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Gastroenterology, ISSN 0016-5085, 10/2017, Volume 153, Issue 4, pp. 1107 - 1119.e10
Ligand binding to inhibitory receptors on immune cells, such as programmed cell death 1 (PD-1) and cytotoxic T-lymphocyte associated protein 4 (CTLA4),... 
GPC3 | MAGEC2 | Immunotherapy | Galectin 9 | SAFETY | CANCER | RESPONSES | ADVANCED MELANOMA | PEPTIDE-MHC | NIVOLUMAB | GASTROENTEROLOGY & HEPATOLOGY | UP-REGULATION | PD-1 | TETRAMERS | EXHAUSTION | Tumor Escape - drug effects | Antigens, CD - immunology | Up-Regulation | Immunotherapy - methods | Coculture Techniques | Humans | Hepatitis A Virus Cellular Receptor 2 - metabolism | Tumor Microenvironment | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antigens, CD - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Hepatitis A Virus Cellular Receptor 2 - antagonists & inhibitors | Carcinoma, Hepatocellular - drug therapy | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Liver Neoplasms - pathology | Lymphocytes, Tumor-Infiltrating - metabolism | Antineoplastic Agents - pharmacology | Carcinoma, Hepatocellular - immunology | Hepatitis A Virus Cellular Receptor 2 - immunology | Cytokines - metabolism | Antibodies, Monoclonal - pharmacology | Cells, Cultured | Liver Neoplasms - drug therapy | CTLA-4 Antigen - metabolism | Programmed Cell Death 1 Receptor - metabolism | Antibodies, Neutralizing - pharmacology | Liver Neoplasms - immunology | Lymphocytes, Tumor-Infiltrating - drug effects | CTLA-4 Antigen - immunology | Signal Transduction - drug effects | Lymphocyte Activation - drug effects | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | T-Lymphocytes - immunology | Cell Proliferation - drug effects | Programmed Cell Death 1 Receptor - immunology | CTLA-4 Antigen - antagonists & inhibitors | Carcinoma, Hepatocellular - metabolism | Lymphocytes, Tumor-Infiltrating - immunology | Viral antibodies | Cell death | Analysis | Melanoma | Antibodies | T cells | Lung cancer, Non-small cell | Cancer | Liver cancer | Dendritic cells | Tumor antigens | Lung cancer | Immunity
Journal Article
International Journal of Cancer, ISSN 0020-7136, 08/2017, Volume 141, Issue 3, pp. 572 - 582
Understanding the mechanisms of immune resistance in pancreatic and ampullary cancers is crucial for the development of suitable biomarkers and effective... 
HLA‐G | galectin‐9 | HVEM | tumor infiltrating lymphocytes | PD‐L1 | PD-L1 | HLA-G | galectin-9 | ANTIBODY | ONCOLOGY | IMMUNOTHERAPY | PATHWAY | POOR-PROGNOSIS | LEUKOCYTE ANTIGEN-G | SURFACE | T-CELLS | Common Bile Duct Neoplasms - mortality | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Pancreatic Neoplasms - metabolism | Prognosis | Humans | Middle Aged | Male | Galanin - metabolism | Ampulla of Vater - metabolism | Aged, 80 and over | Biomarkers, Tumor - metabolism | Adult | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Pancreatic Neoplasms - mortality | Retrospective Studies | Common Bile Duct Neoplasms - immunology | Ampulla of Vater - immunology | B7-H1 Antigen - metabolism | Receptors, Tumor Necrosis Factor, Member 14 - metabolism | Lymphocytes, Tumor-Infiltrating - pathology | Common Bile Duct Neoplasms - metabolism | Pancreatic Neoplasms - immunology | Aged | HLA-G Antigens - metabolism | Lymphocytes, Tumor-Infiltrating - immunology | Immunohistochemistry | Histocompatibility antigens | Lymphocytes | Analysis | Immunotherapy | Pancreatic cancer | HLA histocompatibility antigens | Panels | CD8 antigen | Clinical trials | Complexity | Galectin-9 | Immunology | Foxp3 protein | Inhibition | Pancreas | Immune system | Cell survival | Adjustment | Tools | Survival | Patients | Cell number | PD-L1 protein | Pancreas transplantation | Biomarkers | Histocompatibility antigen HLA | Cancer | Tumors
Journal Article
Science Signaling, ISSN 1945-0877, 04/2017, Volume 10, Issue 476, p. eaah4248
Interferon (IFN)-stimulated genes (ISGs) are antiviral effectors that are induced by IFNs through the formation of a tripartite transcription factor ISGF3,... 
IMMUNE-RESPONSE | IFN-BETA | CELLS | MEDIATED DISEASE | SPECIFICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEPATITIS-E VIRUS | DNA-DAMAGE | RESISTANCE | STAT1 KNOCKOUT MICE | LYMPHOCYTIC CHORIOMENINGITIS VIRUS | CELL BIOLOGY | Embryo, Mammalian - drug effects | Intestines - drug effects | Liver - virology | Interferon-alpha - pharmacology | Hepatitis E virus - drug effects | Hepatitis C - metabolism | Humans | Hepatitis E - virology | Hepatitis E - metabolism | Intestines - metabolism | Embryo, Mammalian - metabolism | Hepatitis E - prevention & control | STAT1 Transcription Factor - metabolism | Interferon-Stimulated Gene Factor 3 - genetics | Liver - drug effects | Interferon-Stimulated Gene Factor 3 - metabolism | Intestines - virology | Embryo, Mammalian - virology | Phosphorylation - drug effects | Hepatitis C - prevention & control | Fibroblasts - metabolism | Fibroblasts - virology | Hepacivirus - drug effects | Virus Replication - drug effects | Antiviral Agents - pharmacology | Liver - metabolism | Cells, Cultured | Interferon-Stimulated Gene Factor 3, gamma Subunit - genetics | STAT1 Transcription Factor - genetics | Interferon-Stimulated Gene Factor 3, gamma Subunit - metabolism | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Signal Transduction - drug effects | Embryo, Mammalian - cytology | Fibroblasts - drug effects | Hepatitis C - virology | STAT2 Transcription Factor - genetics | Fibroblasts - cytology | Liver - cytology | Mice | STAT2 Transcription Factor - metabolism | Intestines - cytology
Journal Article
Journal Article
Transplantation Direct, ISSN 0041-1337, 05/2019, Volume 103, Issue 5, pp. 929 - 937
BACKGROUND.Tumor recurrence is a major complication following liver transplantation (LT) as treatment for hepatocellular carcinoma (HCC). Immunosuppression is... 
LIVER-TRANSPLANT RECIPIENTS | SURGERY | EVEROLIMUS | RENAL-FUNCTION | IMMUNOLOGY | CANCER | TRANSPLANTATION | IMMUNOSUPPRESSION | RECURRENCE | SIROLIMUS | MOFETIL | LONG | CYCLOSPORINE
Journal Article
Translational Research, ISSN 1931-5244, 2016, Volume 188, pp. 67 - 79
Tofacitinib is an oral Janus kinase inhibitor that is effective for the treatment of rheumatoid arthritis and shows encouraging therapeutic effects in several... 
Internal Medicine | RHEUMATOID-ARTHRITIS | MEDICINE, RESEARCH & EXPERIMENTAL | SYSTEMIC-LUPUS-ERYTHEMATOSUS | PRIMARY SJOGRENS-SYNDROME | SYNOVIAL-FLUID | REGULATORY FACTOR | I INTERFERON | LONG-TERM EXTENSION | MEDICINE, GENERAL & INTERNAL | JANUS KINASE INHIBITOR | ANTIMICROBIAL PEPTIDE | ALLOGRAFT RECIPIENTS | MEDICAL LABORATORY TECHNOLOGY | Humans | STAT Transcription Factors - metabolism | Dose-Response Relationship, Drug | Proto-Oncogene Proteins c-bcl-2 - metabolism | Interferon-alpha - genetics | Piperidines - pharmacology | Pyrroles - administration & dosage | Dendritic Cells - drug effects | Hepacivirus - physiology | Dendritic Cells - metabolism | Interferon-alpha - metabolism | Piperidines - administration & dosage | Interleukin-3 - metabolism | Pyrimidines - administration & dosage | Pyrimidines - pharmacology | Interleukin-3 - genetics | Gene Expression Regulation - drug effects | Protein Kinase Inhibitors - administration & dosage | Pyrroles - pharmacology | STAT Transcription Factors - genetics | Virus Replication | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Apoptosis - physiology | Proto-Oncogene Proteins c-bcl-2 - genetics | Virus diseases | Rheumatoid factor | Dendritic cells | Proteases | Analysis | Arthritis | Interferon | Biological response modifiers | Health aspects | Lupus | Systemic lupus erythematosus | Hepatitis C
Journal Article
European Journal of Immunology, ISSN 0014-2980, 06/2011, Volume 41, Issue 6, pp. 1663 - 1674
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 03/2019, Volume 10, p. 441
T-cell immunity in the liver is tightly regulated to prevent chronic liver inflammation in response to antigens and toxins derived from food and intestinal... 
MIGRATION | myeloid dendritic cell | PHAGOCYTOSIS | plasmacytoid dendritic cell | macrophage | human liver | MOUSE-LIVER | INDUCTION | IMMUNOLOGY | PLASMACYTOID DENDRITIC CELLS | RESPONSES | CONTAIN | REGULATORY T-CELLS | HEPATITIS-C | immunological tolerance | CROSS-PRESENTATION | Prevention | Antigens | Liver diseases | Research | T cells | Risk factors
Journal Article
Blood, ISSN 0006-4971, 07/2001, Volume 98, Issue 1, pp. 165 - 173
textabstractClonality assessment through Southern blot (SB) analysis of TCRB genes or polymerase chain reaction (PCR) analysis of TCRG genes is important for... 
Journal Article