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Neuropsychopharmacology, ISSN 0893-133X, 08/2013, Volume 38, Issue 9, pp. 1724 - 1736
Hypocretin/orexin signaling is critically involved in relapse to drug-seeking behaviors. In this study, we investigated the involvement of the hypocretin... 
hypocretin | PKC | cue | nicotine | reinstatement | glutamate | PROTEIN-KINASE-C | NMDA RECEPTORS | PSYCHIATRY | COCAINE-SEEKING | SYNAPTIC PLASTICITY | REWARD | NEUROSCIENCES | ADDICTION | GLUTAMATE RECEPTORS | OREXIN/HYPOCRETIN | AMPA RECEPTORS | ALCOHOL-SEEKING | PHARMACOLOGY & PHARMACY | Benzoxazoles - pharmacology | Nicotine - administration & dosage | Phosphorylation | Nucleus Accumbens - metabolism | Receptors, N-Methyl-D-Aspartate - metabolism | Conditioning, Operant - physiology | Extinction, Psychological - drug effects | Male | Nicotine - pharmacology | Self Administration | Isoquinolines - pharmacology | Conditioning, Operant - drug effects | Orexin Receptors - physiology | Piperidines - pharmacology | Urea - analogs & derivatives | Neurons - physiology | p38 Mitogen-Activated Protein Kinases - metabolism | Hypothalamus - drug effects | Neurons - drug effects | Extinction, Psychological - physiology | Nicotinic Agonists - pharmacology | Receptors, AMPA - metabolism | Cues | Orexin Receptor Antagonists | Piperidines - administration & dosage | Microinjections | Hypothalamus - physiology | Drug-Seeking Behavior - physiology | Drug-Seeking Behavior - drug effects | Nerve Tissue Proteins - metabolism | Nicotinic Agonists - administration & dosage | Animals | Signal Transduction - drug effects | Prefrontal Cortex - metabolism | Signal Transduction - physiology | Mice | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Urea - pharmacology | Cortex (prefrontal) | Addicció | Farmacologia | Nicotina | Behavioral Science | Addiction & Substance Abuse | Animal models | Neuropeptides | Original | Hypocretin | Nicotine
Journal Article
Psychopharmacology, ISSN 0033-3158, 8/2002, Volume 163, Issue 1, pp. 111 - 117
Rationale. Recent studies have shown that several pharmacological actions induced by cannabinoids, including antinociception and reward, involve the... 
Δ9-Tetrahydrocannabinol CB1 cannabinoid receptor Opioid system Anxiety Light-dark box | Neurosciences | Biomedicine | Pharmacology/Toxicology | Psychiatry | Anxiety | Opioid system | cannabinoid receptor | Light-dark box | Tetrahydrocannabinol
Journal Article
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ISSN 0893-133X, 2014, Volume 39, Issue 12, pp. 2732 - 2741
Journal Article
Psychopharmacology, ISSN 0033-3158, 12/2019
Cannabis use is typically initiated during adolescence, and different studies suggest that adolescent cannabinoid exposure may increase the risk for drug... 
Journal Article
Journal Article
Trends in Neurosciences, ISSN 0166-2236, 2015, Volume 38, Issue 9, pp. 550 - 559
Journal Article
British journal of pharmacology, ISSN 0007-1188, 04/2016, Volume 173, Issue 8, p. 1381
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2014, Volume 75, Issue 6, pp. 499 - 507
Background Cannabis is the most widely used illicit drug in the world. Although there is a high prevalence of users who seek treatment for cannabis dependence,... 
Psychiatry | knockout | reward | WIN55 | hypocretin | Cannabinoid | dopamine | 212-2 | SYSTEM | ACTIVATION | HYPOTHALAMIC OREXIN/HYPOCRETIN NEURONS | NICOTINE | INVOLVEMENT | COCAINE | OREXIN NEURONS | NEUROSCIENCES | VENTRAL TEGMENTAL AREA | WIN55,212-2 | ALCOHOL-SEEKING | EXPRESSION | Marijuana Abuse - drug therapy | Benzoxazoles - pharmacology | Hypothalamic Area, Lateral - metabolism | Nucleus Accumbens - metabolism | Conditioning, Operant - physiology | Male | Cannabinoid Receptor Agonists - pharmacology | Molecular Targeted Therapy | Self Administration | Conditioning, Operant - drug effects | Urea - analogs & derivatives | Orexin Receptors - genetics | Dronabinol - pharmacology | Dopamine - metabolism | Orexin Receptor Antagonists | Orexin Receptors - metabolism | Benzoxazines - administration & dosage | Morpholines - administration & dosage | Proto-Oncogene Proteins c-fos - metabolism | Morpholines - pharmacology | Marijuana Abuse - metabolism | Cannabinoid Receptor Agonists - administration & dosage | Cannabinoids - pharmacology | Mice, Knockout | Naphthalenes - pharmacology | Reinforcement Schedule | Animals | Naphthalenes - administration & dosage | Benzoxazines - pharmacology | Orexin Receptors - agonists | Mice | Reward | Nucleus Accumbens - drug effects | Urea - pharmacology | Marijuana | Cannabinoides
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 11/2018, Volume 157, pp. 43 - 50
A growing body of evidence suggests the existence of biochemical and functional interactions between the endocannabinoid and orexin systems. Cannabinoid and... 
Nociception | Heterodimers | Reward | Cannabinoid | Orexin | Feeding | LATERAL HYPOTHALAMUS | FOOD-INTAKE | PLACE PREFERENCE | ENDOCANNABINOID SYSTEM | PERIAQUEDUCTAL GRAY-MATTER | VENTRAL TEGMENTAL AREA | PHARMACOLOGY & PHARMACY | RAT-BRAIN | HYPOCRETIN/OREXIN NEURONS | CHEMICAL-STIMULATION | CB1 RECEPTORS | Glycerin | Glycerol | Efectes fisiològics | Cannabinoides
Journal Article