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Diabetes, ISSN 0012-1797, 04/2009, Volume 58, Issue 4, pp. 803 - 812
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2011, Volume 108, Issue 35, pp. 14608 - 14613
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, pp. e21187 - e21187
Environmental factors, such as the macronutrient composition of the diet, can have a profound impact on risk of diabetes and metabolic syndrome. In the present... 
MAMMALIAN TARGET | SKELETAL-MUSCLE | PROTEIN INTAKE | GLUCOSE-METABOLISM | PHOSPHORYLATION | AMINO-ACIDS | MULTIDISCIPLINARY SCIENCES | BLOOD-GLUCOSE | WEIGHT-LOSS | INDUCED OBESITY | RECEPTOR SUBSTRATE-1 | Inflammation - pathology | Metabolomics | Leucine - pharmacology | Liver - pathology | Liver - enzymology | Body Weight - drug effects | Leucine - therapeutic use | Liver - drug effects | Dietary Fats - pharmacology | Adenylate Kinase - metabolism | Dietary Fats - administration & dosage | Glucose Tolerance Test | Adiposity - drug effects | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Adipose Tissue - pathology | Insulin Resistance | Leucine - administration & dosage | Fatty Liver - drug therapy | Feeding Behavior - drug effects | Insulin - metabolism | Animals | Diet | Muscles - enzymology | Signal Transduction - drug effects | Muscles - drug effects | Mice | Adipose Tissue - drug effects | Dietary Supplements | Type 2 diabetes | Drinking water | Metabolites | RNA | Liver | Physiological aspects | Amino acids | Insulin resistance | Glucose | Fatty acids | Dextrose | Tricarboxylic acid cycle | Phosphorylation | Adipose tissue | Homeostasis | Environmental changes | mRNA | Leucine | Kinases | High fat diet | Fatty liver | Rodents | Animal tissues | Obesity | Abnormalities | Diabetes mellitus | Health risks | Environmental factors | Inflammation | Metabolism | Insulin | Body weight gain | Cholesterol | Intermediates | Ribosomal protein S6 kinase | Glucose tolerance | Signaling | Insulin receptor substrate 1 | Food intake | Metabolic disorders | Index Medicus
Journal Article
Diabetes, ISSN 0012-1797, 03/2013, Volume 62, Issue 3, pp. 864 - 874
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 1881
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are effective treatments for improving glucose control and reducing cardiovascular events in patients with... 
Cardiovascular system | Urine | Fasting | Ketones | Liver | Homeostasis | Glucose | Palmitic acid | Insulin | Intermediates | Fatty liver | Sodium | Plasma levels | Oxidation | Pancreas
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 1953
Increasing brown adipose tissue abundance or activity or converting white into brown adipocytes holds promise for the treatment of type 2 diabetes and obesity.... 
Obesity | Fibroblast growth factor | Diabetes mellitus | Preadipocytes | Energy expenditure | mRNA | Adipocytes | Synergism | Insulin | Steatosis | Fatty liver | Uncoupling protein 1 | Rosiglitazone | Agonists | Diabetes | Adipose tissue (brown) | Diabetes mellitus (non-insulin dependent)
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2010, Volume 16, Issue 4, pp. 438 - 445
Class Ia phosphoinositide 3-kinase (PI3K), an essential mediator of the metabolic actions of insulin, is composed of a catalytic (p110 alpha or p110 beta) and... 
MEDICINE, RESEARCH & EXPERIMENTAL | METABOLIC SYNDROME | PHOSPHATIDYLINOSITOL 3-KINASE | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOPLASMIC-RETICULUM STRESS | P85-ALPHA SUBUNIT | CELL BIOLOGY | SKELETAL-MUSCLE | MESSENGER-RNA | INSULIN-RESISTANCE | PURIFICATION METHOD | ADIPOSE-TISSUE | Insulin - physiology | Endoplasmic Reticulum - metabolism | Activating Transcription Factor 6 | Phosphatidylinositol 3-Kinases - metabolism | Cell Nucleus - physiology | X-Box Binding Protein 1 | Endoribonucleases - physiology | Gene Knockdown Techniques | Trans-Activators - physiology | DNA-Binding Proteins - metabolism | Cell Nucleus - metabolism | Membrane Proteins - physiology | Stress, Physiological - physiology | Cell Line | Unfolded Protein Response - drug effects | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Protein-Serine-Threonine Kinases - physiology | Liver - metabolism | Endoplasmic Reticulum - physiology | Regulatory Factor X Transcription Factors | Transcription Factors - metabolism | Animals | Tunicamycin - pharmacology | Liver - physiology | Phosphatidylinositol 3-Kinases - physiology | Mice | Apoptosis - physiology | Unfolded Protein Response - physiology | Transcription factors | Physiological aspects | Causes of | Insulin resistance | Genetic aspects | Research | Binding proteins | Protein kinases | Catalysis | Kinases | Metabolism | Protein folding | Insulin | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2014, Volume 124, Issue 8, pp. 3339 - 3351
miRNAs are important regulators of biological processes in many tissues, including the differentiation and function of brown and white adipocytes. The... 
MEDICINE, RESEARCH & EXPERIMENTAL | MUSCULAR HYPERTROPHY | OBESITY | ENERGY-EXPENDITURE | BEIGE ADIPOCYTES | GLUCOSE-METABOLISM | GENE-EXPRESSION | BROWN ADIPOSE-TISSUE | INSULIN SENSITIVITY | FAT-CELL | WHITE ADIPOCYTES | Adipocytes, White - cytology | Adipocytes, Brown - metabolism | HIV-Associated Lipodystrophy Syndrome - genetics | Humans | Male | MicroRNAs - metabolism | Cell Differentiation - genetics | DEAD-box RNA Helicases - deficiency | Female | DEAD-box RNA Helicases - metabolism | Cell Differentiation - physiology | Disease Models, Animal | Ribonuclease III - genetics | Ribonuclease III - metabolism | RNA Processing, Post-Transcriptional | Down-Regulation | Insulin Resistance | Lipodystrophy - metabolism | Ribonuclease III - deficiency | Mice, Knockout | Lipodystrophy - genetics | DEAD-box RNA Helicases - genetics | HIV-Associated Lipodystrophy Syndrome - pathology | Animals | Energy Metabolism | Lipodystrophy - pathology | HIV-Associated Lipodystrophy Syndrome - metabolism | Mice | MicroRNAs - genetics | Adipocytes, Brown - cytology | Cohort Studies | Adipose tissues | Physiological aspects | Lipodystrophy | Genetic aspects | MicroRNA | Research | Body fat | Mortality | Adipocytes | Metabolism | Gene expression | Abdomen | Studies | Hospitals | Rodents | Insulin resistance | Diabetes | Metabolic disorders | Age | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2006, Volume 103, Issue 17, pp. 6676 - 6681
Journal Article
Diabetes, ISSN 0012-1797, 08/2016, Volume 65, Issue 8, pp. 2201 - 2213
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 40, pp. 14512 - 14517