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by Waddell, Nicola and Pajic, Marina and Patch, Ann-Marie and Chang, David K and Kassahn, Karin S and Bailey, Peter and Johns, Amber L and Miller, David and Nones, Katia and Quek, Kelly and Quinn, Michael C. J and Robertson, Alan J and Fadlullah, Muhammad Z. H and Bruxner, Tim J. C and Christ, Angelika N and Harliwong, Ivon and Idrisoglu, Senel and Manning, Suzanne and Nourse, Craig and Nourbakhsh, Ehsan and Wani, Shivangi and Wilson, Peter J and Markham, Emma and Cloonan, Nicole and Anderson, Matthew J and Fink, J. Lynn and Holmes, Oliver and Kazakoff, Stephen H and Leonard, Conrad and Newell, Felicity and Poudel, Barsha and Song, Sarah and Taylor, Darrin and Waddell, Nick and Wood, Scott and Xu, Qinying and Wu, Jianmin and Pinese, Mark and Cowley, Mark J and Lee, Hong C and Jones, Marc D and Nagrial, Adnan M and Humphris, Jeremy and Chantrill, Lorraine A and Chin, Venessa and Steinmann, Angela M and Mawson, Amanda and Humphrey, Emily S and Colvin, Emily K and Chou, Angela and Scarlett, Christopher J and Pinho, Andreia V and Giry-Laterriere, Marc and Rooman, Ilse and Samra, Jaswinder S and Kench, James G and Pettitt, Jessica A and Merrett, Neil D and Toon, Christopher and Epari, Krishna and Nguyen, Nam Q and Barbour, Andrew and Zeps, Nikolajs and Jamieson, Nigel B and Graham, Janet S and Niclou, Simone P and Bjerkvig, Rolf and Grützmann, Robert and Aust, Daniela and Hruban, Ralph H and Maitra, Anirban and Iacobuzio-Donahue, Christine A and Wolfgang, Christopher L and Morgan, Richard A and Lawlor, Rita T and Corbo, Vincenzo and Bassi, Claudio and Falconi, Massimo and Zamboni, Giuseppe and Tortora, Giampaolo and Tempero, Margaret A and Gill, Anthony J and Eshleman, James R and Pilarsky, Christian and Scarpa, Aldo and Musgrove, Elizabeth A and Pearson, John V and Biankin, Andrew V and Grimmond, Sean M and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 02/2015, Volume 518, Issue 7540, pp. 495 - 501
Journal Article
Cancer research, ISSN 0008-5472, 08/2019, Volume 79, Issue 20, pp. 5316 - 5327
Pancreatic ductal adenocarcinoma (PDAC) is associated with significant fibrosis. Recent findings have highlighted the pro-fibrotic activity of tissue-resident... 
Journal Article
by Alexanov, Ludmil B and Nik-Zainal, Serena and Wedge, David C and Aparicio, Samuel A. J. R and Behjati, Sam and Biankin, Anew V and Bignell, Graham R and Bolli, Niccolò and Borg, Ake and Børresen-Dale, Anne-Lise and Boyault, Sanine and Burkhardt, Birgit and Butler, Adam P and Caldas, Carlos and Davies, Helen R and Desmedt, Christine and Eils, Roland and Eyfjörd, Jórunn Erla and Foekens, John A and Greaves, Mel and Hosoda, Fumie and Hutter, Barbara and Ilicic, Tomislav and Imbeaud, Sanine and Imielinsk, Marcin and Jäger, Natalie and Jones, David T. W and Jones, David and Knappskog, Stian and Kool, Marcel and Lakhani, Sunil R and López-Otín, Carlos and Martin, Sancha and Munshi, Nikhil C and Nakamura, Hiromi and Northcott, Paul A and Pajic, Marina and Papaemmanuil, Elli and Paradiso, Angelo and Pearson, John V and Puente, Xose S and Raine, Keiran and Ramakrishna, Manasa and Richardson, Anea L and Richter, Julia and Rosenstiel, Philip and Schlesner, Matthias and Schumacher, Ton N and Span, Paul N and Teague, Jon W and Totoki, Yasushi and Tutt, Anew N. J and Valdés-Mas, Rafael and van Buuren, Marit M and van 't Veer, Laura and Vincent-Salomon, Anne and Waddell, Nicola and Yates, Lucy R and Zucman-Rossi, Jessica and Futreal, P. Anew and McDermott, Ultan and Lichter, Peter and Meyerson, Matthew and Grimmond, Sean M and Siebert, Reiner and Campo, Elías and Shibata, Tatsuhiro and Pfister, Stefan M and Campbell, Peter J and Stratton, Michael R and Claviez, Alexander and Rosenwald, Aneas and Borkhardt, Arndt and Brors, Benedikt and Radlwimmer, Bernhard and Lawerenz, Chris and Lopez, Cristina and Langenberger, David and Karsch, Dennis and Lenze, Dido and Kube, Dieter and Leich, Ellen and Richter, Gesine and Korbel, Jan and Hoell, Jessica and Eils, Jürgen and Hezaveh, Kebriah and Trümper, Lorenz and Rosolowski, Maciej and Weniger, Marc and Rohde, Marius and Kreuz, Markus and Loeffler, Markus and Schilhabel, Markus and yling, Martin and Hansmann, Martin-Leo and Hummel, Michael and Szczepanowski, Monika and Ammerpohl, Ole and Stadler, Peter F and ... and ICGC Breast Canc Consortium and ICGC MMML-Seq Consortium and Australian Pancreatic Canc Genome and ICGC PedBrain and ICGC Breast Cancer Consortium and Australian Pancreatic Cancer Genome Initiative and Onkologi och Patologi, MV and Lund University and Oncology and Pathology, MV and Lunds universitet
Nature, ISSN 0028-0836, 2013, Volume 500, Issue 7463, pp. 415 - 421
Journal Article
by Bailey, Peter and Chang, David K and Nones, Katia and Johns, Amber L and Patch, Ann-Marie and Gingras, Marie-Claude and Miller, David K and Christ, Angelika N and Bruxner, Tim J. C and Quinn, Michael C and Nourse, Craig and Murtaugh, L. Charles and Harliwong, Ivon and Idrisoglu, Senel and Manning, Suzanne and Nourbakhsh, Ehsan and Wani, Shivangi and Fink, Lynn and Holmes, Oliver and Chin, Venessa and Anderson, Matthew J and Kazakoff, Stephen and Leonard, Conrad and Newell, Felicity and Waddell, Nick and Wood, Scott and Xu, Qinying and Wilson, Peter J and Cloonan, Nicole and Kassahn, Karin S and Taylor, Darrin and Quek, Kelly and Robertson, Alan and Pantano, Lorena and Mincarelli, Laura and Sanchez, Luis N and Evers, Lisa and Wu, Jianmin and Pinese, Mark and Cowley, Mark J and Jones, Marc D and Colvin, Emily K and Nagrial, Adnan M and Humphrey, Emily S and Chantrill, Lorraine A and Mawson, Amanda and Humphris, Jeremy and Chou, Angela and Pajic, Marina and Scarlett, Christopher J and Pinho, Andreia V and Giry-Laterriere, Marc and Rooman, Ilse and Samra, Jaswinder S and Kench, James G and Lovell, Jessica A and Merrett, Neil D and Toon, Christopher W and Epari, Krishna and Nguyen, Nam Q and Barbour, Andrew and Zeps, Nikolajs and Moran-Jones, Kim and Jamieson, Nigel B and Graham, Janet S and Duthie, Fraser and Oien, Karin and Hair, Jane and Grützmann, Robert and Maitra, Anirban and Iacobuzio-Donahue, Christine A and Wolfgang, Christopher L and Morgan, Richard A and Lawlor, Rita T and Corbo, Vincenzo and Bassi, Claudio and Rusev, Borislav and Capelli, Paola and Salvia, Roberto and Tortora, Giampaolo and Mukhopadhyay, Debabrata and Petersen, Gloria M and Munzy, Donna M and Fisher, William E and Karim, Saadia A and Eshleman, James R and Hruban, Ralph H and Pilarsky, Christian and Morton, Jennifer P and Sansom, Owen J and Scarpa, Aldo and Musgrove, Elizabeth A and Bailey, Ulla-Maja Hagbo and Hofmann, Oliver and Sutherland, Robert L and Wheeler, David A and Gill, Anthony J and Gibbs, Richard A and Pearson, John V and Waddell, Nicola and ... and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 03/2016, Volume 531, Issue 7592, pp. 47 - 52
Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently mutated genes that aggregate into 10 pathways: KRAS, TGF-beta,... 
PATHWAYS | METASTASIS | DUCTAL ADENOCARCINOMA | PACKAGE | MULTIDISCIPLINARY SCIENCES | TUMOR | MUTATIONS | DIFFERENTIATION | Pancreatic Neoplasms - metabolism | Prognosis | Hepatocyte Nuclear Factor 3-beta - genetics | Genomics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Gene Expression Regulation, Neoplastic | Transcriptome | Hepatocyte Nuclear Factor 3-gamma - genetics | Gene Regulatory Networks | Histone Demethylases - genetics | Tumor Suppressor Protein p53 - genetics | Carcinoma, Pancreatic Ductal - genetics | DNA Methylation | Tumor Suppressor Proteins - genetics | Carcinoma, Pancreatic Ductal - classification | Trans-Activators - genetics | Pancreatic Neoplasms - classification | Transcription, Genetic | Nuclear Proteins - genetics | Carcinoma, Pancreatic Ductal - immunology | Genes, Neoplasm - genetics | Basic Helix-Loop-Helix Transcription Factors - genetics | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Carcinoma, Pancreatic Ductal - pathology | Genome, Human - genetics | Homeodomain Proteins - genetics | Animals | Pancreatic Neoplasms - immunology | Survival Analysis | Cell Line, Tumor | Mice | Physiological aspects | Pancreatic cancer | Methods | Genes | Genomes | Mutation | Gene expression | Tumors
Journal Article
by Pérez-Mancera, Pedro A and Rust, Alistair G and Van Der Weyden, Louise and Kristiansen, Glen and Li, Allen and Sarver, Aaron L and Silverstein, Kevin A. T and Grützmann, Robert and Aust, Daniela and Rümmele, Petra and Knösel, Thomas and Herd, Colin and Stemple, Derek L and Kettleborough, Ross and Brosnan, Jacqueline A and Li, Ang and Morgan, Richard and Knight, Spencer and Yu, Jun and Stegeman, Shane and Collier, Lara S and Ten Hoeve, Jelle J and De Ridder, Jeroen and Klein, Alison P and Goggins, Michael and Hruban, Ralph H and Chang, David K and Biankin, Andrew V. Wessels and Grimmond, Sean M and Wessels, Lodewyk F. A and Wood, Stephen A and Iacobuzio-Donahue, Christine A and Pilarsky, Christian and Largaespada, David A and Adams, David J and Tuveson, David A and Bienkin, Andrew V and Johns, Amber L and Mawson, Amanda and Cheng, David K and Brancato, Mary-Anne L and Rowe, Sarah J and Simpson, Skye L and Martyn-Smith, Mona and Chantrill, Lorraine A and Chin, Venessa T and Chou, Angela and Cowley, Mark J and Humphris, Jeremy L and Jones, Marc D and Scott Mead, R and Nagrial, Adnan M and Pajic, Marina and Pettit, Jessica and Pinese, Mark and Rooman, Ilse and Wu, Jianmin and Daly, Roger J and Musgrove, Elizabeth A and Sutherland, Robert L and Grimond, Sean M and Waddell, Nicola and Kassahn, Karin S and Miller, David K and Wilson, Peter J and Patch, Ann-Marie and Song, Sarah and Harliwong, Ivon and Idrisoglu, Senel and Nourse, Craig and Nourbakhsh, Ehsan and Manning, Suzanne and Wani, Shivangi and Gongora, Milena and Anderson, Matthew and Holmes, Oliver and Leonard, Conrad and Taylor, Darrin and Wood, Scott and Xu, Christina and Nones, Katia and Lynn Fink, J and Christ, Angelika and Bruxner, Tim and Cloonan, Nicole and Newell, Felicity and Pearson, John V and Samra, Jaswinder S and Gill, Anthony J and Pavlakis, Nick and Guminski, Alex and Toon, Christopher and Blankin, Andrew V and Asghari, Ray and Merrett, Neil D and Pavey, Darren A and Das, Amithabad and Cosman, Peter H and Ismail, Kasim and O'Connor, Chelsie and ... and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 06/2012, Volume 486, Issue 7402, pp. 266 - 270
Journal Article