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humans (80) 80
science & technology (78) 78
life sciences & biomedicine (77) 77
male (54) 54
female (53) 53
abridged index medicus (52) 52
cardiac & cardiovascular systems (52) 52
cardiovascular system & cardiology (52) 52
middle aged (50) 50
aged (47) 47
biological and medical sciences (34) 34
treatment outcome (33) 33
medical sciences (30) 30
cholesterol (28) 28
coronary heart disease (28) 28
heart (27) 27
statins (27) 27
cardiology. vascular system (25) 25
hydroxymethylglutaryl-coa reductase inhibitors - therapeutic use (24) 24
drug therapy (22) 22
risk factors (22) 22
double-blind method (21) 21
cardiovascular (20) 20
simvastatin - therapeutic use (20) 20
acute coronary syndromes (19) 19
drug therapy, combination (19) 19
simvastatin (19) 19
acute coronary syndrome - drug therapy (18) 18
ezetimibe (18) 18
cardiovascular disease (17) 17
care and treatment (16) 16
cholesterol, ldl - blood (16) 16
general & internal medicine (16) 16
anticholesteremic agents - therapeutic use (15) 15
cardiac patients (15) 15
clinical trials (15) 15
heart attacks (15) 15
medicine, general & internal (15) 15
analysis (14) 14
dosage and administration (14) 14
acute coronary syndrome (13) 13
lipids (13) 13
mortality (13) 13
simvastatin - administration & dosage (13) 13
adult (12) 12
health aspects (12) 12
follow-up studies (11) 11
internal medicine (11) 11
low density lipoproteins (11) 11
prognosis (11) 11
time factors (11) 11
acute coronary syndrome - blood (10) 10
cardiovascular diseases (10) 10
dose-response relationship, drug (10) 10
patients (10) 10
prospective studies (10) 10
research (10) 10
cardiology and cardiovascular medicine (9) 9
diabetes (9) 9
ezetimibe - therapeutic use (9) 9
heart failure (9) 9
hydroxymethylglutaryl-coa reductase inhibitors - adverse effects (9) 9
peripheral vascular disease (9) 9
prevention (9) 9
cardiology (8) 8
cardiovascular diseases - prevention & control (8) 8
clinical outcomes (8) 8
hypolipidemic agents - therapeutic use (8) 8
patient outcomes (8) 8
secondary prevention (8) 8
stroke (8) 8
tyrosine - analogs & derivatives (8) 8
usage (8) 8
angina pectoris (7) 7
animals (7) 7
anticholesteremic agents (7) 7
anticholesteremic agents - administration & dosage (7) 7
ezetimibe - administration & dosage (7) 7
general aspects (7) 7
heart attack (7) 7
hydroxymethylglutaryl-coa reductase inhibitors - administration & dosage (7) 7
risk (7) 7
tyrosine - therapeutic use (7) 7
acute coronary syndrome - mortality (6) 6
aged, 80 and over (6) 6
anticholesteremic agents - adverse effects (6) 6
atherosclerosis (6) 6
atorvastatin calcium (6) 6
azetidines - therapeutic use (6) 6
c-reactive protein - analysis (6) 6
cancer (6) 6
cardiovascular agents (6) 6
cholesterol, ldl (6) 6
confidence intervals (6) 6
coronary artery bypass (6) 6
coronary disease - drug therapy (6) 6
fibrinolytic agents - therapeutic use (6) 6
incidence (6) 6
lipids - blood (6) 6
low-density lipoprotein cholesterol (6) 6
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1. Full Text Efficacy and Tolerability of Evolocumab vs Ezetimibe in Patients With Muscle-Related Statin Intolerance: The GAUSS-3 Randomized Clinical Trial
by Nissen, Steven E and Stroes, Erik and Dent-Acosta, Ricardo E and Rosenson, Robert S and Lehman, Sam J and Sattar, Naveed and Preiss, David and Bruckert, Eric and Ceška, Richard and Lepor, Norman and Ballantyne, Christie M and Gouni-Berthold, Ioanna and Elliott, Mary and Brennan, Danielle M and Wasserman, Scott M and Somaratne, Ransi and Scott, Rob and Stein, Evan A and GAUSS-3 Investigators and for the GAUSS-3 Investigators
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 04/2016, Volume 315, Issue 15, pp. 1580 - 1590
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Myalgia - blood | Myalgia - chemically induced | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Myositis - chemically induced | Hypercholesterolemia - drug therapy | Myositis - prevention & control | Time Factors | Adult | Cholesterol, LDL - blood | Female | Muscular Diseases - prevention & control | Ezetimibe - therapeutic use | Muscular Diseases - chemically induced | Atorvastatin Calcium - adverse effects | Hypercholesterolemia - blood | Myalgia - prevention & control | Creatine Kinase - blood | Double-Blind Method | Ezetimibe - adverse effects | Biomarkers - blood | Myositis - blood | Anticholesteremic Agents - adverse effects | Muscular Diseases - blood | Rhabdomyolysis - prevention & control | Cross-Over Studies | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Rhabdomyolysis - chemically induced | Rhabdomyolysis - blood | Clinical trials | Cholesterol, LDL | Usage | Care and treatment | Side effects | Muscular system | Comparative analysis | Drug therapy | Low density lipoprotein | Statins | Index Medicus | Abridged Index Medicus
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2. Full Text An update on the IMProved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design
by Califf, Robert M., MD and Lokhnygina, Yuliya, PhD and Cannon, Christopher P., MD and Stepanavage, Michael E., MS and McCabe, Carolyn H., BS and Musliner, Thomas A., MD and Pasternak, Richard C., MD and Blazing, Michael A., MD and Giugliano, Robert P., MD, SM and Harrington, Robert A., MD and Braunwald, Eugene, MD
The American heart journal, ISSN 0002-8703, 2010, Volume 159, Issue 5, pp. 705 - 709
Cardiovascular | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Simvastatin - therapeutic use | Humans | Treatment Outcome | Models, Statistical | Acute Coronary Syndrome - blood | Acute Coronary Syndrome - drug therapy | Azetidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Cholesterol, LDL - blood | Ezetimibe, Simvastatin Drug Combination | Patient Compliance | Research Design | Drug Combinations | Studies | Nonprofit organizations | Bias | Lipids | Drug therapy | Pharmaceutical industry | Acute coronary syndromes | Patients | Cholesterol | Index Medicus | Abridged Index Medicus
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3. Full Text Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials
by Armitage, Jane and Baigent, Colin and Barnes, Elizabeth and Betteridge, D John and Blackwell, Lisa and Blazing, Michael and Bowman, Louise and Braunwald, Eugene and Byington, Robert and Cannon, Christopher and Clearfield, Michael and Colhoun, Helen and Collins, Rory and Dahlöf, Björn and Davies, Kelly and Davis, Barry and de Lemos, James and Downs, John R and Durrington, Paul and Emberson, Jonathan and Fellström, Bengt and Flather, Marcus and Ford, Ian and Franzosi, Maria Grazia and Fulcher, Jordan and Fuller, John and Furberg, Curt and Gordon, David and Goto, Shinya and Gotto, Antonio and Halls, Heather and Harper, Charlie and Hawkins, C Morton and Herrington, Will and Hitman, Graham and Holdaas, Hallvard and Holland, Lisa and Jardine, Alan and Jukema, J Wouter and Kastelein, John and Kean, Sharon and Keech, Anthony and Kirby, Adrienne and Kjekshus, John and Knatterud (deceased), Genell and Knopp (deceased), Robert and Koenig, Wolfgang and Koren, Michael and Krane, Vera and Landray, Martin J and LaRosa, John and Lonn, Eva and MacFarlane, Peter and MacMahon, Stephen and Maggioni, Aldo and Marchioli, Roberto and Marschner, Ian and Mihaylova, Borislava and Moyé, Lemuel and Murphy, Sabina and Nakamura, Haruo and Neil, Andrew and Newman, Connie and O'Connell, Rachel and Packard, Chris and Parish, Sarah and Pedersen, Terje and Peto, Richard and Pfeffer, Marc and Poulter, Neil and Preiss, David and Reith, Christina and Ridker, Paul and Robertson, Michele and Sacks, Frank and Sattar, Naveed and Schmieder, Roland and Serruys, Patrick and Sever, Peter and Shaw, John and Shear, Charles and Simes, John and Sleight, Peter and Spata, Enti and Tavazzi, Luigi and Tobert, Jonathan and Tognoni, Gianni and Tonkin, Andrew and Trompet, Stella and Varigos, John and Wanner, Christoph and Wedel, Hans and White, Harvey and Wikstrand, John and Wilhelmsen, Lars and Wilson, Kate and Young, Robin and Yusuf, Salim and Zannad, Faiez and Cholesterol Treatment Trialists' Collaboration and Cholesterol Treatment Trialists Co
The Lancet (British edition), ISSN 0140-6736, 02/2019, Volume 393, Issue 10170, pp. 407 - 415
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Aged | Age Factors | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Randomized Controlled Trials as Topic | Blood circulation disorders | Coronary artery bypass | Analysis | Cardiac patients | Low density lipoproteins | Trans fatty acids | Statins | Cardiovascular agents | Heart | Lipoproteins (low density) | Clinical trials | Risk | Evidence-based medicine | Incidence | Heterogeneity | Randomization | Reduction | Vascular diseases | Older people | Patient safety | Safety | Heart diseases | Age | Medical research | Stroke | Data analysis | Statistical analysis | Mortality | Patients | Disease control | Cholesterol | Meta-analysis | Renal failure | Dialysis | Health risk assessment | Cancer | Index Medicus | Abridged Index Medicus
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4. Full Text A care pathway for the cardiovascular complications of COVID-19: Insights from an institutional response
by Loungani, Rahul S and Rehorn, Michael R and Newby, L. Kristin and Katz, Jason N and Klem, Igor and Mentz, Robert J and Jones, W. Schuyler and Vemulapalli, Sreekanth and Kelsey, Anita M and Blazing, Michael A and Piccini, Jonathan P and Patel, Manesh R
The American heart journal, ISSN 0002-8703, 07/2020, Volume 225, pp. 3 - 9
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Critical Pathways - organization & administration | Pandemics | United States | Humans | Heart Failure - physiopathology | Coronavirus Infections - physiopathology | Patient Care Management - methods | Infection Control - methods | Arrhythmias, Cardiac - physiopathology | Heart Diseases - virology | COVID-19 | Heart Failure - therapy | Infection Control - organization & administration | SARS-CoV-2 | Coronavirus Infections - epidemiology | Pneumonia, Viral - epidemiology | Pneumonia, Viral - complications | Coronavirus Infections - complications | Heart Failure - diagnosis | Heart Failure - etiology | Arrhythmias, Cardiac - therapy | Betacoronavirus - isolation & purification | Heart Diseases - physiopathology | Pneumonia, Viral - therapy | Arrhythmias, Cardiac - etiology | Pneumonia, Viral - physiopathology | Heart Diseases - diagnosis | Heart Diseases - therapy | Coronavirus Infections - therapy | Evidence-Based Practice - trends | Arrhythmias, Cardiac - diagnosis | Critical Pathways - standards | Complications and side effects | Coronaviruses | Cardiology | Analysis | Severe acute respiratory syndrome | Cardiovascular system | Resource utilization | Medical imaging | Complications | Mortality | Viral diseases | Resource availability | Cardiovascular disease | Infections | Resources utilization | Severe acute respiratory syndrome coronavirus 2 | Respiratory diseases | Heart diseases | Index Medicus | Abridged Index Medicus
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5. Full Text LONG TERM SIGNIFICANCE OF HEART FAILURE COMPLICATING ACUTE MYOCARDIAL INFARCTION IN 11,185 PATIENTS FROM THE IMPROVED REDUCTION OF OUTCOMES: VYTORIN EFFICACY INTERNATIONAL TRIAL (IMPROVE-IT)
by Silverman, Michael G and Cannon, Christopher and Blazing, Michael and Mach, Francois and Zhou, Jing and Tershakovec, Andrew and Giugliano, Robert
Journal of the American College of Cardiology, ISSN 0735-1097, 2016, Volume 67, Issue 13, pp. 484 - 484
Cardiovascular | Internal Medicine | Heart failure | Patient outcomes | Cardiac patients | Heart attack | Long term | Heart attacks
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6. Full Text Atherothrombotic Risk Stratification and Ezetimibe for Secondary Prevention
by Bohula, Erin A., MD, DPhil and Morrow, David A., MD, MPH and Giugliano, Robert P., MD, SM and Blazing, Michael A., MD and He, Ping, MS and Park, Jeong-Gun, PhD and Murphy, Sabina A., MPH and White, Jennifer A., MS and Kesaniemi, Y. Antero, MD, PhD and Pedersen, Terje R., MD, PhD and Brady, Adrian J., MD and Mitchel, Yale, MD and Cannon, Christopher P., MD and Braunwald, Eugene, MD
Journal of the American College of Cardiology, ISSN 0735-1097, 2017, Volume 69, Issue 8, pp. 911 - 921
Cardiovascular | Internal Medicine | simvastatin | acute coronary syndrome | risk stratification | secondary prevention | ezetimibe | low-density lipoprotein cholesterol | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Simvastatin - therapeutic use | Prospective Studies | Risk Assessment | Humans | Middle Aged | Male | Treatment Outcome | Secondary Prevention | Acute Coronary Syndrome - complications | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Acute Coronary Syndrome - therapy | Female | Aged | Ezetimibe - therapeutic use | Myocardial Infarction - prevention & control | Medical colleges | Continuing medical education | Cardiology | Coronary heart disease | Medicine, Preventive | Statins | Cardiovascular agents | Preventive health services | Prevention | Medical research | Low density lipoproteins | Medicine, Experimental | Hypertension | Heart failure | Stroke | Heart attacks | Cardiovascular disease | Lipids | Angina pectoris | Low density lipoprotein | Patients | Cholesterol | Disease prevention | Coronary vessels | Electrocardiography | Population | Diabetes | Kidney diseases | Health risk assessment | Acute coronary syndromes | Age | Index Medicus | Abridged Index Medicus
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7. Full Text Evaluating cardiovascular event reduction with ezetimibe as an adjunct to simvastatin in 18,144 patients after acute coronary syndromes: Final baseline characteristics of the IMPROVE-IT study population
by Blazing, Michael A., MD and Giugliano, Robert P., MD, SM and Cannon, Christopher P., MD and Musliner, Thomas A., MD and Tershakovec, Andrew M., MD, MPH and White, Jennifer A., MS and Reist, Craig, PhD and McCagg, Amy, BS and Braunwald, Eugene, MD and Califf, Robert M., MD
The American heart journal, ISSN 0002-8703, 2014, Volume 168, Issue 2, pp. 205 - 212.e1
Cardiovascular | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Simvastatin - therapeutic use | Cardiovascular Diseases - drug therapy | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Ezetimibe | Cholesterol, LDL - drug effects | Male | Azetidines - pharmacology | Acute Coronary Syndrome - blood | Acute Coronary Syndrome - drug therapy | Acute Coronary Syndrome - complications | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Azetidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Cardiovascular Diseases - epidemiology | Cholesterol, LDL - blood | Female | Aged | Drug Therapy, Combination | Anticholesteremic Agents - pharmacology | Medical research | Low density lipoproteins | Simvastatin | Cardiac patients | Medicine, Experimental | Coronary heart disease | Antilipemic agents | Heart attacks | Acute coronary syndromes | Drug therapy | Cholesterol | Statins | Index Medicus | Abridged Index Medicus
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8. Full Text Splanchnic nerve block for decompensated chronic heart failure: splanchnic-HF
by Fudim, Marat and Fudim, Marat and Ganesh, Arun and Green, Cindy and Green, Cindy and Jones, W. Schuyler and Jones, W Schuyler and Blazing, Michael A and DeVore, Adam D and Felker, G Michael and Felker, G. Michael and Kiefer, Todd L and Kiefer, Todd L and Kong, David F and Kong, David F and Boortz-Marx, Richard L and Hernandez, Adrian F and Patel, Manesh R and Patel, Manesh R
European heart journal, ISSN 0195-668X, 12/2018, Volume 39, Issue 48, pp. 4255 - 4256
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Index Medicus | EHJ Brief Communication
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9. Full Text Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): Comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes
by Cannon, Christopher P., MD and Giugliano, Robert P., MD, SM and Blazing, Michael A., MD and Harrington, Robert A., MD and Peterson, John L., MD and Sisk, Christine McCrary, BS and Strony, John, MD and Musliner, Thomas A., MD and McCabe, Carolyn H., BS and Veltri, Enrico, MD and Braunwald, Eugene, MD and Califf, Robert M., MD and for the IMPROVE-IT Investigators and IMPROVE-IT Inves and IMPROVE-IT Investigators and Sahlgrenska akademin and Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin and Institute of Medicine, Department of Emergeny and Cardiovascular Medicine and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
The American heart journal, ISSN 0002-8703, 2008, Volume 156, Issue 5, pp. 826 - 832
Cardiovascular | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Heart | Biological and medical sciences | Myocarditis. Cardiomyopathies | Medical sciences | Coronary heart disease | Acute Coronary Syndrome - drug therapy | Simvastatin - therapeutic use | Multicenter Studies as Topic | Azetidines - therapeutic use | Double-Blind Method | Simvastatin - administration & dosage | Anticholesteremic Agents - administration & dosage | Humans | Treatment Outcome | Ezetimibe, Simvastatin Drug Combination | Drug Combinations | Care and treatment | Cardiac patients | Patient outcomes | Simvastatin | Low density lipoproteins | Clinical trials | Comparative analysis | Cholesterol | Heart attacks | Acute coronary syndromes | Drug therapy | Index Medicus | Abridged Index Medicus | MEDICIN OCH HÄLSOVETENSKAP | MEDICAL AND HEALTH SCIENCES
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10. Full Text Risk of Incident Diabetes With Intensive-Dose Compared With Moderate-Dose Statin Therapy: A Meta-analysis
by Preiss, David and Seshasai, Sreenivasa Rao Kondapally and Welsh, Paul and Murphy, Sabina A and Ho, Jennifer E and Waters, David D and DeMicco, David A and Barter, Philip and Cannon, Christopher P and Sabatine, Marc S and Braunwald, Eugene and Kastelein, John J. P and de Lemos, James A and Blazing, Michael A and Pedersen, Terje R and Tikkanen, Matti J and Sattar, Naveed and Ray, Kausik K
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 06/2011, Volume 305, Issue 24, pp. 2556 - 2564
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | General aspects | Diabetes. Impaired glucose tolerance | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Dose-Response Relationship, Drug | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Cardiovascular Diseases - prevention & control | Diabetes Mellitus - epidemiology | Humans | Cardiovascular Diseases - epidemiology | Risk | Odds Ratio | Randomized Controlled Trials as Topic | Clinical trials | Diabetes | Drug therapy | Drug dosages | Statins | Meta-analysis | Index Medicus | Abridged Index Medicus
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