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Genetics in Medicine, ISSN 1098-3600, 10/2013, Volume 15, Issue 10, pp. 761 - 771
Journal Article
Journal of Personalized Medicine, ISSN 2075-4426, 2014, Volume 4, Issue 1, pp. 35 - 49
This study assessed physician attitudes toward adopting genome-guided prescribing through clinical decision support (CDS), prior to enlisting in the Clinical... 
Clinician perceptions | Genomic medicine | Clinical decision support | genomic medicine | clinical decision support | clinician perceptions
Journal Article
by Peloso, Gina M and Auer, Paul L and Bis, Joshua C and Voorman, Arend and Morrison, Alanna C and Stitziel, Nathan O and Brody, Jennifer A and Khetarpal, Sumeet A and Crosby, Jacy R and Fornage, Myriam and Isaacs, Aaron and Jakobsdottir, Johanna and Feitosa, Mary F and Davies, Gail and Huffman, Jennifer E and Manichaikul, Ani and Davis, Brian and Lohman, Kurt and Joon, Aron Y and Smith, Albert V and Grove, Megan L and Zanoni, Paolo and Redon, Valeska and Demissie, Serkalem and Lawson, Kim and Peters, Ulrike and Carlson, Christopher and Jackson, Rebecca D and Ryckman, Kelli K and Mackey, Rachel H and Robinson, Jennifer G and Siscovick, David S and Schreiner, Pamela J and Mychaleckyj, Josyf C and Pankow, James S and Hofman, Albert and Uitterlinden, Andre G and Harris, Tamara B and Taylor, Herman A and Taylor, Kent D and Stafford, Jeanette M and Reynolds, Lindsay M and Marioni, Riccardo E and Dehghan, Abbas and Franco, Oscar H and Patel, Aniruddh P and Lu, Yingchang and Hindy, George and Gottesman, Omri and Bottinger, Erwin P and Melander, Olle and Orho-Melander, Marju and Loos, Ruth J.F and Duga, Stefano and Merlini, Piera Angelica and Farrall, Martin and Goel, Anuj and Asselta, Rosanna and Girelli, Domenico and Martinelli, Nicola and Shah, Svati H and Kraus, William E and Li, Mingyao and Rader, Daniel J and Reilly, Muredach P and McPherson, Ruth and Watkins, Hugh and Ardissino, Diego and Zhang, Qunyuan and Wang, Judy and Tsai, Michael Y and Correa, Adolfo and Griswold, Michael E and Lange, Leslie A and Starr, John M and Rudan, Igor and Eiriksdottir, Gudny and Launer, Lenore J and Ordovas, Jose M and Levy, Daniel and Chen, Y.-D. Ida and Reiner, Alexander P and Hayward, Caroline and Polasek, Ozren and Deary, Ian J and Borecki, Ingrid B and Liu, Yongmei and Gudnason, Vilmundur and Wilson, James G and van Duijn, Cornelia M and Kooperberg, Charles and Rich, Stephen S and Psaty, Bruce M and Rotter, Jerome I and O’Donnell, Christopher J and Rice, Kenneth and Boerwinkle, Eric and Kathiresan, Sekar and Cupples, L. Adrienne and NHLBI GO Exome Sequencing Project and Diabetes - Cardiovascular Disease and Diabetes - kardiovaskulär sjukdom and Cardiovascular Research - Hypertension and Kardiovaskulär forskning - hypertoni and Lund University and EpiHealth: Epidemiology for Health and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 223 - 232
Journal Article
Diabetes, ISSN 0012-1797, 03/2017, Volume 66, Issue 3, pp. 763 - 778
The molecular signaling mechanisms between glomerular cell types during initiation/progression of diabetic kidney disease (DKD) remain poorly understood. We... 
GLOMERULOSCLEROSIS | CELLS | OXIDATIVE STRESS | ANTAGONIST | ATRASENTAN | MICROALBUMINURIA | DNA-DAMAGE | ENDOCRINOLOGY & METABOLISM | MICE | NEPHROPATHY | PODOCYTE DETACHMENT | Humans | Middle Aged | Diabetes Mellitus, Type 1 - metabolism | Male | Albuminuria | Chromatography, High Pressure Liquid | Young Adult | Kidney Glomerulus - ultrastructure | Flow Cytometry | Piperidines - pharmacology | Kidney Glomerulus - metabolism | Mesangial Cells - ultrastructure | Organophosphorus Compounds - pharmacology | Adult | Female | Mice, Inbred DBA | Diabetes Mellitus, Experimental - metabolism | Real-Time Polymerase Chain Reaction | Deoxyguanosine - analogs & derivatives | Microscopy, Electron, Scanning | Disease Susceptibility | DNA, Mitochondrial - metabolism | Deoxyguanosine - urine | Enzyme-Linked Immunosorbent Assay | Signal Transduction | Endothelin-1 - metabolism | Diabetic Nephropathies - metabolism | Kidney Glomerulus - drug effects | Mice, Inbred C57BL | Oxygen Consumption | Mitochondria - metabolism | Antioxidants - pharmacology | Kidney Glomerulus - pathology | Mitochondria - drug effects | Podocytes - pathology | Endothelium - drug effects | Podocytes - ultrastructure | Animals | Endothelium - metabolism | Endothelium - ultrastructure | Mesangial Cells - pathology | Receptor, Endothelin A - metabolism | Aged | Mice | Mitochondria | Reactive oxygen species | Genetic aspects | Research | Genetic transcription | Diabetic nephropathies | Complications | Klinisk medicin | Clinical Medicine
Journal Article
by Jones, G.T and Tromp, G and Kuivaniemi, H and Gretarsdottir, S and Baas, A.F and Giusti, B and Strauss, E and Hof, F.N. van 't and Webb, T.R and Erdman, R and Ritchie, M.D and Elmore, J.R and Verma, A and Pendergrass, S and Kullo, I.J and Ye, Z and Peissig, P.L and Gottesman, O and Verma, S.S and Malinowski, J and Rasmussen-Torvik, L.J and Borthwick, K.M and Smelser, D.T and Crosslin, D.R and Anade, M. de and Ryer, E.J and McCarty, C.A and Bottinger, E.P and Pacheco, J.A and Crawford, D.C and Carrell, D.S and Gerhard, G.S and Franklin, D.P and Carey, D.J and Phillips, V.L and Williams, M.J and Wei, W and Blair, R and Hill, A.A and Vasudevan, T.M and Lewis, D.R and Thomson, I.A and Krysa, J and Hill, G.B and Roake, J and Merriman, T.R and Oszkinis, G and Galora, S and Saracini, C and Abbate, R and Pulli, R and Pratesi, C and Saratzis, A and Verissimo, A.R and Bumpstead, S and Badger, S.A and Clough, R.E and Cockerill, G and Hafez, H and Scott, D.J and Futers, T.S and Romaine, S.P and Bridge, K and Griffin, K.J and Bailey, M.A and Smith, A and Thompson, M.M and Bockxmeer, F.M. van and Matthiasson, S.E and Thorleifsson, G and Thorsteinsdottir, U and Blankensteijn, J.D and Teijink, J.A and Wijmenga, C and Graaf, J. de and Kiemeney, L.A.L.M and Lindholt, J.S and Hughes, A and Bradley, D.T and Stirrups, K and Golledge, J and Norman, P.E and Powell, J.T and Humphries, S.E and Hamby, S.E and Goodall, A.H and Nelson, C.P and Sakalihasan, N and Courtois, A and Ferrell, R.E and Eriksson, P and Folkersen, L and Franco-Cereceda, A and Eicher, J.D and Johnson, A.D and Betsholtz, C and Ruusalepp, A and Franzen, O and Schadt, E.E and Bjorkegren, J.L and ... and Cardiogenics Consortium and Int Consortium Blood Pressure and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet and Vaskulärbiologi
Circulation Research, ISSN 0009-7330, 2017, Volume 120, Issue 2, pp. 341 - 353
RATIONALE: Abdominal aortic aneurysm (AAA) is a complex disease with both genetic and environmental risk factors. Together, 6 previously identified risk loci... 
computational biology | meta-analysis | genetics | aortic aneurysm abdominal | matrix metalloproteinases | genome-wide association study | C-REACTIVE PROTEIN | TRANSCRIPTION FACTORS | CARDIAC & CARDIOVASCULAR SYSTEMS | SEQUENCE VARIANT | aortic aneurysm, abdominal | SUSCEPTIBILITY LOCI | ELECTRONIC MEDICAL-RECORDS | HUMAN PREFRONTAL CORTEX | DENSITY-LIPOPROTEIN CHOLESTEROL | PERIPHERAL VASCULAR DISEASE | CANDIDATE GENE ASSOCIATION | HEMATOLOGY | RECEPTOR-RELATED PROTEIN-1 | CORONARY-ARTERY-DISEASE | Aortic Aneurysm, Abdominal - diagnosis | Genetic Predisposition to Disease - genetics | Humans | Genetic Loci - genetics | Genome-Wide Association Study - trends | Aortic Aneurysm, Abdominal - genetics | Genetic Variation - genetics | Aortic Aneurysm, Abdominal - epidemiology | Genetic Predisposition to Disease - epidemiology | Genome-Wide Association Study - methods | Diabetes mellitus | Coronary artery | Aneurysm | Aneurysms | Lipids | Cardiovascular disease | Genomes | Single-nucleotide polymorphism | Risk factors | Gelatinase B | Chromosome 1 | Interleukin 6 | Interleukin 6 receptors | Aorta | Lipoprotein (low density) receptors | Blood pressure | Chromosome 13 | Heritability | Cardiovascular diseases | Heart diseases | 10082 | Clinical Track | 10084 | 10185 | 10195 | 10014 | Medical and Health Sciences | Hematology | Medicin och hälsovetenskap | Klinisk medicin | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | aortic aneurysm | Hematologi | abdominal
Journal Article
by Liu, C and Kraja, Aldi and Smith, Jennifer A and Brody, Jennifer and Franceschini, Nora and Bis, Joshua and Rice, Kenneth and Morrison, Alanna and Lu, Yingchang and Weiss, S and Guo, Xiuqing and Palmas, Walter and Martin, Lisa and Chen, Y and Surenan, P and nos, Fotios and Cook, J.P and Auer, Paul and Chu, Auey and Giri, A and Zhao, W and Jakobsdottir, Margret and Lin, L.-A and Stafford, Jeanette M and Amin, Najaf and Mei, H and Yao, Jiefen and Voorman, Jeanine and Larson, Martin and Grove, Megan and Smith, Albert Vernon and Hwang, S.J and Chen, Han and Huan, Tianxiao and Kosova, G and Stitziel, Nathan and Kathiresan, Sekar and Samani, Nilesh and Schunkert, Heribert and Deloukas, Panagiotis and Li, Man and Fuchsberger, Christian and Pattaro, Cristian and Gorski, Mathias and Kooperberg, Charles and Papanicolaou, George and Rossouw, J.E and Faul, Jessica D and Kardia, Sharon and Bouchard, Claude and Raffel, Leslie and Uitterlinden, A.G and Franco, Oscar and Vasan, Ramachanan and O'Donnell, Christopher and Taylor, Kent and Liu, K.Y and Bottinger, Erwin and Gottesman, Rebecca and Daw, E. Warwick and Giulianini, Franco and Ganesh, Santhi and Salfati, Elias and Harris, Tamara and Launer, L.J and Dörr, Marcus and Felix, Stephan and Rettig, Rainer and Völzke, Henry and Kim, Eric and Lee, Wen-Jane and Lee, I.T and Sheu, W.H.-H and Tsosie, K.S and Edwards, D.R.V and Liu, YongMei and Correa, A and Weir, David and Völker, Uwe and Ridker, Paul and Boerwinkle, Eric and Gudnason, Vilmundur and Reiner, Alexander and Van Duijn, C.M and Borecki, Ingrid and Edwards, Todd L and Chakravarti, Aravinda and Rotter, J.I and Psaty, Bruce and Loos, Ruth and Fornage, Myriam and Ehret, Georg and Newton-Cheh, Christopher and Levy, Daniel and Chasman, Daniel and Myocardial Infarction Genetics CAR and GOT2Dgenes Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium and CKDGen Consortium and Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia and CHD Exome+ Consortium and GoT2DGenes Consortium and T2D-GENES Consortium
Nature Genetics, ISSN 1061-4036, 10/2016, Volume 48, Issue 10, pp. 1162 - 1170
Journal Article