X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (34) 34
index medicus (32) 32
mice (27) 27
cancer (25) 25
humans (23) 23
cell biology (20) 20
research (18) 18
expression (16) 16
article (15) 15
genetic aspects (15) 15
genetics & heredity (13) 13
lung cancer (13) 13
tumors (12) 12
biochemistry & molecular biology (11) 11
cell line, tumor (11) 11
lung neoplasms - pathology (11) 11
gene expression (10) 10
developmental biology (9) 9
disease models, animal (9) 9
genomics (9) 9
lung neoplasms - genetics (9) 9
research paper (9) 9
adenocarcinoma (8) 8
adenocarcinoma of lung (8) 8
analysis (8) 8
genomes (8) 8
multidisciplinary sciences (8) 8
mutation (8) 8
signal transduction (8) 8
activation (7) 7
evolution (7) 7
metastasis (7) 7
mutations (7) 7
proteins (7) 7
tumorigenesis (7) 7
adenocarcinoma - genetics (6) 6
adenocarcinoma - pathology (6) 6
dead-box rna helicases - genetics (6) 6
gene mutations (6) 6
inhibition (6) 6
mice, inbred c57bl (6) 6
micrornas - genetics (6) 6
micrornas - metabolism (6) 6
oncology (6) 6
crispr (5) 5
drosophila (5) 5
drosophila - genetics (5) 5
female (5) 5
gene expression profiling (5) 5
gene expression regulation, neoplastic (5) 5
gene expression regulation, neoplastic - drug effects (5) 5
genes (5) 5
kinases (5) 5
lung neoplasms - metabolism (5) 5
metastases (5) 5
mice, transgenic (5) 5
microrna (5) 5
oncology, experimental (5) 5
phosphorylation (5) 5
respiratory tract diseases (5) 5
ribonuclease iii - genetics (5) 5
rodents (5) 5
antineoplastic agents - pharmacology (4) 4
biological sciences (4) 4
cell proliferation (4) 4
cell survival (4) 4
dicer (4) 4
digestive system diseases (4) 4
embryonic stem-cells (4) 4
endocrine system diseases (4) 4
gene expression regulation (4) 4
gene knockout techniques (4) 4
genetic engineering (4) 4
genome (4) 4
growth (4) 4
health aspects (4) 4
male (4) 4
metabolism (4) 4
mice, knockout (4) 4
mutation - genetics (4) 4
neoplasms (4) 4
phylogeny (4) 4
progression (4) 4
stem cells (4) 4
synteny (4) 4
transcription factors (4) 4
algorithms (3) 3
antineoplastic agents - therapeutic use (3) 3
apoptosis (3) 3
beta-catenin (3) 3
biotechnology & applied microbiology (3) 3
carrier proteins - metabolism (3) 3
cell line (3) 3
cell transformation, neoplastic - genetics (3) 3
cells, cultured (3) 3
chromosome inversion (3) 3
chromosomes (3) 3
clustered regularly interspaced short palindromic repeats (3) 3
dead-box rna helicases - metabolism (3) 3
development and progression (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Ancient Science of Life, ISSN 0257-7941, 01/2016, Volume 36, Issue 1, p. 42
Journal Article
Nature, ISSN 0028-0836, 12/2014, Volume 516, Issue 7531, pp. 428 - 431
Cancer is a multistep process that involves mutations and other alterations in oncogenes and tumour suppressor genes(1). Genome sequencing studies have... 
REPAIR | ENDONUCLEASE | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | LUNG ADENOCARCINOMA | CATENIN | CAS9 | SEQUENCING DATA | HALLMARKS | PROGRESSION | NUCLEASES | Genetic aspects | Gene mutations | Growth | Health aspects | Cancer cells | Tumors | Studies | Histopathology | Rodents | Genes | Genomics | Infections | Genomes | Tumorigenesis | Mutation | Kinases
Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7654, pp. 355 - 359
The heterogeneity of cellular states in cancer has been linked to drug resistance, cancer progression and the presence of cancer cells with properties of... 
INACTIVATION | TRANSCRIPTIONAL ACTIVATION | MULTIDISCIPLINARY SCIENCES | CRISPR-CAS9 | GENERATION | BETA-CATENIN | IDENTIFICATION | CANCER | CELL | TUMORIGENESIS | TUMOR INITIATION | Neoplasm Transplantation | Small Molecule Libraries - pharmacology | Adenocarcinoma - pathology | Stem Cell Niche | Adenocarcinoma of Lung | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Survival Rate | Wnt Proteins - metabolism | Wnt Proteins - chemistry | Disease Progression | Adenocarcinoma - metabolism | Animals | Neoplastic Stem Cells - metabolism | Protein Processing, Post-Translational - drug effects | Neoplastic Stem Cells - pathology | Female | Cell Proliferation - drug effects | Mice | Wnt Proteins - biosynthesis | Wnt Signaling Pathway | Adenocarcinoma | Lung cancer | Oncology, Experimental | Cancer cells | Stem cells | Research | Metastasis | Cancer | Cell proliferation | Drugs | Cell culture | Biotechnology | Transcription factors | Propagation | Transplantation | Adenoma | Drug resistance | Tissues | Anticancer properties | Metastases | Proteins | Heterogeneity | Signal transduction | Computed tomography | Technology | Intestine | Inhibition | Growth factors | Catenin | Translocation | Medical research | Subpopulations | Cell survival | Nutrition | Cloning | Cultures | Histology | Gene expression | Acyltransferase | Ribonucleic acid--RNA | Animal pathology | Inhibitors | Lymphocytes B | Microscopy | Reagents | Ligands | Genetic engineering | Tumors
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2017, Volume 23, Issue 11, pp. 1362 - 1368
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2016, Volume 113, Issue 42, pp. E6409 - E6417
Journal Article
Nature Biotechnology, ISSN 1087-0156, 06/2017, Volume 35, Issue 6, pp. 569 - 576
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 04/2014, Volume 111, Issue 16, pp. E1600 - E1609
Anaplastic thyroid carcinoma (ATC) has among the worst prognoses of any solid malignancy. The low incidence of the disease has in part precluded systematic... 
Vemurafenib | Anaplastic thyroid cancer | Genetically-engineered mouse model | Mek inhibitor | PHOSPHATIDYLINOSITOL 3-KINASE/AKT | MULTIDISCIPLINARY SCIENCES | vemurafenib | MEK inhibitor | TUMORS | BRAF(V600E) | genetically-engineered mouse model | INHIBITION | GENE | PATHWAY | anaplastic thyroid cancer | MUTATIONS | EXPRESSION | ASSOCIATION | TRANSGENIC MICE | Humans | Thyroid Carcinoma, Anaplastic | Thyroid Neoplasms - blood | Cell Differentiation - genetics | MAP Kinase Signaling System - genetics | Neoplasm Grading | Gene Expression Regulation, Neoplastic - drug effects | Carcinoma - pathology | Thyroid Gland - drug effects | Disease Models, Animal | Thyrotropin - blood | Carcinoma - drug therapy | Carcinoma - blood | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Tumor Suppressor Protein p53 - metabolism | Mice, Transgenic | Mutation - genetics | Disease Progression | Thyroid Cancer, Papillary | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Homozygote | Thyroid Neoplasms - genetics | Animals | MAP Kinase Signaling System - drug effects | Thyroid Neoplasms - drug therapy | Carcinoma, Papillary | Cell Differentiation - drug effects | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Thyroid Gland - pathology | Carcinoma - genetics | Cell Proliferation - drug effects | Mice | Thyroid Neoplasms - pathology | Survival analysis | Signal transduction | Thyroid cancer | Rodents | Oncology | Mutation | Kinases | Biological Sciences | PNAS Plus
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1 - 19
Activating mutations in the proto-oncogene KRAS are a hallmark of pancreatic ductal adenocarcinoma (PDAC), an aggressive malignancy with few effective... 
ACTIVATION | INHIBITION | K-RAS | PI3K | DUCTAL ADENOCARCINOMA | SUBTYPES | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | TUMOR | RESISTANCE | MUTATIONS | Adenocarcinoma | Drugs | CRISPR | Cell survival | MAP kinase | Genomes | Malignancy | Kinases | Gene expression | K-Ras protein | 1-Phosphatidylinositol 3-kinase | Metastases | Signal transduction | Signaling | Inhibitors | Protein kinase | Pancreatic cancer | Inhibition | Drug dependence | Mutation | Cancer
Journal Article
Journal Article