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1. Full Text Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets
by Sander Herfst and Eefje J. A. Schrauwen and Martin Linster and Salin Chutinimitkul and Emmie de Wit and Vincent J. Munster and Erin M. Sorrell and Theo M. Bestebroer and David F. Burke and Derek J. Smith and Guus F. Rimmelzwaan and Albert D. M. E. Osterhaus and Ron A. M. Fouchier
Science (American Association for the Advancement of Science), ISSN 0036-8075, 6/2012, Volume 336, Issue 6088, pp. 1534 - 1541
Receptors | Inoculation | Experimental infection | Disease transmission | Pandemics | REPORTS | Viruses | Orthomyxoviridae | Ferrets | Genetic mutation | Amino acid substitution | particle size | Influenza virus A H5N1 | antiviral resistance | hemagglutination test | virus replication | virus transmission | site directed mutagenesis | virus particle | Influenza virus A | animal experiment | nose smear | review | animal tissue | virus isolation | DNA modification | nonhuman | sequence analysis | amino acid substitution | priority journal | ferret | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immune Sera | Reassortant Viruses - pathogenicity | Influenza A Virus, H5N1 Subtype - physiology | Poultry | Receptors, Virus - metabolism | Air Microbiology | Humans | Virulence | Molecular Sequence Data | Influenza A Virus, H5N1 Subtype - genetics | Virus Shedding | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Respiratory System - virology | Female | Influenza, Human - virology | Oseltamivir - pharmacology | Disease Models, Animal | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Reverse Genetics | Antiviral Agents - pharmacology | Mutagenesis, Site-Directed | RNA Replicase - genetics | Viral Proteins - chemistry | Sialic Acids - metabolism | Viral Proteins - genetics | Influenza, Human - epidemiology | Containment of Biohazards | Influenza A Virus, H5N1 Subtype - drug effects | Influenza in Birds - epidemiology | Influenza, Human - transmission | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Animals | Orthomyxoviridae Infections - transmission | Virus Replication | RNA Replicase - chemistry | Influenza in Birds - virology | Influenza A Virus, H5N1 Subtype - pathogenicity | Mutation | Serial Passage | Orthomyxoviridae Infections - virology | Amino Acid Substitution | Avian influenza | Diseases and pests | Physiological aspects | Development and progression | Research | Animal diseases | Amino acids | Avian flu | Small mammals | Index Medicus | Polymerase | Human | Proteins | Influenza | Droplets | Genetic modification
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2. Full Text Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution
by Björn F. Koel and David F. Burke and Theo M. Bestebroer and Stefan van der Vliet and Gerben C. M. Zondag and Gaby Vervaet and Eugene Skepner and Nicola S. Lewis and Monique I. J. Spronken and Colin A. Russell and Mikhail Y. Eropkin and Aeron C. Hurt and Ian G. Barr and Jan C. de Jong and Guus F. Rimmelzwaan and Albert D. M. E. Osterhaus and Ron A. M. Fouchier and Derek J. Smith
Science (American Association for the Advancement of Science), ISSN 0036-8075, 11/2013, Volume 342, Issue 6161, pp. 976 - 979
Phenotypes | Receptors | Reactivity | Influenza | REPORTS | Antibodies | Viruses | Amino acids | Orthomyxoviridae | Ferrets | Amino acid substitution | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antigens, Viral - immunology | Humans | Amino Acid Substitution - immunology | Amino Acid Substitution - genetics | Antigens, Viral - genetics | Binding Sites - genetics | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Influenza A Virus, H3N2 Subtype - genetics | Mutation | Influenza A Virus, H3N2 Subtype - immunology | Evolution, Molecular | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Influenza viruses | Physiological aspects | Host-parasite relationships | Research | Health aspects | Binding sites (Biochemistry) | Antigens | Evolutionary biology | Neurons | Binding sites | Index Medicus | Immune systems | Evolution | Drift
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3. Full Text The Multibasic Cleavage Site in H5N1 Virus Is Critical for Systemic Spread along the Olfactory and Hematogenous Routes in Ferrets
by Eefje J. A. Schrauwen and Sander Herfst and Lonneke M. Leijten and Peter van Run and Theo M. Bestebroer and Martin Linster and Rogier Bodewes and Joost H. C. M. Kreijtz and Guus F. Rimmelzwaan and Albert D. M. E. Osterhaus and Ron A. M. Fouchier and Thijs Kuiken and Debby van Riel
Journal of Virology, ISSN 0022-538X, 04/2012, Volume 86, Issue 7, pp. 3975 - 3984
hematopoietic system | virus replication | virus transmission | in vitro study | inoculation | virus detection | pancreas | olfactory epithelium | priority journal | animal model | respiratory tract infection | invasive procedure | Influenza virus A H5N1 | olfactory bulb | liver | animal cell | olfactory system | multibasic cleavage site | animal experiment | article | disease association | heart | controlled study | cerebrospinal fluid | colon | DNA cleavage | nonhuman | wild type | ferret | Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Cell Line | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Influenza, Human - pathology | Humans | Virulence | Ferrets - blood | Olfactory Pathways - virology | Influenza, Human - blood | Influenza A Virus, H5N1 Subtype - genetics | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Amino Acid Motifs | Ferrets - virology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Animals | Virus Replication | Blood - virology | Influenza A Virus, H5N1 Subtype - chemistry | Female | Influenza A Virus, H5N1 Subtype - pathogenicity | Influenza, Human - virology | Protein Processing, Post-Translational | Influenza A Virus, H5N1 Subtype - metabolism | Olfactory Pathways - pathology | Disease Models, Animal | Index Medicus | Pathogenesis and Immunity
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4. Full Text Adenosine Deaminase Acts as a Natural Antagonist for Dipeptidyl Peptidase 4-Mediated Entry of the Middle East Respiratory Syndrome Coronavirus
by V. Stalin Raj and Saskia L. Smits and Lisette B. Provacia and Judith M. A. van den Brand and Lidewij Wiersma and Werner J. D. Ouwendijk and Theo M. Bestebroer and Monique I. Spronken and Geert van Amerongen and Peter J. M. Rottier and Ron A. M. Fouchier and Berend Jan Bosch and Albert D.M.E. Osterhaus and Bart L. Haagmans
Journal of Virology, ISSN 0022-538X, 02/2014, Volume 88, Issue 3, pp. 1834 - 1838
Life Sciences & Biomedicine | Science & Technology | Virology | Amino Acid Sequence | Dipeptidyl Peptidase 4 - metabolism | Spike Glycoprotein, Coronavirus - genetics | Spike Glycoprotein, Coronavirus - metabolism | Adenosine Deaminase - genetics | Adenosine Deaminase - metabolism | Receptors, Virus - metabolism | Dipeptidyl Peptidase 4 - chemistry | Humans | Coronaviridae Infections - virology | Molecular Sequence Data | Dipeptidyl Peptidase 4 - genetics | Receptors, Virus - genetics | Ferrets | Virus Internalization | Sequence Alignment | Animals | Receptors, Virus - chemistry | Protein Binding | Coronaviridae - physiology | Coronaviridae Infections - enzymology | Coronaviridae - genetics | Disease Models, Animal | Index Medicus | Virus-Cell Interactions
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5. Full Text Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
by Zaki, Ali M and van Boheemen, Sander and Bestebroer, Theo M and Osterhaus, Albert D.M.E and Fouchier, Ron A.M
The New England journal of medicine, ISSN 0028-4793, 11/2012, Volume 367, Issue 19, pp. 1814 - 1820
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Genome, Viral | Coronavirus - classification | Blood Urea Nitrogen | Humans | Middle Aged | DNA, Viral - analysis | Male | Sputum - virology | Lung - diagnostic imaging | Phylogeny | Reverse Transcriptase Polymerase Chain Reaction | Renal Insufficiency - etiology | Blood Cell Count | Radiography | Pneumonia, Viral - diagnostic imaging | Pneumonia, Viral - complications | Fatal Outcome | Coronavirus - genetics | Creatinine - blood | Pneumonia, Viral - virology | Virus Replication - physiology | Coronavirus - physiology | Coronavirus - isolation & purification | Case studies | Pneumonia | Care and treatment | Bacterial pneumonia | Severe acute respiratory syndrome | Causes of | Coronaviruses | Diagnosis | Health aspects | Cell culture | Enzymes | Disease | Diagnostic tests | Viruses | Outbreaks | Infections | Genomes | RNA polymerase | Patients | Hospitals | Health surveillance | Influenza | Sputum | Renal failure | Index Medicus | Abridged Index Medicus
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6. Full Text A compensatory mutagenesis study of a conserved hairpin in the M gene segment of influenza A virus shows its role in virus replication
by Spronken, M. I and van de Sandt, C. E and de Jongh, E. P and Vuong, O and van der Vliet, S and Bestebroer, T. M and Olsthoorn, R. C. L and Rimmelzwaan, G. F and Fouchier, R.A. M and Gultyaev, A. P
RNA biology, ISSN 1547-6286, 11/2017, Volume 14, Issue 11, pp. 1606 - 1616
Compensatory mutagenesis | negative sense RNA virus | RNA structure | influenza A virus | RNA splicing | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Viral Matrix Proteins - genetics | Alternative Splicing | Humans | Influenza A virus - genetics | Structure-Activity Relationship | RNA, Messenger - metabolism | RNA, Viral - genetics | HEK293 Cells | Madin Darby Canine Kidney Cells | Conserved Sequence | Viral Matrix Proteins - metabolism | RNA, Viral - metabolism | Nucleic Acid Conformation | Inverted Repeat Sequences | Influenza A virus - growth & development | RNA, Messenger - genetics | Virus Assembly | Animals | Influenza A virus - metabolism | RNA, Viral - chemistry | Base Pairing | Mutagenesis | Viral Matrix Proteins - chemistry | Virus Replication | Dogs | RNA, Messenger - chemistry | Index Medicus
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7. Full Text Pathogenesis and Transmission of Swine-Origin 2009 A(H1N1) Influenza Virus in Ferrets
by Vincent J. Munster and Emmie de Wit and Judith M. A. van den Brand and Sander Herfst and Eefje J. A. Schrauwen and Theo M. Bestebroer and David van de Vijver and Charles A. Boucher and Marion Koopmans and Guus F. Rimmelzwaan and Thijs Kuiken and Albert D. M. E. Osterhaus and Ron A. M. Fouchier
Science (American Association for the Advancement of Science), ISSN 0036-8075, 7/2009, Volume 325, Issue 5939, pp. 481 - 483
Inoculation | Throat | Disease transmission | Lungs | Aerosols | Viruses | Orthomyxoviridae | Reports | Infections | Ferrets | Trachea | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Viral diseases of the respiratory system and ent viral diseases | Infectious diseases | Medical sciences | Human viral diseases | Viral diseases | Bronchi - virology | Influenza, Human - pathology | Humans | Orthomyxoviridae Infections - pathology | Child, Preschool | Influenza A Virus, H1N1 Subtype - pathogenicity | Virus Shedding | Influenza, Human - transmission | Trachea - virology | Respiratory System - virology | Animals | Orthomyxoviridae Infections - transmission | Virus Replication | Female | Influenza, Human - virology | Seasons | Orthomyxoviridae Infections - virology | Swine - virology | Disease Models, Animal | Development and progression | Genetic aspects | Swine influenza | Animal diseases | Pathology | Mammals | Swine flu | Index Medicus
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8. Full Text SARS-CoV-2 is transmitted via contact and via the air between ferrets
by Richard, Mathilde and Kok, A and Meulder, Dennis and Bestebroer, Theo and Lamers, Mart M and Okba, Nisreen and Fentener van Vlissingen, M and Rockx, Barry and Haagmans, Bart and Koopmans, Marion and Fouchier, Ron and Herfst, Sander
Nature communications, ISSN 2041-1723, 07/2020, Volume 11, Issue 1, pp. 3496 - 3496
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Pandemics | Betacoronavirus - isolation & purification | Genome, Viral - genetics | Humans | Virus Shedding | Ferrets | Antibodies, Viral - blood | Rectum - virology | Betacoronavirus - immunology | COVID-19 | Coronavirus Infections - transmission | Pneumonia, Viral - transmission | Respiratory System - virology | SARS-CoV-2 | Animals | Sequence Analysis, RNA | Coronavirus Infections - virology | Betacoronavirus - physiology | Betacoronavirus - genetics | Pneumonia, Viral - virology | Disease Models, Animal | Severe acute respiratory syndrome coronavirus 2 | Animal models | Severe acute respiratory syndrome | Viral diseases | Aerosols | Viruses | Infections | Droplets | Coronaviruses | Disease control | Information dissemination | Index Medicus
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9. Full Text Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans
by Boheemen, Sander and Graaf, Marieke and Lauber, Chris and Bestebroer, Theo and Raj, Stalin and Zaki, Ali and Osterhaus, Albert and Haagmans, Bart and Gorbalenya, Alexander and Snijder, Eric and Fouchier, Ron
mBio, ISSN 2161-2129, 11/2012, Volume 3, Issue 6
Life Sciences & Biomedicine | Microbiology | Science & Technology | Genome, Viral | Coronavirus - classification | Humans | Open Reading Frames | Molecular Sequence Data | Phylogeny | Sequence Analysis, DNA | Sequence Homology, Amino Acid | Netherlands | RNA, Viral - genetics | Gene Expression Regulation, Viral | Respiratory Distress Syndrome, Adult - virology | Genes, Viral | Coronavirus - genetics | Pneumonia, Viral - virology | Cluster Analysis | Coronavirus - isolation & purification | Index Medicus
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10. Full Text An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels
by Haagmans, Bart L and van den Brand, Judith M A and Raj, V Stalin and Volz, Asisa and Wohlsein, Peter and Smits, Saskia L and Schipper, Debby and Bestebroer, Theo M and Okba, Nisreen and Fux, Robert and Bensaid, Albert and Solanes Foz, David and Kuiken, Thijs and Baumgärtner, Wolfgang and Segalés, Joaquim and Sutter, Gerd and Osterhaus, Albert D M E
Science (American Association for the Advancement of Science), ISSN 0036-8075, 01/2016, Volume 351, Issue 6268, pp. 77 - 81
Antibodies, Neutralizing | Coronavirus Infections | Camelus | Humans | Virus Shedding | Antibodies, Viral | Journal Article | Middle East Respiratory Syndrome Coronavirus | Spike Glycoprotein, Coronavirus | Vaccinia virus | Animals | Disease Outbreaks | Research Support, Non-U.S. Gov't | RNA, Viral | Viral Vaccines | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Coronavirus Infections - prevention & control | Spike Glycoprotein, Coronavirus - genetics | Virus Shedding - immunology | Antibodies, Viral - blood | Vaccinia virus - genetics | Vaccinia virus - immunology | Camelus - virology | Antibodies, Neutralizing - immunology | Coronavirus Infections - veterinary | Antibodies, Viral - immunology | Disease Outbreaks - prevention & control | RNA, Viral - immunology | Spike Glycoprotein, Coronavirus - immunology | Viral Vaccines - immunology | Antibodies, Neutralizing - blood | Middle East Respiratory Syndrome Coronavirus - physiology | Health aspects | Vaccines | Dosage and administration | Viral vaccines | Camels | Viruses | Respiratory diseases | Hygiene | Index Medicus | Reduction | Excretion | Transmissions (automotive) | Disorders
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