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Nature chemical biology, ISSN 1552-4469, 2019, Volume 15, Issue 7, pp. 672 - 680
Journal Article
The Journal of cell biology, ISSN 1540-8140, 2008, Volume 180, Issue 4, pp. 803 - 812
Journal Article
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 12/2014, Volume 6, Issue 12, pp. 1525 - 1541
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2003, Volume 278, Issue 52, pp. 52689 - 52699
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Molecular cancer therapeutics, ISSN 1535-7163, 10/2016, Volume 15, Issue 10, pp. 2388 - 2398
Journal Article
The EMBO Journal, ISSN 0261-4189, 10/2000, Volume 19, Issue 19, pp. 5092 - 5104
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Journal Article
Nature chemical biology, ISSN 1552-4469, 2019, Volume 15, Issue 8, pp. 822 - 829
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Journal of medicinal chemistry, ISSN 0022-2623, 11/2016, Volume 59, Issue 22, pp. 10147 - 10162
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Structure (London), ISSN 0969-2126, 04/2019, Volume 27, Issue 4, pp. 590 - 605.e5
The multi-domain deubiquitinase USP15 regulates diverse eukaryotic processes and has been implicated in numerous diseases. We developed ubiquitin variants... 
USP15 | TGF-β pathway | ubiquitin-like | USP4 | phage display | UbV | catalytic domain | ubiquitin | DUSP | deubiquitinase | SPECIFICITY | RECOGNITION | PHOSPHORYLATION | CENTROSOME | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISCOVERY | DEUBIQUITINATING ENZYMES | CELL BIOLOGY | DEUBIQUITYLATING ENZYMES | BIOPHYSICS | CELL-CYCLE | E3 LIGASES | MODULATION | Ubiquitin-Specific Proteases - genetics | Transcription Factors - chemistry | Humans | Protein Multimerization | Transforming Growth Factor beta1 - metabolism | Ubiquitin - metabolism | Substrate Specificity | Crystallography, X-Ray | Transforming Growth Factor beta1 - chemistry | Ubiquitin-Specific Proteases - chemistry | Ubiquitination | Cloning, Molecular | Escherichia coli - metabolism | HEK293 Cells | Protein Interaction Domains and Motifs | Ubiquitin-Specific Proteases - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Protein Conformation, alpha-Helical | Tripartite Motif Proteins - chemistry | Catalytic Domain | Gene Expression | Genetic Vectors - chemistry | Ubiquitin-Specific Proteases - antagonists & inhibitors | Ubiquitin - chemistry | Ubiquitin-Protein Ligases - metabolism | Genetic Vectors - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Tripartite Motif Proteins - genetics | Recombinant Proteins - genetics | Transforming Growth Factor beta1 - genetics | Ubiquitin - genetics | Transcription Factors - genetics | Ubiquitin-Protein Ligases - chemistry | Sequence Homology, Amino Acid | Transcription Factors - metabolism | Sequence Alignment | Protein Conformation, beta-Strand | Escherichia coli - genetics | Protein Binding | Tripartite Motif Proteins - metabolism | Ubiquitin-Protein Ligases - genetics | Ubiquitin | Bone morphogenetic proteins | Transforming growth factors | Analysis
Journal Article