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genesis, ISSN 1526-954X, 12/2013, Volume 51, Issue 12, pp. 827 - 834
Summary Gene inactivation is an important tool for correlation of phenotypic and genomic data, allowing researchers to infer normal gene function based on the... 
gene targeting | zinc finger nucleases | gene knockouts | TALENs | CRISPR/Cas | Zinc finger nucleases | Gene targeting | Gene knockouts | Enzymes | Embryonic development | Analysis | Genes | Genomics | Genetic research | Zinc finger proteins | Amphibians | CRISPR | Cas
Journal Article
genesis, ISSN 1526-954X, 12/2013, Volume 51, Issue 12, pp. 827 - 834
Journal Article
Journal of Visualized Experiments, ISSN 1940-087X, 02/2018, Volume 2018, Issue 132
The creation of mutant lines by genome editing is accelerating genetic analysis in many organisms. CRISPR/Cas9 methods have been adapted for use in the African... 
Xenopus | CRISPR/Cas9 | Mutagenesis | Issue 132 | TALEN | Genetics | Loss of function | Genome editing | Mutants | SYSTEM | genome editing | PROTEIN | mutants | MULTIDISCIPLINARY SCIENCES | loss of function | mutagenesis | GENOME | NUCLEASES | genetics | MESSENGER-RNA | LAEVIS | GENES | TROPICALIS | EMBRYOS | Gene Targeting - methods | Animals | Germ Cells - transplantation | Xenopus laevis | Cell Transplantation | Mutation | CRISPR-Cas Systems - genetics | CRISPR | Cas9
Journal Article
Genesis, ISSN 1526-954X, 12/2013, Volume 51, Issue 12, pp. 827 - 834
Gene inactivation is an important tool for correlation of phenotypic and genomic data, allowing researchers to infer normal gene function based on the... 
Journal Article
Science, ISSN 0036-8075, 4/2010, Volume 328, Issue 5978, pp. 633 - 636
Journal Article
Developmental Cell, ISSN 1534-5807, 05/2019, Volume 49, Issue 4, pp. 643 - 650.e3
It has recently been reported that a common side effect of translation-blocking morpholino antisense oligonucleotides is the induction of a set of innate... 
Xenopus | translation blocking morpholino | reverse genetics | innate immune response | gene knockdown | zebrafish | tbxt | loss of function | brachyury | SYSTEM | ANTISENSE | GENE-EXPRESSION | DEVELOPMENTAL BIOLOGY | BETA-CATENIN | WNT | GENOME | CELL BIOLOGY
Journal Article
Cold Spring Harbor protocols, ISSN 1940-3402, 04/2019, Volume 2019, Issue 4, p. pdb.prot098335
Transcriptional regulatory elements are typically found in relatively nucleosome-free genomic regions, often referred to as "open chromatin." Deoxyribonuclease... 
Deoxyribonuclease | Chromatin | Transcription factors | Accessibility | Antibodies | Fragments | Genomes | Regulatory sequences | Embryos | Fibers | Polymerase chain reaction | Next-generation sequencing | Deoxyribonuclease I | Interrogation | Nucleosomes | Nuclease | Binding sites | Deoxyribonucleic acid--DNA
Journal Article
Development (Cambridge), ISSN 0950-1991, 12/2014, Volume 141, Issue 23, pp. 4537 - 4547
Journal Article
Cell Reports, ISSN 2211-1247, 06/2019, Volume 27, Issue 10, pp. 2962 - 2977.e5
Elucidation of the sequence of events underlying the dynamic interaction between transcription factors and chromatin states is essential. Maternal... 
endoderm | Vegt | Foxh1 | Otx1 | germ layer specification | enhancer RNAs | histone marks | Xenopus tropicalis | super-enhancers | zygotic genome activation
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2012, Volume 917, pp. 43 - 65
The frog Xenopus laevis has for more than 60 years served as a model system for the study of vertebrate embryogenesis, molecular and cell biology, and... 
Metazome | Genome browser | Xenbase | Gene model | Synteny | Ortholog | User-Computer Interface | Animals | Xenopus - genetics | Databases, Genetic | Search Engine | Genome | Online Systems | Sequence Analysis, DNA | Data Mining - methods
Conference Proceeding
Developmental Cell, ISSN 1534-5807, 03/2017, Volume 40, Issue 6, pp. 595 - 607.e4