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index medicus (3) 3
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1. Full Text PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance
by Verma, Vivek and Shrimali, Rajeev K and Ahmad, Shamim and Dai, Winjie and Wang, Hua and Lu, Sumin and Nandre, Rahul and Gaur, Pankaj and Lopez, Jose and Sade-Feldman, Moshe and Yizhak, Keren and Bjorgaard, Stacey L and Flaherty, Keith T and Wargo, Jennifer A and Boland, Genevieve M and Sullivan, Ryan J and Getz, Gad and Hammond, Scott A and Tan, Ming and Qi, Jingjing and Wong, Phillip and Merghoub, Taha and Wolchok, Jedd and Hacohen, Nir and Janik, John E and Mkrtichyan, Mikayel and Gupta, Seema and Khleif, Samir N
Nature Immunology, ISSN 1529-2908, 09/2019, Volume 20, Issue 9, pp. 1231 - 1243
Understanding resistance to antibody to programmed cell death protein 1 (PD-1; anti-PD-1) is crucial for the development of reversal strategies. In... 
Antigens | Therapy | PD-1 protein | CD8 antigen | Antibodies | Reversing | Priming | T cell receptors | Lymphocytes T | Vaccines | Optimization | T-cell receptor | Cell death | Lymphocytes | CD38 antigen | Biomarkers | Tumors | Apoptosis
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2. Full Text Author Correction: PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance
by Verma, Vivek and Shrimali, Rajeev K and Ahmad, Shamim and Dai, Winjie and Wang, Hua and Lu, Sumin and Nandre, Rahul and Gaur, Pankaj and Lopez, Jose and Sade-Feldman, Moshe and Yizhak, Keren and Bjorgaard, Stacey L and Flaherty, Keith T and Wargo, Jennifer A and Boland, Genevieve M and Sullivan, Ryan J and Getz, Gad and Hammond, Scott A and Tan, Ming and Qi, Jingjing and Wong, Phillip and Merghoub, Taha and Wolchok, Jedd and Hacohen, Nir and Janik, John E and Mkrtichyan, Mikayel and Gupta, Seema and Khleif, Samir N
Nature Immunology, ISSN 1529-2908, 11/2019, Volume 20, Issue 11, pp. 1555 - 1555
An amendment to this paper has been published and can be accessed via a link at the top of the paper. 
PD-1 protein | CD8 antigen
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3. Full Text Resistance to checkpoint blockade therapy through inactivation of antigen presentation
by Sade-Feldman, Moshe and Jiao, Yunxin J and Chen, Jonathan H and Rooney, Michael S and Barzily-Rokni, Michal and Eliane, Jean-Pierre and Bjorgaard, Stacey L and Hammond, Marc R and Vitzthum, Hans and Blackmon, Shauna M and Frederick, Dennie T and Hazar-Rethinam, Mehlika and Nadres, Brandon A and Van Seventer, Emily E and Shukla, Sachet A and Yizhak, Keren and Ray, John P and Rosebrock, Daniel and Livitz, Dimitri and Adalsteinsson, Viktor and Getz, Gad and Duncan, Lyn M and Li, Bo and Corcoran, Ryan B and Lawrence, Donald P and Stemmer-Rachamimov, Anat and Boland, Genevieve M and Landau, Dan A and Flaherty, Keith T and Sullivan, Ryan J and Hacohen, Nir
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1136 - 11
Treatment with immune checkpoint blockade (CPB) therapies often leads to prolonged responses in patients with metastatic melanoma, but the common mechanisms of... 
PLATFORM | METASTATIC MELANOMA | CTLA-4 BLOCKADE | PEMBROLIZUMAB | GENOMICS | PD-1 BLOCKADE | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | CANCER-IMMUNOTHERAPY | MUTATIONS | TUMORS | Humans | Mice, Inbred C57BL | Antibodies, Monoclonal - therapeutic use | Antigen Presentation - genetics | Melanoma - pathology | CTLA-4 Antigen - immunology | Loss of Heterozygosity | Mice, Knockout | Neoplasms, Experimental - pathology | Point Mutation | Drug Resistance, Neoplasm - genetics | Neoplasm Metastasis | Animals | Melanoma - genetics | Melanoma - drug therapy | Neoplasms, Experimental - genetics | Female | Antigen Presentation - drug effects | Programmed Cell Death 1 Receptor - immunology | Neoplasms, Experimental - drug therapy | Antibodies, Monoclonal - immunology | beta 2-Microglobulin - genetics | Drug Resistance, Neoplasm - drug effects | Antigen presentation | Deactivation | PD-1 protein | Melanoma | Metastasis | Inactivation | Patients | Metastases | Heterozygosity | CTLA-4 protein | Major histocompatibility complex | Immune checkpoint | Loss of heterozygosity | Mutation | Target acquisition
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4. Full Text PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1 + CD38 hi cells and anti-PD-1 resistance
by Verma, Vivek and Shrimali, Rajeev K and Ahmad, Shamim and Dai, Winjie and Wang, Hua and Lu, Sumin and Nandre, Rahul and Gaur, Pankaj and Lopez, Jose and Sade-Feldman, Moshe and Yizhak, Keren and Bjorgaard, Stacey L and Flaherty, Keith T and Wargo, Jennifer A and Boland, Genevieve M and Sullivan, Ryan J and Getz, Gad and Hammond, Scott A and Tan, Ming and Qi, Jingjing and Wong, Phillip and Merghoub, Taha and Wolchok, Jedd and Hacohen, Nir and Janik, John E and Mkrtichyan, Mikayel and Gupta, Seema and Khleif, Samir N
Nature immunology, 09/2019, Volume 20, Issue 9, p. 1231
Understanding resistance to antibody to programmed cell death protein 1 (PD-1; anti-PD-1) is crucial for the development of reversal strategies. In... 
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5. Full Text Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
by Sade-Feldman, Moshe and Yizhak, Keren and Bjorgaard, Stacey L and Ray, John P and de Boer, Carl G and Jenkins, Russell W and Lieb, David J and Chen, Jonathan H and Frederick, Dennie T and Barzily-Rokni, Michal and Freeman, Samuel S and Reuben, Alexandre and Hoover, Paul J and Villani, Alexandra-Chloé and Ivanova, Elena and Portell, Andrew and Lizotte, Patrick H and Aref, Amir R and Eliane, Jean-Pierre and Hammond, Marc R and Vitzthum, Hans and Blackmon, Shauna M and Li, Bo and Gopalakrishnan, Vancheswaran and Reddy, Sangeetha M and Cooper, Zachary A and Paweletz, Cloud P and Barbie, David A and Stemmer-Rachamimov, Anat and Flaherty, Keith T and Wargo, Jennifer A and Boland, Genevieve M and Sullivan, Ryan J and Getz, Gad and Hacohen, Nir
Cell, ISSN 0092-8674, 11/2018, Volume 175, Issue 4, pp. 998 - 1013.e20
Treatment of cancer has been revolutionized by immune checkpoint blockade therapies. Despite the high rate of response in advanced melanoma, the majority of... 
checkpoint blockade | CD8+ T cells | single-cell RNA-seq | cancer immunotherapy | TCF7 | T cells | CD8 | METASTATIC MELANOMA | CTLA-4 BLOCKADE | READ ALIGNMENT | RNA-SEQ | PD-1 BLOCKADE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-CELLS | CANCER-IMMUNOTHERAPY | CHRONIC VIRAL-INFECTION | ANTITUMOR-ACTIVITY | CLINICAL-RESPONSE | CELL BIOLOGY | Proteins | Care and treatment | RNA | Immunotherapy | Melanoma | Development and progression | Drug therapy | Cancer
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6. Full Text Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
by Sade-Feldman, Moshe and Yizhak, Keren and Bjorgaard, Stacey L and Ray, John P and de Boer, Carl G and Jenkins, Russell W and Lieb, David J and Chen, Jonathan H and Frederick, Dennie T and Barzily-Rokni, Michal and Freeman, Samuel S and Reuben, Alexandre and Hoover, Paul J and Villani, Alexandra-Chloé and Ivanova, Elena and Portell, Andrew and Lizotte, Patrick H and Aref, Amir R and Eliane, Jean-Pierre and Hammond, Marc R and Vitzthum, Hans and Blackmon, Shauna M and Li, Bo and Gopalakrishnan, Vancheswaran and Reddy, Sangeetha M and Cooper, Zachary A and Paweletz, Cloud P and Barbie, David A and Stemmer-Rachamimov, Anat and Flaherty, Keith T and Wargo, Jennifer A and Boland, Genevieve M and Sullivan, Ryan J and Getz, Gad and Hacohen, Nir
Cell, ISSN 0092-8674, 01/2019, Volume 176, Issue 1-2, pp. 404 - 404
BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY
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