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Clinical Infectious Diseases, ISSN 1058-4838, 2015, Volume 61, Issue 5, pp. 683 - 691
Background. Despite the proven efficacy of acyclovir (ACV) therapy, herpes simplex encephalitis (HSE) continues to cause substantial morbidity and mortality.... 
Encephalitis | Antiviral therapy | Valacyclovir | Acyclovir | Herpes simplex virus | ADULT PATIENTS | DIAGNOSIS | INFECTIOUS DISEASES | MULTICENTER | MANAGEMENT | COMBINATION THERAPY | MICROBIOLOGY | IMMUNOLOGY | CEREBROSPINAL-FLUID | herpes simplex virus | ACYCLOVIR THERAPY | POLYMERASE-CHAIN-REACTION | encephalitis | VIRUS-ENCEPHALITIS | acyclovir | CENTRAL-NERVOUS-SYSTEM | antiviral therapy | valacyclovir | Acyclovir - therapeutic use | Follow-Up Studies | Acyclovir - analogs & derivatives | Antiviral Agents - therapeutic use | Humans | Middle Aged | Valine - analogs & derivatives | Male | Encephalitis, Herpes Simplex - epidemiology | Valine - administration & dosage | Antiviral Agents - administration & dosage | Young Adult | Encephalitis, Herpes Simplex - physiopathology | Cognition Disorders | Adolescent | Aged, 80 and over | Encephalitis, Herpes Simplex - drug therapy | Quality of Life | Adult | Female | Valine - therapeutic use | Aged | Acyclovir - administration & dosage | Treatment outcome | Dosage and administration | Drug therapy | Analysis | and Commentaries | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Infektionsmedicin | Immunologi inom det medicinska området | Klinisk medicin | Mikrobiologi inom det medicinska området | Clinical Medicine | Microbiology in the medical area | Medicinska och farmaceutiska grundvetenskaper | Infectious Medicine | Immunology in the medical area
Journal Article
Journal of Neurology, ISSN 0340-5354, 2/2006, Volume 253, Issue 2, pp. 163 - 170
To study the occurrence of relapse of herpes simplex encephalitis (HSE) and to find out whether soluble activity markers in cerebrospinal fluid (CSF) indicate... 
Neurology | Neurosciences | soluble CD8 and interleukin–10 | Medicine & Public Health | cerebrospinal fluid | neurofilament protein | HSV–DNA | Neuroradiology | relapse of herpes simplex encephalitis | Soluble CD8 and interleukin-10 | HSV-DNA | Neurofilament protein | Relapse of herpes simplex encephalitis | Cerebrospinal fluid | SOLUBLE FAS | VIRUS | PROTEIN | CEREBROSPINAL-FLUID | CLINICAL NEUROLOGY | MENINGITIS | ACYCLOVIR | INTERFERON-GAMMA | NEURON-SPECIFIC ENOLASE | IMMUNE ACTIVATION | soluble CD8 and interleukin-10 | LYMPHOCYTES | Enzyme-Linked Immunosorbent Assay - methods | Recurrence | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Male | Encephalitis, Herpes Simplex - epidemiology | Herpes Simplex - genetics | Case-Control Studies | Incidence | Glial Fibrillary Acidic Protein - cerebrospinal fluid | RNA, Messenger - biosynthesis | Encephalitis, Herpes Simplex - physiopathology | Time Factors | Reverse Transcriptase Polymerase Chain Reaction - methods | Aged, 80 and over | Adult | Female | Retrospective Studies | Encephalitis, Herpes Simplex - cerebrospinal fluid | Phosphopyruvate Hydratase - cerebrospinal fluid | Cytokines - cerebrospinal fluid | Encephalitis, Herpes Simplex - pathology | Herpes Simplex - cerebrospinal fluid | Adolescent | Aged | Causes of | Care and treatment | Dosage and administration | Diagnosis | Interleukin-10 | Herpes simplex encephalitis | pathology | RNA | methods | MEDICIN OCH HÄLSOVETENSKAP | 80 and over | Herpes Simplex | Glial Fibrillary Acidic Protein | epidemiology | genetics | biosynthesis | MEDICAL AND HEALTH SCIENCES | Encephalitis | Cytokines | Enzyme-Linked Immunosorbent Assay | Phosphopyruvate Hydratase | Messenger | Reverse Transcriptase Polymerase Chain Reaction | physiopathology
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0155832
Herpes simplex encephalitis (HSE) is a rare complication of Herpes simplex virus type-1 infection. It results in severe parenchymal damage in the brain.... 
BRAIN-BARRIER PERMEABILITY | POLYMERASE-CHAIN-REACTION | PROTECTION | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | RESISTANCE | CENTRAL-NERVOUS-SYSTEM | EXPRESSION | LOCUS | VIRUS TYPE-1 | DEFICIENCY | Rats, Inbred SHR | Animals | Quantitative Trait, Heritable | Chromosomes, Mammalian - genetics | Humans | Rats | Encephalitis, Herpes Simplex - genetics | Polymorphism, Single Nucleotide | von Willebrand Factor - genetics | Genotyping Techniques | Herpesvirus 1, Human | Von Willebrand factor | Physiological aspects | Genetic aspects | Single nucleotide polymorphisms | Research | Herpes simplex encephalitis | Risk factors | Brain | Neurosciences | Pathogenesis | Central nervous system | Herpes simplex | Viruses | Nervous system | Genomes | Infections | Single-nucleotide polymorphism | Tropical diseases | Ethics | Blood-brain barrier | Rodents | Chromosome 12 | Inbreeding | Physiology | Strains (organisms) | Recombinant | Linkage analysis | Encephalitis | Malaria | Asymptomatic infection | Environmental factors | Chromosome 4 | Permeability | Gene expression | Latency | Quantitative trait loci | Medicine | Genetic variance | Hospitals | Infectious diseases | von Willebrand factor gene | Genotyping | Herpes viruses | West Nile virus | Brain damage | VWF gene | Laboratory animals | Brain injury | Viral infections | Polymorphism | brain-barrier permeability | infection | expression | polymerase-chain-reaction | multiple-sclerosis | Infektionsmedicin | virus type-1 | Mikrobiologi inom det medicinska området | mice | cerebrospinal-fluid | Microbiology in the medical area | Infectious Medicine | locus | central-nervous-system
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 8, p. e12350
Herpes simplex encephalitis (HSE) is a rare disease with high mortality and significant morbidity among survivors. We have previously shown that susceptibility... 
ACTIVATION | VIRUS | RECOGNITION | FIBRILLARY ACIDIC PROTEIN | BIOLOGY | TLR9 | PROLIFERATION | SCHWANN-CELLS | EXPRESSION | DEFICIENCY | MOLECULES | Central Nervous System - metabolism | Encephalitis, Viral - virology | Species Specificity | Dendritic Cells - immunology | Humans | Central Nervous System - pathology | Peripheral Nerves - virology | Male | RNA, Messenger - metabolism | Virus Internalization | Histocompatibility Antigens Class I - metabolism | Signal Transduction - immunology | Herpesvirus 1, Human - physiology | Macrophages - virology | Time Factors | Inflammation Mediators - metabolism | Killer Cells, Natural - immunology | Histocompatibility Antigens Class II - metabolism | Encephalitis, Viral - metabolism | Peripheral Nerves - metabolism | Dendritic Cells - virology | Vibrissae - innervation | Central Nervous System - virology | Macrophages - immunology | Trigeminal Ganglion - pathology | Gene Expression Regulation - immunology | Killer Cells, Natural - virology | RNA, Messenger - genetics | Rats | Schwann Cells - pathology | Toll-Like Receptor 2 - metabolism | Immunity, Innate | Peripheral Nerves - pathology | Animals | Vibrissae - virology | Schwann Cells - virology | CD8-Positive T-Lymphocytes - virology | Kinetics | Trigeminal Ganglion - virology | CD8-Positive T-Lymphocytes - immunology | Toll-Like Receptor 9 - metabolism | Encephalitis, Viral - immunology | Immunohistochemistry | Herpes simplex | Encephalitis | Comparative analysis | Health aspects | Neurosciences | Brain stem | Central nervous system | Staining | Viruses | Infections | Cell adhesion & migration | Recruitment | Proteins | Genetic code | Phagocytes | Receptors | Cell growth | Immunology | Ischemia | Coding | Rodents | Toll-like receptors | Strains (organisms) | Immune system | Antigens | Gene expression | Morbidity | Ganglia | Hospitals | Infectious diseases | Molecular modelling | Microscopy | TLR2 protein | Herpes viruses | Trigeminal ganglion | schwann-cells | expression | proliferation | deficiency | molecules | recognition | tlr9 | MEDICIN OCH HÄLSOVETENSKAP | fibrillary acidic protein | activation | virus | MEDICAL AND HEALTH SCIENCES
Journal Article
PLoS Pathogens, ISSN 1553-7366, 06/2012, Volume 8, Issue 6, p. e1002753
Journal Article
Journal of Neurology, ISSN 0340-5354, 08/2009, Volume 256, Issue 8, pp. 1243 - 1251
Journal Article
International Journal of Tryptophan Research, ISSN 1178-6469, 11/2013, Volume 2013, Issue 6, p. 89
Herpes simplex virus (HSV) type 1 encephalitis (HSE) is a viral infectious disease with commonly occurring neurodegeneration and neurological/cognitive... 
Methyl aspartate | Encephalitis | Activities of daily living | Metabolites | Herpes simplex | Tryptophan | Comparative analysis | Health aspects | Herpes simplex virus | Neurologi | Klinisk medicin | Medicin och hälsovetenskap | Infektionsmedicin
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 09/2015, Volume 61, Issue 5, p. 683
  Despite the proven efficacy of acyclovir (ACV) therapy, herpes simplex encephalitis (HSE) continues to cause substantial morbidity and mortality. Among... 
Polymerase chain reaction | Encephalitis | Herpes viruses | Regression analysis | Antiviral drugs | Morbidity
Journal Article
Infection Ecology & Epidemiology, ISSN 2000-8686, 01/2011, Volume 1, Issue 1, p. 6029
Tick-borne encephalitis (TBE) is associated with higher morbidity and induces a stronger intrathecal immune activation than most other viral induced... 
tick-borne encephalitis | viral | cytokines | cerebrospinal fluid | pathophysiology
Journal Article
International Journal of Tryptophan Research, ISSN 1178-6469, 11/2013, Volume 2013, Issue 6, pp. 89 - 96
Journal Article
The Lancet, ISSN 0140-6736, 01/1991, Volume 337, Issue 8735, pp. 189 - 192
Journal Article