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by George, J and Lim, J.S and Jang, S.J and Cun, Y.P and Ozretic, L and Kong, G and Leenders, F and Lu, X and Fernandez-Cuesta, L and Bosco, G and Muller, C and Dahmen, I and Jahchan, N.S and Park, K.S and Yang, D and Karnezis, A.N and Vaka, D and Torres, A and Wang, M.S and Korbel, J.O and Menon, R and Chun, S.M and Kim, D and Wilkerson, M and Hayes, N and Engelmann, D and Putzer, B and Bos, M and Michels, S and Vlasic, I and Seidel, D and Pinther, B and Schaub, P and Becker, C and Altmuller, J and Yokota, J and Kohno, T and Iwakawa, R and Tsuta, K and Noguchi, M and Muley, T and Hoffmann, H and Schnabel, P.A and Petersen, I and Chen, Y and Soltermann, A and Tischler, V and Choi, C.M and Kim, Y.H and Massion, P.P and Zou, Y and Jovanovic, D and Kontic, M and Wright, G.M and Russell, P.A and Solomon, B and Koch, I and Lindner, M and Muscarella, L.A and la Torre, A and Field, J.K and Jakopovic, M and Knezevic, J and Castanos-Velez, E and Roz, L and Pastorino, U and Brustugun, O.T and Lund-Iversen, M and Thunnissen, E and Kohler, J and Schuler, M and Botling, J and Sandelin, M and Sanchez-Cespedes, M and Salvesen, H.B and Achter, V and Lang, U and Bogus, M and Schneider, P.M and Zander, T and Ansen, S and Hallek, M and Wolf, J and Vingron, M and Yatabe, Y and Travis, W.D and Nurnberg, P and Reinhardt, C and Perner, S and Heukamp, L and Buttner, R and Haas, S.A and Brambilla, E and Peifer, M and Sage, J and Thomas, R.K and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Lungmedicin och allergologi and Uppsala universitet and Institutionen för medicinska vetenskaper
Nature, ISSN 0028-0836, 2015, Volume 524, Issue 7563, pp. 47 - 53
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. In nearly all the tumours analysed we found bi-allelic... 
NEUROENDOCRINE TUMORS | PATHWAY | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | IN-VIVO | GENES | CYCLE ARREST | NOTCH | C-KIT | MUTATIONS | CARCINOMA | Neurosecretory Systems - pathology | Receptors, Notch - metabolism | Chromosome Breakpoints | Genomics | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Receptors, Notch - genetics | Gene Expression Profiling | Tumor Suppressor Protein p53 - genetics | Small Cell Lung Carcinoma - metabolism | Tumor Suppressor Proteins - genetics | Neurosecretory Systems - metabolism | Female | Nuclear Proteins - genetics | Disease Models, Animal | Lung Neoplasms - genetics | Signal Transduction - genetics | Small Cell Lung Carcinoma - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Genome, Human - genetics | Small Cell Lung Carcinoma - pathology | Tumor Protein p73 | Animals | Cyclin D1 - genetics | Retinoblastoma Protein - genetics | Alleles | Cell Line, Tumor | Mice | Gene mutations | Analysis | Exome sequencing | Lung cancer, Small cell | Genetic aspects | Drug therapy | Cancer | Pathogenesis | Lung cancer | Genomes | Mutation | Kinases | Gene expression | Cancer therapies | Tumors | Clinical Medicine | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Cancer and Oncology | Klinisk medicin | Cancer och onkologi
Journal Article
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7575, pp. 700 - 704
Journal Article
Nature Genetics, ISSN 1061-4036, 01/2017, Volume 49, Issue 1, pp. 65 - 74
Journal Article
Nature communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 3518
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1048 - 13
Journal Article
by Paciullo, Francesco and Proietti, Marco and Bianconi, Vanessa and Nobili, Alessandro and Pirro, Matteo and Mannucci, Pier Mannuccio and Lip, Gregory Y. H and Lupattelli, Graziana and Tettamanti, Mauro and Pasina, Luca and Franchi, Carlotta and Perticone, Francesco and Salerno, Francesco and Corrao, Salvatore and Marengoni, Alessandra and Licata, Giuseppe and Violi, Francesco and Corazza, Gino Roberto and Marcucci, Maura and Eldin, Tarek Kamal and Di Blanca, Maria Pia Donatella and Lanzo, Giovanna and Astuto, Sarah and Ardoino, Ilaria and Cortesi, Laura and Prisco, Domenico and Silvestri, Elena and Cenci, Caterina and Emmi, Giacomo and Biolo, Gianni and Guarnieri, Gianfranco and Zanetti, Michela and Fernandes, Giovanni and Chiuch, Massimiliano and Vanoli, Massimo and Grignani, Giulia and Casella, Gianluca and Pulixi, Edoardo Alessandro and Bernardi, Mauro and Bassi, Silvia Li and Santi, Luca and Zaccherini, Giacomo and Mannarino, Elmo and Nuti, Ranuccio and Valenti, Roberto and Ruvio, Martina and Cappelli, Silvia and Palazzuoli, Alberto and Salvatore, Teresa and Sasso, Ferdinando Carlo and Girelli, Domenico and Olivieri, Oliviero and Matteazzi, Thomas and Barbagallo, Mario and Plances, Lidia and Alcamo, Roberta and Calvo, Luigi and Valenti, Miriam and Zoli, Marco and Arnò, Raffaella and Pasini, Franco Laghi and Capecchi, Pier Leopoldo and Bicchi, Maurizio and Palasciano, Giuseppe and Modeo, Maria Ester and Peragine, Maria and Pappagallo, Fabrizio and Pugliese, Stefania and Di Gennaro, Carla and Postiglione, Alfredo and Barbella, Maria Rosaria and De Stefano, Francesco and Cappellini, Maria Domenica and Fabio, Giovanna and Seghezzi, Sonia and De Amicis, Margherita Migone and Mancarella, Marta and Mari, Daniela and Rossi, Paolo Dionigi and Damanti, Sarah and Ottolini, Barbara Brignolo and Bonini, Giulia and Miceli, Emanuela and Lenti, Marco Vincenzo and Padula, Donatella and Murialdo, Giovanni and Marra, Alessio and Cattaneo, Federico and Secchi, Maria Beatrice and Ghelfi, Davide and Anastasio, Luigi and Sofia, Lucia and Carbone, Maria and Davì, Giovanni and Guagnano, Maria Teresa and Sestili, Simona and Mancuso, Gerardo and Calipari, Daniela and Bartone, Mosè and Meroni, Maria Rachele and ... and REPOSI Investigators
Drugs and Aging, ISSN 1170-229X, 04/2018, Volume 35, Issue 4, pp. 365 - 373
Background Among rate-control or rhythm-control strategies, there is conflicting evidence as to which is the best management approach for non-valvular atrial... 
MANAGEMENT | STROKE PREVENTION | GUIDELINES | VALIDATION | PHARMACOLOGY & PHARMACY | SCALE | INSIGHTS | GERIATRICS & GERONTOLOGY
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0168553
Journal Article
Journal of Tissue Engineering and Regenerative Medicine, ISSN 1932-6254, 02/2017, Volume 11, Issue 2, pp. 390 - 399
Journal Article
Life Sciences, ISSN 0024-3205, 08/2018, Volume 207, p. 372
Aims Interaction of Sex Hormone-Binding Globulin (SHBG) with estrogen-sensitive breast cancer cells has a protective role against estrogen exposure. No... 
Binding | Biotechnology | Estrogens | Estrogen | Sex | Breast cancer | Cell membranes | Gene expression | Proteins | Sex hormones | Womens health | Breast | Immunofluorescence
Journal Article