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Oncogene, ISSN 0950-9232, 06/2016, Volume 35, Issue 24, pp. 3209 - 3216
Journal Article
Journal of Materials Science, ISSN 0022-2461, 1/2010, Volume 45, Issue 1, pp. 1 - 33
Journal Article
by Newton-Cheh, Christopher and Johnson, Toby and Gateva, Vesela and Tobin, Martin D and Bochud, Murielle and Coin, Lachlan and Najjar, Samer S and Zhao, Jing Hua and Heath, Simon C and Eyheramendy, Susana and Papadakis, Konstantinos and Voight, Benjamin F and Scott, Laura J and Zhang, Feng and Farrall, Martin and Tanaka, Toshiko and Wallace, Chris and Chambers, John C and Khaw, Kay-Tee and Nilsson, Peter and van der Harst, Pim and Polidoro, Silvia and Grobbee, Diederick E and Onland-Moret, N. Charlotte and Bots, Michiel L and Wain, Louise V and Elliott, Katherine S and Teumer, Alexander and Luan, Jian'an and Lucas, Gavin and Kuusisto, Johanna and Burton, Paul R and Hadley, David and McArdle, Wendy L and Brown, Morris and Dominiczak, Anna and Newhouse, Stephen J and Samani, Nilesh J and Webster, John and Zeggini, Eleftheria and Beckmann, Jacques S and Bergmann, Sven and Lim, Noha and Song, Kijoung and Vollenweider, Peter and Waeber, Gerard and Waterworth, Dawn M and Yuan, Xin and Groop, Leif and Orho-Melander, Marju and Allione, Alessana and Di Gregorio, Alessana and Guarrera, Simonetta and Panico, Salvatore and Ricceri, Fulvio and Romanazzi, Valeria and Sacerdote, Carlotta and Vineis, Paolo and Barroso, Ines and Sandhu, Manjinder S and Luben, Robert N and Crawford, Gabriel J and Jousilahti, Pekka and Perola, Markus and Boehnke, Michael and Bonnycastle, Lori L and Collins, Francis S and Jackson, Anne U and Mohlke, Karen L and Stringham, Heather M and Valle, Timo T and Willer, Cristen J and Bergman, Richard N and Morken, Mario A and Doering, Angela and Gieger, Christian and Illig, Thomas and Meitinger, Thomas and Org, Elin and Pfeufer, Arne and Wichmann, H. Erich and Kathiresan, Sekar and Marrugat, Jaume and O'Donnell, Christopher J and Schwartz, Stephen M and Siscovick, David S and Subirana, Isaac and Freimer, Nelson B and Hartikainen, Anna-Liisa and McCarthy, Mark I and O'Reilly, Paul F and Peltonen, Leena and Pouta, Anneli and de Jong, Paul E and Snieder, Harold and van Gilst, Wiek H and Clarke, Robert and Goel, Anuj and Hamsten, Anders and Peden, John F and ... and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Molekylär medicin and Uppsala universitet and Institutionen för medicinska vetenskaper
Nature Genetics, ISSN 1061-4036, 06/2009, Volume 41, Issue 6, pp. 666 - 676
Journal Article
2003, Etudes internationales sur le dix-huitième siècle = International eighteenth-century studies, ISBN 9782745308375, Volume 8, 230
Book
by Gad, Helge and Gad, Helge and Koolmeister, Tobias and Koolmeister, Tobias and Jemth, Ann-Sofie and Jemth, Ann-Sofie and Eshtad, Saeed and Eshtad, Saeed and Jacques, Sylvain A and Jacques, Sylvain A and Ström, Cecilia E and Ström, Cecilia E and Svensson, Linda M and Svensson, Linda M and Schultz, Niklas and Schultz, Niklas and Lundbäck, Thomas and Lundbäck, Thomas and Einarsdottir, Berglind Osk and Einarsdottir, Berglind Osk and Saleh, Aljona and Saleh, Aljona and Göktürk, Camilla and Göktürk, Camilla and Baranczewski, Pawel and Baranczewski, Pawel and Svensson, Richard and Svensson, Richard and Berntsson, Ronnie P-A and Berntsson, Ronnie P.-A and Gustafsson, Robert and Gustafsson, Robert and Strömberg, Kia and Strömberg, Kia and Sanjiv, Kumar and Sanjiv, Kumar and Jacques-Cordonnier, Marie-Caroline and Jacques-Cordonnier, Marie-Caroline and Desroses, Matthieu and Desroses, Matthieu and Gustavsson, Anna-Lena and Gustavsson, Anna-Lena and Olofsson, Roger and Olofsson, Roger and Johansson, Fredrik and Johansson, Fredrik and Homan, Evert J and Homan, Evert J and Loseva, Olga and Loseva, Olga and Bräutigam, Lars and Bräutigam, Lars and Johansson, Lars and Johansson, Lars and Höglund, Andreas and Höglund, Andreas and Hagenkort, Anna and Hagenkort, Anna and Pham, Therese and Pham, Therese and Altun, Mikael and Altun, Mikael and Gaugaz, Fabienne Z and Gaugaz, Fabienne Z and Vikingsson, Svante and Vikingsson, Svante and Evers, Bastiaan and Evers, Bastiaan and Henriksson, Martin and Henriksson, Martin and Vallin, Karl S A and Vallin, Karl S.A and Wallner, Olov A and Wallner, Olov A and Hammarström, Lars G.J and Hammarström, Lars G J and Wiita, Elisee and Wiita, Elisee and Almlöf, Ingrid and Almlöf, Ingrid and Kalderén, Christina and Kalderén, Christina and Axelsson, Hanna and Axelsson, Hanna and Djureinovic, Tatjana and Djureinovic, Tatjana and Puigvert, Jordi Carreras and Puigvert, Jordi Carreras and Häggblad, Maria and Häggblad, Maria and Jeppsson, Fredrik and Jeppsson, Fredrik and Martens, Ulf and Martens, Ulf and Lundin, Cecilia and Lundin, Cecilia and Lundgren, B and Lundgren, Bo and Granelli, Ingrid and Granelli, Ingrid and ... and Institutionen för medicin och hälsa and Avdelningen för läkemedelsforskning and Linköpings universitet and Hälsouniversitetet
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 7495, pp. 215 - 221
Cancers have dysfunctional redox regulation resulting in reactive oxygen species production, damaging both DNA and free dNTPs. The MTH1 protein sanitizes... 
TARGET | CELLS | OXIDATIVE STRESS | REPAIR | HMTH1 | PROTEIN | MULTIDISCIPLINARY SCIENCES | DNA-SYNTHESIS | MUTAGENIC SUBSTRATE | CELLULAR SENESCENCE | 8-OXOGUANINE | Neoplasms - metabolism | Humans | Molecular Conformation | Male | Molecular Targeted Therapy | Pyrimidines - chemistry | Pyrophosphatases - antagonists & inhibitors | Enzyme Inhibitors - pharmacokinetics | Enzyme Inhibitors - chemistry | DNA Repair Enzymes - metabolism | Oxidation-Reduction - drug effects | Female | Deoxyguanine Nucleotides - metabolism | Cell Death - drug effects | DNA Repair Enzymes - antagonists & inhibitors | DNA Repair Enzymes - chemistry | Phosphoric Monoester Hydrolases - antagonists & inhibitors | Cell Survival - drug effects | Catalytic Domain | Reproducibility of Results | Crystallization | Enzyme Inhibitors - pharmacology | Models, Molecular | Pyrimidines - pharmacology | Nucleotides - metabolism | Enzyme Inhibitors - therapeutic use | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Pyrimidines - therapeutic use | Pyrimidines - pharmacokinetics | Mice | DNA Damage | Neoplasms - pathology | Phosphoric Monoester Hydrolases - metabolism | Phosphoric Monoester Hydrolases - chemistry | Prevention | Deoxyribonucleotides | DNA damage | Cancer cells | Physiological aspects | Research | Binding proteins | Cancer | Cytotoxicity | Kinases | Cancer therapies | Defects | Proteins | Genotype & phenotype | Mutagenesis | Rodents | Cell cycle | Mutation | Deoxyribonucleic acid--DNA | Tumors | Apoptosis | Index Medicus | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
Journal Article
SAE technical paper series, Volume 700756.
This paper is a brief review of the background of space station design effort from the time manned space flight was initiated to the present. The existing... 
Spacecraft
eJournal
The Pharmacogenomics Journal, ISSN 1470-269X, 02/2011, Volume 11, Issue 1, pp. 61 - 71
Irinotecan and 5-fluorouracil (5-FU) are used to treat metastatic colorectal cancer. Irinotecan's active metabolite is inactivated by... 
P-glycoprotein | camptothecin/analogs and derivatives | thymidylate synthase | glucuronosyltransferase | methylenetetrahydrofolate reductase (NADPH2) | fluorouracil | UGT1A1-ASTERISK-28 POLYMORPHISM | UDP-GLUCURONOSYLTRANSFERASE GENE | UGT1A1 GENE | GENOTYPE | PROMOTER POLYMORPHISM | PHARMACOGENETIC ANALYSIS | CELL LUNG-CANCER | GILBERTS-SYNDROME | HAPLOTYPE ANALYSIS | GENETICS & HEREDITY | PHARMACOLOGY & PHARMACY | Haplotypes | Colorectal Neoplasms - genetics | Humans | Middle Aged | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Methylenetetrahydrofolate Reductase (NADPH2) - metabolism | Glucuronosyltransferase - genetics | Fluorouracil - administration & dosage | Fluorouracil - adverse effects | Methylenetetrahydrofolate Reductase (NADPH2) - genetics | Colorectal Neoplasms - drug therapy | Camptothecin - administration & dosage | Female | Retrospective Studies | Neutropenia - chemically induced | Neutropenia - genetics | Camptothecin - analogs & derivatives | Camptothecin - pharmacokinetics | Camptothecin - adverse effects | Colorectal Neoplasms - enzymology | Colorectal Neoplasms - blood | Thymidylate Synthase - metabolism | Genotype | Survival Rate | Treatment Outcome | Thymidylate Synthase - genetics | Disease-Free Survival | Glucuronosyltransferase - metabolism | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Thymidylate Synthase - antagonists & inhibitors | Fluorouracil - pharmacokinetics | Dosage and administration | Research | Drug therapy | Colorectal cancer | Fluorouracil | Index Medicus | camptothecin | analogs and derivatives | Original | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICIN | MEDICINE
Journal Article