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Structure, ISSN 0969-2126, 2010, Volume 18, Issue 3, pp. 332 - 342
Interleukin-13 is a cytokine important for development of T helper cell type 2 (Th2) responses and plays a critical role in asthma and allergy. The IL-13... 
PROTEINS | MOLIMMUNO
Journal Article
Immunity, ISSN 1074-7613, 05/2015, Volume 42, Issue 5, pp. 929 - 941
It has long been thought that clonal deletion efficiently removes almost all self-specific T cells from the peripheral repertoire. We found that self-peptide... 
CD8-Positive T-Lymphocytes - cytology | Clonal Deletion | Animals | Flow Cytometry | Antigenic Variation | Self Tolerance - immunology | Humans | Female | Male | Mice | CD8-Positive T-Lymphocytes - immunology | Receptors, Antigen, T-Cell, alpha-beta - genetics
Journal Article
STRUCTURE, ISSN 0969-2126, 03/2010, Volume 18, Issue 3, pp. 332 - 342
Interleukin-13 is a cytokine important for development of T helper cell type 2 (Th2) responses and plays a critical role in asthma and allergy. The IL-13... 
SYSTEM | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR ALPHA-2 CHAIN | SOFTWARE | CELL BIOLOGY | IMMUNE | BIOPHYSICS | CLONING | INTERLEUKIN (IL)-13 RESPONSES | COMPONENT | BINDING | EXPRESSION | SUBUNIT | Antagonists
Journal Article
Bioinformatics, ISSN 1367-4803, 04/2019, Volume 35, Issue 8, pp. 1318 - 1325
Abstract Motivation The study of T cell receptor (TCR) repertoires has generated new insights into immune system recognition. However, the ability to robustly... 
ALPHA | CHAINS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EXPRESSION | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY
Journal Article
IMMUNITY, ISSN 1074-7613, 05/2015, Volume 42, Issue 5, pp. 929 - 941
It has long been thought that clonal deletion efficiently removes almost all self-specific T cells from the peripheral repertoire. We found that self-peptide... 
RECOGNITION | AUTOIMMUNITY | CELL REPERTOIRE | THYMIC SELECTION | TOLERANCE | RECEPTOR TRANSGENIC MICE | INSULIN EPITOPE | NEGATIVE SELECTION | PRECURSOR FREQUENCIES | IMMUNOLOGY | ANTIGEN RECEPTOR
Journal Article
Nature Biotechnology, ISSN 1087-0156, 2017, Volume 35, Issue 12, pp. 1145 - 1146
T-cell receptors with higher affinity for tumor antigens are discovered by harnessing T-cell development. 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DISPLAY | Antigen receptors, T cell | Receptors | Cell development (Biology) | Properties | Observations | T cells | Lymphocytes T
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 04/2008, Volume 130, Issue 14, pp. 4646 - 4659
The DNA-templated polymerization of synthetic building blocks provides a potential route to the laboratory evolution of sequence-defined polymers with... 
MOLECULAR REPLICATION | CATALYSIS | PNA | STRATEGY | IN-VITRO SELECTION | RNA-POLYMERASE MODEL | DERIVATIVES | EFFICIENT | CHEMISTRY, MULTIDISCIPLINARY | OLIGOMERS | OLIGONUCLEOTIDES | Lysine | Analysis | DNA | Polymerization | Chemical properties | Research | Aldehydes | Structure
Journal Article
Immunity, ISSN 1074-7613, 2011, Volume 35, Issue 5, pp. 681 - 693
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2018, Volume 115, Issue 31, p. E7369
T cell receptors (TCRs) bind to peptide-major histocompatibility complex (pMHC) with low affinity (Kd ∼ μM), which is generally assumed to facilitate... 
Bioengineering | Stress analysis | Yeast | Peptides | Cross-reactivity | Amino acids | T cell receptors | Lymphocytes T | Crystallography | Proteins | T-cell receptor | Receptors | Major histocompatibility complex | Reactivity | Lymphocytes | Affinity | Ligands | Histocompatibility | Crystal structure
Journal Article