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Toxicological sciences, ISSN 1096-0929, 10/2012, Volume 129, Issue 2, pp. 332 - 345
Drug-induced liver injury (DILI) in humans is difficult to predict using classical in vitro cytotoxicity screening and regulatory animal studies. This explains... 
Drugs | Screening | DILI | Mitochondria | Prediction | Hepatotoxicity | Chemicals | Index Medicus | Life Sciences | Human health and pathology | Hépatology and Gastroenterology
Journal Article
Journal Article
Journal of hepatology, ISSN 0168-8278, 04/2011, Volume 54, Issue 4, pp. 773 - 794
Numerous investigations have shown that mitochondrial dysfunction is a major mechanism of drug-induced liver injury, which involves the parent drug or a... 
Gastroenterology and Hepatology | Drugs | Obesity | Oxidative stress | Mitochondria | Cell death | Lipids | Hepatotoxicity | Steatosis | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Carbohydrate Metabolism - drug effects | Reactive Oxygen Species - metabolism | Mitochondria, Liver - metabolism | Humans | Leptin - metabolism | Oxidative Phosphorylation - drug effects | Adipose Tissue - metabolism | Adiponectin - metabolism | Hepatitis C - complications | Cell Death - drug effects | Fatty Acids - metabolism | Chemical and Drug Induced Liver Injury - etiology | Diabetes Mellitus, Type 2 - complications | Genetic Predisposition to Disease | Fatty Liver - metabolism | Oxidation-Reduction | Obesity - complications | Insulin Resistance | Mitochondrial Membrane Transport Proteins - drug effects | Chemical and Drug Induced Liver Injury - genetics | Mitochondria, Liver - drug effects | Animals | Chemical and Drug Induced Liver Injury - metabolism | Models, Biological | Lipid Metabolism - drug effects | Alcoholic Intoxication - complications | Genome, Mitochondrial | Adipose Tissue - drug effects | Energy Metabolism - drug effects | Fatty Liver - etiology | Divalproex | Liver diseases | Thiols | Liver | Cytochrome P-450 | Mitochondrial DNA | Triglycerides | Stavudine | Permeability | Valproic acid | Fatty acids | Cells | Carnitine | Metabolites | Glutathione transferase | Acetaminophen | Physiological aspects | DNA polymerases | Health aspects | Zidovudine | Index Medicus | Reactive Oxygen Species | Fatty Acids | Adiponectin | Mitochondria, Liver | Life Sciences | Mitochondrial Membrane Transport Proteins | Cell Death | Diabetes Mellitus, Type 2 | Adipose Tissue | Alcoholic Intoxication | Hépatology and Gastroenterology | Oxidative Phosphorylation | Carbohydrate Metabolism | Lipid Metabolism | Drug-Induced Liver Injury | Fatty Liver | Human health and pathology | Energy Metabolism | Leptin | Hepatitis C
Journal Article
Toxicological sciences, ISSN 1096-6080, 10/2012, Volume 129, Issue 2, pp. 332 - 345
Drug-induced liver injury (DILI) in humans is difficult to predict using classical in vitro cytotoxicity screening and regulatory animal studies. This explains... 
Life Sciences & Biomedicine | Toxicology | Science & Technology | Mitochondria, Liver - drug effects | Animals | Humans | Mice | Mice, Inbred BALB C | Membrane Potential, Mitochondrial - drug effects | Chemical and Drug Induced Liver Injury - etiology | DILI | screening | drugs | mitochondria | hepatotoxicity | prediction | chemicals
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2018, Volume 9, pp. 2158 - 2158
...Author(s): Mykolas Bendorius, Indira Neeli, Fengjuan Wang, Srinivasa Reddy Bonam, Eszter Dombi, Nelly Buron, Annie Borgne-Sanchez, Joanna Poulton, Marko Radic... 
systemic lupus erythematosus | autophagy | NETosis | neuroinflammation | P140 peptide | mitochondrion | Life Sciences & Biomedicine | Immunology | Science & Technology | Autoimmunity | Lysosomes | Autophagy (Cytology) | Mitochondria | Research | Peptides | Index Medicus | Life Sciences
Journal Article
PloS one, ISSN 1932-6203, 2010, Volume 5, Issue 3, pp. e9924 - e9924
Journal Article
03/2018, ISBN 1119329701, Volume 1-2, 25
Mitochondrial dysfunction is a major mechanism whereby different drugs can induce liver injury such as cytolytic hepatitis, microvesicular and/or macrovacuolar... 
drug‐induced liver injury | hepatitis | steatosis | mitochondria | hepatotoxicity | Hepatitis | Mitochondria | Drug-induced liver injury | Hepatotoxicity | Steatosis
Book Chapter
Zebrafish, ISSN 1545-8547, 08/2020, Volume 17, Issue 4, pp. 268 - 270
In all animal species, oxygen consumption is a key process that is partially impaired in a large number of pathological situations and thus provides... 
TechnoFish—Methods | Life Sciences & Biomedicine | Developmental Biology | Zoology | Science & Technology | Larvae | Oxygen | Mitochondria | Antimycin A | Ichthyocides | Oxygen consumption | Zebrafish | Stock assessment | Freshwater fish | Electron transport | Embryos | Rotenone | Index Medicus | respiration | zebrafish larvae | oxygen consumption
Journal Article