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by Gusarova, Viktoria and O'Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H. Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca A and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas J and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2252 - 11
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient... 
HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | MULTIDISCIPLINARY SCIENCES | MICE | ANGIOPOIETIN-LIKE PROTEIN-4 | LIPOPROTEIN-LIPASE | HAN CHINESE | CHINESE POPULATION | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | Diabetes Mellitus, Type 2 - genetics | Humans | Homeostasis | Male | Diabetes Mellitus, Type 2 - metabolism | Case-Control Studies | Genetic Variation | Diabetes Mellitus, Type 2 - etiology | Female | Lipoprotein Lipase - metabolism | Genetic Association Studies | Mice, Inbred C57BL | Risk Factors | Gene Silencing | Angiopoietin-like 4 Protein - deficiency | Mice, Knockout | Whole Exome Sequencing | Animals | Insulin Resistance - genetics | Angiopoietin-like 4 Protein - metabolism | Heterozygote | Mice | Blood Glucose - metabolism | Amino Acid Substitution | Angiopoietin-like 4 Protein - genetics | Deactivation | Angiopoietin | Diabetes mellitus | Health risks | Risk reduction | Risk | Lipoprotein lipase | Glucose | Lipase | Inactivation | Insulin | Proteins | Confidence intervals | Sensitivity | Nutrient loss | Rodents | Arteriosclerosis | Atherosclerosis | Genetics | Diabetes | Diabetes mellitus (non-insulin dependent) | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Endocrinology and Diabetes
Journal Article
Infection ecology & epidemiology, ISSN 2000-8686, 2016, Volume 6, p. 34094
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, p. e26039
...Author(s): Lotta Berg 1 , C. David Andersson 1 , Elisabet Artursson 2 , Andreas Hornberg 2 , Anna-Karin Tunemalm 2 , Anna Linusson 1 , * , Fredrik Ekstrom 2... 
DOCKING PROGRAMS | TORPEDO-CALIFORNICA | ACTIVE-SITE | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | CRYSTAL-STRUCTURES | SCORING FUNCTIONS | PROTEIN-LIGAND INTERACTIONS | INHIBITORS | DONEPEZIL HYDROCHLORIDE | FLEXIBLE DOCKING | Humans | Cholinesterase Inhibitors - chemistry | Models, Molecular | Cholinesterase Inhibitors - analysis | Crystallography, X-Ray | Acetylcholinesterase - chemistry | Molecular Targeted Therapy | Molecular Dynamics Simulation | Dose-Response Relationship, Drug | Cholinesterase Inhibitors - pharmacology | Inhibitory Concentration 50 | Ligands | Binding Sites | Acetylcholinesterase - metabolism | High-Throughput Screening Assays - methods | Hydrolysis | Enzymes | Nerve gas | Crystals | Acetylcholine | Structure | Alzheimer's disease | Drugs | Molecular structure | Computational neuroscience | High-throughput screening | Amino acids | Nervous system | Acetylcholinesterase | Crystallography | Optimization | Charge distribution | Molecular docking | Genetic algorithms | Proteins | Computational chemistry | Accuracy | Enzymatic activity | Sarin | Chemical bonds | Polarity | Catalysis | Electron density | Coordination compounds | Nerve agents | Pharmaceutical sciences | Crystal structure | Binding | Antidotes | Computer simulation | Neurodegenerative diseases | Research & development--R&D | Lead compounds | Medical screening | Computer programs | Organic chemistry | Chemistry | Side effects | Molecular modelling | Inhibitors | Natural products | Toxins | Alzheimers disease | Cholinergic transmission | Research & development | R&D
Journal Article
Chemistry - A European Journal, ISSN 0947-6539, 02/2016, Volume 22, Issue 8, p. 2672
Molecular recognition events in biological systems are driven by non-covalent interactions between interacting species. Here, we have studied hydrogen bonds of... 
Quantum Theory | Hydrogen Bonding | Models, Molecular | Drug Discovery - methods | Ligands | Acetylcholinesterase - chemistry | Acetylcholinesterase - metabolism
Journal Article
Journal of Computer-Aided Molecular Design, ISSN 0920-654X, 3/2015, Volume 29, Issue 3, pp. 199 - 215
... models in QSAR: a case study on acetylcholinesterase C. David Andersson • J. Mikael Hillgren • Cecilia Lindgren • Weixing Qian • Christine Akfur • Lotta Berg... 
AChE | Correlation | Quantitative structure–activity relationship | SMD | Covariance matrix | Acetylcholinesterase | Statistical molecular design | Chemistry | Physical Chemistry | QSAR | Descriptors | Animal Anatomy / Morphology / Histology | Computer Applications in Chemistry | Quantitative structure-activity relationship | ALZHEIMERS-DISEASE | DOCKING | BIOCHEMISTRY & MOLECULAR BIOLOGY | 3D-QSAR | VALIDATION | VARIABLE SELECTION | TACRINE ANALOGS | 3D QSAR | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | BIOPHYSICS | QUANTITATIVE STRUCTURE-ACTIVITY | INHIBITORS | DERIVATIVES | Chemistry Techniques, Synthetic | Analysis of Variance | Cholinesterase Inhibitors - pharmacology | Cholinesterase Inhibitors - chemistry | Models, Molecular | Cholinesterase Inhibitors - chemical synthesis | Molecular Structure | Structure-Activity Relationship | Acetylcholinesterase - chemistry | Models, Statistical | Acetylcholinesterase - metabolism | Quantitative Structure-Activity Relationship | Case studies | Enzymes | Design and construction | Analysis | Green technology | Models | Statistical analysis | Molecular biology | Index Medicus | Design engineering | Inhibitors | Environmental chemistry | Mathematical models | Biological | Inhibition | Synthetic aperture radar | Statistics in Molecular Modeling | Special Series
Journal Article
NEUROPSYCHIATRIC DISEASE AND TREATMENT, ISSN 1176-6328, 2019, Volume 15, pp. 2049 - 2056
Purpose: To evaluate whether an intervention, targeting deficits in social communication, interaction and restricted activities in children and adolescents... 
INDIVIDUALS | BEHAVIORAL INTERVENTIONS | PSYCHIATRY | SPECTRUM DISORDER | DEFICIT-HYPERACTIVITY DISORDER | RELIABILITY | Down syndrome | PREVALENCE | psychoeducational intervention | intellectual disability | autism | CLINICAL NEUROLOGY | Medicine, Experimental | Medical research | Autism
Journal Article
by Gusarova, Viktoria and O'Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca Andrea and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas John and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper
ISSN 2041-1723, 2018
Journal Article
Journal of Cleaner Production, ISSN 0959-6526, 02/2005, Volume 13, Issue 3, p. 327
Journal Article
Animal (Cambridge, England), ISSN 1751-7311, 02/2016, Volume 10, Issue 2, pp. 294 - 301
Journal Article