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Nature Reviews Genetics, ISSN 1471-0056, 11/2012, Volume 13, Issue 11, pp. 770 - 780
Journal Article
Biochemistry, ISSN 0006-2960, 02/2018, Volume 57, Issue 7, pp. 1108 - 1118
PIF1 family helicases are conserved from bacteria to man. With the exception of the well-studied yeast PIF1 helicases (e.g., ScPif1 and ScRrm3), however, very... 
Journal Article
eLife, 04/2014, Volume 2014, Issue 3
Journal Article
Methods in molecular biology (Clifton, N.J.), 2019, Volume 1999, p. 245
Many chemical reactions in the cell are thermodynamically unfavorable. To overcome this barrier, the energy released from the hydrolysis of adenosine... 
Journal Article
Methods in molecular biology (Clifton, N.J.), 2019, Volume 1999, p. 255
Efficient replication and repair of the genome requires a multitude of protein-DNA transactions. These interactions can result in a variety of consequences for... 
Journal Article
Nature, ISSN 0028-0836, 08/2015, Volume 524, Issue 7564, pp. 166 - 167
On page 186 of this issue, Li et al.2 capitalize on advances in cryo-electron microscopy3 to resolve the structure of a eukaryotic helicase, Mcm2-7, to a... 
Physiological aspects | Enzymes | Eukaryotes | DNA replication | Genetic aspects | Analysis | Cell division | Antigens | DNA repair | Deoxyribonucleic acid--DNA
Journal Article
Molecular & Cellular Oncology, ISSN 2372-3556, 09/2014, Volume 1, Issue 3, p. e963429
Genome integrity is achieved and maintained by the sum of all of the processes in the cell that ensure the faithful duplication and repair of DNA, as well as... 
DNA helicase | Pif1 | MCM | RecQ | Rothmund-Thomson syndrome | DnaB | Twinkle | genome integrity | Mcm2-7 | Mcm2–7
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 06/2011, Volume 22, Issue 12, pp. 1955 - 1959
Pif1 family helicases, which are found in nearly all eukaryotes, have important roles in both nuclear and mitochondrial genome maintenance. Recently, the... 
DNA biosynthesis | DNA helicase | Enzymes | Mitochondria | Recombination | Prokaryotes | Replication | Genomes
Journal Article
Microbiology and Molecular Biology Reviews, ISSN 1092-2172, 12/2009, Volume 73, Issue 4, p. 652
  The Mcm2-7 complex serves as the eukaryotic replicative helicase, the molecular motor that both unwinds duplex DNA and powers fork progression during DNA... 
Eukaryotes | Microbiology | Bacteria | Biochemistry | Molecular biology | Deoxyribonucleic acid--DNA
Journal Article
Nucleic Acids Research, ISSN 1362-4962, 01/2010, Volume 38, Issue 18, pp. 6078 - 6088
The Mcm2-7 complex is the eukaryotic replicative helicase, a toroidal AAA+ molecular motor that uses adenosine triphosphate (ATP) binding and hydrolysis to... 
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 05/2010, Volume 38, Issue 18, pp. 6078 - 6088
The Mcm2-7 complex is the eukaryotic replicative helicase, a toroidal AAA(+) molecular motor that uses adenosine triphosphate (ATP) binding and hydrolysis to... 
FORMS | COMPLEX | REPRESSOR-OPERATOR INTERACTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROLYSIS | MECHANISMS | EUKARYOTIC DNA | PROTEINS | HELICASE | Minichromosome Maintenance Complex Component 6 | Minichromosome Maintenance Complex Component 7 | Minichromosome Maintenance Complex Component 3 | Protein Subunits - metabolism | Cell Cycle Proteins - chemistry | DNA-Binding Proteins - metabolism | Cell Cycle Proteins - genetics | Nuclear Proteins - genetics | DNA Helicases - genetics | Protein Subunits - genetics | DNA Helicases - chemistry | Catalytic Domain | Chromosomal Proteins, Non-Histone - metabolism | DNA, Single-Stranded - metabolism | Cell Cycle Proteins - metabolism | Adenosine Triphosphatases - metabolism | Nuclear Proteins - metabolism | DNA - metabolism | Saccharomyces cerevisiae Proteins - genetics | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | DNA, Circular - metabolism | DNA-Binding Proteins - chemistry | Chromosomal Proteins, Non-Histone - genetics | DNA Helicases - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | Protein Subunits - chemistry | Kinetics | Mutation | Chromosomal Proteins, Non-Histone - chemistry | Saccharomyces cerevisiae Proteins - chemistry | Genome Integrity, Repair and
Journal Article
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