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1. Predicting Risk for Adult-Onset Sudden Cardiac Death in the Population
by Bezzina, Connie R and Walsh, Roddy and Lahrouchi, Najim
Journal of the American College of Cardiology, ISSN 0735-1097, 11/2019, Volume 74, Issue 21, pp. 2635 - 2637
genomic medicine | sudden cardiac death | next-generation sequencing | presymptomatic screening | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Adult | High-Throughput Nucleotide Sequencing | Death, Sudden, Cardiac | Humans | Cardiac arrhythmia | Cardiomyopathy | Genomics | Mortality | Cardiovascular disease | Genomes | Genotype & phenotype | Defibrillators | Coronary vessels | Population | Aortic dissection | Health risk assessment | Age
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2. Full Text Genetics of congenital heart disease: the contribution of the noncoding regulatory genome
by Postma, Alex V and Bezzina, Connie R and Christoffels, Vincent M
Journal of human genetics, ISSN 1434-5161, 2016, Volume 61, Issue 1, pp. 13 - 19
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Exome | Inheritance Patterns | Heart Defects, Congenital - genetics | Genome-Wide Association Study | Enhancer Elements, Genetic | Gene Expression Regulation, Developmental | Humans | Regulatory Sequences, Nucleic Acid | High-Throughput Nucleotide Sequencing | Mutation | Genome, Human | Index Medicus
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3. Full Text A Mutation in CALM1 Encoding Calmodulin in Familial Idiopathic Ventricular Fibrillation in Childhood and Adolescence
by Marsman, Roos F and Barc, Julien and Beekman, Leander and Alders, Marielle and Dooijes, Dennis and van den Wijngaard, Arthur and Ratbi, Ilham and Sefiani, Abdelaziz and Bhuiyan, Zahurul A and Wilde, Arthur A.M and Bezzina, Connie R
Journal of the American College of Cardiology, ISSN 0735-1097, 01/2014, Volume 63, Issue 3, pp. 259 - 266
ventricular arrhythmia | exome sequencing | genetics | calmodulin | idiopathic ventricular fibrillation | idiopathic ventricular fibrillation | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Calmodulin - genetics | Genetic Predisposition to Disease | Ventricular Fibrillation - metabolism | Humans | Male | DNA - genetics | Monomeric Clathrin Assembly Proteins - genetics | DNA Mutational Analysis | Pedigree | Adolescent | Electrocardiography | Ventricular Fibrillation - genetics | Ventricular Fibrillation - physiopathology | Female | Mutation | Child | Cardiac arrhythmia | Heart attacks | Genes
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4. Full Text Common genetic variation and risk for sudden cardiac death in acquired cardiac disease
by Bezzina, Connie R., PhD
Heart rhythm, ISSN 1547-5271, 2014, Volume 11, Issue 4, pp. 653 - 654
Cardiovascular | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Coronary Disease - complications | Humans | Polymorphism, Single Nucleotide - genetics | Female | Heart Failure - genetics | Male | Death, Sudden, Cardiac - etiology | Calsequestrin - genetics | Heart | Genetic aspects | Index Medicus
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5. Full Text Genetics of sudden cardiac death caused by ventricular arrhythmias
by Marsman, Roos F and Tan, Hanno L and Bezzina, Connie R
Nature reviews cardiology, ISSN 1759-5010, 2014, Volume 11, Issue 2, pp. 96 - 111
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Phenotype | Tachycardia, Ventricular - complications | Tachycardia, Ventricular - mortality | Global Health | Humans | Risk Factors | Tachycardia, Ventricular - genetics | Survival Rate | Death, Sudden, Cardiac - etiology | Genetic Techniques | Cause of Death | Causes of | Complications and side effects | Genetic aspects | Arrhythmia | Cardiac arrest | Index Medicus
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6. Full Text Patch-Clamp Recording from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Improving Action Potential Characteristics through Dynamic Clamp
by Verkerk, Arie O and Veerman, Christiaan C and Zegers, Jan G and Mengarelli, Isabella and Bezzina, Connie R and Wilders, Ronald
International journal of molecular sciences, ISSN 1422-0067, 2017, Volume 18, Issue 9, p. 1873
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Potassium - metabolism | Tretinoin - administration & dosage | Action Potentials - genetics | Induced Pluripotent Stem Cells - drug effects | Induced Pluripotent Stem Cells - physiology | Humans | Potassium Channels, Inwardly Rectifying | Arrhythmias, Cardiac - physiopathology | Action Potentials - physiology | Arrhythmias, Cardiac - drug therapy | Patch-Clamp Techniques | Heart Ventricles - physiopathology | Cell Differentiation - drug effects | Myocytes, Cardiac - physiology | Atrial Function - genetics | Cell Differentiation - physiology | Arrhythmias, Cardiac - genetics | Cardiac arrhythmia | Computer simulation | Cardiomyocytes | Action potential | Injection | Stem cells | Mathematical models | Membrane potential | Ventricle | Retinoic acid | Heart diseases | Pluripotency | Membrane currents | Index Medicus | cardiomyocytes | inward rectifier potassium current | retinoic acid | differentiation | electro-physiology | induced pluripotent stem cells | computer simulations | perforated patch-clamp
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7. Full Text Epidemiology of inherited arrhythmias
by Offerhaus, Joost A and Bezzina, Connie R and Wilde, Arthur A. M
Nature reviews cardiology, ISSN 1759-5002, 2020, Volume 17, Issue 4, pp. 205 - 215
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Arrhythmias, Cardiac - epidemiology | Prevalence | Humans | Female | Male | Arrhythmias, Cardiac - diagnosis | Arrhythmias, Cardiac - genetics | Defibrillators | Cardiac arrhythmia | Epidemiology | Index Medicus
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8. Full Text Cardiac Sodium Channel Overlap Syndromes: Different Faces of SCN5A Mutations
by Remme, Carol Ann and Wilde, Arthur A.M and Bezzina, Connie R
Trends in cardiovascular medicine, ISSN 1050-1738, 2008, Volume 18, Issue 3, pp. 78 - 87
Cardiovascular | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Brugada Syndrome - genetics | Genetic Predisposition to Disease | Biophysical Phenomena | Brugada Syndrome - physiopathology | Humans | Sodium Channels - physiology | Biophysics | Mutation, Missense - genetics | Long QT Syndrome - physiopathology | Phenotype | Animals | DNA Mutational Analysis | Sick Sinus Syndrome - physiopathology | Long QT Syndrome - genetics | Sodium Channels - genetics | Sick Sinus Syndrome - genetics | Arrhythmia | Genetic aspects | Proteins | Cardiac arrhythmia | Mutation | Sodium | Cellular biology | Index Medicus
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