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Statistics in Biopharmaceutical Research, ISSN 1946-6315, 03/2019, pp. 1 - 17
Journal Article
Journal Article
Pharmaceutical Statistics, ISSN 1539-1604, 11/2015, Volume 14, Issue 6, pp. 433 - 447
Journal Article
Annals of Statistics, ISSN 0090-5364, 10/2017, Volume 45, Issue 5, pp. 2102 - 2132
A common problem in Phase II clinical trials is the comparison of dose response curves corresponding to different treatment groups. If the effect of the dose... 
Different treatment groups | D-optimal design | Loewner ordering | Nonlinear regression | Admissible design | nonlinear regression | TRIALS | EFFICACY | STATISTICS & PROBABILITY | POLYNOMIAL REGRESSION | ROBUST OPTIMAL DESIGNS | EQUIVALENCE | E-MAX MODEL | DISCRIMINATION | LOCALLY OPTIMAL DESIGNS | LA GARZA PHENOMENON | different treatment groups | EMAX
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 01/2005, Volume 45, Issue 2, pp. 252 - 259
Journal Article
European Journal of Heart Failure, ISSN 1388-9842, 05/2015, Volume 17, Issue 5, pp. 527 - 533
Journal Article
1993, Acta Universitatis Upsaliensis. Studia statistica Upsaliensia, ISBN 9155431623, Volume 1
Dissertation
06/2018
Biomarker measurements can be relatively easy and quick to obtain and they are useful to investigate whether a compound works as intended on a mechanistic,... 
Statistics - Methodology
Journal Article
Journal Article
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 01/2005, Volume 45, Issue 2, pp. 252 - 259
The goal of this study was to explore the question: what resting heart rate (HR) should one aim for when treating patients with heart failure with a... 
Heart failure | Medical colleges | Care and treatment | Heart beat | Cardiac patients
Journal Article
03/2016
A common problem in Phase II clinical trials is the comparison of dose response curves corresponding to different treatment groups. If the effect of the dose... 
Journal Article
06/2019
The present invention relates to canakinumab for use in reducing the risk of or preventing recurrent cardiovascular (CV) events in a patient with elevated... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
02/2019
The present invention relates to canakinumab for use in reducing the risk of or preventing recurrent cardiovascular (CV) events in a patient with elevated... 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
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