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1. Full Text Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial
by Griffin, Simon J, Dr and Borch-Johnsen, Knut, Prof and Davies, Melanie J, Prof and Khunti, Kamlesh, Prof and Rutten, Guy EHM, PhD and Sandbæk, Annelli, Prof and Sharp, Stephen J, MSc and Simmons, Rebecca K, PhD and van den Donk, Maureen, PhD and Wareham, Nicholas J, Prof and Lauritzen, Torsten, Prof
The Lancet (British edition), ISSN 0140-6736, 2011, Volume 378, Issue 9786, pp. 156 - 167
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Public health. Hygiene-occupational medicine | Public health. Hygiene | General aspects | Diabetes. Impaired glucose tolerance | Prevention and actions | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Hypoglycemic Agents - therapeutic use | Humans | Middle Aged | Netherlands - epidemiology | Risk Factors | Diabetic Angiopathies - mortality | Male | Diabetes Mellitus, Type 2 - diagnosis | Mass Screening | Diabetes Mellitus, Type 2 - mortality | Diabetes Mellitus, Type 2 - therapy | Intention to Treat Analysis | Denmark - epidemiology | Female | Aged | Diabetic Angiopathies - prevention & control | Diabetes Mellitus, Type 2 - drug therapy | Outcome Assessment, Health Care | United Kingdom - epidemiology | Cluster Analysis | Type 2 diabetes | Complications and side effects | Patient outcomes | Research | Diagnosis | Cardiovascular diseases | Risk factors | Medical research | Health sciences | Biomedical research | Heart attacks | Research & development--R&D | Health services | Meetings | Mortality | Health psychology | Biochemistry | Grants | Primary care | Trust departments | Councils | Risk assessment | Blood pressure | Diabetes | Index Medicus | Abridged Index Medicus
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2. Full Text Age at initiation and frequency of screening to detect type 2 diabetes: a cost-effectiveness analysis
by Kahn, Richard, Dr and Alperin, Peter, MD and Eddy, David, MD and Borch-Johnsen, Knut, MD and Buse, John, MD and Feigelman, Justin and Gregg, Edward, PhD and Holman, Rury R, MD and Kirkman, M Sue, MD and Stern, Michael, MD and Tuomilehto, Jaakko, MD and Wareham, Nick J, Prof
The Lancet (British edition), ISSN 0140-6736, 2010, Volume 375, Issue 9723, pp. 1365 - 1374
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Public health. Hygiene-occupational medicine | Public health. Hygiene | General aspects | Diabetes. Impaired glucose tolerance | Prevention and actions | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Models, Theoretical | Quality-Adjusted Life Years | Stroke - prevention & control | Age Factors | Mass Screening - economics | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Stroke - complications | Diabetes Mellitus, Type 2 - economics | Models, Statistical | Hyperlipidemias - diagnosis | Diabetes Mellitus, Type 2 - diagnosis | Cardiovascular Diseases - complications | Cost-Benefit Analysis | Adult | Aged | Hypertension - diagnosis | Diabetes Mellitus, Type 2 - complications | Confidence intervals | Accuracy | Simulation | Prevention programs | Health services | Data collection | Cardiovascular disease | Mathematical models | Diabetes | Random variables | Index Medicus | Abridged Index Medicus
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3. Full Text Development of a Type 2 Diabetes Risk Model From a Panel of Serum Biomarkers From the Inter99 Cohort
by Janice A. Kolberg and Torben Jørgensen and Robert W. Gerwien and Sarah Hamren and Michael P. McKenna and Edward Moler and Michael W. Rowe and Mickey S. Urdea and Xiaomei M. Xu and Torben Hansen and Oluf Pedersen and Knut Borch-Johnsen
Diabetes care, ISSN 0149-5992, 07/2009, Volume 32, Issue 7, pp. 1207 - 1212
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Public health. Hygiene-occupational medicine | Public health. Hygiene | Diabetes. Impaired glucose tolerance | Miscellaneous | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Metabolic diseases | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Body Mass Index | Immunoassay | Risk Assessment | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Receptors, Interleukin-2 - blood | Risk Factors | Male | Biomarkers - blood | Insulin - blood | Case-Control Studies | Diabetes Mellitus, Type 2 - epidemiology | Adiponectin - blood | Diabetes Mellitus, Type 2 - blood | C-Reactive Protein - metabolism | Ferritins - blood | Denmark - epidemiology | Adult | Female | Blood Glucose - metabolism | Cohort Studies | Type 2 diabetes | Research | Biological markers | Risk assessment | Risk factors | Plasma | Nutrition | Biomarkers | Population | Statistical methods | Blood pressure | Diabetes | Apoptosis | Index Medicus | Original Research
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4. Full Text Early detection and treatment of type 2 diabetes reduce cardiovascular morbidity and mortality : A simulation of the results of the Anglo-Danish-Dutch study of intensive treatment in people with screen-detected diabetes in primary care (ADDITION-Europe)
by Herman, William H and Ye, Wen and Griffin, Simon J and Simmons, Rebecca K and Davies, Melanie J and Khunti, Kamlesh and Rutten, Guy E. H. M and Sandbaek, Annelli and Lauritzen, Torsten and Borch-Johnsen, Knut and Brown, Morton B and Wareham, Nicholas J
Diabetes care, ISSN 0149-5992, 08/2015, Volume 38, Issue 8, pp. 1449 - 1455
COST-EFFECTIVENESS ANALYSIS | CLINICAL-DIAGNOSIS | ADULTS | Internal Medicine | RANDOMIZED CONTROLLED-TRIAL | Endocrinology, Diabetes and Metabolism | Journal Article | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | Multicenter Study | COHORT | OUTCOMES | Advanced and Specialised Nursing | ONSET | NIDDM | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Cholesterol - blood | Humans | Middle Aged | Netherlands - epidemiology | Risk Factors | Diabetes Mellitus, Type 2 - prevention & control | Diabetic Angiopathies - mortality | Mass Screening - methods | Computer Simulation | Diabetes Mellitus, Type 2 - mortality | Denmark - epidemiology | Adult | Critical Care | Female | Aged | Blood Pressure - physiology | Primary Health Care | Diabetic Angiopathies - prevention & control | Blood Glucose - metabolism | Early Diagnosis | United Kingdom - epidemiology | Type 2 diabetes | Care and treatment | Primary health care | Mortality | Analysis | Management | Cardiovascular diseases | Risk factors | Simulation | Medical treatment | Cardiovascular disease | Diabetes | Medical screening | Morbidity | Index Medicus | Epidemiology | Health Services Research
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5. Full Text Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
by Saxena, Richa and Hivert, Marie-France and Langenberg, Claudia and Tanaka, Toshiko and Pankow, James and Vollenweider, Peter and Lyssenko, Valeriya and Bouatia-Naji, Nabila and Dupuis, Josée and Jackson, Anne and Kao, Wen and Li, Man and Glazer, Nicole and Manning, Alisa and Anluan, Jian and Stringham, Heather and Prokopenko, Inga and Johnson, Toby and Grarup, Niels and Boesgaard, Trine and Lecoeur, Cécile and Shrader, Peter and O´Connell, J.R and Ingelsson, Erik and Couper, David and Rice, Kenneth and Song, Kijoung and Aneasen, Camilla and Dina, Christian and Köttgen, Anna and Bacquer, Olivier and Pattou, François and Taneera, Jalal and Steinthorsdottir, Valgerdur and Rybin, Denis and Ardlie, Kristin and Sampson, Michael and Qi, Lu and Hoek, Mandy and Weedon, Michael and Aulchenko, Yurii and Voight, Benjamin and Grallert, Harald and Balkau, Beverley and Bergman, Richard and Bielinski, Suzette and Bonnefond, Amélie and Bonnycastle, Lori and Borch-Johnsen, K and Böttcher, Yvonne and Brunner, Eric and Buchanan, Thomas and Bumpstead, Suzannah and Cavalcanti-Proença, Christine and Charpentier, Guillaume and Chen, Yii-Der Ida and Chines, Peter and Collins, Francis and Cornelis, Marilyn and Crawford, Gabe and Delplanque, Jerome and Doney, Alex and Egan, Josephine and Erdos, Michael and Firmann, Mathieu and Forouhi, Nita and Fox, Caroline and Goodarzi, Mark and Graessler, Jürgen and Hingorani, Aroon and Isomaa, Bo and Jørgensen, Torben and Kivimaki, Mika and Kovacs, Peter and Krohn, Knut and Kumari, Meena and Lauritzen, Torsten and Lévy-Marchal, Claire and Mayor, Vladimir and McAteer, Jarred and Meyre, David and Mitchell, Braxton and Mohlke, Karen and Morken, Mario and Narisu, Narisu and Palmer, Colin and Pakyz, Ruth and Pascoe, Laura and Payne, Felicity and Pearson, Daniel and Rathmann, Wolfgang and Sandbaek, Annelli and Sayer, A.A and Scott, Laura and Sharp, Stephen and Sijbrands, Eric and Singleton, Anew and Siscovick, David and Smith, Nicholas and Sparsø, Thomas and ... and GIANT Consortium and MAGIC Investigators and GIANT consortium and MAGIC investigators and the MAGIC investigators
Nature genetics, ISSN 1061-4036, 02/2010, Volume 42, Issue 2, pp. 142 - 148
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Body Mass Index | Genome-Wide Association Study | Glucose Tolerance Test | Meta-Analysis as Topic | Diabetes Mellitus, Type 2 - genetics | Humans | RNA, Messenger - genetics | Gene Expression Regulation | Genetic Loci - genetics | Male | Gene Expression Profiling | RNA, Messenger - metabolism | Receptors, Gastrointestinal Hormone - metabolism | Incretins - genetics | Genetic Variation | Proteins - genetics | Insulin - metabolism | Receptors, Gastrointestinal Hormone - genetics | Denmark | Glucose - metabolism | Polymorphism, Single Nucleotide - genetics | Female | Adenylyl Cyclases - genetics | Type 2 diabetes | Blood sugar | Genetic variation | Physiological aspects | Genetic aspects | Research | Diagnosis | Risk factors | Studies | Hyperglycemia | Diabetes | Meta-analysis | Index Medicus | Medicin och hälsovetenskap
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6. Full Text Glycemic thresholds for diabetes-specific retinopathy: Implications for diagnostic criteria for diabetes
by Colagiuri, Stephen and Lee, Crystal M. Y and Wong, Tien Y and Balkau, Beverley and Shaw, Jonathan E and Borch-Johnsen, Knut and Detect-2 Collaboration Writing Grp and DETECT-2 Collaboration Writing Group and the DETECT-2 Collaboration Writing Group
Diabetes care, ISSN 0149-5992, 2011, Volume 34, Issue 1, pp. 145 - 150
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Public health. Hygiene-occupational medicine | Public health. Hygiene | Diabetes. Impaired glucose tolerance | Miscellaneous | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Metabolic diseases | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Young Adult | Diabetic Retinopathy - blood | Diabetic Retinopathy - diagnosis | Blood Glucose - analysis | Fasting - blood | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Adult | Aged | Diabetic Retinopathy - metabolism | Diabetic retinopathy | Blood sugar | Physiological aspects | Glycosylated hemoglobin | Research | Diagnosis | Risk factors | Studies | Hyperglycemia | Sensitivity analysis | Atherosclerosis | Data collection | Air pollution | Statistical methods | Diabetes | Epidemiology | Index Medicus | Original Research
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7. Full Text A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
by Moltke, Ida and Grarup, Niels and Jørgensen, Marit E and Bjerregaard, Peter and Treebak, Jonas T and Fumagalli, Matteo and Korneliussen, Thorfinn S and Andersen, Marianne A and Nielsen, Thomas S and Krarup, Nikolaj T and Gjesing, Anette P and Zierath, Juleen R and Linneberg, Allan and Wu, Xueli and Sun, Guangqing and Jin, Xin and Al-Aama, Jumana and Wang, Jun and Borch-Johnsen, Knut and Pedersen, Oluf and Nielsen, Rasmus and Albrechtsen, Anders and Hansen, Torben
Nature (London), ISSN 0028-0836, 08/2014, Volume 512, Issue 7513, pp. 190 - 193
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genome-Wide Association Study | Blood Glucose - analysis | Diabetes Mellitus, Type 2 - genetics | Gene Frequency | Humans | Middle Aged | Genotype | Muscle, Skeletal - metabolism | Insulin - blood | Genetic Variation | Insulin Resistance - genetics | Adult | GTPase-Activating Proteins - genetics | Codon, Nonsense - genetics | Greenland | Type 2 diabetes | Glucose metabolism | Complications and side effects | Patient outcomes | Genomics | Muscles | Development and progression | Research | Risk factors | Insulin resistance | Diabetes | Glucose | Population genetics | Insulin | Genes | Index Medicus | Medicin och hälsovetenskap
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8. Full Text Effect of population screening for type 2 diabetes and cardiovascular risk factors on mortality rate and cardiovascular events: a controlled trial among 1,912,392 Danish adults
by Simmons, Rebecca K and Griffin, Simon J and Witte, Daniel R and Borch-Johnsen, Knut and Lauritzen, Torsten and Sandbæk, Annelli
Diabetologia, ISSN 0012-186X, 11/2017, Volume 60, Issue 11, pp. 2183 - 2191
Type 2 diabetes | Screening | Medicine & Public Health | Human Physiology | Mortality rate | Metabolic Diseases | Internal Medicine | Cardiovascular disease | General practice | Population | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Cardiovascular Diseases - etiology | Cardiovascular Diseases - prevention & control | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Risk Factors | Male | Diabetes Mellitus, Type 2 - metabolism | Mass Screening - methods | Diabetes Mellitus, Type 2 - diagnosis | Denmark | Adult | Female | Aged | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - complications | Evaluation | Mortality | Chronic diseases | Family medicine | Adults | Health aspects | Heart diseases | Diabetes therapy | Motivation | Diabetes mellitus | Diabetes | Cardiovascular diseases | Health risk assessment | Coronary artery disease | Risk factors | Index Medicus
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9. Full Text Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
by Thorleifsson, G and Walters, G.B and Gudbjartsson, D.F and Steinthorsdottir, V and Sulem, P and Helgadottir, A and Styrkarsdottir, U and Gretarsdottir, S and Thorlacius, S and Jonsdottir, I and Jonsdottir, T and Olafsdottir, E.J and Olafsdottir, G.H and Jonsson, T and Jonsson, F and Borch-Johnsen, K and Hansen, T and Andersen, G and Jorgensen, T and Lauritzen, T and Aben, K.K.H and Verbeek, A.L.M and Roeleveld, N and Kampman, E and Yanek, L.R and Becker, L.C and Tryggvadottir, L and Rafnar, T and Becker, D.M and Gulcher, J and Kiemeney, L.A.L.M and Pedersen, O and Kong, A and Thorsteinsdottir, U and Stefansson, K
Nature genetics, ISSN 1061-4036, 2009, Volume 41, Issue 1, pp. 18 - 24
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Obesity | Biological and medical sciences | Metabolic diseases | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Body Mass Index | Genetic Predisposition to Disease | Genome-Wide Association Study | Quantitative Trait, Heritable | Obesity - complications | Diabetes Mellitus, Type 2 - genetics | Humans | Gene Expression Regulation | Body Weight - genetics | Obesity - genetics | Genome, Human - genetics | Base Sequence | Polymorphism, Single Nucleotide - genetics | Diabetes Mellitus, Type 2 - complications | Quantitative Trait Loci - genetics | Complications and side effects | Body mass index | Physiological aspects | Genetic aspects | Research | Single nucleotide polymorphisms | Health aspects | Risk factors | Medical research | Diabetes | Gene expression | Minority & ethnic groups | Quality control | Index Medicus | metabolic syndrome | alpha gene | metaanalysis | protein | weight | polymorphism | neurite outgrowth | overweight | body-mass index | genetic-variation
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