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index medicus (34) 34
animals (24) 24
mice (23) 23
insulin (19) 19
endocrinology & metabolism (18) 18
insulin resistance (18) 18
humans (17) 17
male (17) 17
muscle, skeletal - metabolism (17) 17
obesity (15) 15
phosphorylation (15) 15
metabolism (14) 14
glucose - metabolism (12) 12
signal transduction (12) 12
abridged index medicus (11) 11
research (11) 11
glucose (10) 10
muscles (10) 10
physiological aspects (10) 10
mice, knockout (9) 9
rodents (9) 9
type 2 diabetes (9) 9
biochemistry & molecular biology (8) 8
diabetes (8) 8
gene expression (8) 8
liver (8) 8
musculoskeletal system (8) 8
physiology (8) 8
protein kinases (8) 8
skeletal muscle (8) 8
insulin - pharmacology (7) 7
adipose tissue (6) 6
diabetes mellitus, type 2 - metabolism (6) 6
energy metabolism (6) 6
female (6) 6
homeostasis (6) 6
insulin - metabolism (6) 6
insulin-resistance (6) 6
mice, inbred c57bl (6) 6
middle aged (6) 6
obesity - metabolism (6) 6
amp-activated protein kinases - genetics (5) 5
amp-activated protein kinases - metabolism (5) 5
analysis (5) 5
body-weight (5) 5
cell biology (5) 5
diet-induced obesity (5) 5
exercise (5) 5
gene-expression (5) 5
glucose-transport (5) 5
insulin - blood (5) 5
kinases (5) 5
leptin (5) 5
lipid metabolism (5) 5
medical and health sciences (5) 5
medicin och hälsovetenskap (5) 5
mellitus (5) 5
mice, obese (5) 5
muscle, skeletal - drug effects (5) 5
niddm subjects (5) 5
phosphatidylinositol 3-kinase activity (5) 5
phosphatidylinositol 3-kinases - metabolism (5) 5
phosphoinositide 3-kinase (5) 5
phosphorylation - drug effects (5) 5
proteins (5) 5
proto-oncogene proteins - metabolism (5) 5
receptors, leptin (5) 5
signal transduction - physiology (5) 5
activated protein-kinase (4) 4
animal models (4) 4
arcuate nucleus (4) 4
biological transport (4) 4
biological transport - drug effects (4) 4
blood glucose - metabolism (4) 4
diabetes mellitus, type 2 - genetics (4) 4
glucose clamp technique (4) 4
glycogen-synthase (4) 4
insulin receptor substrate proteins (4) 4
leptin - metabolism (4) 4
leptin - physiology (4) 4
liver - metabolism (4) 4
mice, transgenic (4) 4
mitochondria (4) 4
mutation (4) 4
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phosphatidylinositol 3-kinase (4) 4
phosphoproteins - metabolism (4) 4
proto-oncogene proteins c-akt (4) 4
rats (4) 4
resistance (4) 4
transport (4) 4
activation (3) 3
adenosine triphosphatase (3) 3
aminoimidazole carboxamide - analogs & derivatives (3) 3
aminoimidazole carboxamide - pharmacology (3) 3
animal-models (3) 3
biology (3) 3
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PLoS Medicine, ISSN 1549-1277, 05/2007, Volume 4, Issue 5, pp. 0868 - 0879
Background Type 2 diabetes mellitus ( T2DM) is characterized by defects in insulin secretion and action. Impaired glucose uptake in skeletal muscle is believed... 
MEDICINE, GENERAL & INTERNAL | HYPERGLYCEMIA | SKELETAL-MUSCLE CELLS | INSULIN-RESISTANCE | THIOREDOXIN-INTERACTING PROTEIN | MICE | DIFFERENTIATION | IDENTIFICATION | EXPRESSION | ASSOCIATION | DIABETES-SUSCEPTIBILITY GENES | Diabetes Mellitus, Type 2 - genetics | Humans | Qb-SNARE Proteins - genetics | Adipocytes - cytology | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Polymerase Chain Reaction | Carrier Proteins - physiology | Insulin - pharmacology | Genetic Predisposition to Disease | Glucose Intolerance - genetics | Cells, Cultured | Gene Expression Regulation - physiology | DNA-Binding Proteins - genetics | Hypoglycemic Agents - pharmacology | Linkage Disequilibrium | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Diabetes Mellitus, Type 2 - physiopathology | Promoter Regions, Genetic - physiology | Homeostasis - physiology | Protein Array Analysis | Blood Glucose - genetics | Polymorphism, Single Nucleotide | Glucose Clamp Technique | Muscle, Skeletal - pathology | Blood Glucose - metabolism | Proto-Oncogene Proteins c-bcl-6 | Proteins | Glucose metabolism | Medical research | Medicine, Experimental | Gene expression | Observations | Health aspects | Index Medicus | Nutrition and Metabolism | Genetics and Genomics | Genetics | Physiology | Diabetes | Diabetes and Endocrinology | Endocrinology | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
Journal Article
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 09/2015, Volume 309, Issue 7, pp. E679 - E690
AMP-activated protein kinase (AMPK) is a major sensor of energy homeostasis and stimulates ATP-generating processes such as lipid oxidation and glycolysis in... 
AMP-activated protein kinase | Metabolism | Skeletal muscle | skeletal muscle | metabolism
Journal Article
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 05/2017, Volume 58, Issue 5, pp. 907 - 915
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2018, Volume 115, Issue 9, pp. E2048 - E2057
Journal Article
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 08/2012, Volume 303, Issue 4, pp. E524 - E533
Szekeres F, Chadt A, Tom RZ, Deshmukh AS, Chibalin AV, Bjornholm M, Al-Hasani H, Zierath JR. The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle... 
Insulin resistance | Glucose transport | Glucose transporter 4 | Adenosine 5′-monophosphate-activated protein kinase | glucose transport | PHYSIOLOGY | AS160 | PHOSPHORYLATION | glucose transporter 4 | ACETYL-COA CARBOXYLASE | AKT SUBSTRATE | TRANSPORT | CONTRACTION | GLUT4 TRANSLOCATION | INSULIN-RESISTANCE | 14-3-3 BINDING | ENDOCRINOLOGY & METABOLISM | adenosine 5 '-monophosphate-activated protein kinase | insulin resistance | KINASE ACTIVATION | Deoxyglucose - metabolism | Gluconeogenesis - drug effects | Male | Muscle, Skeletal - metabolism | GTPase-Activating Proteins - metabolism | Glucose Transporter Type 4 - analysis | Insulin - blood | Aminoimidazole Carboxamide - pharmacology | Ribonucleotides - pharmacology | Liver - drug effects | Fasting - blood | Muscle, Skeletal - drug effects | Biological Transport - drug effects | Fasting - metabolism | Nuclear Proteins - genetics | Insulin - pharmacology | Glucose Tolerance Test | Liver - metabolism | Nuclear Proteins - metabolism | Hypoglycemic Agents - pharmacology | Gluconeogenesis - physiology | Animals | Aminoimidazole Carboxamide - analogs & derivatives | Signal Transduction - drug effects | Muscle Contraction - drug effects | Glucose - metabolism | Mice | Muscles | Glucose metabolism | Protein research | Observations | Analysis | Proteins | Musculoskeletal system | Liver | Rodents | Glucose | Metabolism | Insulin | Index Medicus | Basic Medicine | Physiology | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Fysiologi
Journal Article
eLife, ISSN 2050-084X, 2014, Volume 3, pp. e03245 - e03245
Obesity is associated with blunted beta-adrenoreceptor (beta-AR)-mediated lipolysis and lipid oxidation in adipose tissue, but the mechanisms linking nutrient... 
adipose tissue | TGF-beta | chemical-genetic | beta-adrenergic | lipolysis | obesity | NERVOUS-SYSTEM | METABOLIC SYNDROME | ACTIVATED RECEPTOR-GAMMA | SMAD PROTEINS | INHIBIN BETA-B | MITOCHONDRIAL BIOGENESIS | INSULIN-RESISTANCE | BIOLOGY | DOWN-REGULATION | DIET-INDUCED OBESITY | ADIPOSE-TISSUE | Activin Receptors, Type I - antagonists & inhibitors | Lipolysis - drug effects | Catecholamines - metabolism | Humans | Obesity - genetics | Adipose Tissue - metabolism | Adenosine Triphosphate - antagonists & inhibitors | Adenosine Triphosphate - metabolism | Diet, High-Fat | Lipid Peroxidation - drug effects | Obesity - etiology | Receptors, Adrenergic, beta - metabolism | Pyrazoles - pharmacology | Dietary Fats - adverse effects | Signal Transduction | Activin Receptors, Type I - deficiency | Adipose Tissue - pathology | Gene Expression Regulation | Pyrimidines - pharmacology | Activin Receptors, Type I - genetics | Adipocytes - pathology | Mice, Knockout | Obesity - pathology | Mitochondrial Turnover - drug effects | Animals | Receptors, Adrenergic, beta - genetics | Transforming Growth Factor beta - genetics | Adipocytes - metabolism | Obesity - prevention & control | Mice | Primary Cell Culture | Transforming Growth Factor beta - metabolism | Obesity | Nuclear magnetic resonance--NMR | Adipose tissue | Body fat | Lipid peroxidation | Energy expenditure | Nervous system | Adipocytes | Kinases | Insulin | Lipolysis | High fat diet | Mitochondria | Sodium | Plasmids | Rodents | Physiology | Oxidation | Adrenergic receptors | Index Medicus
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 12/2009, Volume 297, Issue 6, pp. 1554 - 1566
Journal Article