Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
oncology (12) 12
science & technology (12) 12
animals (10) 10
radiotherapy (10) 10
humans (9) 9
life sciences & biomedicine (9) 9
mice (7) 7
tumors (7) 7
cancer (5) 5
cell line, tumor (5) 5
cells (4) 4
hematology, oncology and palliative medicine (4) 4
positron-emission tomography (4) 4
disease models, animal (3) 3
female (3) 3
hematology (3) 3
hypoxia (3) 3
immunotherapy (3) 3
lung-cancer (3) 3
male (3) 3
metabolism (3) 3
mitochondria (3) 3
multidisciplinary sciences (3) 3
nitroimidazoles - pharmacology (3) 3
oxidative stress (3) 3
radiation (3) 3
radiation therapy (3) 3
radiology nuclear medicine and imaging (3) 3
rats (3) 3
science & technology - other topics (3) 3
abscopal effect (2) 2
analysis (2) 2
antineoplastic agents - pharmacology (2) 2
antioxidant (2) 2
biochemistry (2) 2
biology and life sciences (2) 2
biotechnology (2) 2
caix (2) 2
cancer cells (2) 2
cancer therapies (2) 2
cancer treatment (2) 2
carbonic anhydrase inhibitors - pharmacology (2) 2
carbonic anhydrase ix (2) 2
cell biology (2) 2
cell proliferation - drug effects (2) 2
cell survival (2) 2
cell survival - radiation effects (2) 2
clinical medicine (2) 2
complex i (2) 2
dose-response relationship, radiation (2) 2
doxorubicin (2) 2
enzymes (2) 2
enzymology (2) 2
gene (2) 2
gene expression (2) 2
generation (2) 2
glutamine metabolism (2) 2
glutathione (2) 2
glycolysis (2) 2
health aspects (2) 2
heterogeneity (2) 2
hif-1 (2) 2
hif-1 alpha (2) 2
hypoxia-activated prodrug (2) 2
ionizing-radiation (2) 2
medicine (2) 2
medicine and health sciences (2) 2
memory effect (2) 2
metabolic inhibition (2) 2
metformin (2) 2
mice, nude (2) 2
mitochondrial dna (2) 2
mitochondrial-dna (2) 2
mtdna (2) 2
neoplasms - diagnosis (2) 2
neoplasms - metabolism (2) 2
neoplasms - radiotherapy (2) 2
nitroimidazoles - therapeutic use (2) 2
non-small cell lung cancer (2) 2
original research (2) 2
oxphos (2) 2
phosphoramide mustards - pharmacology (2) 2
phosphoramide mustards - therapeutic use (2) 2
physiological aspects (2) 2
proteins (2) 2
radiation dosage (2) 2
radiation-sensitizing agents - pharmacology (2) 2
radiology, nuclear medicine & medical imaging (2) 2
research article (2) 2
rhabdomyosarcoma - radiotherapy (2) 2
ros (2) 2
science (2) 2
sirt3 (2) 2
superoxide-dismutase (2) 2
survival curves (2) 2
th-302 (2) 2
therapy (2) 2
toxicology (2) 2
treatment outcome (2) 2
tumor cells, cultured (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text A novel concept for tumour targeting with radiation: Inverse dose-painting or targeting the “Low Drug Uptake Volume”
by Yaromina, Ala and Granzier, Marlies and Biemans, Rianne and Lieuwes, Natasja and van Elmpt, Wouter and Shakirin, Georgy and Dubois, Ludwig and Lambin, Philippe
Radiotherapy and oncology, ISSN 0167-8140, 2017, Volume 124, Issue 3, pp. 513 - 520
Hematology, Oncology and Palliative Medicine | Hypoxia-activated prodrug | HX4 PET | Rat rhabdomyosarcoma | Dose-painting | Growth delay | Radiotherapy | TH-302 | NECK-CANCER PATIENTS | NUDE-MICE | PROGNOSTIC VALUE | LUNG-CANCER | PHASE-I TRIAL | ACTIVATED PRODRUG TH-302 | SQUAMOUS-CELL CARCINOMA | INTERNATIONAL MULTICENTER | LOCAL-CONTROL | FRACTIONATED-IRRADIATION | Radiotherapy Dosage | Humans | Rats | Rhabdomyosarcoma - pathology | Male | Tumor Burden | Rhabdomyosarcoma - diagnostic imaging | Positron Emission Tomography Computed Tomography | Rhabdomyosarcoma - radiotherapy | Animals | Nitroimidazoles - therapeutic use | Phosphoramide Mustards - therapeutic use | Radiotherapy Planning, Computer-Assisted | Radiation | Tumors | Pets | Tracers (Biology) | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Mitochondrial Dysfunction Inhibits Hypoxia-Induced HIF-1 alpha Stabilization and Expression of Its Downstream Targets
by van Gisbergen, Marike W and Offermans, Kelly and Voets, An M and Lieuwes, Natasja G and Biemans, Rianne and Hoffmann, Roland F and Dubois, Ludwig J and Lambin, Philippe
Frontiers in oncology, ISSN 2234-943X, 05/2020, Volume 10, pp. 770 - 770
COMPLEX I | CELLS | OXIDATIVE STRESS | HIF-1 alpha | mtDNA | mitochondria | OXPHOS | CANCER | SIRT3 | HETEROGENEITY | HIF-1 | CAIX | GENE | ROS | Metformin | Life Sciences & Biomedicine | Oncology | Science & Technology | HIF-1α
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Use of a Luciferase-Expressing Orthotopic Rat Brain Tumor Model to Optimize a Targeted Irradiation Strategy for Efficacy Testing with Temozolomide
by Mowday, Alexana M and Lieuwes, Natasja G and Biemans, Rianne and Marcus, Damienne and Rezaeifar, Behzad and Reniers, Brigitte and Verhaegen, Frank and Theys, Jan and Dubois, Ludwig J
Cancers, ISSN 2072-6694, 06/2020, Volume 12, Issue 6, p. 1585
temozolomide | CT imaging | CELLS | targeted radiotherapy | INFILTRATING LYMPHOCYTES | orthotopic models | bioluminescence imaging | standard of care | HYPOXIA | glioblastoma | THERAPY | MICE | RADIOTHERAPY | PROGRESSION | Life Sciences & Biomedicine | Oncology | Science & Technology | Neuroimaging | Invasiveness | Brain tumors | Brain cancer | Glioblastoma | Radiation therapy | Survival | Glioblastoma multiforme | Animals | Computed tomography | Medical prognosis | Hypoxia | Clinical medicine | Planning | Temozolomide | Tumors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text In vivo optical imaging of MMP2 immuno protein antibody: tumor uptake is associated with MMP2 activity
by Panth, Kranthi Marella and van den Beucken, Twan and Biemans, Rianne and Lieuwes, Natasja G and Weber, Marcel and Losen, Mario and Yaromina, Ala and Dubois, Ludwig J and Lambin, Philippe
Scientific reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, pp. 22198 - 22198
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neoplasms - metabolism | Gene Expression | Reproducibility of Results | Matrix Metalloproteinase 2 - metabolism | Tumor Microenvironment | Molecular Imaging - methods | Neoplasms - diagnosis | Integrin alphaVbeta3 - metabolism | Mice, Knockout | Matrix Metalloproteinase 2 - genetics | Animals | Heterografts | Integrin alphaVbeta3 - genetics | Neoplasms - genetics | Antibodies - immunology | Cell Line, Tumor | Mice | Enzyme Activation | Matrix Metalloproteinase 2 - immunology | Optical Imaging - methods | Disease Models, Animal | Lysates | Angiogenesis | Animal models | Gelatin | Tumorigenesis | Metalloproteinase | Matrix metalloproteinase | Tumors | Gelatinase A | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Synthesis and in Vivo Biological Evaluation of 68Ga-Labeled Carbonic Anhydrase IX Targeting Small Molecules for Positron Emission Tomography
by Sneddon, Deborah and Niemans, Raymon and Bauwens, Matthias and Yaromina, Ala and van Kuijk, Simon J. A and Lieuwes, Natasja G and Biemans, Rianne and Pooters, Ivo and Pellegrini, Paul A and Lengkeek, Nigel A and Greguric, Ivan and Tonissen, Kathryn F and Supuran, Claudiu T and Lambin, Philippe and Dubois, Ludwig and Poulsen, Sally-Ann
Journal of medicinal chemistry, ISSN 0022-2623, 07/2016, Volume 59, Issue 13, pp. 6431 - 6443
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Evofosfamide sensitizes esophageal carcinomas to radiation without increasing normal tissue toxicity
by Spiegelberg, Linda and van Hoof, Stefan J and Biemans, Rianne and Lieuwes, Natasja G and Marcus, Damiënne and Niemans, Raymon and Theys, Jan and Yaromina, Ala and Lambin, Philippe and Verhaegen, Frank and Dubois, Ludwig J
Radiotherapy and oncology, ISSN 0167-8140, 12/2019, Volume 141, pp. 247 - 255
Therapeutic index | Radiotherapy | Long-term lung fibrosis | TH-302 | Esophageal cancer | Short-term gut toxicity | TOTAL-BODY IRRADIATION | TUMOR HYPOXIA | HYPOXIA-ACTIVATED PRODRUG | DOXORUBICIN | INJURY | COMBINATION | CANCER | PRO-DRUG TH-302 | PHASE-I | Oncology | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Nitroimidazoles - pharmacology | Phosphoramide Mustards - pharmacology | Humans | Radiation-Sensitizing Agents - pharmacology | Male | Esophageal Neoplasms - radiotherapy | Nitroimidazoles - adverse effects | Animals | Phosphoramide Mustards - adverse effects | Squamous Cell Carcinoma of Head and Neck - radiotherapy | Cell Line, Tumor | Female | Mice | Adenocarcinoma - radiotherapy | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text TH-302 in Combination with Radiotherapy Enhances the Therapeutic Outcome and Is Associated with Pretreatment [F-18]HX4 Hypoxia PET Imaging
by Peeters, Sarah G. J. A and Zegers, Catharina M. L and Biemans, Rianne and Lieuwes, Natasja G and van Stiphout, Ruud G. P. M and Yaromina, Ala and Sun, Jessica D and Hart, Charles P and Windhorst, Albert D and van Elmpt, Wouter and Dubois, Ludwig J and Lambin, Philippe
Clinical cancer research, ISSN 1078-0432, 07/2015, Volume 21, Issue 13, pp. 2984 - 2992
Life Sciences & Biomedicine | Oncology | Science & Technology | Nitroimidazoles - pharmacology | Phosphoramide Mustards - pharmacology | Rats | Treatment Outcome | Antineoplastic Agents - therapeutic use | Lung Neoplasms - therapy | Positron-Emission Tomography | Chemoradiotherapy | Cell Hypoxia | Xenograft Model Antitumor Assays | Carcinoma, Non-Small-Cell Lung - therapy | Animals | Imidazoles | Nitroimidazoles - therapeutic use | Phosphoramide Mustards - therapeutic use | Triazoles | Lung Neoplasms - diagnostic imaging | Antineoplastic Agents - pharmacology | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Radiopharmaceuticals | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Mitochondrial Dysfunction Inhibits Hypoxia-Induced HIF-1[ALPHA] Stabilization and Expression of Its Downstream Targets
by Offermans, Kelly and Van Gisbergen, Marike W and Voets, An M and Hoffmann, Roland F and Biemans, Rianne and Dubois, Ludwig J and Lieuwes, Natasja G
Frontiers in oncology, ISSN 2234-943X, 05/2020
Mitochondrial DNA
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Targeting glucose and glutamine metabolism combined with radiation therapy in non-small cell lung cancer
by Meijer, Tineke W. H and Peeters, Wenny J. M and Dubois, Ludwig J and van Gisbergen, Marike W and Biemans, Rianne and Venhuizen, Jan-Henik and Span, Paul N and Bussink, Johan
Lung cancer (Amsterdam, Netherlands), ISSN 0169-5002, 12/2018, Volume 126, pp. 32 - 40
MITOCHONDRIAL | ADENOCARCINOMA | Glutamine metabolism | SENSITIVITY | CLASSIFICATION | Radiotherapy | DEPENDENCIES | INHIBITION | Metabolic inhibition | GLUTATHIONE | Non-small cell lung cancer | Glycolysis | EXPRESSION | LONIDAMINE
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: A new concept of dual targeting drugs
by Dubois, Ludwig and Peeters, Sarah G.J.A and van Kuijk, Simon J.A and Yaromina, Ala and Lieuwes, Natasja G and Saraya, Ruchi and Biemans, Rianne and Rami, Marouan and Parvathaneni, Nanda Kumar and Vullo, Daniela and Vooijs, Marc and Supuran, Claudiu T and Winum, Jean-Yves and Lambin, Philippe
Radiotherapy and oncology, ISSN 0167-8140, 2013, Volume 108, Issue 3, pp. 523 - 528
Hematology, Oncology and Palliative Medicine | Sulfamide | Carbonic anhydrase IX (CAIX) | 5-Nitroimidazole | Radiotherapy | Dual targeting | Carbonic Anhydrases - physiology | Animals | Nitroimidazoles - pharmacology | Antigens, Neoplasm - physiology | Humans | Radiation-Sensitizing Agents - pharmacology | Colorectal Neoplasms - radiotherapy | Cell Line, Tumor | Mice | Carbonic Anhydrase Inhibitors - pharmacology | Carbonic Anhydrase IX | Health aspects | Tumors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Mitochondrial Dysfunction Inhibits Hypoxia-Induced HIF-1 alpha Stabilization and Expression of Its Downstream Targets
by van Gisbergen, Marike W and Offermans, Kelly and Voets, An M and Lieuwes, Natasja G and Biemans, Rianne and Hoffmann, Roland F and Dubois, Ludwig J and Lambin, Philippe
Frontiers in oncology, ISSN 2234-943X, 05/2020, Volume 10
COMPLEX I | CELLS | OXIDATIVE STRESS | HIF-1 alpha | mtDNA | mitochondria | OXPHOS | CANCER | SIRT3 | HETEROGENEITY | HIF-1 | CAIX | GENE | ROS | Metformin
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Targeting glucose and glutamine metabolism combined with radiation therapy in non-small cell lung cancer
by Meijer, Tineke W.H and Peeters, Wenny J.M and Dubois, Ludwig J and van Gisbergen, Marike W and Biemans, Rianne and Venhuizen, Jan-Hendrik and Span, Paul N and Bussink, Johan
Lung cancer (Amsterdam, Netherlands), ISSN 0169-5002, 12/2018, Volume 126, pp. 32 - 40
Glycolysis | Radiotherapy | Metabolic inhibition | Glutamine metabolism | Non-small cell lung cancer | Respiratory System | Oncology | Life Sciences & Biomedicine | Science & Technology | Glucose metabolism | Squamous cell carcinoma | Radiation | Physiological aspects | Lung cancer, Small cell | Glucose | Lung cancer, Non-small cell | Cells | Dextrose | Glutamine
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Combination of radiotherapy with the immunocytokine L19-IL2: Additive effect in a NK cell dependent tumour model
by Rekers, Nicolle H and Zegers, Catharina M.L and Yaromina, Ala and Lieuwes, Natasja G and Biemans, Rianne and Senden-Gijsbers, Birgit L.M.G and Losen, Mario and Van Limbergen, Evert J and Germeraad, Wilfred T.V and Neri, Dario and Dubois, Ludwig and Lambin, Philippe
Radiotherapy and oncology, ISSN 0167-8140, 2015, Volume 116, Issue 3, pp. 438 - 442
Hematology, Oncology and Palliative Medicine | ED-B | MHCI | Immunotherapy | Cancer | Drug Administration Schedule | Recombinant Fusion Proteins - pharmacology | Combined Modality Therapy | Antineoplastic Agents - administration & dosage | Mice, Inbred Strains | Fibronectins - metabolism | Histocompatibility Antigens Class I - metabolism | Immunity, Cellular - immunology | Animals | Neoplasms - immunology | Killer Cells, Natural - immunology | Radioimmunotherapy - methods | Neoplasms - radiotherapy | Antineoplastic Agents - pharmacology | Mice | Recombinant Fusion Proteins - administration & dosage | Disease Models, Animal | Killer cells | Radiotherapy | Analysis | Tumors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text New ways to image and target tumour hypoxia and its molecular responses
by Dubois, Ludwig J and Niemans, Raymon and van Kuijk, Simon J.A and Panth, Kranthi M and Parvathaneni, Nanda-Kumar and Peeters, Sarah G.J.A and Zegers, Catharina M.L and Rekers, Nicolle H and van Gisbergen, Marike W and Biemans, Rianne and Lieuwes, Natasja G and Spiegelberg, Linda and Yaromina, Ala and Winum, Jean-Yves and Vooijs, Marc and Lambin, Philippe
Radiotherapy and oncology, ISSN 0167-8140, 2015, Volume 116, Issue 3, pp. 352 - 357
Hematology, Oncology and Palliative Medicine | Therapy | Hypoxia | Carbonic anhydrase IX | Window-of-opportunity trial | Imaging | Hypoxia - physiopathology | Positron-Emission Tomography | Neoplasms - physiopathology | Hypoxia - diagnostic imaging | Neoplasms - diagnostic imaging | Humans | Tumors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Preclinical Assessment of Efficacy of Radiation Dose Painting Based on Intratumoral FDG-PET Uptake
by Trani, Daniela and Yaromina, Ala and Dubois, Ludwig and Granzier, Marlies and Peeters, Sarah G. J. A and Biemans, Rianne and Nalbantov, Georgi and Lieuwes, Natasja and Reniers, Brigitte and Troost, Esther E. G. C and Verhaegen, Frank and Lambin, Philippe
Clinical cancer research, ISSN 1078-0432, 12/2015, Volume 21, Issue 24, pp. 5511 - 5518
Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasms - metabolism | Rhabdomyosarcoma - diagnosis