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Food and Chemical Toxicology, ISSN 0278-6915, 02/2018, Volume 112, pp. 242 - 250
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 01/2018, Volume 339, pp. 10 - 23
This study aims to evaluate the evidence for the existence of non-monotonic dose-responses (NMDRs) of substances in the area of food safety. This review was... 
Dose-response analysis | NMDR | Non-monotonic dose-response relationship | Systematic Review | ENDOCRINE-DISRUPTING CHEMICALS | RATS | CAFFEINE | CONTINUOUS END-POINTS | ADOLESCENT | HORMESIS | METHYLMERCURY | PHARMACOLOGY & PHARMACY | MICE | TOXICOLOGY | RECEPTORS | INDUCED LOCOMOTOR-ACTIVITY | Analysis | Safety and security measures | Food | Index Medicus
Journal Article
Regulatory Toxicology and Pharmacology, ISSN 0273-2300, 02/2013, Volume 65, Issue 1, pp. 79 - 86
► Comparison of ECETOC TRA dermal model with physics-based exposure model. ► ECETOC TRA did not provide conservative estimates in the scenarios considered. ►... 
REACH | Emission | Exposure | ECETOC TRA | Consumer | Modeling | MEDICINE, LEGAL | EMISSIONS | COEFFICIENTS | PHARMACOLOGY & PHARMACY | DIFFUSION | TOXICOLOGY | PARTITION | BUILDING-MATERIALS | VOLATILE ORGANIC-COMPOUNDS | Environmental Exposure - adverse effects | Models, Theoretical | Risk Assessment - methods | Skin - metabolism | Europe | Humans | Consumer Product Safety - standards | Diffusion | Index Medicus
Journal Article
Human and Ecological Risk Assessment: An International Journal, ISSN 1080-7039, 04/2015, Volume 21, Issue 3, pp. 763 - 780
Health impact assessments (HIA) have become an important tool for applying evidence-based policy. Recently, the concept of HIA has been introduced in the field... 
disability adjusted life year (DALY) | health impact assessment (HIA) | benchmark dose | dose-response relationship | animal testing | subclinical effects | dose–response relationship | RISK-BENEFIT ANALYSIS | PESTICIDES | ENVIRONMENTAL SCIENCES | DALYS | EDS | DISEASE | DISABILITY | FISH | FRAMEWORK | ADJUSTED LIFE-YEARS | BURDEN
Journal Article
Archives of Toxicology, ISSN 0340-5761, 3/2013, Volume 87, Issue 3, pp. 505 - 515
The traditional 2-year cancer bioassay needs replacement by more cost-effective and predictive tests. The use of toxicogenomics in an in vitro system may... 
Physiologically based kinetic modeling | Benzo[ a ]pyrene | Biomedicine | Environmental Health | Occupational Medicine/Industrial Medicine | Pharmacology/Toxicology | Toxicogenomics | Carcinogenesis | Biomedicine general | Xpa −/− p53 | Xpa | Benzo[a]pyrene | p53 | Xpa(-/-)p53(+/-) | CDT1 | RAT | CARCINOGENS | COLLAGEN STRUCTURE | DNA-REPLICATION | PREDICTION | MESSENGER-RNA | PHARMACOKINETIC MODELS | CELL-CYCLE | MICE | TOXICOLOGY | Transcription, Genetic - drug effects | Liver - pathology | Apoptosis - drug effects | DNA Replication - drug effects | Liver Neoplasms - chemically induced | Apoptosis - genetics | Hepatocytes - pathology | Male | Cell Transformation, Neoplastic - chemically induced | Gene Expression Profiling | Hepatocytes - metabolism | DNA Adducts - metabolism | Tumor Suppressor Protein p53 - genetics | Carcinogens - toxicity | Dose-Response Relationship, Drug | Liver - drug effects | Cell Transformation, Neoplastic - genetics | Computer Simulation | Liver Neoplasms - pathology | Carcinogens - pharmacokinetics | Gene Expression Regulation, Neoplastic - drug effects | Hepatocytes - drug effects | Benzo(a)pyrene - toxicity | Liver Neoplasms - genetics | Risk Assessment | Carcinogenicity Tests - methods | Liver - metabolism | Mice, Inbred C57BL | Xeroderma Pigmentosum Group A Protein - genetics | Cells, Cultured | Cell Transformation, Neoplastic - metabolism | Benzo(a)pyrene - pharmacokinetics | Mice, Knockout | Animals | High-Throughput Screening Assays | Models, Biological | Liver Neoplasms - metabolism | Mice | Primary Cell Culture | Cell Transformation, Neoplastic - pathology | DNA replication | Benzopyrene | Genes | Genomics | Physiological aspects | Tumor proteins | Xenobiotics | Gene expression | Public health | Carcinogens | Toxicity | Pathogenesis | Cancer | Index Medicus
Journal Article
Nanotoxicology, ISSN 1743-5390, 2011, Volume 5, Issue 3, pp. 393 - 405
This study uniquely describes all steps of the risk assessment process for the use of one specific nanomaterial (nanosilica) in food products. The aim was to... 
BU Microbiologische & Chemische Voedselanalyse | Rikilt B&T Toxicologie en Effectanalyse | RIKILT - Analyse & Ontwikkeling | RIKILT - R&C Contaminanten | BU Microbiological & Chemical Food Analysis
Journal Article
EFSA Supporting Publications, ISSN 2397-8325, 05/2016, Volume 13, Issue 5, p. n/a
Journal Article
International Journal of Environment and Health, ISSN 1743-4955, 05/2012, Volume 6, Issue 1, pp. 37 - 47
The age at which a disability starts is important information when performing a quantitative health impact assessment of any particular chemical substance.... 
Dose-response | Health impact assessment | Time-response | Risk-benefit assessment
Journal Article
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