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2007, Wyd. 1., ISBN 8371834373, 159
Book
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, p. e0177805
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2004, Volume 279, Issue 12, pp. 11320 - 11326
Recently, we demonstrated that ceramide kinase, and its product, ceramide 1-phosphate (Cer-1-P), were mediators of arachidonic acid released in cells in... 
Enzyme Activators - pharmacology | Cytosol - enzymology | RNA Interference | Base Sequence | Humans | Fluorescent Antibody Technique | Cell Line, Tumor | Phospholipases A - metabolism | Phospholipases A2 | Ceramides - pharmacology
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 08/2018, Volume 78, Issue 16 Supplement, pp. A073 - A073
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2013, Volume 123, Issue 10, pp. 4344 - 4358
Escape of prostate cancer (PCa) cells from ionizing radiation-induced (IR-induced) killing leads to disease progression and cancer relapse. The influence of... 
MEDICINE, RESEARCH & EXPERIMENTAL | SPHINGOLIPID BIOSYNTHESIS | INDUCED APOPTOSIS | RAT EMBRYO CELLS | DOWN-REGULATION | GENE-EXPRESSION | RANDOMIZED CONTROLLED-TRIAL | C-JUN | IONIZING-RADIATION | HUMAN GLIOMA-CELLS | ADENOCARCINOMA CELL-LINE | Prostatic Neoplasms - radiotherapy | Acid Ceramidase - antagonists & inhibitors | Humans | Radiation Tolerance | Male | Neoplasm Recurrence, Local - enzymology | Transcription Factor AP-1 - metabolism | Radiation-Sensitizing Agents - administration & dosage | Acid Ceramidase - metabolism | Amides - pharmacology | Promoter Regions, Genetic | Prostatic Neoplasms - pathology | Gene Expression | Acid Ceramidase - genetics | Neoplasm Recurrence, Local - prevention & control | Radiation-Sensitizing Agents - pharmacology | Transcriptional Activation - radiation effects | Injections, Intraperitoneal | Sphingolipids - metabolism | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Proto-Oncogene Proteins c-jun - metabolism | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Protein Binding | Gene Expression Regulation, Neoplastic - radiation effects | Mice | Propanolamines - administration & dosage | Propanolamines - pharmacology | Amides - administration & dosage | Enzyme Induction - radiation effects | Enzymes | Care and treatment | Ionizing radiation | Hydrolases | Genetic aspects | Research | Properties | Radiotherapy | Prostate cancer | Proteins | Studies | Cell culture | Radiation therapy | Kinases | Gene expression | Cancer therapies | Tumors
Journal Article
International Journal of Clinical Oncology, ISSN 1341-9625, 6/2015, Volume 20, Issue 3, pp. 438 - 446
Journal Article
Cancer Research, ISSN 0008-5472, 12/2017, Volume 77, Issue 24, pp. 6950 - 6952
Protein N-myristoylation enables localization to membranes and helps maintain protein conformation and function. N-myristoyltransferases (NMT) catalyze co-or... 
PROTEIN N-MYRISTOYLATION | ANDROGEN RECEPTOR | APOPTOSIS | TYROSINE PHOSPHORYLATION | B13 | ONCOLOGY | ANALOGS | FAMILY KINASES | MYRISTOYLTRANSFERASE | SPHINGOLIPIDS | N-MYRISTOYLTRANSFERASE-1 | Acyltransferases - antagonists & inhibitors | Phosphotransferases - metabolism | Prostatic Neoplasms - metabolism | Humans | Protein Processing, Post-Translational - genetics | Male | Structure-Activity Relationship | Mutation, Missense | Acyltransferases - metabolism | Acyltransferases - genetics | Proto-Oncogene Proteins pp60(c-src) - chemistry | Phosphorylation - genetics | Prostatic Neoplasms - genetics | Tumor Suppressor Proteins - genetics | HEK293 Cells | Phosphorylation - drug effects | Prostatic Neoplasms - drug therapy | Prostatic Neoplasms - pathology | Acyltransferases - physiology | Tumor Suppressor Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Mice, SCID | Enzyme Inhibitors - therapeutic use | Disease Progression | Protein Processing, Post-Translational - physiology | Myristic Acid - metabolism | Animals | Proto-Oncogene Proteins pp60(c-src) - genetics | Proto-Oncogene Proteins pp60(c-src) - metabolism | Mice | Amino Acid Substitution | Cell proliferation | Membranes | Kinases | Optimization | Myristoylation | Anticancer properties | Proteins | N-Myristoyltransferase | Enzymatic activity | Biocompatibility | Localization | Chemical synthesis | Invasiveness | Blocking | Pharmacology | Src protein | Signaling | Androgens | Inhibitors | Antitumor activity | Position (location) | Prostate cancer | Prostate | Protein structure | Cancer | Index Medicus | Src family kinases | NMT | prostate tumorigenesis
Journal Article
BMC Cancer, ISSN 1471-2407, 01/2014, Volume 14, Issue 1, p. 24
Background: Ceramide is a bioeffector that mediates various cellular processes, including apoptosis. However, the mechanism underlying ceramide function in... 
Ceramide | Apoptosis sensitization | cIAP1 | Fas | Bcl-xL | xIAP | ACTIVATION | CD95 | FAS-MEDIATED APOPTOSIS | ANTAGONISTS INDUCE | ACID CERAMIDASE | IN-VITRO | SYNTHASE 6 | ONCOLOGY | RESISTANCE | NF-KAPPA-B | EXPRESSION | Breast Neoplasms - secondary | Colonic Neoplasms - genetics | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Colonic Neoplasms - drug therapy | Humans | Drug Resistance, Neoplasm | Molecular Targeted Therapy | fas Receptor - metabolism | Colonic Neoplasms - metabolism | Breast Neoplasms - metabolism | Dose-Response Relationship, Drug | Transfection | RNA Interference | Female | Antineoplastic Agents - pharmacology | Inhibitor of Apoptosis Proteins - metabolism | Colonic Neoplasms - secondary | Breast Neoplasms - drug therapy | Ceramides - pharmacology | Disease Progression | X-Linked Inhibitor of Apoptosis Protein - genetics | Ubiquitin-Protein Ligases | Xenograft Model Antitumor Assays | Pyridinium Compounds - pharmacology | Animals | Breast Neoplasms - genetics | Signal Transduction - drug effects | X-Linked Inhibitor of Apoptosis Protein - metabolism | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Propanolamines - pharmacology | Care and treatment | Colon cancer | Patient outcomes | Cancer cells | Physiological aspects | Development and progression | Breast cancer | Research
Journal Article
Journal Article