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Medicinal Research Reviews, ISSN 0198-6325, 07/2018, Volume 38, Issue 4, pp. 1404 - 1442
Tumor hypoxia is a common feature in most solid tumors and is associated with overexpression of the hypoxia response pathway. Overexpression of the... 
structure–activity relationship | tumor hypoxia | chemotype | angiogenesis | HIF‐1 inhibitors | HIF-1 inhibitors
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 4089 - 9
The second-in-class proteasome inhibitor (PI) carfilzomib (Kyprolis, Cfz) has contributed to a substantial advancement in multiple myeloma treatment by... 
OVEREXPRESSION | DEXAMETHASONE | SUBTYPES | MULTIDISCIPLINARY SCIENCES | LENALIDOMIDE | PHASE-2 | BORTEZOMIB | DIFFER | 20S PROTEASOMES | PROBES | Ubiquitin | Cell culture | Cell survival | γ-Interferon | Multiple myeloma | Proteasomes | siRNA | Patients | Proteasome inhibitors | Quality of life | Catalytic subunits
Journal Article
Critical Care Medicine, ISSN 0090-3493, 12/2015, Volume 43, Issue 12 Suppl 1, pp. 82 - 82
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 08/2016, Volume 16, Issue 19, pp. 2156 - 2168
Increased investments and development of new technologies in drug discovery have barely improved the outcome of medicinal entities in the drug discovery market... 
Anti-cancer | Drug discovery | Safety | Repurposing | Secondary indication | Approved drugs | CANCER-CELLS | KAPPA-B ACTIVATION | CHEMISTRY, MEDICINAL | INDUCED APOPTOSIS | 2 VEGFR2 GLYCOSYLATION | PROTEASE INHIBITORS | PHASE-II TRIAL | PROSTATE-CANCER | REPURPOSING DRUGS | TUMOR-GROWTH | SYSTEMS BIOLOGY
Journal Article
by Stanaway, Jeffrey D and Afshin, Ashkan and Gakidou, Emmanuela and Lim, Stephen S and Lim, Lee-Ling and Abate, Kalkidan Hassen and Abate, Degu and Abbafati, Cristiana and Abbasi, Nooshin and Abbastabar, Hedayat and Abd-Allah, Foad and Abdela, Jemal and Abdelalim, Ahmed and Abdollahpour, Ibrahim and Abdulkader, Rizwan Suliankatchi and Abebe, Zegeye and Abebe, Molla and Abera, Semaw F and Abil, Olifan Zewdie and Abraha, Haftom Niguse and Abrham, Aklilu Roba and Abu-Raddad, Laith Jamal and Abu-Rmeileh, Niveen ME and Accrombessi, Manfred Mario Kokou and Acharya, Dilaram and Acharya, Pawan and Adamu, Abdu A and Adane, Akilew Awoke and Adebayo, Oladimeji M and Adedoyin, Rufus Adesoji and Adekanmbi, Victor and Ademi, Zanfina and Adetokunboh, Olatunji O and Adib, Mina G and Admasie, Amha and Adsuar, Jose C and Afanvi, Kossivi Agbelenko and Afarideh, Mohsen and Agarwal, Gina and Aggarwal, Anju and Aghayan, Sargis Aghasi and Agrawal, Sutapa and Agrawal, Anurag and Ahmadi, Alireza and Ahmadi, Mehdi and Ahmadieh, Hamid and Ahmed, Muktar Beshir and Aichour, Amani Nidhal and Aichour, Miloud Taki Eddine and Aichour, Ibtihel and Akbari, Mohammad Esmaeil and Akinyemiju, Tomi and Akseer, Nadia and Al-Aly, Ziyad and Al-Eyadhy, Ayman and Al-Mekhlafi, Hesham M and Alahdab, Fares and Alam, Samiah and Alam, Tahiya and Alam, Khurshid and Alashi, Alaa and Alavian, Seyed Moayed and Alene, Kefyalew Addis and Ali, Komal and Ali, Syed Mustafa and Alijanzadeh, Mehran and Alizadeh-Navaei, Reza and Aljunid, Syed Mohamed and Alkerwi, Ala'a and Alla, François and Alsharif, Ubai and Altirkawi, Khalid and Alvis-Guzman, Nelson and Amare, Azmeraw T and Ammar, Walid and Anber, Nahla Hamed and Anderson, Jason A and Andrei, Catalina Liliana and Androudi, Sofia and Animut, Megbaru Debalkie and Anjomshoa, Mina and Ansha, Mustafa Geleto and Antó, Josep M and Antonio, Carl Abelardo T and Anwari, Palwasha and Appiah, Lambert Tetteh and Appiah, Seth Christopher Yaw and Arabloo, Jalal and Aremu, Olatunde and Ärnlöv, Johan and Artaman, Al and Aryal, Krishna K and Asayesh, Hamid and Ataro, Zerihun and Ausloos, Marcel and Avokpaho, Euripide F G A and Awasthi, Ashish and Ayala Quintanilla, Beatriz Paulina and Ayer, Rakesh and Ayuk, Tambe B and ... and GBD 2017 Risk Factor Collaborators and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
The Lancet, ISSN 0140-6736, 11/2018, Volume 392, Issue 10159, pp. 1923 - 1994
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor... 
MEDICINE, GENERAL & INTERNAL | CARDIOVASCULAR-DISEASES | CHOLESTEROL | TRENDS | BLOOD-PRESSURE | Health Risk Behaviors | Age Distribution | Global Burden of Disease - statistics & numerical data | Humans | Middle Aged | Child, Preschool | Infant | Male | Socioeconomic Factors | Young Adult | Life Expectancy | Global Health - trends | Global Health - statistics & numerical data | Aged, 80 and over | Adult | Disabled Persons - statistics & numerical data | Female | Environmental Exposure - statistics & numerical data | Child | Infant, Newborn | Occupational Exposure - statistics & numerical data | Quality-Adjusted Life Years | Risk Assessment | Occupational Exposure - adverse effects | Metabolic Diseases - epidemiology | Environmental Exposure - adverse effects | Global Burden of Disease - trends | Adolescent | Sex Distribution | Aged | Occupational Diseases - epidemiology | Drinking water | Sex | Environmental changes | Gestation | Occupational exposure | Epidemiology | Risk factors | Ecological risk assessment | Heterogeneity | Demographics | Risk assessment | Aging | Blood pressure | Mathematical models | Trends | Statistical modelling | Public health | Injuries | Age | Environmental assessment | Population growth | Statistical analysis | Drinking behavior | Decision making | Regional analysis | Causation | Health risks | Exposure | Metabolism | Risk analysis | Estimates | Studies | Charities | Population (statistical) | Statistical models | Body mass | Alcoholic beverages | Air pollution | Fatalities | Birth weight | Water pollution | Kidney diseases | Diabetes | Indoor air pollution | Health planning | Smoking | Sociodemographics | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 33, pp. 34446 - 34457
Among a number of non-coding RNAs, role of microRNAs (miRNAs) in cancer cell proliferation, cancer initiation, development and metastasis have been extensively... 
MiR-212 | MicroRNA | Autophagy | Prostate cancer | SIRT1 | miR-212 | prostate cancer | autophagy | MIR-132 | STATISTICS | GROWTH | microRNA | PROLIFERATION | DEATH | EXPRESSION | CELL BIOLOGY
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 08/2016, Volume 16, Issue 19, pp. 2156 - 2168
Increased investments and development of new technologies in drug discovery have barely improved the outcome of medicinal entities in the drug discovery market... 
Journal Article