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by Gieger, Christian and Radhakrishnan, Aparna and Cvejic, Ana and Tang, Weihong and Porcu, Eleonora and Pistis, Giorgio and Serbanovic-Canic, Jovana and Elling, Ulrich and Goodall, Alison H and Labrune, Yann and Lopez, Lorna M and Mägi, Reedik and Meacham, Stuart and Okada, Yukinori and Pirastu, Nicola and Sorice, Rossella and Teumer, Alexander and Voss, Katrin and Zhang, Weihua and Ramirez-Solis, Ramiro and Bis, Joshua C and Ellinghaus, David and Gögele, Martin and Hottenga, Jouke-Jan and Langenberg, Claudia and Kovacs, Peter and O'Reilly, Paul F and Shin, So-Youn and Esko, Tõnu and Hartiala, Jaana and Kanoni, Stavroula and Murgia, Federico and Parsa, Afshin and Stephens, Jonathan and van der Harst, Pim and van der Schoot, C. Ellen and Allayee, Hooman and Attwood, Antony and Balkau, Beverley and Bastardot, François and Basu, Saonli and Baumeister, Sebastian E and Biino, Ginevra and Bomba, Lorenzo and Bonnefond, Amélie and Cambien, François and Chambers, John C and Cucca, Francesco and D'Adamo, Pio and Davies, Gail and de Boer, Rudolf A and de Geus, Eco J. C and Döring, Angela and Elliott, Paul and Erdmann, Jeanette and Evans, David M and Falchi, Mario and Feng, Wei and Folsom, Aaron R and Frazer, Ian H and Gibson, Quince D and Glazer, Nicole L and Hammond, Chris and Hartikainen, Anna-Liisa and Heckbert, Susan R and Hengstenberg, Christian and Hersch, Micha and Illig, Thomas and Loos, Ruth J. F and Jolley, Jennifer and Khaw, Kay Tee and Kühnel, Brigitte and Kyrtsonis, Marie-Christine and Lagou, Vasiliki and Lloyd-Jones, Heather and Lumley, Thomas and Mangino, Massimo and Maschio, Anea and Mateo Leach, Irene and McKnight, Barbara and Memari, Yasin and Mitchell, Braxton D and Montgomery, Grant W and Nakamura, Yusuke and Nauck, Matthias and Navis, Gerjan and Nöthlings, Ute and Nolte, Ilja M and Porteous, David J and Pouta, Anneli and Pramstaller, Peter P and Pullat, Janne and Ring, Susan M and Rotter, Jerome I and Ruggiero, Daniela and Ruokonen, Aimo and Sala, Cinzia and Samani, Nilesh J and Sambrook, Jennifer and Schlessinger, David and ...
Nature, ISSN 0028-0836, 2011, Volume 480, Issue 7376, pp. 201 - 208
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 04/2018, Volume 64, pp. 33 - 43
Modulation of insulin-dependent signaling is emerging as a valuable therapeutic tool to target neurodegeneration. In the brain, the activation of insulin... 
Cognitive enhancement | GLP-1 | Type 2 diabetes mellitus | GLP-1 receptor | Long-term potentiation | NERVOUS-SYSTEM | LONG-TERM-MEMORY | ALZHEIMERS-DISEASE | PROTEIN-KINASE | BRAIN INSULIN-RESISTANCE | SYNAPTIC PLASTICITY | NEUROSCIENCES | GERIATRICS & GERONTOLOGY | GLUCAGON-LIKE PEPTIDE-1 | DENDRITIC SPINE | GENE-EXPRESSION | PARKINSONS-DISEASE
Journal Article
JOURNAL OF ALZHEIMERS DISEASE, ISSN 1387-2877, 2019, Volume 70, Issue 3, pp. 793 - 810
Alzheimer's disease (AD) is a multifactorial condition in which, along with amyloid-beta (A beta) and tau-related pathology, the synergistic activity of... 
T2DM | OXIDATIVE STRESS | insulin | BDNF | NEUROTROPHIC FACTOR | BRAIN INSULIN-RESISTANCE | MOUSE | RECEPTOR | TRANSGENIC MODEL | SYNAPTIC PLASTICITY | NEUROSCIENCES | GLUCOSE-HOMEOSTASIS | GLUCAGON-LIKE PEPTIDE-1 | neurotrophic factors | Aging | A-BETA | dementia | diabetes | exendin-4 | insulin resistance
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2014, Volume 81, pp. 214 - 224
Journal Article
AGING-US, ISSN 1945-4589, 08/2019, Volume 11, Issue 16, pp. 6336 - 6357
Although aging is considered to be an unavoidable event, recent experimental evidence suggests that the process can be counteracted. Intracellular calcium... 
ACTIVATION | calcium | mitochondria | fluorescence imaging | ALZHEIMERS-DISEASE | INVOLVEMENT | CALCIUM HYPOTHESIS | BETA | P53 | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | excitability | CORTICAL-NEURONS | SERINE PALMITOYLTRANSFERASE | oxidative stress | BRAIN
Journal Article
Neurobiology of aging, 12/2017, Volume 64, p. 33
Modulation of insulin-dependent signaling is emerging as a valuable therapeutic tool to target neurodegeneration. In the brain, the activation of insulin... 
Journal Article
by Abraham, Jella-Andrea and Golubnitschaja, Olga and Akhmetov, Ildar and Andrews, Russell J and Quintana, Leonidas and Baban, Babak and Liu, Jun Yao and Qin, Xu and Wang, Tailing and Mozaffari, Mahmood S and Bati, Viktoriia V and Meleshko, Tamara V and Levchuk, Olga B and Boyko, Nadiya V and Bauer, Joanna and Boerner, Ewa and Podbielska, Halina and Bomba, Alojz and Petrov, Viktor O and Drobnych, Volodymyr G and Bubnov, Rostyslav V and Bykova, Oksana M and Brunner-La Rocca, Hans-Peter and Fleischhacker, Lutz and Heemskerk, Frank and Helms, Thomas and Jaarsma, Tiny and Kinkorová, Judita and Ramaekers, Jan and Ruff, Peter and Schnur, Ivana and Vanoli, Emilio and Verdu, Jose and Grabovetskyi, Sergiy A and Mykhalchenko, Olena M and Tymoshok, Natalia O and Shcherbakov, Oleksandr B and Semeniv, Igor P and Spivak, Mykola Y and Ostapenko, Tetyana V and Kobyliak, Nazarii M and Zholobak, Nadiya M and Spivak, Mykola Ya and Cauchi, John Paul and Cherepakhin, Dmitrii and Bakay, Marina and Borovikov, Artem and Suchkov, Sergey and Cieślik, Barbara and Migasiewicz, Agnieszka and Podbielska, Maria-Luiza and Pelleter, Markus and Giemza, Agnieszka and Cirak, Sebahattin and Del Re, Marzia and Bordi, Paola and Citi, Valentina and Palombi, Marta and Pinto, Carmine and Tiseo, Marcello and Danesi, Romano and Einhorn, Lukas and Fazekas, Judit and Muhr, Martina and Schoos, Alexandra and Panakova, Lucia and Herrmann, Ina and Manzano-Szalai, Krisztina and Oida, Kumiko and Fiebiger, Edda and Singer, Josef and Jensen-Jarolim, Erika and Elnar, Arpiné A and Ouamara, Nadia and Boyko, Nadiya and Coumoul, Xavier and Antignac, Jean-Philippe and Le Bizec, Bruno and Eppe, Gauthier and Renaut, Jenny and Bonn, Torsten and Guignard, Cédric and Ferrante, Margherita and Chiusano, Maria Liusa and Cuzzocrea, Salvatore and O’Keeffe, Gerard and Cryan, John and Bisson, Michelle and Barakat, Amina and Hmamouchi, Ihsane and Zawia, Nasser and Kanthasamy, Anumantha and Kisby, Glen E and Alves, Rui and Pérez, Oscar Villacañas and Burgard, Kim and Spencer, Peter and Bomba, Norbert and Haranta, Martin and Zaitseva, Nina and ... and on behalf of MOSAIC consortium and on behalf of ZENITH consortium and EFLM
EPMA Journal, ISSN 1878-5077, 05/2016, Volume 7, Issue S1, p. 1
A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma... 
Hypertension | Stroke | Laboratories | Diabetic neuropathy | Breast cancer | Metastasis | Dentistry | Patients | Cancer therapies | Fatty acids | Quality of life | Consortia | Disease prevention | Liver cancer | Ultrasonic imaging | Sleep | Education reform | Precision medicine | Womens health | Ulcers | Biomarkers | Diabetes | Deoxyribonucleic acid--DNA
Journal Article
by Gieger, Christian and Radhakrishnan, Aparna and Cvejic, Ana and Tang, Weihong and Porcu, Eleonora and Pistis, Giorgio and Serbanovic-Canic, Jovana and Elling, Ulrich and Goodall, Alison H and Labrune, Yann and Lopez, Lorna M and Maegi, Reedik and Meacham, Stuart and Okada, Yukinori and Pirastu, Nicola and Sorice, Rossella and Teumer, Alexander and Voss, Katrin and Zhang, Weihua and Ramirez-Solis, Ramiro and Bis, Joshua C and Ellinghaus, David and Goegele, Martin and Hottenga, Jouke-Jan and Langenberg, Claudia and Kovacs, Peter and O'Reilly, Paul F and Shin, So-Youn and Esko, Toenu and Hartiala, Jaana and Kanoni, Stavroula and Murgia, Federico and Parsa, Afshin and Stephens, Jonathan and van der Harst, Pim and van der Schoot, C. Ellen and Allayee, Hooman and Attwood, Antony and Balkau, Beverley and Bastardot, Francois and Basu, Saonli and Baumeister, Sebastian E and Biino, Ginevra and Bomba, Lorenzo and Bonnefond, Amelie and Cambien, Francois and Chambers, John C and Cucca, Francesco and D'Adamo, Pio and Davies, Gail and de Boer, Rudolf A and de Geus, Eco J. C and Doering, Angela and Elliott, Paul and Erdmann, Jeanette and Evans, David M and Falchi, Mario and Feng, Wei and Folsom, Aaron R and Frazer, Ian H and Gibson, Quince D and Glazer, Nicole L and Hammond, Chris and Hartikainen, Anna-Liisa and Heckbert, Susan R and Hengstenberg, Christian and Hersch, Micha and Illig, Thomas and Loos, Ruth J. F and Jolley, Jennifer and Khaw, Kay Tee and Kuehnel, Brigitte and Kyrtsonis, Marie-Christine and Lagou, Vasiliki and Lloyd-Jones, Heather and Lumley, Thomas and Mangino, Massimo and Maschio, Anea and Mateo Leach, Irene and McKnight, Barbara and Memari, Yasin and Mitchell, Braxton D and Montgomery, Grant W and Nakamura, Yusuke and Nauck, Matthias and Navis, Gerjan and Noethlings, Ute and Nolte, Ilja M and Porteous, David J and Pouta, Anneli and Pramstaller, Peter P and Pullat, Janne and Ring, Susan M and Rotter, Jerome I and Ruggiero, Daniela and Ruokonen, Aimo and Sala, Cinzia and Samani, Nilesh J and Sambrook, Jennifer and Schlessinger, David and ...
Nature, ISSN 0028-0836, 12/2011, Volume 480, Issue 7376, pp. 201 - 208
Platelets are the second most abundant cell type in blood and are essential for maintaining haemostasis. Their count and volume are tightly controlled within... 
POPULATION | HEMATOPOIESIS | LOCI | UMCG Approved | DROSOPHILA | GENOME-WIDE ASSOCIATION | BLOOD
Journal Article
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