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Neuron, ISSN 0896-6273, 08/2019, Volume 103, Issue 4, pp. 547 - 549
Parkinson’s disease is a neurodegenerative movement disorder; however, peripheral symptoms can arise decades prior. In this issue of , provide evidence that... 
Brain | Animal models | Parkinson's disease | Neurodegenerative diseases | Neurons | Pathogenesis | Nervous system | Synuclein | Pathology | Hypotheses | Neurodegeneration | Movement disorders | Animal cognition
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2010, Volume 107, Issue 21, pp. 9747 - 9752
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2013, Volume 123, Issue 12, pp. 5389 - 5400
Brain aging is associated with diminished circadian clock output and decreased expression of the core clock proteins, which regulate many aspects of cellular... 
MEDICINE, RESEARCH & EXPERIMENTAL | NERVOUS-SYSTEM | CYCLOOXYGENASE-2 | RHYTHMS | IN-VIVO | ADAPTATION | GENE-EXPRESSION | COMPONENTS | BMAL1 | BRAIN | NPAS2 | Neurons - pathology | Oxidative Stress | Neuroglia - pathology | Nerve Tissue Proteins - deficiency | Cerebral Cortex - pathology | Nerve Degeneration - physiopathology | Nerve Degeneration - genetics | Period Circadian Proteins - deficiency | CLOCK Proteins - deficiency | Mice, Neurologic Mutants | Gliosis - pathology | ARNTL Transcription Factors - deficiency | RNA Interference | Neurons - metabolism | Corpus Striatum - pathology | Basic Helix-Loop-Helix Transcription Factors - deficiency | Period Circadian Proteins - physiology | Basic Helix-Loop-Helix Transcription Factors - physiology | CLOCK Proteins - physiology | Gliosis - genetics | Nerve Tissue Proteins - physiology | Oxidation-Reduction | Brain - physiopathology | Mice, Inbred C57BL | Circadian Rhythm - genetics | Gene Expression Regulation - physiology | Circadian Rhythm - physiology | Hippocampus - pathology | Mice, Knockout | Animals | Aging - physiology | Homeostasis - physiology | Brain - pathology | Sleep Disorders, Circadian Rhythm - physiopathology | Neuroglia - metabolism | Locomotion - physiology | ARNTL Transcription Factors - physiology | Homeostasis - genetics | Circadian rhythms | Physiological aspects | Homeostasis | Nervous system | Degeneration | Research | Brain | Oxidative stress | Neurodegeneration | Rodents | Circadian rhythm | Behavior | Kinases | Gene expression | Age
Journal Article
Science, ISSN 0036-8075, 11/2000, Volume 290, Issue 5493, pp. 985 - 989
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2018, Volume 13, Issue 9, p. e0204367
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2017, Volume 12, Issue 9, pp. e0184262 - e0184262
Abnormal accumulation of alpha-synuclein (alpha Syn) has been linked to endoplasmic-reticulum (ER) stress, defective intracellular protein/vesicle trafficking,... 
UBIQUITIN LIGASE | MULTIDISCIPLINARY SCIENCES | EARLY SECRETORY PATHWAY | IN-VIVO | GOLGI-APPARATUS | ENDOPLASMIC-RETICULUM | AMYLOID PRECURSOR PROTEIN | GAMMA-SECRETASE | LEWY BODIES | RAT MODEL | PARKINSONS-DISEASE | Brain Diseases - metabolism | Cell Line | Membrane Glycoproteins - metabolism | Humans | Endosomal Sorting Complexes Required for Transport - metabolism | Ubiquitin - metabolism | Ubiquitin-Protein Ligases - metabolism | Endoplasmic Reticulum - metabolism | Protein Transport | Alzheimer Disease - metabolism | Amyloid beta-Protein Precursor - metabolism | HEK293 Cells | Protein Domains | Nedd4 Ubiquitin Protein Ligases | Parkinson Disease - metabolism | Lewy Bodies - metabolism | Mutation | Proteasome Endopeptidase Complex - metabolism | alpha-Synuclein - metabolism | Care and treatment | Dosage and administration | Dopamine | Parkinson's disease | Research | Ubiquitin-proteasome system | Ubiquitin | Retrieval | Brain | Yeast | Toxicity | Trafficking | Parkinsons disease | Acetylcysteine | Cytotoxicity | Tissues | Synuclein | Retention | Autophagy | Degradation | Proteins | Fibrillogenesis | Protein transport | Movement disorders | Ubiquitin-protein ligase | Neurodegenerative diseases | Mutants | Lewy bodies | Medicine | Neurology | Brain research | Effectors | Quality control | Proteasomes | β-Amyloid | Endoplasmic reticulum | Dementia | Index Medicus
Journal Article