Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (56) 56
Newspaper Article (8) 8
Patent (5) 5
Publication (4) 4
Book / eBook (2) 2
Book Review (1) 1
Dissertation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (17) 17
index medicus (17) 17
male (8) 8
chemistry, medicinal (7) 7
female (6) 6
research (6) 6
risk factors (6) 6
structure-activity relationship (6) 6
age (5) 5
chemistry (5) 5
drug discovery (5) 5
heterocyclic compounds (5) 5
human necessities (5) 5
hygiene (5) 5
medical and health sciences (5) 5
medical or veterinary science (5) 5
medicin och hälsovetenskap (5) 5
medicine, general & internal (5) 5
metallurgy (5) 5
organic chemistry (5) 5
preparations for medical, dental, or toilet purposes (5) 5
studies (5) 5
trends (5) 5
abridged index medicus (4) 4
adult (4) 4
analysis (4) 4
biochemistry & molecular biology (4) 4
cancer (4) 4
charities (4) 4
demographics (4) 4
drug design (4) 4
estimates (4) 4
folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (4) 4
growth (4) 4
health risks (4) 4
health sciences (4) 4
hypoxia (4) 4
hälsovetenskaper (4) 4
life expectancy (4) 4
mortality (4) 4
mycobacterium tuberculosis (4) 4
nepal (4) 4
oxazolidinone (4) 4
population (4) 4
public health, global health, social medicine and epidemiology (4) 4
risk analysis (4) 4
sex (4) 4
agents (3) 3
angiogenesis (3) 3
biological evaluation (3) 3
cell line, tumor (3) 3
death (3) 3
epidemiology (3) 3
general tagging of cross-sectional technologies spanning over several sections of the ipc (3) 3
general tagging of new technological developments (3) 3
global health - statistics & numerical data (3) 3
global health - trends (3) 3
health (3) 3
hiv (3) 3
hypoxia-inducible factor 1, alpha subunit - antagonists & inhibitors (3) 3
infant (3) 3
medicine (3) 3
microbial sensitivity tests (3) 3
mycobacterium-tuberculosis (3) 3
pharmacology & pharmacy (3) 3
prostate cancer (3) 3
public health (3) 3
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (3) 3
technologies for adaptation to climate change (3) 3
technologies or applications for mitigation or adaptation againstclimate change (3) 3
young adult (3) 3
-temospho (2) 2
acid analogs (2) 2
acquired immune deficiency syndrome--aids (2) 2
adolescent (2) 2
aged (2) 2
aging (2) 2
agronomy (2) 2
air pollution (2) 2
alcoholic beverages (2) 2
all-cause mortality (2) 2
animals (2) 2
anti-bacterial agents - chemical synthesis (2) 2
anti-bacterial agents - pharmacology (2) 2
antibacterial agent (2) 2
antitubercular agents - chemical synthesis (2) 2
antitubercular agents - pharmacology (2) 2
apoptosis - drug effects (2) 2
area under curve (2) 2
autophagy (2) 2
autophagy - physiology (2) 2
bacteria (2) 2
biomarkers, tumor - analysis (2) 2
biomarkers, tumor - genetics (2) 2
birth (2) 2
blotting, western (2) 2
cell biology (2) 2
cells (2) 2
cellular senescence - genetics (2) 2
census (2) 2
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Hypoxia‐inducible factor‐1 (HIF‐1) inhibitors from the last decade (2007 to 2016): A “structure–activity relationship” perspective
by Bhattarai, Deepak and Xu, Xuezhen and Lee, Kyeong
Medicinal Research Reviews, ISSN 0198-6325, 07/2018, Volume 38, Issue 4, pp. 1404 - 1442
Tumor hypoxia is a common feature in most solid tumors and is associated with overexpression of the hypoxia response pathway. Overexpression of the... 
structure–activity relationship | tumor hypoxia | chemotype | angiogenesis | HIF‐1 inhibitors | HIF-1 inhibitors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Hypoxia-inducible factor-1 (HIF-1) inhibitors from the last decade (2007 to 2016): A "structure-activity relationship" perspective
by Bhattarai, D and Xu, X and Lee, K
MEDICINAL RESEARCH REVIEWS, ISSN 0198-6325, 07/2018, Volume 38, Issue 4, pp. 1404 - 1442
Tumor hypoxia is a common feature in most solid tumors and is associated with overexpression of the hypoxia response pathway. Overexpression of the... 
ACID ANALOGS | CHEMISTRY, MEDICINAL | HIF-1 inhibitors | chemotype | SMALL-MOLECULE | angiogenesis | (HIF)-1 TRANSCRIPTIONAL ACTIVITY | TRUNCATED DEGUELIN DERIVATIVES | ANTICANCER AGENT | tumor hypoxia | CANCER-THERAPY | FACTOR-1-ALPHA INHIBITORS | 90 HSP90 INHIBITORS | BIOLOGICAL EVALUATION | PHARMACOLOGY & PHARMACY | structure-activity relationship | HIF-1-ALPHA INHIBITORS | HCT116 Cells | Humans | Neovascularization, Pathologic | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Structure-Activity Relationship | Drug Discovery | Neoplasms - drug therapy | Neoplasm Metastasis | Medical Oncology - trends | Inhibitory Concentration 50 | Hypoxia | Neoplasms - pathology | Drugstores | Chemotherapy | Drug discovery | College teachers | Pharmacy | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text H727 cells are inherently resistant to the proteasome inhibitor carfilzomib, yet require proteasome activity for cell survival and growth
by Lee, MJ and Miller, Z and Park, JE and Bhattarai, D and Lee, W and Kim, KB
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 4089 - 9
The second-in-class proteasome inhibitor (PI) carfilzomib (Kyprolis, Cfz) has contributed to a substantial advancement in multiple myeloma treatment by... 
OVEREXPRESSION | DEXAMETHASONE | SUBTYPES | MULTIDISCIPLINARY SCIENCES | LENALIDOMIDE | PHASE-2 | BORTEZOMIB | DIFFER | 20S PROTEASOMES | PROBES | Ubiquitin | Cell culture | Cell survival | γ-Interferon | Multiple myeloma | Proteasomes | siRNA | Patients | Proteasome inhibitors | Quality of life | Catalytic subunits
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text 322: EPIDEMIOLOGICAL PROFILE OF SNAKE BITES IN A PEDIATRIC INTENSIVE CARE UNIT OF EASTERN NEPAL
by Shah, Satish and Bhattarai, Suraj and Chaudhary, Manoj and Moktan, Deepak and Sah, Jeetendra
Critical Care Medicine, ISSN 0090-3493, 12/2015, Volume 43, Issue 12 Suppl 1, pp. 82 - 82
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. An Insight into Drug Repositioning for the Development of Novel Anti-Cancer Drugs
by Bhattarai, Deepak and Singh, Sarbijt and Jang, Yerin and Han, Seung Hyeon and Lee, Kyeong and Choi, Yongseok
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 08/2016, Volume 16, Issue 19, pp. 2156 - 2168
Increased investments and development of new technologies in drug discovery have barely improved the outcome of medicinal entities in the drug discovery market... 
Anti-cancer | Drug discovery | Safety | Repurposing | Secondary indication | Approved drugs | CANCER-CELLS | KAPPA-B ACTIVATION | CHEMISTRY, MEDICINAL | INDUCED APOPTOSIS | 2 VEGFR2 GLYCOSYLATION | PROTEASE INHIBITORS | PHASE-II TRIAL | PROSTATE-CANCER | REPURPOSING DRUGS | TUMOR-GROWTH | SYSTEMS BIOLOGY
Journal Article
Details down arrow
6. Full Text Nucleosides with Modified Sugar Ring: Synthesis and Biological Activities
by Sarbjit Singh and Deepak Bhattarai and Gajulapati Veeraswamy and Yongseok Choi and Kyeong Lee
Current Organic Chemistry, ISSN 1385-2728, 04/2016, Volume 20, Issue 8, pp. 856 - 897
In the recent few years, the emergence of nucleosides containing modified sugar ring or modified base moiety has gained much attention due to their enhanced... 
Selenonucleosides | Biologically active nucleosides | Functionalized nucleosides | Modified nucleosides | Thionucleosides | Fluorinated nucleosides | PYRIMIDINE PYRANONUCLEOSIDES | A ADENOSINE RECEPTOR | selenonucleosides | CHEMISTRY, ORGANIC | modified nucleosides | PHOSPHONIC ACID NUCLEOSIDES | POTENT ANTIVIRAL AGENTS | biologically active nucleosides | fluorinated nucleosides | L-CYCLOPENTENONE DERIVATIVES | thionucleosides | HERPES-SIMPLEX-VIRUS | ANTI-HIV ACTIVITY | 3,4-DIMETHOXYBENZYL PROTECTING GROUPS | CARBOCYCLIC 2'-OXA-3'-AZANUCLEOSIDES | S-ADENOSYLHOMOCYSTEINE HYDROLASE
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Sexual behaviour of people living with HIV attending a tertiary care government hospital in Kathmandu, Nepal: a cross sectional study
by Angdembe, Mirak Raj and Lohani, Shyam Prasad and Karki, Deepak Kumar and Bhattarai, Kreepa and Shrestha, Niraj
BMC Research Notes, ISSN 1756-0500, 11/2015, Volume 8, Issue 1, p. 629
Clinical improvements that follow antiretroviral therapy (ART) may lead to increase or resumption of high risk activities that could unintentionally result in... 
AIDS | Sexual behaviour | HIV | Antiretroviral therapy | Nepal | Anti-Retroviral Agents - therapeutic use | Cross-Sectional Studies | Humans | Sexual Behavior - statistics & numerical data | Logistic Models | Male | Hospitals, Public | Safe Sex - statistics & numerical data | Tertiary Healthcare | Social Class | Unsafe Sex - statistics & numerical data | Analysis of Variance | Risk-Taking | Adult | Female | HIV Infections - drug therapy | Surveys and Questionnaires | Condoms - utilization | Sexual Partners | Prevention | HIV patients | Research | HIV infection | Risk factors | Sexual behavior
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
by Stanaway, Jeffrey D and Afshin, Ashkan and Gakidou, Emmanuela and Lim, Stephen S and Lim, Lee-Ling and Abate, Kalkidan Hassen and Abate, Degu and Abbafati, Cristiana and Abbasi, Nooshin and Abbastabar, Hedayat and Abd-Allah, Foad and Abdela, Jemal and Abdelalim, Ahmed and Abdollahpour, Ibrahim and Abdulkader, Rizwan Suliankatchi and Abebe, Zegeye and Abebe, Molla and Abera, Semaw F and Abil, Olifan Zewdie and Abraha, Haftom Niguse and Abrham, Aklilu Roba and Abu-Raddad, Laith Jamal and Abu-Rmeileh, Niveen ME and Accrombessi, Manfred Mario Kokou and Acharya, Dilaram and Acharya, Pawan and Adamu, Abdu A and Adane, Akilew Awoke and Adebayo, Oladimeji M and Adedoyin, Rufus Adesoji and Adekanmbi, Victor and Ademi, Zanfina and Adetokunboh, Olatunji O and Adib, Mina G and Admasie, Amha and Adsuar, Jose C and Afanvi, Kossivi Agbelenko and Afarideh, Mohsen and Agarwal, Gina and Aggarwal, Anju and Aghayan, Sargis Aghasi and Agrawal, Sutapa and Agrawal, Anurag and Ahmadi, Alireza and Ahmadi, Mehdi and Ahmadieh, Hamid and Ahmed, Muktar Beshir and Aichour, Amani Nidhal and Aichour, Miloud Taki Eddine and Aichour, Ibtihel and Akbari, Mohammad Esmaeil and Akinyemiju, Tomi and Akseer, Nadia and Al-Aly, Ziyad and Al-Eyadhy, Ayman and Al-Mekhlafi, Hesham M and Alahdab, Fares and Alam, Samiah and Alam, Tahiya and Alam, Khurshid and Alashi, Alaa and Alavian, Seyed Moayed and Alene, Kefyalew Addis and Ali, Komal and Ali, Syed Mustafa and Alijanzadeh, Mehran and Alizadeh-Navaei, Reza and Aljunid, Syed Mohamed and Alkerwi, Ala'a and Alla, François and Alsharif, Ubai and Altirkawi, Khalid and Alvis-Guzman, Nelson and Amare, Azmeraw T and Ammar, Walid and Anber, Nahla Hamed and Anderson, Jason A and Andrei, Catalina Liliana and Androudi, Sofia and Animut, Megbaru Debalkie and Anjomshoa, Mina and Ansha, Mustafa Geleto and Antó, Josep M and Antonio, Carl Abelardo T and Anwari, Palwasha and Appiah, Lambert Tetteh and Appiah, Seth Christopher Yaw and Arabloo, Jalal and Aremu, Olatunde and Ärnlöv, Johan and Artaman, Al and Aryal, Krishna K and Asayesh, Hamid and Ataro, Zerihun and Ausloos, Marcel and Avokpaho, Euripide F G A and Awasthi, Ashish and Ayala Quintanilla, Beatriz Paulina and Ayer, Rakesh and Ayuk, Tambe B and ... and GBD 2017 Risk Factor Collaborators and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
The Lancet, ISSN 0140-6736, 11/2018, Volume 392, Issue 10159, pp. 1923 - 1994
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor... 
MEDICINE, GENERAL & INTERNAL | CARDIOVASCULAR-DISEASES | CHOLESTEROL | TRENDS | BLOOD-PRESSURE | Health Risk Behaviors | Age Distribution | Global Burden of Disease - statistics & numerical data | Humans | Middle Aged | Child, Preschool | Infant | Male | Socioeconomic Factors | Young Adult | Life Expectancy | Global Health - trends | Global Health - statistics & numerical data | Aged, 80 and over | Adult | Disabled Persons - statistics & numerical data | Female | Environmental Exposure - statistics & numerical data | Child | Infant, Newborn | Occupational Exposure - statistics & numerical data | Quality-Adjusted Life Years | Risk Assessment | Occupational Exposure - adverse effects | Metabolic Diseases - epidemiology | Environmental Exposure - adverse effects | Global Burden of Disease - trends | Adolescent | Sex Distribution | Aged | Occupational Diseases - epidemiology | Drinking water | Sex | Environmental changes | Gestation | Occupational exposure | Epidemiology | Risk factors | Ecological risk assessment | Heterogeneity | Demographics | Risk assessment | Aging | Blood pressure | Mathematical models | Trends | Statistical modelling | Public health | Injuries | Age | Environmental assessment | Population growth | Statistical analysis | Drinking behavior | Decision making | Regional analysis | Causation | Health risks | Exposure | Metabolism | Risk analysis | Estimates | Studies | Charities | Population (statistical) | Statistical models | Body mass | Alcoholic beverages | Air pollution | Fatalities | Birth weight | Water pollution | Kidney diseases | Diabetes | Indoor air pollution | Health planning | Smoking | Sociodemographics | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text MicroRNA-212 negatively regulates starvation induced autophagy in prostate cancer cells by inhibiting SIRT1 and is a modulator of angiogenesis and cellular senescence
by Ramalinga, Malathi and Roy, Arpita and Srivastava, Anvesha and Bhattarai, Asmita and Harish, Varsha and Suy, Simeng and Collins, Sean and Kumar, Deepak
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 33, pp. 34446 - 34457
Among a number of non-coding RNAs, role of microRNAs (miRNAs) in cancer cell proliferation, cancer initiation, development and metastasis have been extensively... 
MiR-212 | MicroRNA | Autophagy | Prostate cancer | SIRT1 | miR-212 | prostate cancer | autophagy | MIR-132 | STATISTICS | GROWTH | microRNA | PROLIFERATION | DEATH | EXPRESSION | CELL BIOLOGY
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. An Insight into Drug Repositioning for the Development of Novel Anti-Cancer Drugs
by Bhattarai, Deepak and Singh, Sarbijt and Jang, Yerin and Hyeon Han, Seung and Lee, Kyeong and Choi, Yongseok
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 08/2016, Volume 16, Issue 19, pp. 2156 - 2168
Increased investments and development of new technologies in drug discovery have barely improved the outcome of medicinal entities in the drug discovery market... 
Journal Article
Details down arrow