAF | Appendix | Life Sciences & Biomedicine | Science & Technology | ras Proteins - genetics | Intestinal Polyps - genetics | Proto-Oncogene Proteins p21(ras) | Appendix - pathology | Proto-Oncogene Proteins B-raf - genetics | Humans | Intestinal Polyps - pathology | Appendiceal Neoplasms - genetics | Proto-Oncogene Proteins - genetics | Appendiceal Neoplasms - pathology | Antimitotic agents | Genetic aspects | Gene mutations | Antineoplastic agents | Harbors | Analysis | Inflammatory bowel disease | Mutation | Colorectal cancer | Colleges & universities | Classification | Tumors | Index Medicus
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10. Full Text New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
by Gustafsson, Stefan and Buchkovich, Martin L and Na, Jianbo and Esko, Tõnu and Evans, David M and Haring, Robin and Locke, Adam and Lu, Chen and Mägi, Reedik and Perry, John R. B and Pers, Tune H and Qi, Qibin and Scott, William R and Shungin, Dmitry and Westra, Harm-Jan and Zhang, Weihua and Zhao, Jing Hua and Bellis, Claire and Borodulin, Katja and Cederholm, Tommy and Choh, Auey C and Curran, Joanne E and Havulinna, Aki S and Hernandez, Dena and Hillege, Hans and Ittermann, Till and Liu, Youfang and Loh, Marie and Lyytikäinen, Leo-Pekka and Medina-Gomez, Carolina and Nielson, Carrie M and Oozageer, Laticia and Paternoster, Lavinia and Polašek, Ozren and Steinhagen-Thiessen, Elisabeth and Swart, Karin M. A and Taittonen, Leena and Tanaka, Toshiko and van der Velde, Nathalie and Verweij, Niek and Forrester, Terrence and Grarup, Niels and Jackson, Anne U and Kuulasmaa, Teemu and Luan, Jian'an and Mahajan, Anubha and Ried, Janina S and Stancáková, Alena and Wagner, Peter J and Demirkan, Ayse and Döring, Angela and Gudnason, Vilmundur and Kiel, Douglas P and Menni, Cristina and O'Connell, Jeffrey R and Shuldiner, Alan R and Vandenput, Liesbeth and Vollenweider, Peter and Boettcher, Yvonne and Grallert, Harald and Hingorani, Aroon and McKenzie, Colin A and Pedersen, Oluf and Wareham, Nicholas J and Bertram, Lars and Bouchard, Claude and Cho, Nam H and Eriksson, Johan G and Ferrucci, Luigi and Gansevoort, Ron T and Hansen, Torben and Kajantie, Eero and Liu, Yongmei and Pérusse, Louis and Rao, D. C and Rice, Treva K and Stumvoll, Michael and Tranah, Gregory J and Tremblay, Angelo and Uitterlinden, Ané G and van der Harst, Pim and Vohl, Marie-Claude and Völzke, Henry and Walker, Mark and Wild, Sarah and Cupples, L. Aienne and Dehghan, Abbas and Fatemifar, Ghazaleh and Fox, Caroline and Furey, Terrence S and Karpe, Freik and Kaplan, Robert C and Ohlsson, Claes and Ong, Ken K and Prokopenko, Inga and Richards, J. Brent and Schadt, Eric E and Widén, Elisabeth and Willer, Cristen J and Kilpeläinen, Tuomas Oskari and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Nature communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, pp. 10495 - 10495
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Drosophila melanogaster - metabolism | Genetic Predisposition to Disease | Genome-Wide Association Study | Animals | Humans | Gene Expression Regulation - physiology | Adiposity - genetics | Drosophila melanogaster - genetics | Heart Diseases - genetics | Gene Knockdown Techniques | Quantitative Trait Loci - genetics | Index Medicus | Genetik | C reactive protein; CRTC1 protein; glucose; GRB14 protein; high density lipoprotein cholesterol; IGF2BP1 protein; insulin; leptin; low density lipoprotein cholesterol; PLA2G6 protein; protein; triacylglycerol; unclassified drug | Medicinsk genetik | Medical Genetics | Näringslära | Genetics | Nutrition and Dietetics | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes | Humane Voeding | Onderwijsinstituut | CS Onderwijsinstituut | HNE Nutrition and Disease | Chair Nutrition and Disease | Humane Voeding & Gezondheid | HNE Nutrition and Health over the Lifecourse | Human Nutrition & Health | Nutrition and Disease | HNE Voeding en Gezondheid in de Levenscyclus | Afdeling Humane voeding | VLAG | Chair Nutrition and Health over the Lifecourse | Global Nutrition | Human Nutrition (HNE) | Human Nutrition | Voeding en Ziekte | Wereldvoeding | HNE Voeding en Ziekte
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