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EMBO Molecular Medicine, ISSN 1757-4676, 06/2010, Volume 2, Issue 6, pp. 211 - 230
Journal Article
Journal Article
Autophagy, ISSN 1554-8627, 12/2014, Volume 10, Issue 12, pp. 2122 - 2142
The triple-negative breast cancer (TN BC) subtype is the most aggressive form of invasive BC. Despite intensive efforts to improve BC treatments, patients with... 
YAP1 | PDX, patient-derived xenografted tumor | Ctrl, control | TGI, tumor growth inhibition | LC3B | MAP1LC3B/LC3B, microtubule-associated protein one light chain 3 β | ATG, autophagy-related | BECN1, Beclin 1, autophagy related | YAP1, Yes-associated protein 1 | sem, standard error of mean | breast cancers | BafA1, bafilomycin A | TN BC, triple-negative breast cancer | 3-dimensional culture | IHC, immunohistochemistry | BC, breast cancer | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | three-MA, 3-methyladenine | autophagy | ACTB, actin, β | EBSS, Earle's balanced salt solution | TCGA, The Cancer Genome Atlas | 3D, 3-dimensions | prognosis | OS, overall survival | 1 | i.p., intra-peritoneal | AP2A1/adaptin, adaptor-related protein complex 2, α 1 subunit | AC, adriamycin and cyclophosphamide | response to treatment | ERBB2/HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 | HScore, histological scoring | Lum, Luminal | DFS, disease-free survival | Prognosis | Breast cancers | Response to treatment | Autophagy | STEM-CELLS | INDUCED APOPTOSIS | TARGETING AUTOPHAGY | LIGHT-CHAIN 3A | DRUG-RESISTANCE | CELL BIOLOGY | PRECLINICAL MODELS | GENE-EXPRESSION | TUMOR-SUPPRESSOR | METABOLIC STRESS | TUMORIGENESIS | Receptors, Estrogen - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Receptor, ErbB-2 - metabolism | Treatment Outcome | Antineoplastic Agents - therapeutic use | Autophagy - drug effects | Triple Negative Breast Neoplasms - therapy | Receptors, Estrogen - drug effects | Animals | Triple Negative Breast Neoplasms - diagnosis | Biomarkers, Tumor - metabolism | Female | Mice
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 05/2016, Volume 8, Issue 5, pp. 527 - 549
Anti‐cancer drugs often increase reactive oxygen species (ROS) and cause DNA damage. Here, we highlight a new cross talk between chronic oxidative stress and... 
Ubiquitin | Oxidative stress | Reactive oxygen species | Ontology | DNA damage | Genes | Breast cancer | Kinases | Cancer therapies | Patients | DNA repair | Genomic instability | Antioxidants | Proteins | Ubiquitination | Chemotherapy | Cell cycle | Fibroblasts | Aging | Physiology | Deoxyribonucleic acid--DNA | Ubiquitin-protein ligase | Tumors
Journal Article
The EMBO Journal, ISSN 0261-4189, 09/2005, Volume 24, Issue 18, pp. 3313 - 3324
Regulation of gene expression underlies cell differentiation and organogenesis. Both transcription factors and chromatin modifiers are crucial for this... 
cell differentiation | proliferation | transcriptome | Cre‐loxP | INI1 | Cre-loxP | Proliferation | Cell differentiation | Transcriptome | PROTEIN | TUMOR SUPPRESSION | BRG1 | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | CELL-CYCLE ARREST | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | MICE | INHIBITOR | EXPRESSION | Cell Proliferation | Epithelial Cells - metabolism | Transcription Factors - deficiency | Hepatocytes - metabolism | DNA-Binding Proteins - deficiency | Protein Subunits - metabolism | DNA-Binding Proteins - metabolism | SMARCB1 Protein | Hepatocytes - cytology | Glycogen - metabolism | Gene Expression Regulation, Developmental | Gene Deletion | Cell Differentiation | Epithelial Cells - cytology | Protein Subunits - genetics | Cell Line | Chromosomal Proteins, Non-Histone - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Microscopy, Electron | Organ Specificity | Cell Adhesion | Chromosomal Proteins, Non-Histone - genetics | Transcription Factors - metabolism | Embryo Loss | Animals | Glucose - metabolism | Protein Binding | Mice | Protein Subunits | Glycogen | Chromosomal Proteins, Non-Histone | Epithelial Cells | Glucose | Cellular Biology | Life Sciences | Hepatocytes | Transcription Factors | Development Biology | Subcellular Processes | DNA-Binding Proteins
Journal Article
Journal Article
EMBO reports, ISSN 1469-221X, 03/2008, Volume 9, Issue 3, pp. 267 - 272
The mammalian heterochromatin protein 1 (HP1) family of proteins was recently shown to be involved in transient repression of inducible promoters. One of these... 
mitogen‐activated protein kinases | histone code | HIV1 | RNA polymerase II | CHROMATIN | PHOSPHORYLATION | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HP1 | HETEROCHROMATIN PROTEIN-1 | CELL BIOLOGY | INDUCED GENE-EXPRESSION | mitogen-activated protein kinases | NF-KAPPA-B | HISTONE H3 METHYLATION | T-CELLS | RNA-POLYMERASE | Scientific Report
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 06/1999, Volume 19, Issue 6, pp. 3931 - 3939
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
GLUCOCORTICOID RECEPTOR | NUCLEAR MATRIX | TRANSCRIPTIONAL ACTIVATION | SWI/SNF COMPLEX | CHROMATIN-REMODELING COMPLEX | RETINOBLASTOMA PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | SWI-SNF COMPLEX | IFN-BETA GENE | HISTONE DEACETYLASE | ESTROGEN-RECEPTOR | CELL BIOLOGY | Gene Expression
Journal Article
EMBO Reports, ISSN 1469-221X, 03/2008, Volume 9, Issue 3, pp. 267 - 272
  The mammalian heterochromatin protein 1 (HP1) family of proteins was recently shown to be involved in transient repression of inducible promoters. One of... 
Signal transduction | RNA polymerase | Cellular biology | Kinases | Human immunodeficiency virus--HIV
Journal Article
EMBO reports, ISSN 1469-221X, 03/2008, Volume 9, Issue 3, p. 267
The mammalian heterochromatin protein 1 (HP1) family of proteins was recently shown to be involved in transient repression of inducible promoters. One of these... 
Chromatin - metabolism | Genes, Switch | Jurkat Cells | Humans | RNA Polymerase II - metabolism | HIV-1 - genetics | Promoter Regions, Genetic - genetics | Chromosomal Proteins, Non-Histone - genetics | Protein Transport | Gene Expression Regulation, Viral | Transcription, Genetic | Enzyme Activation | HeLa Cells | Terminal Repeat Sequences
Journal Article