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The Journal of antimicrobial chemotherapy, ISSN 0305-7453, 07/2019, Volume 74, Issue 10, pp. 2959 - 2964
External ventricular drainage (EVD) carries a high risk of ventriculitis, increasingly caused by MDR Gram-negative bacteria such as Escherichia coli and... 
Original Research
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, pp. e0176855 - e0176855
Targeting epigenetic changes in diffuse intrinsic pontine glioma (DIPG) may provide a novel treatment option for patients. This report demonstrates that sodium... 
HISTONE DEACETYLASE INHIBITOR | GLIOBLASTOMA | CARBOPLATIN | ACID | BRAIN-STEM GLIOMA | ACTIVATING ACVR1 MUTATIONS | MULTIDISCIPLINARY SCIENCES | LEUKEMIA-CELLS | PHASE-I | EXPRESSION | CONVECTION-ENHANCED DELIVERY | Cell Survival - drug effects | Adjuvants, Pharmaceutic - pharmacology | Apoptosis - drug effects | Humans | Cells, Cultured | Rats | Brain Stem Neoplasms - drug therapy | Hippocampus - drug effects | Anticonvulsants - pharmacology | Valproic Acid - pharmacology | Brain Stem Neoplasms - metabolism | Glioma - metabolism | Hippocampus - metabolism | Acetylation - drug effects | Animals | Drug Repositioning - methods | Cell Line, Tumor | Histone Deacetylase Inhibitors - pharmacology | Epigenesis, Genetic - drug effects | Glioma - drug therapy | Divalproex | Complications and side effects | Gliomas | Dosage and administration | Research | Drug therapy | Valproic acid | Slopes | Brain | Cell culture | Brain stem | Estrogens | Brain cancer | Radiation | Cytotoxicity | Cerebrospinal fluid | Cancer therapies | Blood | Anticancer properties | Proteins | Learning | Alterations | Blood-brain barrier | Surgery | Biocompatibility | Genetics | Diagnosis | Acetylation | Inhibition | Deoxyribonucleic acid--DNA | Medical research | Iodides | Lymphatic leukemia | Gene expression | Survival | Discrimination | Inhibitors | Sodium | Documents | Carboplatin | Mutation | Drugs | Surgical implants | Animal models | Chromatin | Drug delivery systems | Toxicity | Leukemia | Brain tumors | Clinical trials | Neurosurgery | Antiepileptic agents | Convection | Platinum | Modulation | DNA methylation | Children | Formulations | Effectiveness | Hematology | Buildings | Breast cancer | Pharmacology | Radiation therapy | Brain research | Cell death | Epigenetics | Skull | Genetic engineering | Annexin V | Methylation | Differentiation | Apoptosis | Cancer | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 35, Issue 29, pp. 8406 - 8415
Journal Article
Journal of Neuroscience Methods, ISSN 0165-0270, 02/2016, Volume 259, pp. 47 - 56
Intraparenchymal convection-enhanced delivery (CED) of therapeutics directly into the brain has long been endorsed as a medium through which meaningful... 
Catheter | Convection-enhanced delivery (CED) | Chronic | Optimisation | Intermittent | NEUROTROPHIC FACTOR | BIOCHEMICAL RESEARCH METHODS | BRAIN-STEM | INFUSION | NEUROSCIENCES | FLOW | MOLECULES | TRIAL | GDNF | PARKINSON-DISEASE | PERFUSION | Brain | Drug Delivery Systems - methods | Humans | Catheters | Convection | Drugs | Drug delivery systems | Analysis | Biomedical engineering | Vehicles | Brain tumors
Journal Article
Journal of Neuroscience Methods, ISSN 0165-0270, 10/2018, Volume 308, pp. 337 - 345
The design and use of convection-enhanced delivery catheters remains an active field as clinical trials have highlighted suboptimal distribution as a... 
Controlled reflux | CED | Recessed-step-catheter | DIPG | Convection-Enhanced Delivery | Parkinson’s disease | Parkinson's disease | CONTROLLED-TRIAL | GENE DELIVERY | MACROMOLECULES | DRUG-DELIVERY | NEUROTROPHIC FACTOR | TISSUE | BIOCHEMICAL RESEARCH METHODS | INFUSION | NEUROSCIENCES | TECHNICAL NOTE | NEURTURIN | PARKINSONS-DISEASE
Journal Article
Neuro-Oncology, ISSN 1522-8517, 10/2014, Volume 16, Issue Suppl 6, pp. vi5 - vi5
INTRODUCTION: The translational potential of convection-enhanced drug delivery (CED) for the treatment of high grade glioma (HGG) may be enhanced by the... 
Abstracts
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 36, pp. 9190 - 9200
Journal Article
Journal Article
Fluids and Barriers of the CNS, ISSN 2045-8118, 01/2012, Volume 9, Issue 1, pp. 2 - 2
Convection-enhanced delivery (CED), a direct method for drug delivery to the brain through intraparenchymal microcatheters, is a promising strategy for... 
Nanoparticles | Solutes | Dextrans | Convection-enhanced delivery | Macrophages | Perivascular | Drugs | Drug delivery systems | Usage | Clinical trials | Management | Health aspects | Vehicles | perivascular | dextrans | solutes | macrophages | nanoparticles
Journal Article