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Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 03/2006, Volume 316, Issue 3, pp. 1351 - 1359
Journal Article
Journal Article
International Journal of Neuropsychopharmacology, ISSN 1461-1457, 06/2013, Volume 16, Issue 5, pp. 1115 - 1127
The therapeutic effect of current antidepressant drugs appears after several weeks of treatment and a significant number of patients do not respond to... 
Antidepressant | dorsal raphe nucleus | SERT occupancy | A receptors | receptors | 5-HT | DRUG | PSYCHIATRY | FLUOXETINE | NEUROSCIENCES | MULTIMODAL COMPOUND | CLINICAL NEUROLOGY | IN-VITRO | 5-HT3 receptors | MEDIAL PREFRONTAL CORTEX | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | 5-HT1A receptors | LU AA21004 | GABAERGIC NEURONS | SEROTONERGIC NEURONS | REUPTAKE INHIBITOR
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 2006, Volume 112, Issue 3, pp. 612 - 629
Chronic insomnia affects a significant proportion of young adult and elderly populations. Treatment strategies should alleviate nighttime symptoms, the feeling... 
Sleep initiation and maintenance disorders | GABA A receptors | Selective extrasynaptic GABA agonist (SEGA) | Insomnia | Non-benzodiazepines | Slow wave activity (SWA) | 5-HT 2A/C antagonists | Slow wave sleep (SWS) | Benzodiazepine receptor agonists (BzRA) | Melatonin receptor agonists | Benzodiazepines | antagonists | receptors | GABA | 5-HT | GABOXADOL IMPROVES | benzodiazepines | slow wave activity (SWA) | selective extrasynaptic GABA agonist (SEGA) | sleep initiation and maintenance disorders | slow wave sleep (SWS) | SLOW-WAVE SLEEP | non-benzodiazepines | 5-HT-2(A/C) antagonists | NREM SLEEP | insomnia | GABA(A) receptors | PSYCHOMOTOR PERFORMANCE | RAMELTEON TAK-375 | VENTROLATERAL PREOPTIC NUCLEUS | MELATONIN AGONIST AGOMELATINE | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | benzodiazepine receptor agonists (BzRA) | CIRCADIAN REGULATION | melatonin receptor agonists | Sleep Initiation and Maintenance Disorders - etiology | Humans | Serotonin Antagonists - therapeutic use | Hypnotics and Sedatives - therapeutic use | Serotonin Antagonists - pharmacology | Sleep - drug effects | gamma-Aminobutyric Acid - physiology | GABA-A Receptor Agonists | Animals | Electroencephalography - drug effects | Receptors, Melatonin - agonists | Hypnotics and Sedatives - pharmacology | Sleep - physiology | Sleep Initiation and Maintenance Disorders - drug therapy | Antianxiety agents
Journal Article
Expert Opinion on Investigational Drugs, ISSN 1354-3784, 02/2009, Volume 18, Issue 2, pp. 109 - 123
The development of novel drugs falls into two completely different categories: truly novel drugs and drugs that can be considered as improvements of further... 
sleep | anxiety | pain | depression | Depression | Anxiety | Pain | Sleep | PHARMACOLOGY & PHARMACY | Pharmacology, Clinical - trends | Central Nervous System Agents | Mental Disorders - drug therapy | Drug Industry | Humans | Peripheral Nervous System Agents
Journal Article
European Neuropsychopharmacology, ISSN 0924-977X, 2012, Volume 23, Issue 2, pp. 133 - 145
Journal Article
BMC Psychiatry, ISSN 1471-244X, 11/2017, Volume 17, Issue 1, pp. 370 - 13
Background: The manifestation of major depressive disorder (MDD) may include cognitive symptoms that can precede the onset of MDD and persist beyond the... 
Canada | Qualitative study | China | Brazil | Cognitive symptoms | France | Germany | Major depressive disorder | VORTIOXETINE | PLACEBO | ANXIETY | PSYCHIATRY | IMPAIRMENT | ANTIDEPRESSANTS | DOUBLE-BLIND | WORK | QUALITY-OF-LIFE | DYSFUNCTION | LU AA21004 | Medical research | Care and treatment | Antidepressants | Medicine, Experimental | Health care industry | Cognition disorders
Journal Article