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Scientific Reports, ISSN 2045-2322, 2016, Volume 6, Issue 1, pp. 29503 - 29503
Journal Article
Cell Research, ISSN 1001-0602, 07/2018, Volume 28, Issue 7, pp. 719 - 729
Activation of the mitogen-activated protein kinase (MAPK) pathway is frequent in cancer. Drug development efforts have been focused on kinases in this pathway,... 
COMPREHENSIVE MOLECULAR PORTRAITS | COLON-CANCER | SURVIVAL | DRUG-SENSITIVITY | CLINICAL-TRIAL | LOBULAR BREAST-CANCER | GROWTH | C-JUN | EXPRESSION | EGFR | CELL BIOLOGY | Tyrosine | Xenotransplantation | MEK inhibitors | MAP kinase | Raf protein | Activation | Feedback loops | Drug development | Kinases | Proteins | Sensitivity | Inhibitors | Protein kinase | Coding | Xenografts | Tumor suppressor genes | Mutation | Colon | Inhibition | Prostate | Cancer | Tumors
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 5576 - 9
Many organisms have several similar transporters with different affinities for the same substrate. Typically, high-affinity transporters are expressed when... 
YEAST | GLUCOSE-TRANSPORTER HXT7 | COMPREHENSIVE CHIMERIC ANALYSIS | HEXOSE-TRANSPORT | ENZYMES | MULTIDISCIPLINARY SCIENCES | AMINO-ACID-RESIDUES | CONSTRAINTS | OPTIMIZATION | IDENTIFICATION | SACCHAROMYCES-CEREVISIAE | Glucose transporter | Glycolysis | Glucose metabolism | Affinity | Hypotheses | Computer applications
Journal Article
by Menden, Michael P and Wang, Dennis and Mason, Mike J and Szalai, Bence and Bulusu, Krishna C and Guan, Yuanfang and Yu, Thomas and Kang, Jaewoo and Jeon, Minji and Wolfinger, Russ and Nguyen, Tin and Zaslavskiy, Mikhail and Abante, Jordi and Abecassis, Barbara Schmitz and Aben, Nanne and Aghamirzaie, Delasa and Aittokallio, Tero and Akhtari, Farida S and Al-lazikani, Bissan and Alam, Tanvir and Allam, Amin and Allen, Chad and de Almeida, Mariana Pelicano and Altarawy, Doaa and Alves, Vinicius and Amadoz, Alicia and Anchang, Benedict and Antolin, Albert A and Ash, Jeremy R and Aznar, Victoria Romeo and Ba-alawi, Wail and Bagheri, Moeen and Bajic, Vladimir and Ball, Gordon and Ballester, Pedro J and Baptista, Delora and Bare, Christopher and Bateson, Mathilde and Bender, Andreas and Bertrand, Denis and Wijayawardena, Bhagya and Boroevich, Keith A and Bosdriesz, Evert and Bougouffa, Salim and Bounova, Gergana and Brouwer, Thomas and Bryant, Barbara and Calaza, Manuel and Calderone, Alberto and Calza, Stefano and Capuzzi, Stephen and Carbonell-Caballero, Jose and Carlin, Daniel and Carter, Hannah and Castagnoli, Luisa and Celebi, Remzi and Cesareni, Gianni and Chang, Hyeokyoon and Chen, Guocai and Chen, Haoran and Chen, Huiyuan and Cheng, Lijun and Chernomoretz, Ariel and Chicco, Davide and Cho, Kwang-Hyun and Cho, Sunghwan and Choi, Daeseon and Choi, Jaejoon and Choi, Kwanghun and Choi, Minsoo and Cock, Martine De and Coker, Elizabeth and Cortes-Ciriano, Isidro and Cserzö, Miklós and Cubuk, Cankut and Curtis, Christina and Daele, Dries Van and Dang, Cuong C and Dijkstra, Tjeerd and Dopazo, Joaquin and Draghici, Sorin and Drosou, Anastasios and Dumontier, Michel and Ehrhart, Friederike and Eid, Fatma-Elzahraa and ElHefnawi, Mahmoud and Elmarakeby, Haitham and van Engelen, Bo and Engin, Hatice Billur and de Esch, Iwan and Evelo, Chris and Falcao, Andre O and Farag, Sherif and Fernandez-Lozano, Carlos and Fisch, Kathleen and Flobak, Asmund and Fornari, Chiara and Foroushani, Amir B. K and Fotso, Donatien Chedom and Fourches, Denis and ... and AstraZeneca-Sanger Drug Combinatio and AstraZeneca-Sanger Drug Combination DREAM Consortium
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2674 - 17
Journal Article
Bioinformatics, ISSN 1367-4803, 12/2018, Volume 34, Issue 23, pp. 4079 - 4086
Abstract Motivation Intracellular signalling is realized by complex signalling networks, which are almost impossible to understand without network models,... 
ACTIVATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CANCER | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | ERK
Journal Article
Journal Article
ISSN 2045-2322, 2018
Many organisms have several similar transporters with different affinities for the same substrate. Typically, high-affinity transporters are expressed when... 
Journal Article
Cell, ISSN 0092-8674, 05/2018, Volume 173, Issue 6, pp. 1413 - 1425.e14
Journal Article
Bioinformatics, ISSN 1367-4803, 09/2018, Volume 34, Issue 17, pp. i997 - i1004
Abstract Motivation Signal-transduction networks are often aberrated in cancer cells, and new anti-cancer drugs that specifically target oncogenes involved in... 
COLON-CANCER | BRAF(V600E) INHIBITION | PREDICT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | ACQUIRED-RESISTANCE | Eccb 2018 | European Conference on Computational Biology Proceedings
Journal Article