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The New England Journal of Medicine, ISSN 0028-4793, 11/2016, Volume 375, Issue 18, pp. 1726 - 1737
In this randomized, controlled trial in Africa and India, combination antiretroviral therapy was more effective than standard therapy in preventing... 
PRETERM DELIVERY | CHILD-MORTALITY | MEDICINE, GENERAL & INTERNAL | TENOFOVIR DISOPROXIL FUMARATE | INFECTED WOMEN | PROGESTERONE LEVELS | ADVERSE BIRTH OUTCOMES | LOPINAVIR/RITONAVIR | LOPINAVIR EXPOSURE | PROTEASE | PREGNANCY | HIV Infections - prevention & control | Infant Mortality | Humans | African Americans | Perinatal Care | Infant | Young Adult | Adult | Female | HIV Infections - transmission | Drug Therapy, Combination | Infant, Newborn | Infant, Low Birth Weight | Anti-Retroviral Agents - therapeutic use | Tenofovir - therapeutic use | Zidovudine - adverse effects | Anti-Retroviral Agents - adverse effects | CD4 Lymphocyte Count | Gestational Age | Pregnancy | Infant, Premature | Zidovudine - therapeutic use | HIV Infections - ethnology | Nevirapine - administration & dosage | Infectious Disease Transmission, Vertical - prevention & control | Pregnancy Outcome | Prevention | Highly active antiretroviral therapy | Complications and side effects | Care and treatment | Nevirapine | Pregnant women | HIV patients | Dosage and administration | Research | HIV (Viruses) | Zidovudine | Health aspects | Emtricitabine | Neonates | Antiretroviral drugs | Breastfeeding & lactation | Ritonavir | Lopinavir | Lamivudine | Infants | Gestation | Antiretroviral therapy | Postpartum | CD4 antigen | Disease prevention | Tenofovir | Cost-benefit analysis | Disease transmission | Maternal & child health | Human immunodeficiency virus--HIV | Birth weight | Drug therapy
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2012, Volume 366, Issue 25, pp. 2380 - 2389
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2010, Volume 363, Issue 16, pp. 1510 - 1520
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2011, Volume 365, Issue 1, pp. 21 - 31
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0148649
Background This study examined the associations of 25-hydroxyvitamin D and specific host genetic variants that affect vitamin D levels or its effects on immune... 
HUMAN GENETIC SUSCEPTIBILITY | D-RECEPTOR POLYMORPHISMS | MULTIDISCIPLINARY SCIENCES | D DEFICIENCY | PULMONARY TUBERCULOSIS | COHORT | AUTOPHAGY | CHILDREN | Follow-Up Studies | Vitamin D Deficiency - complications | Humans | Receptors, Interleukin-1 - genetics | Infant | Male | Tuberculosis, Pulmonary - genetics | Vitamin D Deficiency - mortality | Receptors, Calcitriol - genetics | Phospholipid Transfer Proteins | Tuberculosis, Pulmonary - complications | HIV Infections - immunology | Vitamin D - immunology | Adult | Female | HIV Infections - mortality | Anoctamins | Vitamin D Deficiency - immunology | Plakophilins - immunology | Real-Time Polymerase Chain Reaction | Gene Expression | Genetic Predisposition to Disease | Vitamin D Deficiency - genetics | Membrane Proteins - genetics | Plakophilins - genetics | Receptors, Interleukin-1 - immunology | HIV Infections - genetics | Membrane Proteins - immunology | Vitamin D - blood | Vitamin D-Binding Protein - immunology | Tuberculosis, Pulmonary - immunology | Vitamin D-Binding Protein - genetics | Receptors, Calcitriol - immunology | Tuberculosis, Pulmonary - mortality | HIV Infections - complications | Survival Analysis | Vitamin D - analogs & derivatives | Polymorphism, Single Nucleotide | Cohort Studies | Care and treatment | Tuberculosis | Hydroxylation | Analysis | Development and progression | HIV patients | Infants | Single nucleotide polymorphisms | HIV infection | Chromosomes | Health aspects | Health sciences | Pediatrics | Immunoassay | Disease | Genes | Risk | Innate immunity | Infections | Single-nucleotide polymorphism | Medical diagnosis | Autophagy | Immunity | Vitamin D | Human immunodeficiency virus--HIV | Toll-like receptors | Children | Supplementation | Chronology | Public health | 25-Hydroxyvitamin D | Immune response | Risk groups | Mortality | Health risks | Vitamin deficiency | Chemiluminescence | Breast feeding | Gene expression | Medicine | Genetic variance | Death | Sampling methods | Vitamin D receptors | HIV | Human immunodeficiency virus
Journal Article
PLOS ONE, ISSN 1932-6203, 07/2019, Volume 14, Issue 7, p. e0211155
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 09/2019, Volume 85, Issue 9, pp. 2066 - 2075
Aims Describe the pharmacokinetics (PK) of the antiretroviral drugs abacavir and lamivudine in malnourished paediatric patients and relate to viral load... 
human immunodeficiency virus | abacavir | severe acute malnutrition | children | lamivudine | population pharmacokinetics | NEVIRAPINE | LOPINAVIR | MALNUTRITION | TABLETS | THERAPY | INFANTS | PHARMACOLOGY & PHARMACY | AGE | Highly active antiretroviral therapy | Analysis | Patient outcomes | Body weight | Abacavir | World health | HIV patients | Lamivudine | Children | Index Medicus
Journal Article
PloS one, 2019, Volume 14, Issue 7, p. e0211155
The immune reconstitution inflammatory syndrome (IRIS) in HIV-infected infants and young children is relatively understudied in regions endemic for HIV and TB.... 
Journal Article
South African Journal of Radiology, ISSN 1027-202X, 2016, Volume 20, Issue 1, pp. e1 - e6
Background: Paediatric multidrug-resistant tuberculosis (MDR-TB) necessitates a prolonged duration of treatment with an intensive treatment regimen. The chest... 
Care and treatment | Usage | Tuberculosis | Analysis | X-rays | Research | Children | Health aspects | Prevalence studies (Epidemiology) | Caregivers | Chest | Statistical analysis | Effusion | Pleural effusion | Immune status | Drug resistance | Cavitation | Multidrug resistant organisms | Cavities | Lymphadenopathy | Ionizing radiation | Immunology | Hospitals | X rays | Reviews | Human immunodeficiency virus--HIV | Classification | Radiology | Adults
Journal Article
AIDS Research and Human Retroviruses, ISSN 0889-2229, 01/2018, Volume 34, Issue 1, pp. 46 - 55
This observational study aimed to describe immunopathogenesis and treatment outcomes in children with and without severe acute malnutrition (SAM) and... 
malnutrition | microbial translocation | immune exhaustion | antiretroviral therapy | pediatric HIV | immune activation | MORTALITY | INFECTIOUS DISEASES | GUT MICROBIOTA | IMMUNOLOGY | T-CELL EXHAUSTION | VIRAL REPLICATION | MALNOURISHED CHILDREN | VIROLOGY | AFRICAN CHILDREN | PLASMA-LEVELS | EXPRESSION | HIV-1 | Severity of Illness Index | Acute Disease | Cross-Sectional Studies | Lymphocyte Activation | Humans | Child, Preschool | Infant | Male | Treatment Outcome | CD4 Lymphocyte Count | Biomarkers - blood | Bacterial Translocation | Viral Load | Antiretroviral Therapy, Highly Active | Flow Cytometry | Malnutrition - immunology | HIV Infections - complications | Malnutrition - virology | Female | HIV Infections - drug therapy | Child | Flow cytometry | Therapy | Multiple regression analysis | CD8 antigen | Activation | Lymphocytes T | Recovery | Clinical outcomes | Cell activation | Microorganisms | Intestine | Antiretroviral agents | Lymphocytes | CD38 antigen | Human immunodeficiency virus--HIV | Immunopathogenesis | Children | Malnutrition | Drug therapy | Enzyme-linked immunosorbent assay | Translocation | Antiretroviral drugs | Markers | T cell receptors | Shrinkage | Regression analysis | Antiretroviral therapy | CD4 antigen | Cytometry | Monocytes | Statistical models | Correlation analysis | Exhaustion | Plasma levels | Histocompatibility antigen HLA | Pathogenesis
Journal Article
SA Journal of Radiology, ISSN 2078-6778, 2016, Volume 20, Issue 1, pp. 1 - 6
BACKGROUND: Paediatric multidrug-resistant tuberculosis (MDR-TB) necessitates a prolonged duration of treatment with an intensive treatment regimen. The chest... 
Radiology, Nuclear Medicine & Medical Imaging | Health Care Sciences & Services | Medicine, General & Internal
Journal Article
The Pediatric Infectious Disease Journal, ISSN 0891-3668, 04/2018, Volume 37, Issue 4, pp. 349 - 355
BACKGROUND:In developing countries, malnutrition remains a common clinical syndrome at antiretroviral treatment (ART) initiation. Physiologic changes because... 
severe acute malnutrition | HIV | lopinavir | children | population pharmacokinetics | INFECTIOUS DISEASES | ANTITUBERCULAR TREATMENT | ANTIRETROVIRAL THERAPY | RIFAMPICIN | IMMUNOLOGY | COMBINATION | NEVIRAPINE | FAILURE | MALNUTRITION | TABLETS | PEDIATRICS | LOPINAVIR/RITONAVIR | RITONAVIR | Body Mass Index | Humans | Child, Preschool | Infant | Male |