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1. Full Text Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis
by Jansen, W.J and Ossenkoppele, R and Knol, D.L and Tijms, B.M and Scheltens, P.J and Verhey, F.R.J and Visser, P.J and Aalten, P and Aarsland, D and Alcolea, D and Alexander, M and Almdahl, I.S and Arnold, S.E and Baldeiras, I and Barthel, H and Berckel, B.N. van and Bibeau, K and Blennow, K and Brooks, D.J and Buchem, M.A. van and Camus, V and Cavedo, E and Chen, K and Chetelat, G and Cohen, A.D and ezga, A and Engelborghs, S and Fagan, A.M and Fladby, T and Fleisher, A.S and Flier, W.M. van der and Ford, L and Forster, S and Fortea, J and Foskett, N and Frederiksen, K.S and Freund-Levi, Y and Frisoni, G.B and Froelich, L and Gabryelewicz, T and Gill, K.D and Gkatzima, O and Gomez-Tortosa, E and Gordon, M.F and Grimmer, T and Hampel, H and Hausner, L and Hellwig, S and Herukka, S.K and Hildebrandt, H and Ishihara, L and Ivanoiu, A and Jagust, W.J and Johannsen, P and Kandimalla, R and Kapaki, E and Klimkowicz-Mrowiec, A and Klunk, W.E and Kohler, S and Koglin, N and Kornhuber, J and Kramberger, M.G and Laere, K. Van and Landau, S.M and Lee, D.Y and Leon, M and Lisetti, V and Lleo, A and Madsen, K and Maier, W and Marcusson, J and Mattsson, N and Mendonca, A. de and Meulenbroek, O.V and Meyer, P.T and Mintun, M.A and Mok, V and Molinuevo, J.L and Mollergard, H.M and Morris, J.C and Mroczko, B and Mussele, S. Van der and Na, D.L and Newberg, A and Nordberg, A and Nordlund, A and Novak, G.P and Paraskevas, G.P and Parnetti, L and Perera, G and Peters, O and Popp, J and Prabhakar, S and Rabinovici, G.D and Ramakers, I.H and Rami, L and Oliveira, C.R and Rinne, J.O and Roigue, K.M and Roiguez-Roiguez, E and ... and Amyloid Biomarker Study Grp and Amyloid Biomarker Study Group and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Jama : Journal of the American Medical Association, ISSN 0098-7484, 2015, Volume 313, Issue 19, pp. 1924 - 1938
IMPORTANCE: Cerebral amyloid-beta aggregation is an early pathological event in Alzheimer disease (AD), starting decades before dementia onset. Estimates of... 
OLDER PERSONS | POPULATION | MEDICINE, GENERAL & INTERNAL | CEREBROSPINAL-FLUID BIOMARKERS | COHORT | MILD COGNITIVE IMPAIRMENT | DIAGNOSTIC-CRITERIA | BETA-AMYLOIDOSIS | ASSOCIATION | PIB PET | ALZHEIMER-DISEASE PATHOLOGY | Apolipoprotein E4 - genetics | Dementia - pathology | Prevalence | Age Factors | Humans | Middle Aged | Risk Factors | Biomarkers - analysis | Genotype | Male | Positron-Emission Tomography | Cognitive Dysfunction - pathology | Cerebrospinal Fluid - chemistry | Aged, 80 and over | Amyloid beta-Peptides - analysis | Brain - pathology | Adult | Female | Aged | Usage | Analysis | Amyloidosis | Cognition | Research | Biological markers | Risk factors | Meta-analysis | Prevalence studies (Epidemiology) | Pathology | Medical research | Neurological disorders | Dementia | Brain | Neurosciences | pathology | Biological Markers | 80 and over | genetics | Amyloid beta-Peptides | Neurovetenskaper | chemistry | Apolipoprotein E4 | Cerebrospinal Fluid | analysis | Mild Cognitive Impairment
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2. Full Text Association of Cerebral Amyloid-beta Aggregation With Cognitive Functioning in Persons Without Dementia
by Jansen, W.J and Ossenkoppele, R and Tijms, B.M and Fagan, A.M and Hansson, O and Klunk, W.E and Flier, W.M. van der and Villemagne, V.L and Frisoni, G.B and Fleisher, A.S and Lleo, A and Mintun, M.A and Wallin, A and Engelborghs, S and Na, D.L and Chetelat, G and Molinuevo, J.L and Landau, S.M and Mattsson, N and Kornhuber, J and Sabri, O and Rowe, C.C and Parnetti, L and Popp, J and Fladby, T and Jagust, W.J and Aalten, P and Lee, D.Y and Vandenberghe, R and Oliveira, C. de and Kapaki, E and Froelich, L and Ivanoiu, A and Gabryelewicz, T and Verbeek, M.M and Sanchez-Juan, P and Hildebrandt, H and Camus, V and Zboch, M and Brooks, D.J and ezga, A and Rinne, J.O and Newberg, A and Mendonca, A. de and Sarazin, M and Rabinovici, G.D and Madsen, K and Kramberger, M.G and Nordberg, A and Mok, V and Mroczko, B and Wolk, D.A and Meyer, P.T and Tsolaki, M and Scheltens, P and Verhey, F.R.J and Visser, P.J and Aarsland, D and Alcolea, D and Alexander, M and Almdahl, I.S and Arnold, S.E and Baldeiras, I and Barthel, H and Berckel, B.N. van and Blennow, K and Buchem, M.A. van and Cavedo, E and Chen, K and Chipi, E and Cohen, A.D and Forster, S and Fortea, J and Frederiksen, K.S and Freund-Levi, Y and Gkatzima, O and Gordon, M.F and Grimmer, T and Hampel, H and Hausner, L and Hellwig, S and Herukka, S.K and Johannsen, P and Klimkowicz-Mrowiec, A and Kohler, S and Koglin, N and Laere, K. Van and Leon, M and Lisetti, V and Maier, W and Marcusson, J and Meulenbroek, O and Mollergard, H.M and Morris, J.C and Nordlund, A and Novak, G.P and Paraskevas, G.P and Perera, G and Peters, O and Ramakers, I., et al and Amyloid Biomarker Study Grp and Amyloid Biomarker Study Group and Klinisk minnesforskning and Lund University and MultiPark: Multidisciplinary research focused on Parkinson´s disease and Clinical Memory Research and Lunds universitet and Brain Injury After Cardiac Arrest
JAMA Psychiatry, ISSN 2168-622X, 2018, Volume 75, Issue 1, pp. 84 - 95
Importance: Cerebral amyloid-beta aggregation is an early event in Alzheimer disease (AD). Understanding the association between amyloid aggregation and... 
INDIVIDUALS | LIFE-SPAN | MEMORY PERFORMANCE | METAANALYSIS | PSYCHIATRY | PRECLINICAL ALZHEIMERS-DISEASE | APOE | BURDEN | DECLINE | AGE | IMPAIRMENT | Alzheimer Disease - physiopathology | Cognition Disorders - physiopathology | Cross-Sectional Studies | Brain - physiopathology | Humans | Middle Aged | Memory, Episodic | Male | Reference Values | Mental Status and Dementia Tests | Positron-Emission Tomography | Cognitive Dysfunction - physiopathology | Alzheimer Disease - diagnosis | Cognition Disorders - diagnosis | Amyloid beta-Peptides - cerebrospinal fluid | Cognitive Dysfunction - psychology | Female | Aged | Cognitive Dysfunction - diagnosis | Alzheimer Disease - psychology | Cognition Disorders - psychology | Online First | Original Investigation | Research | Clinical Medicine | No dementia | Medical and Health Sciences | Medicin och hälsovetenskap | amyloid-β | cognitive functioning | Klinisk medicin | Geriatrik | Geriatrics
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3. Full Text Impact of molecular imaging on the diagnostic process in a memory clinic
by Ossenkoppele, Rik and Prins, Niels D and Pijnenburg, Yolande A.L and Lemstra, Afina W and van der Flier, Wiesje M and Adriaanse, Sofie F and Windhorst, Albert D and Handels, Ron L.H and Wolfs, Claire A.G and Aalten, Pauline and Verhey, Frans R.J and Verbeek, Marcel M and van Buchem, Mark A and Hoekstra, Otto S and Lammertsma, Adriaan A and Scheltens, Philip and van Berckel, Bart N.M
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2013, Volume 9, Issue 4, pp. 414 - 421
Abstract Background [11 C]Pittsburgh compound B ([11 C]PIB) and [18 F]-2-fluoro-2-deoxy-D-glucose ([18 F]FDG) PET measure fibrillar amyloid-β load and glucose... 
Neurology | [11C]PIB | [18F]FDG | MCI | Alzheimer’s disease | FTD | Lewy body dementia | SMC | PET | Memory clinic | Alzheimer's disease | FDG-PET | CEREBRAL GLUCOSE-METABOLISM | AMYLOID DEPOSITION | RESEARCH CRITERIA | [C-11]PIB | FRONTOTEMPORAL DEMENTIA | [F-18]FDG | MILD COGNITIVE IMPAIRMENT | ALZHEIMERS ASSOCIATION WORKGROUPS | PITTSBURGH COMPOUND-B | CLINICAL NEUROLOGY | NATIONAL INSTITUTE | POSITRON-EMISSION-TOMOGRAPHY | Brain - diagnostic imaging | Prospective Studies | Dementia - psychology | Follow-Up Studies | Lewy Body Disease - diagnosis | Aniline Compounds | Humans | Middle Aged | Dementia - diagnosis | Male | Molecular Imaging | Frontotemporal Dementia - psychology | Lewy Body Disease - psychology | Positron-Emission Tomography | Alzheimer Disease - diagnosis | Sensitivity and Specificity | Thiazoles | Female | France | Radiopharmaceuticals | Alzheimer Disease - psychology | Dementia - diagnostic imaging | Memory Disorders - diagnostic imaging | Frontotemporal Dementia - diagnostic imaging | Diagnosis, Differential | Outpatient Clinics, Hospital - statistics & numerical data | Treatment Outcome | Frontotemporal Dementia - diagnosis | Lewy Body Disease - diagnostic imaging | Disease Progression | Memory Disorders - etiology | Fluorodeoxyglucose F18 | Aged | Alzheimer Disease - diagnostic imaging | Fluorine Radioisotopes | Early Diagnosis | Carbon Radioisotopes | Glucose metabolism | Neurosciences | Amyloid beta-protein | Diagnosis | Glucose | Dextrose
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4. Full Text Cerebral Level of vGlut1 is Increased and Level of Glycine is Decreased in TgSwDI Mice
by Timmer, N.M and Metaxas, A and van der Stelt, I and Kluijtmans, L.A.J and van Berckel, B.N and Verbeek, M.M
Journal of Alzheimer's Disease, ISSN 1387-2877, 2014, Volume 39, Issue 1, pp. 89 - 101
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5. Full Text Cerebral level of vGlut1 is increased and level of glycine is decreased in TgSwDI mice
by Timmer, N.M and Metaxas, A and Stelt, I. van der and Kluijtmans, L.A and Berckel, B.N. van and Verbeek, M.M
Journal of Alzheimer'S Disease, ISSN 1387-2877, 2014, Volume 39, Issue 1, pp. 89 - 101
Amyloid-beta (Abeta) deposition, one of the main hallmarks of Alzheimer's disease (AD), has been linked to glutamatergic dysfunction, i.e., increased... 
TgSwDI mice | autoradiography | glycine | amino acid analysis | amyloid-β | vesicular glutamate transporter 1 | western blot | Alzheimer's disease | glutamate | ALZHEIMERS-DISEASE | COGNITIVE IMPAIRMENT | AMYLOID-BETA-PROTEIN | NEUROSCIENCES | PREFRONTAL CORTEX | amyloid-beta | VESICULAR GLUTAMATE TRANSPORTERS | MOUSE MODEL | EARLY-ONSET | CULTURED ASTROCYTES | PRECURSOR PROTEIN | TRANSGENIC MICE | Glycine - metabolism | Vesicular Glutamate Transport Protein 1 - metabolism | Cerebellum - metabolism | Mice, Inbred C57BL | Receptors, N-Methyl-D-Aspartate - metabolism | Mice, Transgenic | Cerebral Cortex - metabolism | Disease Progression | Autoradiography | Hippocampus - metabolism | Animals | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Glutamic Acid - metabolism | Mice | Aging - metabolism | Disease Models, Animal
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6. Full Text Prevalence of the apolipoprotein E epsilon4 allele in amyloid beta positive subjects across the spectrum of Alzheimer's disease
by Mattsson, N and Groot, C. de and Jansen, W.J and Landau, S.M and Villemagne, V.L and Engelborghs, S and Mintun, M.M and Lleo, A and Molinuevo, J.L and Jagust, W.J and Frisoni, G.B and Ivanoiu, A and Chetelat, G and Oliveira, C. de and Roigue, K.M and Kornhuber, J and Wallin, A and Klimkowicz-Mrowiec, A and Kandimalla, R and Popp, J and Aalten, P.P and Aarsland, D and Alcolea, D and Almdahl, I.S and Baldeiras, I and Buchem, M.A. van and Cavedo, E and Chen, K and Cohen, A.D and Forster, S and Fortea, J and Frederiksen, K.S and Freund-Levi, Y and Gill, K.D and Gkatzima, O and Grimmer, T and Hampel, H and Herukka, S.K and Johannsen, P and Laere, K. Van and Leon, M.J. de and Maier, W and Marcusson, J and Meulenbroek, O.V and Mollergard, H.M and Morris, J.C and Mroczko, B and Nordlund, A and Prabhakar, S and Peters, O and Rami, L and Roiguez-Roiguez, E and Roe, C.M and Ruther, E and Santana, I and Schroder, J and Seo, S.W and Soininen, H and Spiru, L and Stomrud, E and Struyfs, H and Teunissen, C.E and Verhey, F.R.J and Vos, S.J.B and Waalwijk van Doorn, L.L.C. van and Waldemar, G and Wallin, A.K and Wiltfang, J and Vandenberghe, R and Brooks, D.J and Fladby, T and Rowe, C.C and ezga, A and Verbeek, M.M and Sarazin, M and Wolk, D.A and Fleisher, A.S and Klunk, W.E and Na, D.L and Sanchez-Juan, P and Lee, D.Y and Nordberg, A and Tsolaki, M and Camus, V and Rinne, J.O and Fagan, A.M and Zetterberg, H and Blennow, K and Rabinovici, G.D and Hansson, O and Berckel, B.N. van and Flier, W.M. van der and Scheltens, P and Visser, P.J and Ossenkoppele, R
Alzheimer's & Dementia, ISSN 1552-5260, 2018, Volume 14, pp. 913 - 924
INTRODUCTION: Apolipoprotein E (APOE) epsilon4 is the major genetic risk factor for Alzheimer's disease (AD), but its prevalence is unclear because earlier... 
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7. Full Text SA2.1 Imaging the pathology of Alzheimer's disease: focus on amyloid imaging
by van Berckel, B.N
Parkinsonism and Related Disorders, ISSN 1353-8020, 2008, Volume 14, pp. S10 - S10
Neurology
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8. Full Text Amyloid imaging in clinical trials
by Ossenkoppele, R and Prins, N.D and van Berckel, B.N
Alzheimer's Research & Therapy, ISSN 1758-9193, 2013, Volume 5, Issue 4, pp. 36 - 36
The possibility to map amyloid-beta, the Alzheimer's disease hallmark protein, in vivo opens the application for amyloid imaging in clinical trials with... 
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9. Full Text SNM practice guideline for dopamine transporter imaging with 123I-ioflupane SPECT 1.0
by Djang, D.S and Janssen, M.J.R and Bohnen, N and Booij, J and Henderson, T.A and Herholz, K and Minoshima, S and Rowe, C.C and Sabri, O and Seibyl, J and Van Berckel, B.N and Wanner, M
The Journal of Nuclear Medicine (1978), ISSN 0161-5505, 2012, Volume 53, Issue 1, pp. 154 - 163
Dopamine Plasma Membrane Transport Proteins - metabolism | Tomography, Emission-Computed, Single-Photon - methods | Humans | Documentation | Image Interpretation, Computer-Assisted | Tomography, Emission-Computed, Single-Photon - standards | Contraindications | Pregnancy | Societies, Medical | Female | Nortropanes | Nuclear Medicine | Research Design
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10. Full Text Intervention versus standard medical treatment in patients with symptomatic occlusion of the internal carotid artery: a randomised oxygen-15 PET study
by Persoon, S and van Berckel, B.N and Bremmer, J.P and Boellaard, R and Algra, A and de Borst, G.J and Lammertsma, A.A and Kappelle, L.J and Klijn, C.J
EJNMMI Research, ISSN 2191-219X, 2013, Volume 3, Issue 1, pp. 1 - 10
The aim of this randomised pilot study was to investigate the haemodynamic effects measured by oxygen-15 positron emission tomography (PET) of interventional... 
Medicine & Public Health | Carotid artery diseases | Orthopedics | Other cerebrovascular disease/stroke | Oncology | Haemodynamics | Nuclear Medicine | Imaging / Radiology | Cardiology | PET | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
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11. Full Text D2 receptor reactivity after total sleep deprivation: Preliminary results in healthy subjects
by Klumpers, Ursula M and Mutluer, K and Veltman, D.J and vanBerckel, B.N and Boellaard, R and Windhorst, B and Hoogendijk, W.J and Lammertsma, A.A
Neuroimage, ISSN 1053-8119, 2008, Volume 41, pp. T128 - T128
  Methods As part of an ongoing study, 5 healthy controls [age range 22-43 years, 3 males] without any psychiatric or neurological condition, and no history of... 
Medical research | Sleep deprivation
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12. Full Text Volume of interest-based [18F]fluorodeoxyglucose PET discriminates MCI converting to Alzheimer's disease from healthy controls. A European Alzheimer's Disease Consortium (EADC) study
by Pagani, M and De Carli, F and Morbelli, S and Öberg, J and Chincarini, A and Frisoni, G.B and Galluzzi, S and Perneczky, R and Drzezga, A and van Berckel, B.N.M and Ossenkoppele, R and Didic, M and Guedj, E and Brugnolo, A and Picco, A and Arnaldi, D and Ferrara, M and Buschiazzo, A and Sambuceti, G and Nobili, F
NeuroImage: Clinical, ISSN 2213-1582, 2015, Volume 7, Issue C, pp. 34 - 42
An emerging issue in neuroimaging is to assess the diagnostic reliability of PET and its application in clinical practice. We aimed at assessing the accuracy... 
FDG-PET | MCI | Discriminant analysis | EADC | Volume of interest | DEMENTIA | MILD COGNITIVE IMPAIRMENT | NEUROIMAGING | NATIONAL INSTITUTE | POSITRON-EMISSION-TOMOGRAPHY | GLUCOSE-METABOLISM | AUTOMATED-ANALYSIS | RECOMMENDATIONS | DIAGNOSTIC GUIDELINES | ASSOCIATION WORKGROUPS | Brain - diagnostic imaging | Humans | Image Interpretation, Computer-Assisted - methods | Middle Aged | Male | Positron-Emission Tomography | Disease Progression | Aged, 80 and over | Female | Fluorodeoxyglucose F18 | Aged | Alzheimer Disease - diagnostic imaging | Cognitive Dysfunction - diagnostic imaging | Radiopharmaceuticals
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13. Full Text P.1.i.006 Further human evidence for striatal dopamine release induced by administration of Δ9-tetrahydrocannabinol (THC)
by Bossong, M.G and Mehta, M.A and Van Berckel, B.N.M and Howes, O.D and Kahn, R.S and Stokes, P.R.A
European Neuropsychopharmacology, ISSN 0924-977X, 2015, Volume 25, pp. S302 - S302
Internal Medicine | Psychiatry
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14. Full Text P.4.032 Neuroinflammation in temporal cortex in schizophrenia patients
by van der Doef, T.F and Yaqub, M and Bossong, M.G and Boellaard, R and Windhorst, A.D and Lammertsma, A.A and Kahn, R.S and van Berckel, B.N.M
European Neuropsychopharmacology, ISSN 0924-977X, 2013, Volume 23, pp. S93 - S94
Internal Medicine | Psychiatry
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