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Biomedical Papers, ISSN 1213-8118, 07/2015, Volume 159, Issue 2, pp. vii - vii
Journal Article
Cell Cycle, ISSN 1538-4101, 10/2012, Volume 11, Issue 20, pp. 3837 - 3850
Impaired DNA damage response pathways may create vulnerabilities of cancer cells that can be exploited therapeutically. One such selective vulnerability is the... 
predictive biomarkers | cancer treatment | DNA damage response | 53BP1 | PARP-1 inhibitor | BRCA1 | parsylation | p53 | MRN complex | synthetic lethality or viability | Proteins | Binding | Landes | Calcium | Biology | Bioscience | Cell | Cycle | Organogenesis | Cancer | Cancer treatment | Predictive biomarkers | Synthetic lethality or viability | PARsylation | STRAND BREAK REPAIR | MRE11 | DNA-DAMAGE RESPONSE | POLY(ADP-RIBOSE) POLYMERASE INHIBITION | CELL BIOLOGY | MAMMARY-TUMORS | ADP-RIBOSE POLYMERASE | IN-VITRO ASSAYS | SYNTHETIC LETHALITY | TUMOR-SUPPRESSOR | HOMOLOGOUS RECOMBINATION | Neoplasms - metabolism | Humans | DNA Repair Enzymes - genetics | Gamma Rays - therapeutic use | Gene Expression Regulation, Neoplastic | Male | Intracellular Signaling Peptides and Proteins - metabolism | DNA-Binding Proteins - metabolism | MRE11 Homologue Protein | Neoplasms - genetics | BRCA1 Protein - metabolism | DNA Repair Enzymes - metabolism | Biomarkers, Tumor - metabolism | Cell Cycle Proteins - genetics | Female | Antineoplastic Agents - pharmacology | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Recombinational DNA Repair - drug effects | Carcinoma - drug therapy | Genes, MDR | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Cell Cycle Proteins - metabolism | Enzyme Inhibitors - pharmacology | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Poly(ADP-ribose) Polymerase Inhibitors | Neoplasms - drug therapy | BRCA1 Protein - genetics | Drug Resistance, Neoplasm - genetics | Poly(ADP-ribose) Polymerases - metabolism | BRCA2 Protein - metabolism | Poly(ADP-ribose) Polymerases - genetics | Cell Line, Tumor | Recombinational DNA Repair - radiation effects | Biomarkers, Tumor - genetics | DNA Damage | Poly (ADP-Ribose) Polymerase-1 | Tumor Suppressor p53-Binding Protein 1 | Camptothecin - pharmacology | BRCA2 Protein - genetics | Index Medicus | Report
Journal Article
Journal Article
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 5695 - 10
Skp2 is a crucial component of SCFskP2 E3 ubiquitin ligase and is often overexpressed in various types of cancer, including prostate cancer (PCa). The... 
TRANSITION | MOLECULAR SIGNATURE | STEM-CELLS | P27 | MULTIDISCIPLINARY SCIENCES | ACQUISITION | DOCETAXEL RESISTANCE | DEPENDENT KINASE INHIBITOR | EMT | PROGRESSION | P27(KIP1) | Ubiquitin | Phenotypes | Mesenchyme | Hyperplasia | Genotype & phenotype | Skp2 protein | CD44 antigen | Cell lines | Stem cells | Localization | Prostate cancer | Prostate | Ubiquitin-protein ligase
Journal Article
Current Drug Targets, ISSN 1389-4501, 01/2014, Volume 15, Issue 12, pp. 1166 - 1175
Journal Article
Stem Cell Research, ISSN 1873-5061, 03/2019, Volume 35, pp. 101405 - 101405
Human induced pluripotent stem cell line was generated from commercially available primary human prostate fibroblasts HPrF derived from a fetus, aged... 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Fibroblasts | Research | Gene expression | Stem cells | Index Medicus
Journal Article
Stem Cell Research, ISSN 1873-5061, 12/2018, Volume 33, pp. 255 - 259
A human induced pluripotent stem cell line was generated from cancer-associated fibroblasts of a 68-years old patient with diagnosed prostate adenocarcinoma... 
CHROMOSOME | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Stem cells | Fibroblasts | Research | Diagnosis | Gene expression | Cell differentiation | Prostate cancer | Index Medicus
Journal Article
Journal Article
Journal of Assisted Reproduction and Genetics, ISSN 1058-0468, 8/2018, Volume 35, Issue 8, pp. 1407 - 1417
Journal Article
Molecular Oncology, ISSN 1574-7891, 04/2018, Volume 12, Issue 4, pp. 561 - 576
A number of prostate cancer ( PC a)‐specific genomic aberrations (denominated BRCA ness genes) have been discovered implicating sensitivity to PARP inhibition... 
prostate cancer | olaparib | combination therapy | maintenance therapy | inhibition | PARP | endocrine therapy | PARP inhibition | POLY(ADP-RIBOSE) POLYMERASE | OVARIAN-CANCER | MODEL | GENE | ONCOLOGY | DNA-REPAIR DEFECTS | VELIPARIB ABT-888 | INHIBITOR | PHASE-I | s
Journal Article