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Biological Psychiatry, ISSN 0006-3223, 10/2019
Journal Article
Biological Psychiatry, ISSN 0006-3223, 04/2012, Volume 71, Issue 8, pp. 714 - 724
Background: Cannabinoid CB receptors (CB Rs) mediate the effects of -tetrahydrocannabinol (THC), the psychoactive component in marijuana. Repeated THC... 
GPCR | cannabinoid receptors | tolerance | Beta-arrestin | statistical parametric mapping
Journal Article
Science Signaling, ISSN 1945-0877, 08/2018, Volume 11, Issue 542
Journal Article
Drug and Alcohol Dependence, ISSN 0376-8716, 10/2018, Volume 191, p. 195
Previous reports assessing morphine effects in two bottle choice (TBC) paradigms often use taste adulterants such as sweeteners (e.g., saccharin) and/or... 
Consumption | Brain | Drug abuse | Narcotics | Abuse | Fentanyl | Morphine | Pharmacology | Conversion | Sweeteners | Quinine | Clinical outcomes | Saccharin | Liability | Animals | Adulterants | Rodents | Opioids | Dependence | Mice | Taste | Models | Laboratory animals
Journal Article
Pharmacological Reviews, ISSN 0031-6997, 12/2011, Volume 63, Issue 4, pp. 1001 - 1019
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 01/2016, Volume 26, Issue 2, pp. 241 - 250
Journal Article
Neuropharmacology, ISSN 0028-3908, 12/2015, Volume 99
The kappa opioid receptor (KOR) is involved in mediating pruritus; agonists targeting this receptor have been used to treat chronic intractable itch.... 
Phosphates | Chloroquine | Mice | Pruritus | G proteins | Investigations | Membrane proteins
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 07/2014, Volume 39, Issue 8, p. 1902
  The G protein-coupled serotonin 2A receptor (5-HT2AR) is a prominent target for atypical antipsychotic drugs, such as clozapine. Although clozapine is known... 
Journal Article
Methods in molecular biology (Clifton, N.J.), 2019, Volume 1957, p. 235
G protein-coupled receptors (GPCRs) can interact with both G proteins and β-arrestin proteins to propagate different signaling outputs. In some contexts,... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2011, Volume 286, Issue 36, pp. 31731 - 31741
Morphine and other opiates mediate their effects through activation of the μ-opioid receptor (MOR), and regulation of the MOR has been shown to critically... 
Receptor Regulation | G Protein-coupled Receptors (GPCR) | Ubiquitination | Phosphorylation | Signal Transduction | Tolerance | Morphine | Receptor Desensitization | Receptor Endocytosis | Arrestin | Receptor Resensitization
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2010, Volume 30, Issue 40, pp. 13513 - 13524
Hallucinogens mediate many of their psychoactive effects by activating serotonin 2A receptors (5-HT2AR). Although serotonin is the cognate endogenous... 
HEAD-TWITCH RESPONSE | 7-TRANSMEMBRANE RECEPTORS | 5-HYDROXYTRYPTAMINE (5-HT)(2A) | 5-HT2C RECEPTORS | BETA-ARRESTINS | BEHAVIOR | FUNCTIONAL SELECTIVITY | PSYCHOTIC DISORDERS | NEUROSCIENCES | PREFRONTAL CORTEX | AGONIST
Journal Article
Biological Psychiatry, ISSN 0006-3223, 04/2012, Volume 71, Issue 8, p. 714
Cannabinoid CB.sub.1 receptors (CB.sub.1Rs) mediate the effects of a[micro].sup.9-tetrahydrocannabinol (THC), the psychoactive component in marijuana. Repeated... 
Journal Article