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Statistics in Medicine, ISSN 0277-6715, 05/2018, Volume 37, Issue 10, pp. 1608 - 1624
Journal Article
Biometrics, ISSN 0006-341X, 03/2017, Volume 73, Issue 1, pp. 197 - 205
Journal Article
Journal Article
Statistics in Biopharmaceutical Research, ISSN 1946-6315, 04/2017, Volume 9, Issue 2, pp. 160 - 171
Identifying subgroups, which respond differently to a treatment, both in terms of efficacy and safety, is an important part of drug development. A well-known... 
Bootstrap | Selection bias | Lasso regression | Model selection | Model averaging | REGRESSION | SUBPOPULATIONS | BAD | STATISTICS & PROBABILITY | IDENTIFICATION | MEDICINE | SHRINKAGE | PREDICTORS | MATHEMATICAL & COMPUTATIONAL BIOLOGY
Journal Article
CPT: Pharmacometrics & Systems Pharmacology, ISSN 2163-8306, 09/2017, Volume 6, Issue 9, pp. 635 - 641
For drug development in neurodegenerative diseases such as Alzheimer's disease, it is important to understand which cognitive domains carry the most... 
Apolipoprotein E4 - genetics | Humans | Middle Aged | Genotype | Male | Cognition | Educational Status | Learning | Neuropsychological Tests | Models, Biological | Aged, 80 and over | Female | Aged | Studies | Cognition & reasoning | Alzheimers disease | Older people | Memory | Dementia | Original
Journal Article
Biometrical Journal, ISSN 0323-3847, 01/2020, Volume 62, Issue 1, pp. 53 - 68
Identifying subgroups of patients with an enhanced response to a new treatment has become an area of increased interest in the last few years. When there is... 
subgroup analyses | targeted therapies | MCP‐Mod | multiple testing
Journal Article
The Annals of Applied Statistics, ISSN 1932-6157, 6/2011, Volume 5, Issue 2B, pp. 1611 - 1631
Journal Article
Statistical Papers, ISSN 0932-5026, 11/2011, Volume 52, Issue 4, p. 985
Journal Article
Pharmaceutical Statistics, ISSN 1539-1604, 03/2017, Volume 16, Issue 2, pp. 133 - 142
Journal Article
Journal Article
Journal of Biopharmaceutical Statistics, ISSN 1054-3406, 09/2017, Volume 27, Issue 5, pp. 885 - 901
Phase II trials are intended to provide information about the dose-response relationship and to support the choice of doses for a pivotal phase III trial.... 
minimum effective dose | proof of concept | Dose finding | study design | phase II trials | dose-response curve | QUANTITATIVE-EVALUATION | STATISTICS & PROBABILITY | PAPER | COMBINING MULTIPLE COMPARISONS | RECOMMENDATIONS | SPLINES | PHARMACOLOGY & PHARMACY | RANGING TRIALS | PENALTIES | PHRMA WORKING GROUP
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Journal Article
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