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Journal Article
Cell reports (Cambridge), ISSN 2211-1247, 2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
Cell (Cambridge), ISSN 0092-8674, 11/2013, Volume 155, Issue 5, p. 997
Autism spectrum disorder (ASD) is a complex developmental syndrome of unknown etiology. Recent studies employing exome- and genome-wide sequencing have... 
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2013, Volume 155, Issue 5, pp. 997 - 1007
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 1, p. e16465
...Author(s): Candace Bichsel 1 , Dennis K. Neeld 1 , Takashi Hamazaki 2 , Donghai Wu 3 , Lung-Ji Chang 1 , Lijun Yang 2 , Naohiro Terada 2 , Shouguang Jin 1... 
PSEUDOMONAS-AERUGINOSA | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | LENTIVIRAL VECTOR | CRE RECOMBINASE | INFECTION | INDUCTION | EXCISION | FIBROBLASTS | III SECRETION SYSTEM | Transcription Factors - administration & dosage | Bacteria - metabolism | Bacterial Secretion Systems | Humans | Bacterial Toxins - pharmacokinetics | Cells, Cultured | Transcription Factors - pharmacokinetics | Nuclear Localization Signals | Cellular Reprogramming | Integrases | Pluripotent Stem Cells - metabolism | Nuclear Proteins - administration & dosage | Pseudomonas aeruginosa - chemistry | Animals | Cell Nucleus - metabolism | ADP Ribose Transferases - administration & dosage | Recombination, Genetic | Cell Line, Tumor | ADP Ribose Transferases - pharmacokinetics | Bacterial Toxins - administration & dosage | Cell Differentiation | Mice | Drug Delivery Systems - methods | Nuclear Proteins - pharmacokinetics | DNA binding proteins | Virulence (Microbiology) | Sarcoma | Embryonic stem cells | Health aspects | Transcription factors | Recombination | Laboratories | Toxicity | Embryo cells | Stem cell transplantation | Cytotoxicity | Biology | Infections | Recombinase | Nuclei | Proteins | Allografts | E coli | Pseudomonas aeruginosa | Bacteria | Localization | Deoxyribonucleic acid--DNA | Bacterial infections | Gene expression | Cre recombinase | Medicine | Studies | Pathology | Antibiotics | Mutagenesis | Plasmids | Stem cells | Genetic engineering | Pluripotency | Cytoplasm | Deoxyribonucleic acid | DNA
Journal Article
Cell, ISSN 0092-8674, 11/2018, Volume 175, Issue 4, pp. 1088 - 1104.e23
Despite the known causality of copy number variations (CNVs) to human neurodevelopmental disorders, the mechanisms behind each genes’ contribution to the... 
mitochondria | Neurodevelopment | ATP synthesis | genomics | CNV | neocortex | autism spectrum disorder | neurodevelopmental disorders | intellectual disability | Williams syndrome
Journal Article
Journal Article
01/2012, Volume 75, Issue 12
The overexpression of exogenous genes has proven a powerful application in molecular biology and has recently been applied to direct cellular differentiation... 
Book Chapter
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2018, Volume 362, Issue 6420, pp. eaat7615 - 1264
Journal Article
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