Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (92) 92
Newspaper Article (72) 72
Publication (26) 26
Book Chapter (7) 7
Book Review (1) 1
Conference Proceeding (1) 1
Dissertation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (37) 37
animals (35) 35
apoptosis (31) 31
index medicus (26) 26
biochemistry & molecular biology (24) 24
mice (20) 20
article (17) 17
flow cytometry (17) 17
cell biology (15) 15
apoptosis - physiology (14) 14
apoptosis - drug effects (13) 13
potassium - metabolism (12) 12
activation (11) 11
jurkat cells (11) 11
male (11) 11
cell size (10) 10
oncology (10) 10
caspases - metabolism (9) 9
ions (9) 9
criminal sentences (8) 8
death (8) 8
dna - metabolism (8) 8
female (8) 8
k+ channels (8) 8
receiving stolen property (8) 8
cell death (7) 7
disorderly conduct (7) 7
dna fragmentation (7) 7
expression (7) 7
flow-cytometry (7) 7
gene expression profiling (7) 7
plasma-membrane depolarization (7) 7
programmed cell-death (7) 7
signal transduction (7) 7
sodium - metabolism (7) 7
cancer (6) 6
cell line (6) 6
cell shrinkage (6) 6
cell size - physiology (6) 6
criminal pleas (6) 6
cytochrome-c (6) 6
drunk driving (6) 6
gene-expression (6) 6
membrane potentials (6) 6
mice, knockout (6) 6
models, biological (6) 6
physiology (6) 6
potassium (6) 6
shrinkage (6) 6
thymocytes (6) 6
calcium (5) 5
cell line, tumor (5) 5
cells (5) 5
enzyme activation (5) 5
enzyme inhibitors - pharmacology (5) 5
gene expression (5) 5
inhibition (5) 5
rats (5) 5
thymocyte apoptosis (5) 5
toxicology (5) 5
abridged index medicus (4) 4
articles (4) 4
bcl-2 (4) 4
biochemistry (4) 4
biomedicine (4) 4
carcinogenesis (4) 4
caspase 3 (4) 4
caspases - physiology (4) 4
cell proliferation (4) 4
cell separation (4) 4
chloride channels (4) 4
correctional treatment programs (4) 4
deoxyribonucleic-acid (4) 4
dna (4) 4
dna damage (4) 4
drug trafficking (4) 4
endocrinology & metabolism (4) 4
fas (4) 4
fines & penalties (4) 4
in-vitro (4) 4
inflammation (4) 4
ion channels (4) 4
law enforcement (4) 4
lymphocytes - cytology (4) 4
lymphocytes - metabolism (4) 4
lymphocytes - physiology (4) 4
mechanisms (4) 4
mediated apoptosis (4) 4
mice, inbred c57bl (4) 4
mice, transgenic (4) 4
microscopy, confocal (4) 4
mitochondrial permeability transition (4) 4
oxidative stress (4) 4
pharmacology & pharmacy (4) 4
phosphorylation (4) 4
physiological aspects (4) 4
postal & delivery services (4) 4
potassium channels (4) 4
proteins (4) 4
public prosecutors (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text A nongenomic mechanism for “metalloestrogenic” effects of cadmium in human uterine leiomyoma cells through G protein-coupled estrogen receptor
by Liu, Jingli and Yu, Linda and Castro, Lysandra and Yan, Yitang and Sifre, Maria I and Bortner, Carl D and Dixon, Darlene
Archives of Toxicology, ISSN 0340-5761, 10/2019, Volume 93, Issue 10, pp. 2773 - 2785
Cadmium (Cd) is a ubiquitous environmental metal that is reported to be a “metalloestrogen.” Uterine leiomyomas (fibroids) are estrogen-responsive gynecologic... 
Biomedicine, general | Cadmium | Biomedicine | Environmental Health | Uterine leiomyomas | Occupational Medicine/Industrial Medicine | GPER | ERα36 | Pharmacology/Toxicology | EGFR | Cell proliferation | Matrix metalloproteinases | Estrogens | Crosstalk | Menopause | Estrogen receptors | Matrix metalloproteinase | Epidemiology | Human tissues | Neoplasms | Risk factors | Proteins | Signal transduction | Epidermal growth factor | Pathways | Xenoestrogens | Uterus | Metalloproteinase | Pretreatment | Growth factors | Binding | Myometrium | Epidermal growth factor receptors | MAP kinase | Fibroids | Hysterectomy | Risk analysis | Src protein | Gelatinase B | Gelatinase A | Heparin
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text NITRIC OXIDE REVERSES DRUG RESISTANCE BY INHIBITING ATPASE ACTIVITY OF P-GLYCOPROTEIN IN HUMAN MULTI-DRUG RESISTANT CANCER CELLS
by Sinha, Birandra K and Bortner, Carl. D and Mason, Ronald P and Cannon, Ronald E
Biochimica et biophysica acta. General subjects, ISSN 0304-4165, 12/2018, Volume 1862, Issue 12, pp. 2806 - 2814
Multi-drug resistance | Taxol | Adriamycin | P-gp protein | Nitric Oxide | Free radical
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text A nongenomic mechanism for "metalloestrogenic" effects of cadmium in human uterine leiomyoma cells through G protein-coupled estrogen receptor
by Liu, Jingli and Yu, Linda and Castro, Lysandra and Yan, Yitang and Sifre, Maria I and Bortner, Carl D and Dixon, Darlene
Archives of toxicology, ISSN 0340-5761, 08/2019, Volume 93, Issue 10, p. 2773
Cadmium (Cd) is a ubiquitous environmental metal that is reported to be a "metalloestrogen." Uterine leiomyomas (fibroids) are estrogen-responsive gynecologic... 
Leiomyoma | Cadmium | Epidermal growth factor | Analysis | Estrogen | Environmental health | Phenols | Anticoagulants (Medicine) | Cellular signal transduction | G proteins | Epidemiology | Risk factors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Ion channels and apoptosis in cancer
by Carl D. Bortner and John A. Cidlowski
Philosophical Transactions: Biological Sciences, ISSN 0962-8436, 3/2014, Volume 369, Issue 1638, pp. 1 - 9
Humans maintain a constant cell number throughout their lifespan. This equilibrium of cell number is accomplished when cell proliferation and cell death are... 
Cell growth | Cell death | HeLa cells | Chloride channels | Ion channels | Potassium channels | Neoplasia | Cells | Apoptosis | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Reporter mice express green fluorescent protein at initiation of meiosis in spermatocytes
: HSPA2-GFP REPORTER MICE
by Brown, Paula R and Odet, Fanny and Bortner, Carl D and Eddy, Edward M
genesis, ISSN 1526-954X, 12/2014, Volume 52, Issue 12, pp. 976 - 984
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Ion channels and apoptosis in cancer
by Bortner, Carl D and Cidlowski, John A
Philosophical Transactions of the Royal Society B: Biological Sciences, ISSN 0962-8436, 03/2014, Volume 369, Issue 1638, p. 20130104
Humans maintain a constant cell number throughout their lifespan. This equilibrium of cell number is accomplished when cell proliferation and cell death are... 
Ion channels | Cell death | Apoptosis | Cancer | CELL-VOLUME REGULATION | DEATH RECEPTORS | MITOCHONDRIAL POTASSIUM CHANNEL | CHLORIDE CHANNELS | cell death | apoptosis | OVARIAN-CANCER | ion channels | TUMOR-NECROSIS-FACTOR | KV1.3 CHANNELS | BIOLOGY | LEUKEMIA-CELLS | TARGETING DEATH | cancer | K+ CHANNELS | Neoplasms - metabolism | Cell Death - physiology | Ion Channels - metabolism | Necrosis - physiopathology | Models, Biological | Humans | Signal Transduction - physiology | Apoptosis - physiology | Neoplasms - physiopathology | Review
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Cell shrinkage and monovalent cation fluxes: Role in apoptosis
by Bortner, Carl D and Cidlowski, John A
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 2007, Volume 462, Issue 2, pp. 176 - 188
The loss of cell volume or cell shrinkage has been a morphological hallmark of the programmed cell death process known as apoptosis. This isotonic loss of cell... 
Apoptotic volume decrease (AVD) | Volume regulation | Chloride | Sodium | Ion channels | Cell shrinkage | Potassium | Apoptosis | potassium | cell shrinkage | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | ion channels | CULTURED CORTICAL-NEURONS | sodium | TUMOR-NECROSIS-FACTOR | BIOPHYSICS | apoptotic volume decrease (AVD) | chloride | ETOPOSIDE-INDUCED APOPTOSIS | X-RAY-MICROANALYSIS | DEPENDENT POTASSIUM CHANNELS | THYMOCYTE APOPTOSIS | PLASMA-MEMBRANE DEPOLARIZATION | volume regulation | SMOOTH-MUSCLE CELLS | HERG K+ CHANNEL | T-LYMPHOCYTES | Potassium - metabolism | Water-Electrolyte Balance - physiology | Oxidative Stress - physiology | Cell Size | Chlorine - metabolism | Ion Channels - physiology | Cytoprotection - physiology | Sodium - metabolism | Apoptosis Regulatory Proteins - metabolism | Ion Channel Gating - physiology | Models, Biological | Cations | Apoptosis - physiology | Ion Channels | Volume Regulation | Apoptotic Volume Decrease (AVD) | Cell Shrinkage
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Mitochondrial DNA-depleted A549 cells are resistant to bleomycin
by Sukhdev S Brar and Joel N Meyer and Carl D Bortner and Bennett Van Houten and William J Martin II
American Journal of Physiology, ISSN 1040-0605, 09/2012, Volume 303, Issue 5, p. L413
  Alveolar epithelial cells are considered to be the primary target of bleomycin-induced lung injury, leading to interstitial fibrosis. The molecular... 
Antibiotics | DNA damage | Mitochondrial DNA | Physiology | Drug resistance | Cells | Apoptosis
Journal Article
Details down arrow
9. Full Text Uncoupling Cell Shrinkage from Apoptosis Reveals That Na+ Influx Is Required for Volume Loss during Programmed Cell Death
by Carl D. Bortner and John A. Cidlowski
Journal of Biological Chemistry, ISSN 0021-9258, 10/2003, Volume 278, Issue 40, pp. 39176 - 39184
Cell shrinkage, or the loss of cell volume, is a ubiquitous characteristic of programmed cell death that is observed in all examples of apoptosis, independent... 
NEURONAL APOPTOSIS | EFFLUX | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEGRADATION | MECHANISMS | POTASSIUM | THYMOCYTES | CASPASE ACTIVATION | K+ CHANNELS | LYMPHOCYTES | Chromatin - metabolism | Sodium - chemistry | Jurkat Cells | Humans | Phosphatidylserines - chemistry | Nucleosomes - metabolism | Ions | Lipid Metabolism | DNA - metabolism | Sodium - metabolism | Necrosis | Potassium - chemistry | Microscopy, Confocal | Flow Cytometry | Electrophoresis, Agar Gel | Adenosine Triphosphate - metabolism | Chlorine - chemistry | Caspases - chemistry | Poly(ADP-ribose) Polymerases - chemistry | Microscopy, Fluorescence | Apoptosis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Nitric oxide reverses drug resistance by inhibiting ATPase activity of p-glycoprotein in human multi-drug resistant cancer cells
by Sinha, Birandra K and Bortner, Carl D and Mason, Ronald P and Cannon, Ronald E
BBA - General Subjects, ISSN 0304-4165, 12/2018, Volume 1862, Issue 12, pp. 2806 - 2814
Development of resistance to chemotherapy drugs is a significant problem in treating human malignancies in the clinic. Overexpression of drug efflux proteins,... 
Multi-drug resistance | Nitric Oxide | Taxol | Adriamycin | Free radical | P-gp protein | BIOCHEMISTRY & MOLECULAR BIOLOGY | ELECTRON-SPIN RESONANCE | MECHANISMS | FREE-RADICALS | SYNTHASE | ANTICANCER ACTIVITY | OVEREXPRESSION | ETOPOSIDE | BIOPHYSICS | DNA | EXPRESSION | Proteins | Anthracyclines | Nitric oxide | Drug resistance | Drug therapy | Adenosine triphosphatase | Cancer | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text The role of apoptotic volume decrease and ionic homeostasis in the activation and repression of apoptosis
by Bortner, Carl D and Cidlowski, John A
Pflügers Archiv - European Journal of Physiology, ISSN 0031-6768, 6/2004, Volume 448, Issue 3, pp. 313 - 318
The mechanism of activation and repression of apoptosis has been a central focus of many studies examining the role of programmed cell death in both normal and... 
Ion flux | Sodium | Activation | Programmed cell death | Repression | LifeSciences | Cell shrinkage | Potassium | Apoptosis | NEURONAL APOPTOSIS | PHYSIOLOGY | potassium | cell shrinkage | POTASSIUM CHANNELS | apoptosis | PROGRAMMED CELL-DEATH | sodium | NECROSIS | REGULATORY MECHANISMS | SHRINKAGE | ion flux | repression | SMOOTH-MUSCLE-CELLS | activation | programmed cell death | PLASMA-MEMBRANE DEPOLARIZATION | T-LYMPHOCYTES | K+ CHANNELS | Potassium - metabolism | Animals | Models, Biological | Homeostasis - physiology | Humans | Cell Size | Apoptosis - physiology | Sodium - metabolism | Ions - metabolism | Cells
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Bisphenol A induces human uterine leiomyoma cell proliferation through membrane-associated ERα36 via nongenomic signaling pathways
by Yu, Linda and Das, Parikshit and Vall, Alejandra J and Yan, Yitang and Gao, Xioahua and Sifre, Maria I and Bortner, Carl D and Castro, Lysandra and Kissling, Grace E and Moore, Alicia B and Dixon, Darlene
Molecular and Cellular Endocrinology, ISSN 0303-7207, 03/2019, Volume 484, pp. 59 - 68
The role of ERα36 in regulating BPA's effects and its potential as a risk factor for human uterine fibroids were evaluated. BPA at low concentrations (10  μM -... 
Nongenomic signaling | Bisphenol A | Leiomyoma cells | Estrogen receptor alpha36 (ERα36) | Estrogen Receptor alpha36 (ERα36)
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34
by Morris, Rebecca J and Bortner, Carl D and Cotsarelis, George and Reece, Jeffrey M and Trempus, Carol S and Faircloth, Randall S and Tennant, Raymond W
Journal of Investigative Dermatology, ISSN 0022-202X, 04/2003, Volume 120, Issue 4, pp. 501 - 511
It is widely believed that epithelial stem cells reside in the hair follicle bulge region. We investigated the hematopoietic stem and progenitor cell marker,... 
stem cell | keratinocyte | epidermal | Epidermal | Keratinocyte | Stem cell | LABEL-RETAINING CELLS | EPIDERMAL STEM-CELLS | MOUSE | MONOCLONAL-ANTIBODY | BASAL CELLS | HEMATOPOIETIC PROGENITOR | DERMATOLOGY | IN-VITRO | GENE-EXPRESSION | SKIN | DIFFERENTIATION | Antibody Specificity | Antigens, CD34 - analysis | Integrin alpha6 - analysis | Integrin alpha6 - immunology | Mice, Inbred C57BL | Mice, Transgenic | Keratinocytes - cytology | Stem Cells - cytology | Cell Separation - methods | Keratinocytes - chemistry | Stem Cells - chemistry | Hair Follicle - cytology | Animals | Flow Cytometry | Antigens, CD34 - immunology | Cell Division | Female | Mice | Mice, Inbred BALB C | Antigens, Surface - immunology | Antigens, Surface - analysis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Farnesol activates the intrinsic pathway of apoptosis and the ATF4-ATF3-CHOP cascade of ER stress in human T lymphoblastic leukemia Molt4 cells
by Joo, Joung Hyuck and Ueda, Eiichiro and Bortner, Carl D and Yang, Xiao-Ping and Liao, Grace and Jetten, Anton M
Biochemical Pharmacology, ISSN 0006-2952, 10/2015, Volume 97, Issue 3, pp. 256 - 268
In this study, we demonstrate that treatment of T lymphoblastic leukemic Molt4 cells with farnesol activates the apoptosome via the intrinsic pathway of... 
ER stress | Molt4 | Gene expression | Leukemia | Apoptosis | LUNG-CARCINOMA CELLS | RISK-FACTORS | DEATH | ENDOPLASMIC-RETICULUM STRESS | SACCHAROMYCES-CEREVISIAE | CYTOCHROME-C | UNFOLDED PROTEIN RESPONSE | SIGNALING PATHWAY | PERILLYL ALCOHOL | MOUSE MODEL | PHARMACOLOGY & PHARMACY | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Farnesol - pharmacology | Humans | Transcriptome - drug effects | Membrane Potential, Mitochondrial - drug effects | Activating Transcription Factor 3 - metabolism | MAP Kinase Signaling System - drug effects | Transfection | Activating Transcription Factor 4 - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Transcription Factor CHOP - metabolism | Anticarcinogenic Agents - pharmacology | Proto-Oncogene Proteins c-bcl-2 - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Cells
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Bisphenol A induces human uterine leiomyoma cell proliferation through membrane-associated ER[alpha]36 via nongenomic signaling pathways
by Yu, Linda and Das, Parikshit and Vall, Alejandra J and Yan, Yitang and Gao, Xioahua and Sifre, Maria I and Bortner, Carl D and Castro, Lysandra and Kissling, Grace E and Moore, Alicia B and Dixon, Darlene
Molecular and Cellular Endocrinology, ISSN 0303-7207, 03/2019, Volume 484, p. 59
The role of ER[alpha]36 in regulating BPA's effects and its potential as a risk factor for human uterine fibroids were evaluated. BPA at low concentrations... 
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text Complement receptor C5AR1/CD88 and dipeptidyl peptidase-4/CD26 define distinct hematopoietic lineages of dendritic cells
by Nakano, Hideki and Moran, Timothy P and Nakano, Keiko and Gerrish, Kevin E and Bortner, Carl D and Cook, Donald N
Journal of Immunology, ISSN 0022-1767, 04/2015, Volume 194, Issue 8, pp. 3808 - 3819
Differential display of the integrins CD103 and CD11b are widely used to distinguish two major dendritic cell (DC) subsets in nonlymphoid tissues. CD103(+) DCs... 
RESPONSES | MEDIATED-IMMUNITY | CD4 T-CELLS | LYMPHOID-TISSUE | MACROPHAGES | AIRWAY INFLAMMATION | ASTHMA | MICE | IMMUNOLOGY | EXPRESSION | ANTIGEN | Receptor, Anaphylatoxin C5a - genetics | Antigens, CD - immunology | CD11b Antigen - immunology | Gene Expression Regulation - immunology | Monocytes - cytology | Dendritic Cells - immunology | Cell Proliferation - physiology | Dipeptidyl Peptidase 4 - genetics | fms-Like Tyrosine Kinase 3 - immunology | Monocytes - immunology | Antigens, CD - genetics | Mice, Knockout | Organ Specificity - immunology | fms-Like Tyrosine Kinase 3 - genetics | Organ Specificity - genetics | CD11b Antigen - genetics | Animals | Integrin alpha Chains - immunology | Receptor, Anaphylatoxin C5a - immunology | Dendritic Cells - cytology | Mice | Mice, Inbred BALB C | Dipeptidyl Peptidase 4 - immunology | Integrin alpha Chains - genetics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
17. Full Text CD44 Plays a Critical Role in Regulating Diet-Induced Adipose Inflammation, Hepatic Steatosis, and Insulin Resistance
by Kang, Hong Soon and Liao, Grace and DeGraff, Laura M and Gerrish, Kevin and Bortner, Carl D and Garantziotis, Stavros and Jetten, Anton M
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e58417
CD44 is a multifunctional membrane receptor implicated in the regulation of several biological processes, including inflammation. CD44 expression is elevated... 
MACROPHAGE ACCUMULATION | RECRUITMENT | OBESITY | OSTEOPONTIN | MULTIDISCIPLINARY SCIENCES | TISSUE | GENE-EXPRESSION | PROFILING REVEALS | HYALURONAN | LIVER STEATOSIS | ROR-ALPHA | Liver - enzymology | Male | Gene Expression Profiling | Body Weight - genetics | Liver - injuries | Panniculitis - genetics | Inflammation - metabolism | Lymphocytes - immunology | Diet, High-Fat | Hyaluronan Receptors - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Fatty Liver - genetics | Lymphocytes - metabolism | Fatty Liver - metabolism | Fatty Liver - prevention & control | Adiposity - genetics | CD3 Complex - metabolism | Hyaluronan Receptors - genetics | Mice, Knockout | Animals | Insulin Resistance - genetics | Inflammation - genetics | Mice | Enzyme Activation | Panniculitis - metabolism | Adipose tissues | Type 2 diabetes | Obesity | Synthesis | Diet | Liver | Genes | Insulin resistance | Triglycerides | Inflammation | Fatty acids | Matrix metalloproteinases | Adipose tissue | Lipids | Kinases | Macrophages | Accumulation | Receptors | Biomedical materials | Fatty liver | CD44 antigen | Rodents | Biocompatibility | Osteopontin | CD36 antigen | Gene expression | Insulin | Biological activity | Steatosis | Collagen | Infiltration | Metabolic disorders | Chemokines
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights