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Journal Article
by Matejcic, M and Saunders, EJ and Dadaev, T and Brook, MN and Wang, K and Sheng, X and Al Olama, AA and Schumacher, FR and Ingles, SA and Govindasami, K and Benlloch, S and Berndt, SI and Albanes, D and Koutros, S and Muir, K and Stevens, VL and Gapstur, SM and Tangen, CM and Batra, J and Clements, J and Gronberg, H and Pashayan, N and Schleutker, J and Wolk, A and West, C and Mucci, L and Kraft, P and Cancel-Tassin, G and Sorensen, KD and Maehle, L and Grindedal, EM and Strom, SS and Neal, DE and Hamdy, FC and Donovan, JL and Travis, RC and Hamilton, RJ and Rosenstein, B and Lu, YJ and Giles, GG and Kibel, AS and Vega, A and Bensen, JT and Kogevinas, M and Penney, KL and Park, JY and Stanford, JL and Cybulski, C and Nordestgaard, BG and Brenner, H and Maier, C and Kim, J and Teixeira, MR and Neuhausen, SL and De Ruyck, K and Razack, A and Newcomb, LF and Lessel, D and Kaneva, R and Usmani, N and Claessens, F and Townsend, PA and Gago-Dominguez, M and Roobol, MJ and Menegaux, F and Khaw, KT and Cannon-Albright, LA and Pandha, H and Thibodeau, SN and Schaid, DJ and Wiklund, F and Chanock, SJ and Easton, DF and Eeles, RA and Kote-Jarai, Z and Conti, DV and Haiman, CA and Henderson, BE and Stern, MC and Thwaites, A and Guy, M and Whitmore, I and Morgan, A and Fisher, C and Hazel, S and Livni, N and Cook, M and Fachal, L and Weinstein, S and Freeman, LEB and Hoover, RN and Machiela, MJ and Lophatananon, A and Carter, BD and Goodman, P and Moya, L and Srinivasan, S and Kedda, MA and Yeadon, T and Eckert, A and ... and PRACTICAL Consortium and Medicinska fakulteten and Urologi och andrologi and Institutionen för kirurgisk och perioperativ vetenskap and Umeå universitet
NATURE COMMUNICATIONS, ISSN 2041-1723, 01/2019, Volume 10
Journal Article
by Dadaev, T and Saunders, E.J and Newcombe, B and Anokian, E and Leongamornlert, D.A and Brook, R.H and Cieza-Borrella, C and Mijuskovic, M and Wakerell, S and Olama, A.A.A and Schumacher, Freick R and Berndt, Sonja and Benlloch, Sara and Ahmed, M and Goh, C and Sheng, X and Zhang, Z and Muir, K and Govindasami, K and Lophatananon, A and Stevens, V.L and Gapstur, Susan M and Carter, B.D and Tangen, Catherine M and Goodman, P and Thompson, Ian and Batra, J and Chambers, S and Moya, L and Clements, J and Horvath, L and Tilley, W and Risbridger, G and Grönberg, Henrik and Aly, M and Nordström, T and Pharoah, Paul and Pashayan, N and Schleutker, J and Tammela, Teuvo and Sipeky, C and Auvinen, Anssi and Albanes, Demetrius and Weinstein, S and Wolk, Kerstin and Hakansson, N and West, C and Dunning, Alison and Burnet, N and Mucci, L and Giovannucci, E and Aniole, Gerald and Cussenot, O and Cancel-Tassin, G and Koutros, S and Freeman, L.E.B and Sorensen, K.D and Orntoft, Torben and Borre, M and Maehle, L and Grindedal, E.M and Neal, David and Donovan, Jenny and Hamdy, Freddie and Martin, Richard M and Travis, Simon and Key, T.J and Hamilton, R.J and Fleshner, Neil and Finelli, Antonio and Ingles, Sue and Stern, M.C and Rosenstein, Barry S and Kerns, Sarah L and Ostrer, Harry and Lu, Y.-J and Zhang, H.-W and Feng, N and Mao, X and Guo, X and Wang, G and Sun, Z and Giles, G.G and Southey, M.C and MacInnis, R.J and Fitzgerald, L.M and Kibel, Adam and ke, B.F and Vega, A and Gómez-Caamaño, A and Fachal, L and Szulkin, R and Eklund, M and Kogevinas, Manolis and Llorca, J and Castaño-Vinyals, G and Penney, K.L and Stampfer, Meir J and Park, J.Y and Sellers, T.F and ... and PRACTICAL Prostate Canc Assoc Grp and PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Ortopedi and Uppsala universitet and Institutionen för kirurgiska vetenskaper
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2256 - 19
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2015, Volume 112, Issue 18, pp. 5714 - 5719
Polyunsaturated fatty acids (PUFAs) affect cardiac excitability. Kv7.1 and the beta-subunit KCNE1 form the cardiac I-Ks channel that is central for cardiac... 
Kv7.1 | Antiarrhythmic | KCNE1 | KCNQ1 | I Ks | MULTIDISCIPLINARY SCIENCES | antiarrhythmic | DEATH | I-Ks | TRIAL | VOLTAGE SENSOR | LONG QT SYNDROME | GATED ION CHANNELS | FISH-OIL | KCNQ1 POTASSIUM CHANNELS | K+ CHANNEL | MODULATION | Clinical Medicine | Kv7.1; KCNQ1; KCNE1; I-Ks; antiarrhythmic | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Journal Article
by Matejcic, M and Saunders, E.J and Dadaev, T and Brook, R.H and Wang, K and Sheng, X and Olama, A.A.A and Schumacher, Freick and Ingles, Sue and Govindasami, K and Benlloch, Sara and Berndt, Sonja and Albanes, Demetrius and Koutros, S and Muir, K and Stevens, V.L and Gapstur, Susan M and Tangen, Catherine M and Batra, J and Clements, J and Grönberg, Henrik and Pashayan, N and Schleutker, J and Wolk, Kerstin and West, C and Mucci, L and Kraft, Peter and Cancel-Tassin, G and Sorensen, K.D and Maehle, L and Grindedal, E.M and Strom, S and Neal, David and Hamdy, Freddie and Donovan, Jenny and Travis, Simon and Hamilton, R.J and Rosenstein, Barry S and Lu, Y.-J and Giles, G.G and Kibel, Adam and Vega, A and Bensen, J.T and Kogevinas, Manolis and Penney, K.L and Park, J.Y and Stanford, J.L and Cybulski, Cezary and Nordestgaard, Børge and Brenner, Hermann and Maier, C and Kim, Jongoh and Teixeira, P.J and Neuhausen, Susan and De Ruyck, K and Razack, A and Newcomb, L.F and Lessel, D and Kaneva, R and Usmani, Nawaid and Claessens, F and Townsend, P.A and Dominguez, M.G and Roobol-Bouts, Monique and Menegaux, Florence and Khaw, K.-T and Cannon-Albright, Lisa and Pandha, H and Thibodeau, S.N and Schaid, D and Wiklund, Freik and Chanock, S.J and Easton, Douglas and Eeles, R.A and Kote-Jarai, Z and Conti, Giario and Haiman, Christopher and PRACTICAL Consortium and PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Ortopedi and Uppsala universitet and Institutionen för kirurgiska vetenskaper
Nature Communications, ISSN 2041-1723, 11/2018, Volume 9, Issue 1, pp. 4616 - 11
Journal Article
by Matejcic, Marco and Saunders, Edward J and Dadaev, Tokhir and Brook, Mark N and Wang, Kan and Sheng, Xin and Olama, Ali Amin Al and Schumacher, Fredrick R and Ingles, Sue A and Govindasami, Koveela and Benlloch, Sara and Berndt, Sonja I and Albanes, Demetrius and Koutros, Stella and Muir, Kenneth and Stevens, Victoria L and Gapstur, Susan M and Tangen, Catherine M and Batra, Jyotsna and Clements, Judith and Gronberg, Henrik and Pashayan, Nora and Schleutker, Johanna and Wolk, Alicja and West, Catharine and Mucci, Lorelei and Kraft, Peter and Cancel-Tassin, Géraldine and Sorensen, Karina D and Maehle, Lovise and Grindedal, Eli M and Strom, Sara S and Neal, David E and Hamdy, Freddie C and Donovan, Jenny L and Travis, Ruth C and Hamilton, Robert J and Rosenstein, Barry and Lu, Yong-Jie and Giles, Graham G and Kibel, Adam S and Vega, Ana and Bensen, Jeanette T and Kogevinas, Manolis and Penney, Kathryn L and Park, Jong Y and Stanford, Janet L and Cybulski, Cezary and Nordestgaard, Børge G and Brenner, Hermann and Maier, Christiane and Kim, Jeri and Teixeira, Manuel R and Neuhausen, Susan L and De Ruyck, Kim and Razack, Azad and Newcomb, Lisa F and Lessel, Davor and Kaneva, Radka and Usmani, Nawaid and Claessens, Frank and Townsend, Paul A and Gago-Dominguez, Manuela and Roobol, Monique J and Menegaux, Florence and Khaw, Kay-Tee and Cannon-Albright, Lisa A and Pandha, Hardev and Thibodeau, Stephen N and Schaid, Daniel J and Wiklund, Fredrik and Chanock, Stephen J and Easton, Douglas F and Eeles, Rosalind A and Kote-Jarai, Zsofia and Conti, David V and Haiman, Christopher A and PRACTICAL Consortium and The PRACTICAL Consortium
Nature communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, pp. 382 - 5
The original version of this Article contained an error in the spelling of the author Manuela Gago-Dominguez, which was incorrectly given as Manuela G.... 
Health risk assessment | Prostate cancer | Prostate | Health risks
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 08/2011, Volume 28, Issue 1, pp. 13 - 24
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 12/2018, Volume 9, p. 1409
A variety of polycyclic pyridines have been proposed as inhibitors of the small conductance calcium-activated potassium (SK) channel. To this group belongs... 
K-Ca | blocker | small conductance calcium-activated potassium channels | SK channels | CA2+-ACTIVATED K+ CHANNELS | COMPLEXES | REPOLARIZATION | BLOCKERS | BBP | GATING MODULATION | PHARMACOLOGY & PHARMACY | 2,6-bis(2-benzimidazolyl)pyridine | polycyclic pyridine | Pyridine | Potassium channels | Research | KCa2 | 6-bis(2-benzimidazolyl)pyridine
Journal Article
eLife, ISSN 2050-084X, 09/2016, Volume 5, Issue 2016
About 300 loss-of-function mutations in the IKs channel have been identified in patients with Long QT syndrome and cardiac arrhythmia. How specific mutations... 
Taurine | Arrhythmia | Channel gating | Cardiomyocytes | Fluorometry | Molecular modelling | Voltage | Long QT syndrome | Mutation | Sensors | Gating | Heart diseases | Potassium
Journal Article