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by White, Gemma and White, Jacqueline K and Gerdin, Anna-Karin and Karp, Natasha A and Ryder, Ed and Buljan, Marija and Bussell, James N and Salisbury, Jennifer and Clare, Simon and Ingham, Neil J and Podrini, Christine and Houghton, Richard and Estabel, Jeanne and Bottomley, Joanna R and Melvin, David G and Sunter, David and Adams, David J and Adams, Niels C and Baker, Lauren and Barnes, Caroline and Beveridge, Ryan and Cambridge, Emma and Carragher, Damian and Chana, Prabhjoat and Clarke, Kay and Hooks, Yvette and Igosheva, Natalia and Ismail, Ozama and Jackson, Hannah and Kane, Leanne and Lacey, Rosalind and Lafont, David Tino and Lucas, Mark and Maguire, Simon and McGill, Katherine and McIntyre, Rebecca E and Messager, Sophie and Mottram, Lynda and Mulderrig, Lee and Pearson, Laila and Pearson, Selina and Protheroe, Hayley J and Roberson, Laura-Anne and Salsbury, Grace and Sanderson, Mark and Sanger, Daniel and Shannon, Carl and Thompson, Paul C and Tuck, Elizabeth and Vancollie, Valerie E and Brackenbury, Lisa and Bushell, Wendy and Cook, Ross and Dalvi, Priya and Gleeson, Diane and Habib, Bishoy and Hardy, Matt and Liakath-Ali, Kifayathullah and Miklejewska, Evelina and Price, Stacey and Sethi, Debarati and Trenchard, Elizabeth and von Schiller, Dominique and Vyas, Sapna and West, Anthony P and Woodward, John and Wynn, Elizabeth and Evans, Arthur and Gannon, David and Griffiths, Mark and Holroyd, Simon and Iyer, Vivek and Kipp, Christian and Lewis, Morag and Li, Wei and Oakley, Darren and Richardson, David and Smedley, Damian and Agu, Chukwuma and Bryant, Jackie and Delaney, Liz and Gueorguieva, Nadia I and Tharagonnet, Helen and Townsend, Anne J and Biggs, Daniel and Brown, Terry and Brown, Ellen and Collinson, Adam and Dumeau, Charles-Etienne and Grau, Evelyn and Harrison, James and Harrison, Sarah and Ingle, Catherine E and Kundi, Helen and Madich, Alla and Mayhew, Danielle and Metcalf, Tom and Newman, Stuart and Pass, Johanna and Reynolds, Helen and ... and Sanger Inst Mouse Genetics Project and Sanger Institute Mouse Genetics Project
Cell, ISSN 0092-8674, 07/2013, Volume 154, Issue 2, pp. 452 - 464
Journal Article
by De Angelis, Martin Hrabě and Nicholson, George and Selloum, Mohammed and White, Jacqueline K and Morgan, Hugh and Ramirez-Solis, Ramiro and Sorg, Tania and Wells, Sara and Fuchs, Helmut and Fray, Martin and Adams, David J and Adams, Niels C and Adler, Thure and Aguilar-Pimentel, Antonio and Ali-Hadji, Dalila and Amann, Gregory and André, Philippe and Atkins, Sarah and Auburtin, Aurelie and Ayadi, Abdel and Becker, Julien and Becker, Lore and Bedu, Elodie and Bekeredjian, Raffi and Birling, Marie-Christine and Blake, Andrew and Bottomley, Joanna and Bowl, Michael R and Brault, Véronique and Busch, Dirk H and Bussell, James N and Calzada-Wack, Julia and Cater, Heather and Champy, Marie-France and Charles, Philippe and Chevalier, Claire and Chiani, Francesco and Codner, Gemma F and Combe, Roy and Cox, Roger and Dalloneau, Emilie and Dierich, André and Di Fenza, Armida and Doe, Brendan and Duchon, Arnaud and Eickelberg, Oliver and Esapa, Chris T and Fertak, Lahcen El and Feigel, Tanja and Emelyanova, Irina and Estabel, Jeanne and Favor, Jack and Flenniken, Ann and Gambadoro, Alessia and Garrett, Lilian and Gates, Hilary and Gerdin, Anna-Karin and Gkoutos, George and Greenaway, Simon and Glasl, Lisa and Goetz, Patrice and Da Cruz, Isabelle Goncalves and Götz, Alexander and Graw, Jochen and Guimond, Alain and Hans, Wolfgang and Hicks, Geoff and Hölter, Sabine M and Höfler, Heinz and Hancock, John M and Hoehndorf, Robert and Hough, Tertius and Houghton, Richard and Hurt, Anja and Ivandic, Boris and Jacobs, Hughes and Jacquot, Sylvie and Jones, Nora and Karp, Natasha A and Katus, Hugo A and Kitchen, Sharon and Klein-Rodewald, Tanja and Klingenspor, Martin and Klopstock, Thomas and Lalanne, Valerie and Leblanc, Sophie and Lengger, Christoph and Le Marchand, Elise and Ludwig, Tonia and Lux, Aline and McKerlie, Colin and Maier, Holger and Mandel, Jean-Louis and Marschall, Susan and Mark, Manuel and Melvin, David G and Meziane, Hamid and Micklich, Kateryna and Mittelhauser, Christophe and Monassier, Laurent and ... and EUMODIC Consortium
Nature Genetics, ISSN 1061-4036, 08/2015, Volume 47, Issue 9, pp. 969 - 978
The function of the majority of genes in the mouse and human genomes remains unknown. The mouse embryonic stem cell knockout resource provides a basis for the... 
EUROPHENOME | ANNOTATION | GENETICS & HEREDITY | GENOME-WIDE | EMPRESS | KNOCKOUT MICE | ACCESS | RESOURCE | Homozygote | Phenotype | Animals | Genetic Association Studies | Humans | Mice, Inbred C57BL | Molecular Sequence Annotation | Female | Heterozygote | Male | Mutation | Mice, Knockout | Research | Gene mutations | Human genome | Identification and classification | Health aspects | Consortia | Genotype & phenotype | Physiology | Genomes | Metabolism | Power
Journal Article
by Bradley, Allan and Anastassiadis, Konstantinos and Ayadi, Abdelkader and Battey, James and Bell, Cindy and Birling, Marie-Christine and Bottomley, Joanna and Brown, Steve and Bürger, Friederike and Bult, Carol and Bushell, Wendy and Collins, Francis and Desaintes, Christian and Doe, Brendan and Aris, Economides and Eppig, Janan and Finnell, Richard and Fletcher, Colin and Fray, Martin and Frendewey, David and Friedel, Roland and Grosveld, Frank and Hansen, J and Hérault, Yann and Hicks, Geoffrey and Hörlein, Aneas and Houghton, Catherine and Hrabé De Angelis, Martin and Huylebroeck, Danny and Iyer, Vivek and Jong, Pieter and Kadin, James and Kaloff, Cornelia and Kennedy, Karen and Koutsourakis, Manousos and Kent Lloyd, K and Marschall, Susan and Mason, Jeremy and McKerlie, Colin and McLeod, Michael and Melchner, Harald and Moore, Matt and Mujica, Alejano and Nagy, Anas and Nefedov, Mikhail and Nutter, Lauryl and Pavlovic, Guillaume and Peterson, Jane and Pollock, I and Ramirez-Solis, Ramiro and Rancourt, Derrick and Raspa, Marcello and Remacle, Jacques and Ringwald, Martin and Rosen, Barry and Rosenthal, Nadia and Rossant, Janet and Ruiz Noppinger, Patricia and Ryder, S and Schick, Joel Zupicich and Schnütgen, Frank and Schofield, Christopher and Seisenberger, Claudia and Selloum, Mohammed and Simpson, Elizabeth and Skarnes, William and Smedley, Damian and Stanford, William and Francis Stewart, A and Stone, Kevin and Swan, Kate and Tadepally, Hamsa and Teboul, Jean Louis and Tocchini-Valentini, Glauco and Valenzuela, David and West, Anthony and Yamamura, Ken-Ichi and Yoshinaga, Yuko and Wurst, Martin
Mammalian Genome, ISSN 0938-8990, 10/2012, Volume 23, Issue 9-10, pp. 580 - 586
textabstractIn 2007, the International Knockout Mouse Consortium (IKMC) made the ambitious promise to generate mutations in virtually every protein-coding gene... 
Life Sciences | Anatomy | Zoology | Cell Biology | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENOME | EMBRYONIC STEM-CELLS | GENETICS & HEREDITY | Mice, Knockout - genetics | Mice | Animals | Internet | Internationality
Journal Article
Cell, ISSN 0092-8674, 07/2013, Volume 154, Issue 2, p. 452
Mutations in whole organisms are powerful ways of interrogating gene function in a realistic context. We describe a program, the Sanger Institute Mouse... 
Journal Article
Journal Article
by Balmus, Gabriel and Larrieu, Delphine and Barros, Ana C and Collins, Casey and Abrudan, Monica and Demir, Mukerrem and Geisler, Nicola J and Lelliott, Christopher J and White, Jacqueline K and Karp, Natasha A and Atkinson, James and Kirton, Andrea and Jacobsen, Matt and Clift, Dean and Rodriguez, Raphael and Shannon, Carl and Sanderson, Mark and Gates, Amy and Dench, Joshua and Vancollie, Valerie and McCarthy, Catherine and Pearson, Selina and Cambridge, Emma and Isherwood, Christopher and Wilson, Heather and Grau, Evelyn and Galli, Antonella and Hooks, Yvette E and Tudor, Catherine L and Green, Angela L and Kussy, Fiona L and Tuck, Elizabeth J and Siragher, Emma J and McLaren, Robbie S. B and Swiatkowska, Agnieszka and Caetano, Susana S and Mazzeo, Cecilia Icoresi and Dabrowska, Monika H and Maguire, Simon A and Lafont, David T and Anthony, Lauren F. E and Sumowski, Maksymilian T and Bussell, James and Sinclair, Caroline and Brown, Ellen and Doe, Brendan and Wardle-Jones, Hannah and Griggs, Nicola and Woods, Mike and Kundi, Helen and McConnell, George and Doran, Joanne and Griffiths, Mark N. D and Kipp, Christian and Holroyd, Simon A and Gannon, David J and Alcantara, Rafael and Ramirez-Solis, Ramiro and Bottomley, Joanna and Ingle, Catherine and Ross, Victoria and Barrett, Daniel and Sethi, Debarati and Gleeson, Diane and Burvill, Jonathan and Platte, Radka and Ryder, Edward and Sins, Elodie and Miklejewska, Evelina and Von Schiller, Dominique and Duddy, Graham and Urbanova, Jana and Boroviak, Katharina and Imran, Maria and Reddy, Shalini Kamu and Adams, David J and Jackson, Stephen P and Sanger Mouse Genetics Project
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1 - 14
Journal Article
by Rozman, Jan and Rathkolb, Birgit and Oestereicher, Manuela A and Schütt, Christine and Ravindranath, Aakash Chavan and Leuchtenberger, Stefanie and Sharma, Sapna and Kistler, Martin and Willershäuser, Monja and Brommage, Robert and Meehan, Terrence F and Mason, Jeremy and Haselimashhadi, Hamed and Aguilar-Pimentel, Antonio and Becker, Lore and Treise, Irina and Moreth, Kristin and Garrett, Lillian and Hölter, Sabine M and Zimprich, Annemarie and Marschall, Susan and Amarie, Oana V and Calzada-Wack, Julia and Neff, Frauke and Brachthäuser, Laura and Lengger, Christoph and Stoeger, Claudia and Zapf, Lilly and Cho, Yi-Li and Da Silva-Buttkus, Patricia and Kraiger, Markus J and Mayer-Kuckuk, Philipp and Gampe, Karen Kristine and Wu, Moya and Conte, Nathalie and Warren, Jonathan and Chen, Chao-Kung and Tudose, Ilinca and Relac, Mike and Matthews, Peter and Cater, Heather L and Natukunda, Helen P and Cleak, James and Teboul, Lydia M and Clementson-Mobbs, Sharon and Szoke-Kovacs, Zsombor and Walling, Alison P and Johnson, Sara J and Codner, Gemma F and Fiegel, Tanja and Ring, Natalie and Westerberg, Henrik and Greenaway, Simon and Sneddon, Duncan and Morgan, Hugh and Loeffler, Jorik and Stewart, Michelle E and Ramirez-Solis, Ramiro and Bradley, Allan and Skarnes, William C and Steel, Karen P and Maguire, Simon A and Dench, Joshua and Lafont, David and Vancollie, Valerie E and Pearson, Selina A and Gates, Amy S and Sanderson, Mark and Shannon, Carl and Anthony, Lauren F. E and Sumowski, Maksymilian T and McLaren, Robbie S. B and Doe, Brendan and Wardle-Jones, Hannah and Griffiths, Mark N. D and Galli, Antonella and Swiatkowska, Agnieszka and Isherwood, Christopher M and Speak, Anneliese O and Cambridge, Emma L and Wilson, Heather M and Caetano, Susana S and Maguire, Anna Karin B and Adams, David J and Bottomley, Joanna and Ryder, Ed and Gleeson, Diane and Pouilly, Laurent and Rousseau, Stephane and Auburtin, Aurélie and Reilly, Patrick and Ayadi, Abdel and Selloum, Mohammed and Wood, Joshua A and Clary, Dave and Havel, Peter and Tolentino, Todd and Tolentino, Heather and Schuchbauer, Mike and Pedroia, Sheryl and ... and IMPC Consortium
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 288 - 16
Journal Article
Epigenomes, ISSN 2075-4655, 03/2019, Volume 3, Issue 1, p. 7
Most human genes are associated with promoters embedded in non-methylated, G + C-rich CpG islands (CGIs). Not all CGIs are found at annotated promoters,... 
mouse genetics | micro-RNA | Let-7
Journal Article