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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 137, Issue 2, pp. 601 - 609.e8
Background Late allergic reactions are common in the course of allergen-specific immunotherapy and even occur with allergy vaccines with reduced IgE... 
Allergy and Immunology | Allergy | allergen | rBet v 1 fragments | cutaneous lymphocyte antigen | atopy patch testing | recombinant hypoallergens | late-phase reaction | birch pollen allergy | rBet v 1 | specific immunotherapy | CCR4 | T-cell proliferation | OMALIZUMAB | DERMATITIS | IGE | ALLERGEN-SPECIFIC IMMUNOTHERAPY | IMMUNOLOGY | BIRCH POLLEN ALLERGEN | RHINITIS | EPITOPE | SKIN | EXPRESSION | LYMPHOCYTES | Humans | Male | Hypersensitivity, Delayed - metabolism | Pollen - immunology | Hypersensitivity, Delayed - immunology | Rhinitis, Allergic, Seasonal - diagnosis | Rhinitis, Allergic, Seasonal - immunology | Dermatitis, Atopic - diagnosis | Young Adult | Lymphocyte Activation - immunology | Allergens - immunology | T-Lymphocytes - metabolism | Betula - adverse effects | T-Cell Antigen Receptor Specificity - immunology | Dermatitis, Atopic - immunology | Histamine Release | Hypersensitivity, Immediate - immunology | Adult | Female | Hypersensitivity, Delayed - diagnosis | Patch Tests | Hypersensitivity, Immediate - diagnosis | Antigens, Plant - immunology | Hypersensitivity, Immediate - metabolism | T-Lymphocytes - immunology | Dermatitis, Atopic - metabolism | Cytokines - biosynthesis | Medical colleges | Allergens | Immunotherapy | Immunoglobulin E | T cells | Allergic reaction | Medical research | Atopic dermatitis | Medicine, Experimental | Skin | Testing | Antigenic determinants | Studies | Cytokines | Lymphocytes | Clinical trials | Inflammation | Allergies | Quality of life | Asthma
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 135, Issue 5, pp. 1207 - 1217.e11
Background Grass pollen is one of the most important sources of respiratory allergies worldwide. Objective This study describes the development of a grass... 
Allergy and Immunology | allergen | Grass pollen allergy | recombinant allergen | recombinant hypoallergenic allergen derivative | peptide-carrier technology | allergen-specific immunotherapy | P 2 | RECOGNITION | IGE | BLOCKING ANTIBODIES | IMMUNOLOGY | IMMUNOGENICITY | ALLERGY | IMMUNOTHERAPY | EXTRACTS | PHLEUM-PRATENSE POLLEN | IMMUNOGLOBULIN-E | EPITOPES | Hepatitis B Surface Antigens - genetics | Recombinant Fusion Proteins - immunology | Recombinant Fusion Proteins - isolation & purification | Humans | Poaceae | Vaccines, Synthetic - immunology | Pollen - immunology | Immunoglobulin E - blood | Lymphocyte Activation - immunology | Immunoglobulin E - immunology | Lymphocytes - immunology | Allergens - immunology | Immunoglobulin G - immunology | Basophils - immunology | Inflammation Mediators - metabolism | Protein Engineering | Female | Disease Models, Animal | Hepatitis B Surface Antigens - chemistry | Lymphocytes - metabolism | Peptides - immunology | Vaccines, Subunit - immunology | Recombinant Fusion Proteins - chemistry | Rhinitis, Allergic, Seasonal - prevention & control | Animals | Protein Binding | Recombinant Fusion Proteins - genetics | Mice | Basophils - metabolism | Cytokines - biosynthesis | Allergy | Vaccines | Peptides | Allergic reaction | Proteins | Immunization | Cytokines | E coli | Pollen | Grasses | Patients | Allergies | Binding sites | Quality of life | SIT, Allergen-specific immunotherapy | CFA, Complete Freund adjuvant | Rhinitis, Sinusitis, and Upper Airway Disease | KLH, Keyhole limpet hemocyanin
Journal Article
Nature, ISSN 0028-0836, 10/2011, Volume 478, Issue 7370, pp. 524 - 528
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 2, pp. 435 - 443.e4
Background More than 50% of allergic patients have house dust mite (HDM) allergy. Group 1 and 2 allergens are the major HDM allergens. Objective We sought to... 
Allergy and Immunology | Allergy | allergen | house dust mite allergy | specific immunotherapy | recombinant hypoallergen | DER-P-1 | IGE-BINDING | FUTURE | IMMUNOLOGY | REDUCTION | MUTATION | RECOMBINANT ALLERGENS | EXPRESSION | ANTIGEN | Recombinant Fusion Proteins - immunology | Hypersensitivity - prevention & control | Escherichia coli | Humans | Vaccination | Hypersensitivity - immunology | Male | Vaccines - therapeutic use | Antigens, Dermatophagoides - immunology | Immunoglobulin E - immunology | Immunoglobulin G - immunology | Cloning, Molecular | Female | Epitopes, T-Lymphocyte - immunology | Rabbits | Immunoglobulin E - metabolism | Vaccines - immunology | Vaccines, Combined | Antigens, Dermatophagoides - genetics | Arthropod Proteins - genetics | Arthropod Proteins - immunology | Pyroglyphidae - genetics | Vaccines - genetics | Animals | Cysteine Endopeptidases - genetics | Protein Binding | Recombinant Fusion Proteins - genetics | Vaccines, Synthetic | Mice | Cysteine Endopeptidases - immunology | Immunoglobulin G - metabolism | Pyroglyphidae - immunology | Allergens | Medical colleges | Immunotherapy | Children | Universities and colleges | Vaccines | Drug therapy | Allergic reaction | Health aspects | Proteins | Immunization | Peptides | Amino acids | Patients | Allergies | Molecular weight | Cysteine | Disulfide bonds | Hybrids | Hypersensitivity | Immunoglobulin G | Immunoglobulin E | Inflammation | Lymphocytes T | Epitopes | Immunological tolerance | Affinity chromatography | Der p 1 antigen | C.D | Leukocytes (basophilic)
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, p. e29925
The phosphoinositide 3-kinase (PI3-kinase) and the mammalian target of rapamycin (mTOR) are two major signaling molecules involved in growth and activation of... 
SURVIVAL | HUMAN-BLOOD BASOPHILS | FC-EPSILON-RI | MASTOCYTOSIS | TYROSINE KINASE | MULTIDISCIPLINARY SCIENCES | C-KIT | RECEPTOR | RECOMBINANT ALLERGENS | HISTAMINE-RELEASE | EXPRESSION | Humans | Middle Aged | Male | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Quinolines - pharmacology | TOR Serine-Threonine Kinases - antagonists & inhibitors | Immunoglobulin E - immunology | Basophils - immunology | Aged, 80 and over | Adult | Female | Basophils - drug effects | Mast Cells - immunology | Molecular Targeted Therapy - adverse effects | Imidazoles - adverse effects | Immunoglobulin E - metabolism | Immunoglobulin E - pharmacology | Imidazoles - pharmacology | Down-Regulation - drug effects | Mast Cells - drug effects | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cell Line, Tumor | Aged | Cell Proliferation - drug effects | Mice | Immunoglobulin E - physiology | Antibody-Dependent Cell Cytotoxicity - drug effects | Quinolines - adverse effects | Immunoglobulin E | Histamine | Growth | Apoptosis | TOR protein | Allergens | Thoracic surgery | Laboratories | Leukemia | Oncology | Activation | Thymidine | Kinases | Veterinary medicine | Signal transduction | Cell activation | Immunology | Xenografts | Bone marrow | Drug dosages | Internal medicine | Hematology | CD63 antigen | Pharmacology | Rapamycin | Allergies | 1-Phosphatidylinositol 3-kinase | Signaling | Infectious diseases | Stem cells | Ligands | Mast cells | Leukocytes (basophilic) | Cancer
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 490 - 493.e11
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2013, Volume 190, Issue 7, pp. 3068 - 3078
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 01/2015, Volume 135, Issue 1, pp. 102 - 109
Journal Article
The Plant Journal, ISSN 0960-7412, 05/2011, Volume 66, Issue 3, pp. 528 - 540
Summary To understand molecular processes in living plant cells, quantitative spectro‐microscopic technologies are required. By combining fluorescence lifetime... 
brassinosteroid‐insensitive 1 (BRI1) | brassinolide | fluorescence lifetime | P‐ATPase | cell wall | membrane potential | brassinosteroid-insensitive 1 (BRI1) | P-ATPase | STOMATAL GUARD-CELLS | MAIZE ROOT SEGMENTS | INTRACELLULAR PH | PLANT SCIENCES | GREEN FLUORESCENT PROTEIN | PROTEIN-PROTEIN INTERACTIONS | H+-ATPASE | ELECTROGENIC PROTON EXTRUSION | ABSCISIC-ACID | PLANT-GROWTH | PH-SENSITIVE GFP | Protein Kinases - metabolism | Arabidopsis - physiology | Phosphorylation | Sodium Acetate - pharmacology | Electrophysiology | Cell Membrane - physiology | Cell Wall - physiology | Recombinant Fusion Proteins - metabolism | Seedlings - growth & development | Arabidopsis Proteins - metabolism | Cell Wall - drug effects | Tobacco - physiology | Steroids, Heterocyclic - pharmacology | Green Fluorescent Proteins - metabolism | Plants, Genetically Modified - physiology | Arabidopsis - drug effects | Plants, Genetically Modified - genetics | Plants, Genetically Modified - drug effects | 2,4-Dichlorophenoxyacetic Acid - pharmacology | Tobacco - drug effects | Brassinosteroids | Seedlings - drug effects | Arabidopsis - genetics | Cholestanols - pharmacology | Cell Membrane - enzymology | Membrane Potentials | Seedlings - physiology | Adenosine Triphosphatases | Tobacco - genetics | Arabidopsis thaliana | Fluorescence | Cell membranes | Universities and colleges | Analysis | Plant biology | Plasma | Membranes | Flowers & plants | Cellular biology
Journal Article