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Pain, ISSN 0304-3959, 07/2019, Volume 160, Issue 9, pp. 1989 - 2003
P2X4 is a ligand-gated ion channel implicated in neuropathic pain. Drug discovery efforts targeting P2X4 have been unsuccessful largely because of the... 
Journal Article
Pain, ISSN 0304-3959, 2008, Volume 139, Issue 1, pp. 225 - 236
Journal Article
Drug Discovery Today, ISSN 1359-6446, 08/2012, Volume 17, Issue 15-16, pp. 875 - 879
For many decades, there have been few novel therapies for pain, and the number of promising targets that have been genuinely validated in the clinic is small.... 
RHEUMATOID-ARTHRITIS | THERMAL HYPERALGESIA | CHRONIC PAIN | RAT | JOINT PAIN | PHARMACOLOGY & PHARMACY | NECROSIS-FACTOR-ALPHA | MICE | INTERLEUKIN-6 | TANEZUMAB | NERVE GROWTH-FACTOR | Analgesics - therapeutic use | Antibodies, Monoclonal - therapeutic use | Animals | Pain - drug therapy | Humans | Biological Products - therapeutic use | Analgesics
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P266 - P266
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P943 - P944
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 06/2018, Volume 28, Issue 10, p. 1892
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.bmcl.2018.03.091 A novel... 
Care and treatment | Pain | Analysis | Prostaglandins E | Arthritis | Drug discovery | Acetic acid | Organic acids
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P405 - P405
Journal Article
Journal of Pain, ISSN 1526-5900, 2008, Volume 9, Issue 7, pp. 580 - 587
Abstract The role of specific nicotinic receptor (nAChR) subtypes in antinociception has not been fully elucidated because of the lack, until recently, of... 
Anesthesia & Perioperative Care | Pain Medicine | mecamylamine | α | inflammatory pain | complete Freund adjuvant-induced hyperalgesia | Nicotinic acetylcholine receptor | methyllycaconitine
Journal Article
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 08/2010, Volume 20, Issue 15, pp. 4653 - 4656
Structure-activity relationships (SAR) of analogues of lead compound 1 were investigated and compound 16 was selected for further study in animal models of... 
Pain | SAR | P2X
Journal Article
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