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Membranes, ISSN 2077-0375, 08/2014, Volume 4, Issue 3, pp. 424 - 446
The EGFR- or ErbB-family of receptor tyrosine kinases consists of EGFR/ErbB1, ErbB2/HER2, ErbB3/HER3 and ErbB4/HER4. Receptor activation and downstream... 
Hsp90 | Endocytosis | Ubiquitination | ErbB2 | Antibodies | Clathrin-coated pits | Nuclear trafficking | HER2 | clathrin-coated pits | ubiquitination | nuclear trafficking | endocytosis | antibodies
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2009, Volume 361, Issue 1, pp. 32 - 39
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0127228
Journal Article
Experimental Cell Research, ISSN 0014-4827, 09/2019, Volume 382, Issue 2, p. 111473
ErbB3, which belongs to the epidermal growth factor receptor (EGFR) or ErbB family of receptor tyrosine kinases, is involved in progression of several human... 
Receptor internalization | Endosomal sorting | Phorbol 12-myristate 13-acetate (PMA) | Receptor recycling | ErbB3 | Protein kinase C (PKC) | MECHANISM | SPECIFICITY | PHOSPHORYLATION | TYROSINE KINASE | ENDOCYTOSIS | CELL BIOLOGY | SEQUESTRATION | GROWTH-FACTOR RECEPTOR | INTERNALIZATION | ONCOLOGY | SELECTIVE INHIBITORS | EGF RECEPTOR
Journal Article
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 12/2017, Volume 1864, Issue 12, pp. 2241 - 2252
The ErbB family of receptor tyrosine kinases mediates activation of a wide network of signaling pathways. ErbB3 has weak kinase activity, but its six docking... 
Ubiquitin | ERAD | Hrs | Endosomal sorting | Endocytosis | ErbB3 | INDUCED DOWN-REGULATION | PROTEASOMAL ACTIVITY | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CLATHRIN-COATED PITS | PLASMA-MEMBRANE | CELL BIOLOGY | GROWTH-FACTOR RECEPTOR | ENDOPLASMIC-RETICULUM | MEMBRANE-PROTEINS | EGF RECEPTOR | E3 UBIQUITIN LIGASE | Cells
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 01/2019, Volume 139, Issue 1, pp. 81 - 90
Although inflammation has traditionally been considered a response to either exogenous pathogen-associated signals or endogenous signals of cell damage, other... 
CELL-VOLUME REGULATION | IFN-GAMMA | INFLAMMATION | DUAL FUNCTION | ALPHA | INTERLEUKIN-33 | EXPRESSION | DERMATOLOGY
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 06/2016, Volume 1863, Issue 6, pp. 1179 - 1188
In contrast to other members of the EGF receptor family, ErbB3 is constitutively internalized in a clathrin-dependent manner. Previous studies have shown that... 
Ubiquitin | Endocytosis | Clathrin | Epsin | ErbB3 | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | EGF RECEPTORS | CANCER | CELL BIOLOGY | UBIQUITINATION | GROWTH-FACTOR RECEPTOR | MEDIATED ENDOCYTOSIS | VESICLE ENDOCYTOSIS | DEGRADATION | COATED PITS | Epidermal growth factor | Analysis
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 08/2004, Volume 15, Issue 8, pp. 3591 - 3604
Ligand binding causes the EGF receptor (EGFR) to become ubiquitinated by Cbl upon association with the adaptor protein Grb2. We have investigated the role of... 
GROWTH-FACTOR RECEPTOR | PROTEIN INTERACTIONS | INTERNALIZATION | TYROSINE PHOSPHORYLATION | C-CBL | MEDIATED ENDOCYTOSIS | DOWN-REGULATION | GUANINE-NUCLEOTIDE EXCHANGE | RING FINGER | PLASMA-MEMBRANE | CELL BIOLOGY
Journal Article