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1. Full Text High-throughput analysis of sulfatides in cerebrospinal fluid using automated extraction and UPLC-MS/MS
by Blomqvist, Maria and Borén, Jan and Zetterberg, Henrik and Blennow, Kaj and Månsson, Jan-Eric and Ståhlman, Marcus and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine and Sahlgrenska Academy and Sahlgrenska akademin and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin
Journal of lipid research, ISSN 0022-2275, 2017, Volume 58, Issue 7, pp. 1482 - 1489
Alzheimer’s disease | Ultra-performance liquid chromatography-tandem mass spectrometry | Sulfatides | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Automation | Chromatography, High Pressure Liquid - methods | Humans | Middle Aged | Adult | Aged | Sulfoglycosphingolipids - cerebrospinal fluid | Chemical Fractionation - methods | Clinical Chemistry Tests - methods | Sulfoglycosphingolipids - isolation & purification | Tandem Mass Spectrometry - methods | Neurological diseases | Mass spectroscopy | Liquid chromatography | Glycosphingolipids | Cerebrospinal fluid | Index Medicus | sulfatides | ultra-performance liquid chromatography-tandem mass spectrometry | Methods | metachromatic leukodystrophy | dried blood | white-matter lesions | multiple-sclerosis | Klinisk medicin | tandem mass-spectrometry | Clinical Medicine | Biokemi och molekylärbiologi | normal-pressure hydrocephalus | neurological disorders | ultra-performance liquid chromatographytandem mass spectrometry | Biochemistry and Molecular Biology | Alzheimer's disease | central-nervous-system | total lipid extraction | alzheimers-disease
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2. Full Text The central role of arterial retention of cholesterol-rich apolipoprotein-B-containing lipoproteins in the pathogenesis of atherosclerosis: a triumph of simplicity
by Boren, Jan and Williams, Kevin Jon and Sahlgrenska akademin and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
Current opinion in lipidology, ISSN 0957-9672, 10/2016, Volume 27, Issue 5, pp. 473 - 483
Biochemistry & Molecular Biology | Endocrinology & Metabolism | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Protein Aggregates | Atherosclerosis - etiology | Apolipoproteins B - metabolism | Animals | Humans | Risk Factors | Apolipoproteins B - chemistry | Cholesterol - metabolism | Atherosclerosis - metabolism | Arteries - metabolism | Index Medicus | atherosclerosis | cardiovascular events | prospective randomized controlled trials | proteoglycan-binding-site | atherogenic lipoproteins | apolipoprotein-B | e-deficient mice | Mendelian randomization studies | Klinisk medicin | smooth-muscle-cells | proteoglycan | metabolic syndrome | Clinical Medicine | subendothelial retention | low-density-lipoprotein | promotes atherosclerosis | extracellular-matrix
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3. Full Text Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: Guidance for clinicians to prevent coronary heart disease
by Nordestgaard, Børge G and Chapman, M. John and Humphries, Steve E and Ginsberg, Henry N and Masana, Luis and Descamps, Olivier S and Wiklund, Olov and Hegele, Robert A and Raal, Frederick J and Defesche, Joep C and Wiegman, Albert and Santos, Raul D and Watts, Gerald F and Parhofer, Klaus G and Hovingh, G. Kees and Kovanen, Petri T and Boileau, Catherine and Averna, Maurizio and Borén, Jan and Bruckert, Eric and Catapano, Alberico L and Kuivenhoven, Jan Albert and Pajukanta, Päivi and Ray, Kausik and Stalenhoef, Anton F. H and Stroes, Erik and Taskinen, Marja-Riitta and Tybjærg-Hansen, Anne and European Atherosclerosis Soc Conse
European heart journal, ISSN 0195-668X, 12/2013, Volume 34, Issue 45, pp. 3478 - 3490
Low-density lipoprotein | Cardiovascular disease | Coronary heart disease | Cholesterol | Atherosclerosis | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology
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4. Full Text Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment
by Wiegman, Albert and Gidding, Samuel S and Watts, Gerald F and Chapman, M. John and Ginsberg, Henry N and Cuchel, Marina and Ose, Leiv and Averna, Maurizio and Boileau, Catherine and Borén, Jan and Bruckert, Eric and Catapano, Alberico L and Defesche, Joep C and Descamps, Olivier S and Hegele, Robert A and Hovingh, G. Kees and Humphries, Steve E and Kovanen, Petri T and Kuivenhoven, Jan Albert and Masana, Luis and Nordestgaard, Børge G and Pajukanta, Päivi and Parhofer, Klaus G and Raal, Frederick J and Ray, Kausik K and Santos, Raul D and Stalenhoef, Anton F. H and Steinhagen-Thiessen, Elisabeth and Stroes, Erik S and Taskinen, Marja-Riitta and Tybjærg-Hansen, Anne and Wiklund, Olov and European Atherosclerosis Soc Conse and European Atherosclerosis Society Consensus Panel and Sahlgrenska akademin and Wallenberg Laboratory and Wallenberglaboratoriet and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
European heart journal, ISSN 0195-668X, 2015, Volume 36, Issue 36, pp. 2425 - 2437
no | Familial hypercholesterolæmia | PCSK9 inhibitor | Treatment | Ezetimibe | Children | Diagnosis | Statin | Adolescents | LDL cholesterol | Consensus statement | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Economics, Medical | Genetic Testing | Humans | Middle Aged | Cost of Illness | Hyperlipoproteinemia Type II - diagnosis | Young Adult | Life Expectancy | Counseling | Atherosclerosis - diagnosis | Adult | Female | Hyperlipoproteinemia Type II - drug therapy | Child | Atherosclerosis - drug therapy | Pregnancy Complications - etiology | Carotid Intima-Media Thickness | Risk Factors | Evidence-Based Medicine | Pregnancy | Clinical Laboratory Techniques - methods | Homozygote | Medication Adherence | Diet | Adolescent | Heterozygote | Dietary Supplements | Early Diagnosis | Hyperlipoproteinemia Type II - genetics | Index Medicus | Reviews | Familial hypercholesterolaemia | Kardiologi | Cardiac and Cardiovascular Systems
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5. Full Text Overproduction of Very Low–Density Lipoproteins Is the Hallmark of the Dyslipidemia in the Metabolic Syndrome
by Adiels, Martin and Olofsson, Sven-Olof and Taskinen, Marja-Riitta and Borén, Jan and Wallenberg Laboratory and Institute of Medicine, Department of Molecular and Clinical Medicine and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Sahlgrenska akademin and Wallenberglaboratoriet and Institutionen för medicin, avdelningen för molekylär och klinisk medicin
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 07/2008, Volume 28, Issue 7, pp. 1225 - 1236
Apolipoprotein B | Stable isotopes | VLDL | Insulin resistance | Nonalcoholic fatty liver disease | Kinetics | Metabolic syndrome | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous | Blood. Blood coagulation. Reticuloendothelial system | Atherosclerosis (general aspects, experimental research) | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Blood and lymphatic vessels | Up-Regulation | Dyslipidemias - drug therapy | Humans | Liver - metabolism | Diabetes Mellitus, Type 2 - prevention & control | Insulin Resistance | Metabolic Syndrome - metabolism | Diabetes Mellitus, Type 2 - metabolism | Metabolic Syndrome - drug therapy | Disease Progression | Metabolic Syndrome - complications | Triglycerides - metabolism | Dyslipidemias - blood | Diabetes Mellitus, Type 2 - physiopathology | Lipoproteins, VLDL - blood | Lipoproteins, VLDL - metabolism | Metabolic Syndrome - physiopathology | Dyslipidemias - metabolism | Diabetes Mellitus, Type 2 - etiology | Hypolipidemic Agents - therapeutic use | Fatty Acids - metabolism | Index Medicus | Antilipemic Agents | drug therapy | Fatty Acids | Dyslipidemias | complications | Liver | Metabolic Syndrome X | Triglycerides | MEDICIN OCH HÄLSOVETENSKAP | prevention & control | Diabetes Mellitus | blood | etiology | physiopathology | Lipoproteins | Type 2 | metabolism | therapeutic use | MEDICAL AND HEALTH SCIENCES
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6. Full Text The central role of arterial retention of cholesterolrich apolipoprotein-B-containing lipoproteins in the pathogenesis of atherosclerosis: A triumph of simplicity
by Borén, Jan and Williams, Kevin Jon
Current opinion in lipidology, ISSN 0957-9672, 2016, Volume 27, Issue 5, pp. 473 - 483
Prospective randomized controlled trials | Proteoglycan | Mendelian randomization studies | Apolipoprotein-B | Atherosclerosis
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7. Full Text Lipoprotein(a) as a cardiovascular risk factor: current status
by Nordestgaard, Børge G and Chapman, M. John and Ray, Kausik and Borén, Jan and Aneotti, Felicita and Watts, Gerald F and Ginsberg, Henry and Amarenco, Pierre and Catapano, Alberico and Descamps, Olivier S and Fisher, Edward and Kovanen, Petri T and Kuivenhoven, Jan Albert and Lesnik, Philippe and Masana, Luis and Reiner, Zeljko and Taskinen, Marja-Riitta and Tokgözoglu, Lale and Tybjærg-Hansen, Anne and European Atherosclerosis Soc Conse and European Atherosclerosis Society Consensus Panel and Sahlgrenska akademin and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
European heart journal, ISSN 0195-668X, 2010, Volume 31, Issue 23, pp. 2844 - 2853
Myocardial infarction | Prevention | Lipids | Stroke | Hyperlipidemia | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Heart | Neurology | Atherosclerosis (general aspects, experimental research) | Biological and medical sciences | Myocarditis. Cardiomyopathies | Vascular diseases and vascular malformations of the nervous system | Medical sciences | Coronary heart disease | Blood and lymphatic vessels | Coronary Disease - blood | Age Factors | Cardiovascular Diseases - prevention & control | Humans | Risk Factors | Male | Mice, Transgenic | Hyperlipoproteinemias - therapy | Cardiovascular Diseases - genetics | Patient Selection | Coronary Disease - prevention & control | Animals | Coronary Disease - genetics | Sex Factors | Cardiovascular Diseases - blood | Immunoassay - methods | Female | Hyperlipoproteinemias - genetics | Mice | Lipoprotein(a) - blood | Lipoprotein(a) - genetics | Early Diagnosis | Hyperlipoproteinemias - diagnosis | Index Medicus | Life Sciences | Human health and pathology | Cardiology and cardiovascular system | Current Opinion | Kardiologi | Cardiac and Cardiovascular Systems
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8. Full Text Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing‐remitting MS
by Novakova, Lenka and Singh, Avadhesh Kumar and Axelsson, Markus and Ståhlman, Marcus and Adiels, Martin and Malmeström, Clas and Zetterberg, Henrik and Borén, Jan and Lycke, Jan and Cardell, Susanna L and Blomqvist, Maria and Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap and Wallenberg Laboratory and Institute of Medicine, Department of Molecular and Clinical Medicine and Sahlgrenska Academy and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and