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life sciences & biomedicine (23) 23
science & technology (23) 23
male (15) 15
animals (10) 10
endocrinology & metabolism (10) 10
humans (10) 10
type 2 diabetes (10) 10
biological and medical sciences (9) 9
diabetes (9) 9
aged (8) 8
female (8) 8
middle aged (8) 8
rats (8) 8
diabetes mellitus, type 2 - drug therapy (7) 7
glucagon-like peptides - analogs & derivatives (7) 7
kidney diseases (7) 7
kidneys (7) 7
rats, sprague-dawley (7) 7
diabetes mellitus (6) 6
dulaglutide (6) 6
insulin (6) 6
risk factors (6) 6
treatment outcome (6) 6
cardiovascular system & cardiology (5) 5
epidermal growth factor receptors (5) 5
glomerular filtration rate (5) 5
glucagon-like peptides - therapeutic use (5) 5
human necessities (5) 5
hygiene (5) 5
hypertension (5) 5
hypoglycemic agents - therapeutic use (5) 5
immunoglobulin fc fragments - therapeutic use (5) 5
medical or veterinary science (5) 5
medical sciences (5) 5
patients (5) 5
preparations for medical, dental, or toilet purposes (5) 5
recombinant fusion proteins - therapeutic use (5) 5
specific therapeutic activity of chemical compounds ormedicinal preparations (5) 5
blood pressure - physiology (4) 4
cardiology. vascular system (4) 4
chronic kidney failure (4) 4
diabetes mellitus, type 2 - blood (4) 4
drug administration schedule (4) 4
fundamental and applied biological sciences. psychology (4) 4
glycosylated hemoglobin (4) 4
heme oxygenase (4) 4
heme oxygenase - metabolism (4) 4
kidney - metabolism (4) 4
physiology (4) 4
research (4) 4
rodents (4) 4
urology & nephrology (4) 4
abridged index medicus (3) 3
adult (3) 3
ang ii-dependent hypertension (3) 3
arterial hypertension. arterial hypotension (3) 3
blood and lymphatic vessels (3) 3
blood pressure (3) 3
carbon monoxide (3) 3
cardiac & cardiovascular systems (3) 3
creatinine (3) 3
diabetes mellitus, type 2 - complications (3) 3
diabetes therapy (3) 3
drug therapy (3) 3
enzyme inhibitors - pharmacology (3) 3
estimated glomerular filtration rate (3) 3
glp-1 receptor agonist (3) 3
glucagon-like peptide-1 receptor - agonists (3) 3
glucagon-like peptides - administration & dosage (3) 3
immunoglobulin fc fragments - administration & dosage (3) 3
immunohistochemistry (3) 3
insulin glargine (3) 3
peripheral vascular disease (3) 3
recombinant fusion proteins - administration & dosage (3) 3
vertebrates: urinary system (3) 3
2k1c (2) 2
adolescent (2) 2
angiotensin i - metabolism (2) 2
angiotensin ii (2) 2
angiotensin ii - pharmacology (2) 2
apoptosis (2) 2
arteries (2) 2
arterioles - physiology (2) 2
biomarkers - blood (2) 2
blood glucose - drug effects (2) 2
blood glucose - metabolism (2) 2
body weight (2) 2
body weight - drug effects (2) 2
brief report (2) 2
brief reports (2) 2
cardiology and cardiovascular medicine (2) 2
cardiovascular (2) 2
cardiovascular diseases (2) 2
clinical trials (2) 2
clinical trials, phase iii as topic (2) 2
complications and side effects (2) 2
confidence intervals (2) 2
cyclooxygenase (2) 2
diabetes mellitus, type 2 - metabolism (2) 2
disease models, animal (2) 2
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1. Full Text A cross‐sectional community‐based observational study of asymptomatic SARS‐CoV‐2 prevalence in the greater Indianapolis area
by Meyers, Kristin J and Jones, Meghan E and Goetz, Iris A and Botros, Fady T and Knorr, Jack and Manner, David H and Woodward, Brad
Journal of medical virology, ISSN 0146-6615, 11/2020, Volume 92, Issue 11, pp. 2874 - 2879
pandemic | epidemiology | coronavirus | Life Sciences & Biomedicine | Science & Technology | Virology | Prevalence | Cross-Sectional Studies | Asymptomatic Infections - epidemiology | Humans | Middle Aged | Male | Fever - epidemiology | Indiana - epidemiology | Young Adult | Cities - epidemiology | Nasopharynx - virology | Adolescent | Cough - epidemiology | Public Health - statistics & numerical data | Adult | Female | Aged | COVID-19 Nucleic Acid Testing - statistics & numerical data | COVID-19 - epidemiology | Medical research | Severe acute respiratory syndrome | Medicine, Experimental | Coronaviruses | Health aspects | Epidemiology | Prevalence studies (Epidemiology) | Pandemics | Viral diseases | Health risks | Reverse transcription | Metropolitan areas | Infections | Asymptomatic | Risk analysis | Fever | Cough | Risk factors | Severe acute respiratory syndrome coronavirus 2 | Polymerase chain reaction | Confidence intervals | Disease transmission | Respiratory diseases | Index Medicus
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2. Full Text Cardiovascular safety for once-weekly dulaglutide in type 2 diabetes: A pre-specified meta-analysis of prospectively adjudicated cardiovascular events
by Ferdinand, Keith C and Botros, Fady T and Atisso, Charles M and Sager, Philip T
Cardiovascular diabetology, ISSN 1475-2840, 02/2016, Volume 15, Issue 1, pp. 38 - 38
Glucagon-like peptide-1 (GLP-1) | Type 2 diabetes | Cardiovascular events | Incretin | MACE | Meta-analysis | Cardiac & Cardiovascular Systems | Endocrinology & Metabolism | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Prospective Studies | Recombinant Fusion Proteins - adverse effects | Glucagon-Like Peptides - administration & dosage | Humans | Middle Aged | Male | Immunoglobulin Fc Fragments - administration & dosage | Protective Factors | Clinical Trials, Phase III as Topic | Glucagon-Like Peptide-1 Receptor - metabolism | Hypoglycemic Agents - administration & dosage | Cardiovascular Diseases - mortality | Female | Glucagon-Like Peptides - analogs & derivatives | Diabetes Mellitus, Type 2 - complications | Immunoglobulin Fc Fragments - adverse effects | Recombinant Fusion Proteins - administration & dosage | Cardiovascular Diseases - diagnosis | Cardiovascular Diseases - etiology | Drug Administration Schedule | Risk Assessment | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Biomarkers - blood | Randomized Controlled Trials as Topic | Blood Glucose - drug effects | Diabetes Mellitus, Type 2 - diagnosis | Glucagon-Like Peptides - adverse effects | Diabetes Mellitus, Type 2 - blood | Diabetes Mellitus, Type 2 - mortality | Aged | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Glucagon-Like Peptide-1 Receptor - agonists | Index Medicus
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3. Full Text 356-OR: Effect of Dulaglutide on Kidney Function–Related Outcomes in Type 2 Diabetes: Post Hoc Analysis from the REWIND Trial
by SHAW, JONATHAN E and BOTROS, FADY T and MALIK, RALEIGH and ATISSO, CHARLES and COLHOUN, HELEN M and GERSTEIN, HERTZEL C
Diabetes (New York, N.Y.), ISSN 0012-1797, 06/2020, Volume 69, Issue Supplement 1, p. 356
End-stage renal disease | Kidneys | Sensitivity analysis | Epidermal growth factor receptors | Death | Diabetes | Kidney diseases | Cardiovascular diseases | Diabetes mellitus (non-insulin dependent) | Glomerular filtration rate
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4. Full Text Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial
by Tuttle, Katherine R and Lakshmanan, Mark C and Rayner, Brian and Busch, Robert S and Zimmermann, Alan G and Woodward, D Bradley and Botros, Fady T
The lancet. Diabetes & endocrinology, ISSN 2213-8587, 08/2018, Volume 6, Issue 8, pp. 605 - 617
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Type 2 diabetes | Complications and side effects | Insulin glargine | Chronic kidney failure | Dosage and administration | Research | Drug therapy | Comparative analysis | Risk factors | Index Medicus
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5. Full Text 233-OR: Chronic Kidney Disease (CKD) Outcomes with Dulaglutide (DU) vs. Insulin Glargine (IG) in Type 2 Diabetes (T2D) and Moderate-to-Severe CKD by Albuminuria Status: AWARD-7
by TUTTLE, KATHERINE R and RAYNER, BRIAN L and LAKSHMANAN, MARK and WOODWARD, BRAD and KWAN, ANITA and KONIG, MANIGE and BOTROS, FADY T
Diabetes (New York, N.Y.), ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 233
End-stage renal disease | Glucose monitoring | Epidermal growth factor receptors | Diabetes mellitus | Population studies | Blood pressure | Kidney diseases | Diabetes | Diabetes mellitus (non-insulin dependent) | Insulin | Glomerular filtration rate
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6. Full Text 949-P: Dulaglutide Improves Kidney Fibrosis Biomarker Levels in Patients with Type 2 Diabetes and Moderate-to-Severe Chronic Kidney Disease
by TUTTLE, KATHERINE R and WILSON, JONATHAN M and LIN, YANZHU and QIAN, HUI-RONG and KELLY-BORUFF, KATHLEEN and GENOVESE, FEDERICA and KARSDAL, MORTEN A and DUFFIN, KEVIN L and BOTROS, FADY T
Diabetes (New York, N.Y.), ISSN 0012-1797, 06/2020, Volume 69, Issue Supplement 1, p. 949
Creatinine | Kidneys | Epidermal growth factor receptors | Collagen (type III) | Insulin | Patients | Glomerular filtration rate | Collagen | Fibrosis | Biomarkers | Diabetes | Kidney diseases | Diabetes mellitus (non-insulin dependent)
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7. Full Text Interaction between endogenously produced carbon monoxide and nitric oxide in regulation of renal afferent arterioles
by Fady T. Botros and L. Gabriel Navar
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 12/2006, Volume 291, Issue 6, pp. 2772 - 2778
Heme oxygenase | Soluble guanylate cyclase | Renal circulation | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Arterioles - physiology | Heme Oxygenase-1 - metabolism | Kidney - blood supply | Kidney - enzymology | Mesoporphyrins - pharmacology | Nitric Oxide Synthase - antagonists & inhibitors | Male | Guanylate Cyclase - antagonists & inhibitors | Microcirculation - drug effects | Quinoxalines - pharmacology | Vasoconstriction - physiology | Carbon Monoxide - physiology | Kidney - metabolism | Oxadiazoles - pharmacology | Renal Circulation - drug effects | Vasodilation - physiology | Heme Oxygenase (Decyclizing) - antagonists & inhibitors | Heme Oxygenase (Decyclizing) - metabolism | Arterioles - cytology | Enzyme Inhibitors - pharmacology | Rats | Guanylate Cyclase - metabolism | Nitric Oxide - physiology | Soluble Guanylyl Cyclase | Heme Oxygenase-1 - antagonists & inhibitors | Rats, Sprague-Dawley | Nitroarginine - pharmacology | Animals | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Nitric Oxide Synthase - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Kidneys | Carbon monoxide | Rodents | Nitric oxide | Veins & arteries | Index Medicus
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8. Full Text Nonanastomotic Biliary Strictures After Liver Transplantation
by Ito, Takahiro and Botros, Mina and Aziz, Antony and Guorgui, Jacob G and Agopian, Vatche G and Farmer, Douglas G and Busuttil, Ronald W and Kaldas, Fady M
The American surgeon, ISSN 0003-1348, 10/2020, Volume 86, Issue 10, pp. 1363 - 1367
Intervention | Syngeneic grafts | Liver | Brain death | Stenosis | Transplantation | Gender | Multivariate analysis | Grafting | Risk factors | Body mass index | Hepatitis | Allografts | Ischemia | Endoscopy | Thromboembolism | Age | Hepatic artery | Liver diseases | Anastomosis | Survival | Thrombosis | Patients | Morbidity | Donors | Liver transplantation | Index Medicus
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9. Full Text The Association Between Metabolic Syndrome and Unfavorable Features of Colorectal Cancer
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by Botros, Youssef and Asslo, Fady and Kaur, Supreet and Rizkalla, Suzette and Baddoura, Walid
The American journal of gastroenterology, ISSN 0002-9270, 10/2016, Volume 111, p. S60
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10. Full Text Effects of Dulaglutide and Insulin Glargine on Estimated Glomerular Filtration Rate in a Real-World Setting
by BOYE, KRISTINA and MODY, REEMA and WU, JIANMIN and LAGE, MAUREEN J and BOTROS, FADY T and WOODWARD, BRAD
Diabetes (New York, N.Y.), ISSN 0012-1797, 05/2018, Volume 67, Issue Supplement 1, p. 1557
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11. Full Text Endoscopic Variceal Banding as an Initial Approach to a Bleeding Duodenal Varix
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by Botros, Youssef and Asslo, Fady and Shami, Joseph and Baddoura, Walid
The American journal of gastroenterology, ISSN 0002-9270, 10/2015, Volume 110, p. S205
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12. Full Text Effects of Dulaglutide and Insulin Glargine on Estimated Glomerular Filtration Rate in a Real-world Setting
by Boye, Kristina S and Mody, Reema and Wu, Jianmin and Lage, Maureen J and Botros, Fady T and Woodward, Brad
Clinical therapeutics, ISSN 0149-2918, 08/2018, Volume 40, Issue 8, pp. 1396 - 1407
dulaglutide | glycosylated hemoglobin | estimated glomerular filtration rate | insulin glargine | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Recombinant Fusion Proteins - pharmacology | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Recombinant Fusion Proteins - therapeutic use | Male | Glomerular Filtration Rate - drug effects | Glucagon-Like Peptides - pharmacology | Renal Insufficiency - physiopathology | Female | Renal Insufficiency - complications | Immunoglobulin Fc Fragments - therapeutic use | Glucagon-Like Peptides - analogs & derivatives | Diabetes Mellitus, Type 2 - complications | Hypoglycemic Agents - therapeutic use | Insulin Glargine - therapeutic use | Treatment Outcome | Hypoglycemic Agents - pharmacology | Diabetes Mellitus, Type 2 - blood | Immunoglobulin Fc Fragments - pharmacology | Insulin Glargine - pharmacology | Creatinine - blood | Aged | Glucagon-Like Peptides - therapeutic use | Diabetes Mellitus, Type 2 - drug therapy | Type 2 diabetes | Glycosylated hemoglobin | Medical records | Insulin | Analysis | Creatinine | Therapy | Statistical analysis | Calipers | Renal function | Epidermal growth factor receptors | Laboratories | Diabetes mellitus | Impairment | Hypoglycemia | Patients | Electronic medical records | Glomerular filtration rate | Laboratory tests | Reduction | Hemoglobin | Adults | Diabetes | Kidney diseases | Diabetes mellitus (non-insulin dependent) | Electronic health records | Index Medicus
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13. Full Text Tadalafil for the treatment of pulmonary arterial hypertension: A double-blind 52-week uncontrolled extension study
by Oudiz, Ronald J and Brundage, Bruce H and Gali, Nazzareno and Ghofrani, Hossein Ardeschir and Simonneau, Gerald and Botros, Fady T and Chan, Melanie and Beardsworth, Anthony and Barst, Robyn J and PHIRST Study Grp and PHIRST Study Group
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2012, Volume 60, Issue 8, pp. 768 - 774
pulmonary arterial hypertension | PDE-5 | tadalafil | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Biological and medical sciences | Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases | Medical sciences | Pneumology | Prospective Studies | Double-Blind Method | Drug Administration Schedule | Vasodilator Agents - therapeutic use | Humans | Middle Aged | Phosphodiesterase 5 Inhibitors - administration & dosage | Antihypertensive Agents - administration & dosage | Familial Primary Pulmonary Hypertension | Male | Treatment Outcome | Antihypertensive Agents - therapeutic use | Carbolines - administration & dosage | Tadalafil | Analysis of Variance | Sulfonamides - therapeutic use | Adult | Female | Aged | Hypertension, Pulmonary - drug therapy | Phosphodiesterase 5 Inhibitors - therapeutic use | Carbolines - therapeutic use | Vasodilator Agents - administration & dosage | Index Medicus | Abridged Index Medicus
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14. Full Text Lesser eGFR Decline with Dulaglutide Regardless of Weight Changes in People with Type 2 Diabetes and Moderate to Severe Chronic Kidney Disease (AWARD-7)
by TUTTLE, KATHERINE R and LAKSHMANAN, MARK and RAYNER, BRIAN L and BUSCH, ROBERT S and ZIMMERMANN, ALAN G and WOODWARD, BRAD and BOTROS, FADY T
Diabetes (New York, N.Y.), ISSN 0012-1797, 05/2018, Volume 67, Issue Supplement 1, p. 1066
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15. Full Text Increase in heme oxygenase-1 levels ameliorates renovascular hypertension
by Botros, Fady T and Schwartzman, Michal L and Stier, Charles T and Goodman, Alvin I and Abraham, Nader G
Kidney international, ISSN 0085-2538, 12/2005, Volume 68, Issue 6, pp. 2745 - 2755
heme oxygenase | cyclooxygenase | 2K1C | hypertension | renin | aldosterone | Hypertension | Cyclooxygenase | Renin | Aldosterone | Heme oxygenase | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Heme Oxygenase-1 - metabolism | Heme - metabolism | Kidney - pathology | Aldosterone - blood | Enzyme Inhibitors - pharmacology | Protoporphyrins - pharmacology | Organ Size | Rats | Male | Hypertension, Renal - metabolism | Enzyme Activation - drug effects | Renin - blood | Metalloporphyrins - pharmacology | Rats, Sprague-Dawley | Tyrosine - analogs & derivatives | Kidney - metabolism | Tyrosine - metabolism | Animals | Juxtaglomerular Apparatus - metabolism | Dinoprostone - urine | Cyclooxygenase 2 - metabolism | Cyclooxygenase 1 - metabolism | Heme Oxygenase (Decyclizing) - metabolism | Index Medicus
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16. Full Text EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice
by Liang, Hai Po H and Liang, Hai P.o H and Kerschen, Edward J and Kerschen, Edward J and Hernandez, Irene and Hernandez, Irene and Basu, Sreemanti and Basu, Sreemanti and Zogg, Mark and Zogg, Mark and Botros, Fady and Botros, Fady and Jia, Shuang and Jia, Shuang and Hessner, Martin J and Hessner, Martin J and Griffin, John H and Griffin, John H and Ruf, Wolfram and Ruf, Wolfram and Weiler, Hartmut and Weiler, Hartmut
Blood, ISSN 0006-4971, 2015, Volume 125, Issue 18, pp. 2845 - 2854
Epcr-par2 signaling regulates myeloid cell tlr4 responses independent of coagulation | Life Sciences & Biomedicine | Hematology | Science & Technology | Endothelial Protein C Receptor | Endotoxemia - genetics | Mice, Inbred C57BL | Receptor, PAR-2 - metabolism | Cells, Cultured | Endotoxemia - chemically induced | Lipopolysaccharides | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Blood Coagulation - drug effects | Receptor, PAR-2 - agonists | Interferons - metabolism | Blood Coagulation - genetics | Blood Coagulation Factors - pharmacology | Mice | Receptors, Cell Surface - physiology | Endotoxemia - metabolism | Index Medicus | Abridged Index Medicus | 37 | Thrombosis and Hemostasis | 12
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