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PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e50852
Respiratory Syncytial Virus (RSV) is an important viral agent causing severe respiratory tract disease in infants and children as well as in the elderly and... 
VACCINE DEVELOPMENT | RSV F | IMMUNIZATION | STRUCTURAL BASIS | MULTIDISCIPLINARY SCIENCES | DISEASE | ANTIBODY | INFECTION | MOTAVIZUMAB | NEUTRALIZATION | F-GLYCOPROTEIN | Surface Plasmon Resonance | Nanoparticles - chemistry | Humans | Respiratory Syncytial Viruses - immunology | Male | Chromatography, High Pressure Liquid | Respiratory Syncytial Virus Infections - immunology | Viral Fusion Proteins - immunology | Lung - virology | Palivizumab | Sf9 Cells | Viral Fusion Proteins - chemistry | Light | Respiratory Syncytial Virus Infections - prevention & control | Mutant Proteins - immunology | Scattering, Radiation | Disease Models, Animal | Protein Structure, Tertiary | Amino Acid Sequence | Lung - pathology | Sigmodontinae - immunology | Viral Fusion Proteins - isolation & purification | Nanoparticles - ultrastructure | Immunity - immunology | Glycoproteins - immunology | Animals | Mutant Proteins - chemistry | Sigmodontinae - virology | Antibodies, Viral - immunology | Antibodies, Monoclonal, Humanized - immunology | Nanoparticles | Oligomers | Immunoglobulin G | Monoclonal antibodies | Children | Vaccines | Biopolymers | Formaldehyde | Diseases | Antigenic determinants | Elderly people | Membranes | Disease | Viruses | Amino acids | Infants | Infections | Baculovirus | Cotton | Immunity | Proteins | Respiratory tract | Medical laboratories | Respiratory tract diseases | Recombinant | Antigens | Immunization | Immunoglobulins | Polypeptides | Cloning | Glycoprotein | Rats | Glycoproteins | Cell membranes | Respiratory syncytial virus | Immunogenicity | Lungs | Insects | Insect cells | Neutralizing | Mutation | Laboratory animals | Elderly | Geriatrics | Cell membranes (biology)
Journal Article
Vaccine, ISSN 0264-410X, 2012, Volume 31, Issue 3, pp. 524 - 532
Highlights ► This Phase 1 trial evaluated the safety and immunogenicity of an RSV (F) nanoparticle vaccine. ► The vaccine was well-tolerated and no related... 
Allergy and Immunology | Respiratory syncytial virus (RSV) | Palivizumab | Fusion protein (F protein) | Competitive ELISA | SF9 insect cell | Microneutralization | Aluminum phosphate | Anti-F IgG | Nanoparticle vaccine | UNITED-STATES | MEDICINE, RESEARCH & EXPERIMENTAL | NEUTRALIZING ANTIBODIES | IMMUNE GLOBULIN | COTTON RATS | INFLUENZA | RISK | IMMUNOLOGY | F-GLYCOPROTEIN | INFANTS | INFECTION | YOUNG-CHILDREN | Recombinant Fusion Proteins - immunology | Single-Blind Method | Biotechnology | Respiratory Syncytial Virus Vaccines - immunology | Adjuvants, Immunologic - administration & dosage | Aluminum Compounds - adverse effects | Phosphates - administration & dosage | Recombinant Fusion Proteins - adverse effects | Humans | Middle Aged | Male | Nanoparticles - adverse effects | Vaccines, Synthetic - immunology | Antibodies, Viral - blood | Adjuvants, Immunologic - adverse effects | Young Adult | Respiratory Syncytial Virus Vaccines - adverse effects | Sf9 Cells | Technology, Pharmaceutical | Vaccines, Virosome - immunology | Vaccines, Synthetic - adverse effects | Placebos - adverse effects | Adult | Female | Placebos - administration & dosage | Recombinant Fusion Proteins - administration & dosage | Vaccines, Virosome - administration & dosage | Vaccines, Synthetic - genetics | Vaccines, Virosome - genetics | Animals | Aluminum Compounds - administration & dosage | Phosphates - adverse effects | Vaccines, Virosome - adverse effects | Respiratory Syncytial Virus Vaccines - administration & dosage | Adolescent | Recombinant Fusion Proteins - genetics | Nanoparticles - administration & dosage | Vaccines, Synthetic - administration & dosage | Respiratory Syncytial Virus Vaccines - genetics | Antibodies, Neutralizing - blood | Virus diseases | Phosphates | Vaccines | Immunoglobulin G | Enzyme-linked immunosorbent assay | Proteins | Nanoparticles | Infections | Index Medicus
Journal Article
Vaccine, ISSN 0264-410X, 01/2013, Volume 31, Issue 3, pp. 524 - 532
Objective: We performed a Phase 1 randomized, observer-blinded, placebo-controlled trial to evaluate the safety and immunogenicity of a recombinant respiratory... 
Journal Article
Rejuvenation Research, ISSN 1549-1684, 12/2007, Volume 10, Issue 4, pp. 561 - 570
Journal Article
Journal Article
Mitochondrion, ISSN 1567-7249, 2007, Volume 7, Issue 6, pp. 406 - 406
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2005, Volume 11, Issue S1, pp. S426 - S426
Journal Article
Rejuvenation research, ISSN 1549-1684, 12/2007, Volume 10, Issue 4, p. 561
Mitochondrial DNA mutations are the direct cause of several physiological disorders and are also associated with the aging process. The modest progress made... 
Animals | DNA, Mitochondrial - genetics | Humans | Cells, Cultured | Oxygen Consumption | Polymerase Chain Reaction | Transplantation, Heterologous | Mice | Mutation | Mitochondria - physiology | Mitochondria - transplantation | Microscopy, Fluorescence
Journal Article
Journal of Liposome Research, ISSN 0898-2104, 2005, Volume 15, Issue 1-2, pp. 49 - 58
Mitochondrial dysfunction contributes to a large variety of human disorders, ranging from neurodegenerative and neuromuscular diseases, obesity, and diabetes... 
Mitochondria | Liposomes | Subcellular drug targeting | Mitochondrial drug delivery | Triphenylphosphonium salts | Delocalized cations (DLCs)
Journal Article
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