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1. Full Text Opposing microRNA families regulate self-renewal in mouse embryonic stem cells
by Blelloch, Robert and Melton, Collin and Judson, Robert L
Nature, ISSN 0028-0836, 02/2010, Volume 463, Issue 7281, pp. 621 - 626
When embryonic stem cells (ESCs) differentiate, they must both silence the ESC self-renewal program and activate new tissue-specific programs. In the absence... 
SOMATIC-CELLS | DNA METHYLATION | RNA | URIDYLATION | LIN28 | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTIONAL NETWORK | INDUCED PLURIPOTENCY | C-MYC | DIFFERENTIATION | EXPRESSION | Embryonic Stem Cells - metabolism | RNA-Binding Proteins - genetics | Cell Proliferation | Embryonic Stem Cells - cytology | MicroRNAs - antagonists & inhibitors | Computational Biology | Gene Silencing | 3' Untranslated Regions - genetics | MicroRNAs - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Open Reading Frames - genetics | Proteins - genetics | Transcription Factors - metabolism | Animals | Genes, myc - genetics | Transcription, Genetic | Mice | MicroRNAs - genetics | Induced Pluripotent Stem Cells - cytology | Cell Dedifferentiation - genetics | Cellular Reprogramming - genetics | Cell Lineage - genetics | Induced Pluripotent Stem Cells - metabolism | Stem cell research | MicroRNA | Research | Embryonic stem cells | Genomics | Analysis | Evacuations & rescues | Cell cycle | Cancer | Index Medicus
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2. Full Text Embryonic stem cell-specific microRNAs promote induced pluripotency
by Venere, Monica and Blelloch, Robert and Judson, Robert L and Babiarz, Joshua E
Nature Biotechnology, ISSN 1087-0156, 05/2009, Volume 27, Issue 5, pp. 459 - 461
This report demonstrates that introduction of microRNAs (miRNAs) specific to embryonic stem cells enhances the production of mouse induced pluripotent stem... 
GENERATION | DNA METHYLATION | CLUSTER | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MOUSE | Pluripotent Stem Cells - metabolism | Embryonic Stem Cells - metabolism | Animals | Embryonic Stem Cells - cytology | Cell Dedifferentiation | MicroRNAs - metabolism | Mice | Proto-Oncogene Proteins c-myc - metabolism | Physiological aspects | Genetic aspects | Research | RNA | Embryonic stem cells | Gene expression | Biotechnology | Cellular biology | Ribonucleic acid--RNA | Rodents | Stem cells | Index Medicus
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3. Full Text Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells
by Lamouille, Samy and Judson, Robert L and Blelloch, Robert and Subramanyam, Deepa and Derynck, Rik and Liu, Jason Y and Bucay, Nathan
Nature Biotechnology, ISSN 1087-0156, 05/2011, Volume 29, Issue 5, pp. 443 - 448
The embryonic stem cell-specific cell cycle-regulating (ESCC) family of microRNAs (miRNAs) enhances reprogramming of mouse embryonic fibroblasts to induced... 
TRANSITION | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | STATE | GENERATION | MICRORNAS | EXPRESSION | DISCOVERY | Cell Line | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Epigenomics | Humans | MicroRNAs - metabolism | Keratinocytes - cytology | Blotting, Western | Gene Expression Regulation, Developmental | Keratinocytes - metabolism | Epithelial-Mesenchymal Transition | Polymerase Chain Reaction | Cell Differentiation | Fibroblasts - cytology | MicroRNAs - genetics | Induced Pluripotent Stem Cells - cytology | Transforming Growth Factor beta - metabolism | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Physiological aspects | Fibroblasts | Genetic aspects | MicroRNA | Research | Embryonic stem cells | Epigenetics | Kinetics | Cellular biology | Ribonucleic acid--RNA | Stem cells | Cell cycle | Index Medicus
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4. Full Text MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells
by Judson, Robert L and Greve, Tobias S and Parchem, Ronald J and Blelloch, Robert
Nature Structural and Molecular Biology, ISSN 1545-9993, 10/2013, Volume 20, Issue 10, pp. 1227 - 1237
Individual microRNAs (miRNAs) can target hundreds of mRNAs forming networks of presumably cooperating genes. To test this presumption, we functionally screened... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | IDENTIFICATION | CELL BIOLOGY | BIOPHYSICS | MAMMALIAN MICRORNAS | REPRESSION | MIR-302 | TARGETS | GENERATION | PROMOTES | EXPRESSION | REPROGRAMMING SOMATIC-CELLS | Fibroblasts - cytology | Mice | Animals | Pluripotent Stem Cells - cytology | MicroRNAs - physiology | Cell Differentiation - physiology | Fibroblasts | MicroRNA | Properties | Cell differentiation | Stem cells | Molecular biology | MicroRNAs | Index Medicus
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5. Full Text Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation
by Wang, Yangming and Blelloch, Robert and Baehner, Lauren and Baskerville, Scott and Shenoy, Archana and Babiarz, Joshua E
Nature Genetics, ISSN 1061-4036, 12/2008, Volume 40, Issue 12, pp. 1478 - 1483
Dgcr8 knockout embryonic stem (ES) cells lack microprocessor activity and hence all canonical microRNAs (miRNAs). These cells proliferate slowly and accumulate... 
DNA METHYLATION | BIOGENESIS | PATHWAY | GENES | GENETICS & HEREDITY | TARGETS | DIFFERENTIATION | DIVISION | CYCLE | Proteins - genetics | Animals | Cell Proliferation | Cell Cycle | Mice | MicroRNAs - genetics | Embryonic Stem Cells | RNA-Binding Proteins | Cell proliferation | RNA | Cell cycle | Physiological aspects | Genetic aspects | Research | Embryonic stem cells | Proteins | Cell growth | Mutation | Ribonucleic acid--RNA | Embryos | Stem cells | Index Medicus
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6. Full Text DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
by Blelloch, Robert and Medvid, Rostislav and Wang, Yangming and Jaenisch, Rudolf and Melton, Collin
Nature Genetics, ISSN 1061-4036, 03/2007, Volume 39, Issue 3, pp. 380 - 385
The molecular controls that govern the differentiation of embryonic stem (ES) cells remain poorly understood. DGCR8 is an RNA-binding protein that assists the... 
MICROPROCESSOR COMPLEX | NUCLEAR EXPORT | DICER | RNA | PATHWAY | GENETICS & HEREDITY | Embryonic Stem Cells - metabolism | Endoribonucleases - genetics | Embryonic Stem Cells - cytology | Ribonuclease III - metabolism | Endoribonucleases - metabolism | Cells, Cultured | MicroRNAs - metabolism | RNA-Binding Proteins | Mice, Knockout | Proteins - genetics | DEAD-box RNA Helicases - genetics | Phenotype | Animals | Proteins - metabolism | Mice | DEAD-box RNA Helicases - metabolism | Cell Differentiation - physiology | Physiological aspects | Cellular proteins | Embryonic stem cells | Enzymes | Genetic markers | Cellular biology | Ribonucleic acid | Rodents | Stem cells | Ribonucleic acid--RNA | Embryos | Index Medicus
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7. Full Text Let‐7 and miR‐125 cooperate to prime progenitors for astrogliogenesis
by Shenoy, Archana and Danial, Muhammad and Blelloch, Robert H
The EMBO Journal, ISSN 0261-4189, 05/2015, Volume 34, Issue 9, pp. 1180 - 1194
The molecular basis of astrocyte differentiation and maturation is poorly understood. As micro RNA s have important roles in cell fate transitions, we set out... 
Let‐7 | microRNAs | miR‐125 | differentiation | astrocytes | miR-125 | Let-7 | DEVELOPING SPINAL-CORD | DNA METHYLATION | MICRORNA BIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEAR RECEPTOR TLX | SELF-RENEWAL | PROLIFERATION | CELL BIOLOGY | OLIGODENDROCYTE DIFFERENTIATION | NEURAL STEM-CELLS | ES CELLS | RNA-Binding Proteins - genetics | Brain Neoplasms - pathology | STAT Transcription Factors - metabolism | Cell Survival - genetics | MicroRNAs - metabolism | Janus Kinases - metabolism | Glioma - genetics | Neuroglia - cytology | Glioma - pathology | 3' Untranslated Regions | Cell Differentiation - physiology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Astrocytes - cytology | Signal Transduction | Cells, Cultured | Gene Expression Regulation | Brain Neoplasms - genetics | Gene Knockout Techniques | Astrocytes - physiology | Animals | Stem Cells - physiology | Mice | MicroRNAs - genetics | RNA-Binding Proteins - metabolism | Gene expression | MicroRNAs | Stem cells | Index Medicus
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8. Full Text Two miRNA Clusters Reveal Alternative Paths in Late-Stage Reprogramming
by Parchem, Ronald J and Ye, Julia and Judson, Robert L and LaRussa, Marie F and Krishnakumar, Raga and Blelloch, Amy and Blelloch, Robert and Oldham, Michael C
Cell Stem Cell, ISSN 1934-5909, 05/2014, Volume 14, Issue 5, pp. 617 - 631
Ectopic expression of specific factors such as Oct4, Sox2, and Klf4 (OSK) is sufficient to reprogram somatic cells into induced pluripotent stem cells (iPSCs).... 
PLURIPOTENT STEM-CELLS | SOMATIC-CELLS | EMBRYONIC-DEVELOPMENT | DNA METHYLATION | GROUND-STATE | GENE | MOUSE EMBRYOS | SELF-RENEWAL | MICRORNAS | IPS CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Animals | Female | Male | MicroRNAs - metabolism | Mice | MicroRNAs - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Cellular Reprogramming - genetics | Cellular Reprogramming - physiology | Index Medicus
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9. Nutrition in industry
by Pett, Lionel Bradley and Goodhart, Robert Stanley, 1909 and Blelloch, David Habershon, 1896 and International Labour Office
1946, 1 p. l., ii, 177 p. incl. illus., tables, forms. diagrs. (1 fold.)
Nutrition | Food supply | Restaurants | Industrial welfare | World War, 1939-1945
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10. Full Text Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the autoregulation of Dgcr8
by Shenoy, Archana and Blelloch, Robert
PLoS ONE, 09/2009, Volume 4, Issue 9
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11. Full Text Biogenesis, delivery, and function of extracellular RNA
by Patton, James G and Franklin, Jeffrey L and Weaver, Alissa M and Vickers, Kasey and Zhang, Bing and Coffey, Robert J and Mark Ansel, K and Blelloch, Robert and Goga, Andrei and Huang, Bo and L'Etoille, Noelle and Raffai, Robert L and Lai, Charles P and Krichevsky, Anna M and Mateescu, Bogdan and Greiner, Vanille J and Hunter, Craig and Voinnet, Olivier and McManus, Michael T
Journal of Extracellular Vesicles, ISSN 2001-3078, 01/2015, Volume 4, Issue 1, pp. 27494 - 27494
The Extracellular RNA (exRNA) Communication Consortium was launched by the National Institutes of Health to focus on the extent to which RNA might function in... 
exRNA | ERCC | extracellular RNA | Extracellular RNA | ExRNA | Proteins | Consortia | Plasma | Animal communication | MicroRNAs | Biosynthesis | Gene expression | Exports
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12. Full Text miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN -amplified neuroblastoma
by Lim, Lionel and Haber, Michelle and Judson, Robert L and Norris, Murray D and Swarbrick, Alexander and Woods, Susan L and Hackett, Christopher S and Ashton, Lesley J and Shaw, Alexander and Blelloch, Robert and Preiss, Thomas and L'Etoile, Noelle and Nguyen, Akira and Huskey, Noelle and Chetcuti, Albert and Chanthery, Yvan and Goga, Andrei and Sullivan, Christopher S and Balakrishnan, Asha and Phua, Yuwei and Marcusson, Eric G and Lengyel, Peter and Weiss, William
Nature Medicine, ISSN 1078-8956, 10/2010, Volume 16, Issue 10, pp. 1134 - 1140
Inactivation of the p53 tumor suppressor pathway allows cell survival in times of stress and occurs in many human cancers; however, normal embryonic stem cells... 
MEDICINE, RESEARCH & EXPERIMENTAL | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAMMARY TUMORIGENESIS | RESTORATION | MODEL | CANCER | CELL BIOLOGY | INHIBITION | PATHWAY | IN-VIVO | EXPRESSION | MICRORNA | Oncogene Proteins - genetics | Tumor Suppressor Protein p53 - antagonists & inhibitors | Humans | Neuroblastoma - genetics | Mice, Transgenic | Tumor Suppressor Protein p53 - physiology | Animals | Gene Amplification | Female | Mice | Mice, Inbred BALB C | N-Myc Proto-Oncogene Protein | DNA Damage | MicroRNAs - physiology | 3' Untranslated Regions | Nuclear Proteins - genetics | Binding Sites | Neuroblastoma - pathology | Oncogenes | Apoptosis | Patient outcomes | Cancer cells | Physiological aspects | Development and progression | Tumor suppressor genes | Genetic aspects | Neuroblastoma | Properties | Gene expression | Neurosciences | Cellular biology | Stem cells | Cancer | Index Medicus
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